Clinical trials: Sleep-wake Analysis
OSA - Obstructive Sleep Apnea
OSA Patients' and Bed-Partners' Illness Perceptions in CPAP Therapy Adaptation Process
This study explores how psychological and relationship factors influence the success of CPAP therapy in people with Obstructive Sleep Apnea (OSA) and their partners.
- Trial name
- CPAP-IPA (NCT07150611)
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Interoception, Perceived Stress
Interoceptive Awareness, Perceived Stress, and Physical Performance in Sport Sciences Students
This cross-sectional observational study examined the relationships between interoceptive awareness, perceived stress, state and trait anxiety, sleep quality, and physical performance indicators in university-level sport sciences…
- Conditions
- Interoception, Perceived Stress, Anxiety, Sleep Quality
- Trial name
- NCT07696234
- Testing
- Psychological and Physical Performance Assessment Battery
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Inonu University
Parkinson Disease, REM Sleep Behavior Disorder
Implementing a National Biobank of PD With WGS and Functional Assessment of Polygenic Inheritance by iPSC Technology
The genetic complexity and heterogeneity of the sporadic forms of Parkinson's disease (PD) are posing a formidable challenge to disentangle their direct molecular causes.
- Trial name
- NCT05721911
- Testing
- whole genome sequencing
- Where
- Italy
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Enlargement of Tonsil or Adenoid
Bioclinical Profile of Adenotonsillar Hypertrophy in the Pediatric Population
Adenotonsillar hypertrophy is the principal cause of obstructive sleep apnea of childhood, yet little is known with regard to its pathophysiologic and molecular mechanisms.
- Trial name
- NCT03541434
- Testing
- Complete Blood Count, Tympanometry, Tonsillectomy and/or adenoidectomy
- Where
- 2 sites in Greece
- Volunteers
- 134 people
- Sponsor
- University of Patras
Parkinson Disease, REM Sleep Behavior Disorder
Detecting Parkinson's Disease Through Speech Analysis
Speech is an important indicator of motor function and movement coordination and can be extremely sensitive to involvement in the course of neurologic diseases.
- Trial name
- NCT03133611
- Testing
- Speech assessment, Routine clinical assessment
- Where
- 7 sites in United States, Austria and 5 more
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Czech Technical University in Prague
Restless Leg Syndrome
The Suggested Immobilization Test With Exploratory Heart Rate Variability Analysis for Diagnosis of Restless Legs Syndrome
Restless leg syndrome (RLS) is not uncommon and can also affect people's health and quality of life. Mainly, RLS is diagnosed based on clinical criteria subjectively.
- Trial name
- NCT07110961
- Testing
- A suggested immobilization test (SIT)
- Where
- Thailand
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Bruxism, Sleep-Related
Smartwatch Analysis of Sleep Bruxism
This study aims to investigate the differences in sleep stages and total sleep duration between individuals diagnosed with sleep bruxism and healthy controls.
- Trial name
- NCT07453121
- Testing
- Smartwatch-based Sleep Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Cappadocia University
Obstructive Sleep Apnoea (OSA)
Entropy-based Physiological Signal Analysis in Patients With Obstructive Sleep Apnoea
This observational study is being undertaken as a part of a Master of Research (MRes) in Clinical Research programme. Its goal is to learn about how continuous positive airway pressure (CPAP) therapy changes the complexity of…
- Trial name
- EPPOSA (NCT07406620)
- Testing
- Continuous Positive Airway Pressure Therapy
- Where
- 2 sites in United Kingdom
- Volunteers
- 56 people
- Sponsor
- King's College London
Lung Diseases
Breath Analysis by Ion Mobility Spectrometry
Recognition of disease specific clusters of volatile organic compounds in patients with different lung diseases, using breath analysis with ion mobility spectrometry.
- Trial name
- NCT00632307
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Lung Clinic Hemer
Subjective Tinnitus, Sleep Disorder
Effects of Music Combined With CBT on Chronic Subjective Tinnitus
This study retrospectively analyzed the first and second visit data of chronic subjective tinnitus patients who received music combined with cognitive behavioral therapy in our hospital in recent years.
- Trial name
- NCT06505473
- Testing
- music-CBT
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Sleep Apnea Syndromes
Apnoea-Hypopnoea-Indices Determined Via Continuous Positive Airway Pressure vs Those Determined by Polysomnography
To date, no published systematic review and meta-analysis has compared AHI-CPAPflow and AHI-PSGgold. Therefore, the primary objective of this study is to compare published data for AHI-PSGgold and AHI-CPAPflow in patients treated…
- Trial name
- Meta IAHflow (NCT04526366)
- Testing
- Continuous Positive Airway Pressure, Polysomnography
- Where
- France
- Volunteers
- 1 people
- Sponsor
- University Hospital, Montpellier
Sleep Disorders, Circadian Rhythm
Actigraphic Measurement of a Neurosurgical Procedure
The study examines and illustrates the utility of utilizing actigraphic measurements to assess treatment response.
- Conditions
- Sleep Disorders, Circadian Rhythm, Pain, Rehabilitation
- Trial name
- NCT00945230
- Testing
- Re-section of a large left anterior cranial fossa meningioma
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Child Psychopharmacology Institute
Human Sleep and Chronobiology
Influence of Light on Sleep, Awakening, Electroencephalogram (EEG) and Cognitive Performances
The purpose of this project is to study the influence of light on sleep, wakefulness, EEG activity and cognitive performances. The study aim also to evaluate techniques for registration and analysis of the EEG over periods of…
- Trial name
- CHRONOSOMNO (NCT02858765)
- Testing
- Application of white polychromatic light for 2h30 at different times of day
- Where
- France
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Primary Insomnia, Sleep Initiation and Maintenance Disorders
Testing the Nocturnal Sleep Latency Profile in Primary Insomnia
This study tests a new kind of sleep study in which subjects are awakened 2 times after initially going to sleep. The study focuses on the EEG signal process as a person goes to sleep.
- Trial name
- NCT00167375
- Testing
- eszopiclone 3 mg qHS, General cognitive/behavioral interventions for insomnia
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Sleep Apnea Syndromes
Screening of Sleep Apnea by Holter Electrocardiography: Validation of Heart Rate Variability Analysis Algorithm
Obstructive sleep apnea syndrome (OSAS) is a growing health concern affecting up to 60 % of population with cardiovascular disease.
- Trial name
- NCT05435001
- Testing
- Holter ECG Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people
- Sponsor
- Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital
Tooth Eruption Disorder
Effects of a Gum Gel Intended to Treat Signs and Symptoms of Teething
Teething discomfort is a widespread disorder affecting a very high percentage of infants. The use of hyaluronic acid gels has been shown in the last 20 years to be an effective tool, generally devoid of side effects, in reducing…
- Trial name
- NCT04879836
- Testing
- Teething Gel, Teething Ring
- Where
- Italy
- Volunteers
- 51 people
- Sponsor
- University of Urbino "Carlo Bo"
Obstructive Sleep Apnea
A Pilot Study of Biomarkers in Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is common and is a risk factor for postoperative complications, including respiratory and cardiac events and delirium.
- Trial name
- Cytokine OSA (NCT02325687)
- Testing
- Lumbar Puncture (Standard-of-Care)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Hospital for Special Surgery, New York
Stroke, Hypertension
DELPHI in Subjects at Risk for Stroke and Dementia
The DELPhi system is a software device that is used for the noninvasive evaluation of brain plasticity and connectivity. The DELPhi software uses EEG and TMS devices as accessories.
- Conditions
- Stroke, Hypertension, Diabete Mellitus, Dyslipidemias
- Trial name
- NCT03884647
- Testing
- DELPhI system
- Where
- 4 sites in United States, Israel
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- QuantalX Neuroscience
Obstructive Sleep Apnea Syndrome
Air Leakage Under Continuous Positive Airway Pressure
The software embedded in recent continuous positive pressure devices enables the analysis of the level of leakage that occurs during treatment around the mask or from the mouth.
- Trial name
- SAS-leak-1 (NCT03381508)
- Testing
- Brizzy continuous positive pressure device
- Where
- 3 sites in France
- Volunteers
- 79 people
- Sponsor
- University Hospital, Montpellier
Obesity Hypoventilation Syndrome, Obstructive Sleep Apnea
Medico-economics and QoL of Obese Patients Followed by Medical Analysis Laboratories (BIOSAOS )
Obesity is a major risk factor for obstructive sleep apnea (OSA). However, OSA is still largely under diagnosed in patients with a high cardiovascular risk.
- Trial name
- BIOSAOS (NCT03861468)
- Testing
- Care pathway
- Where
- France
- Sponsor
- University Hospital, Grenoble