Clinical trials: Sleeve Gastrectomy
Obesity, Morbid
Banded Sleeve Gastrectomy Improves Weight Loss Compared to Non-banded Sleeve: Mid-term Results
Weight regain after Laparoscopic Sleeve Gastrectomy (LSG) is nowadays a growing concern. Sleeve dilatation and loss of food restriction is considered the main mechanism.
- Trial name
- NCT04228185
- Testing
- sleeve gastrectomy
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Rome Tor Vergata
Morbid Obesity Requiring Bariatric Surgery
Relationship Between Serum Resistin Levels and Reduction in Visceral Fat in Patients Undergoing Sleeve Gastrectomy Due to Morbid Obesity
This study aims to investigate whether a specific protein in the blood, called resistin, can help doctors predict how much dangerous internal fat a patient will lose following weight loss surgery.
- Trial name
- NCT07564986
- Testing
- Laparoscopic Sleeve Gastrectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sercan YUKSEL, MD
Intra-Operative Injury - Other, Post Operative Hemorrhage
Preoperative Hexakapron Reduces Bleeding in Bariatric Surgery
Prophylactic use of tranexamic acid to reduce intra and postoperative bleeding in primary sleeve gastrectomy procedures will be studied.
- Conditions
- Intra-Operative Injury - Other, Post Operative Hemorrhage, Tranexamic Acid
- Trial name
- PHORBBS (NCT03085394)
- Testing
- tranexamic acid
- Where
- Israel
- Volunteers
- 152 people
- Sponsor
- Sheba Medical Center
Obesity, Morbid, Transplant; Failure, Kidney
Effect of Laparoscopic Sleeve Gastrectomy in the Morbidly Obese, Kidney Transplant Candidate
A prospective clinical trial will study the effects of laparoscopic sleeve gastrectomy in the potential renal transplant candidate who is denied acceptance due mainly to the morbid obesity.
- Trial name
- NCT01913392
- Testing
- laparoscopic sleeve gastrectomy
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Obesity, Morbid, Bariatric Surgery (Sleeve Gastrectomy )
Flow-Controlled vs Volume-Controlled Ventilation in Morbidly Obese Patients Undergoing Laparoscopic Bariatric Surgery
The goal of this clinical trial is to compare the effects of flow-controlled ventilation (FCV) and volume-controlled ventilation (VCV) on hemodynamic and respiratory parameters in obese patients undergoing elective laparoscopic…
- Conditions
- Obesity, Morbid, Bariatric Surgery (Sleeve Gastrectomy ), Mechanical Ventilation
- Trial name
- NCT07641829
- Testing
- Flow-Controlled Ventilation (FCV), Volume-Controlled Ventilation (VCV)
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Ankara Training and Research Hospital
Diabetes Mellitus Type 2 in Obese
Randomized Comparative Study of Sleeve Gastrectomy Versus MGB and SASI Bypass , Randomized Study
the investigator Randomized and compare the efficacy of 3 types of metabolic surgery in the treatment of type 2 diabetes in obese patients, one of them is SASI bypass which is a modification of Santoro's operation by performing a…
- Trial name
- NCT03394157
- Testing
- metabolic surgery
- Volunteers
- 800 people
- Sponsor
- tarek mahdy
Morbid Obesity, Metabolic Syndrome
The S.L.I.M.M.S. Procedure for Severe Clinical Obesity
Assessment of Gastric Bypass combined with Vertical Sleeve Gastrectomy as primary treatment for patients with severe clinical obesity.
- Conditions
- Morbid Obesity, Metabolic Syndrome, Type2 Diabetes, Insulin Resistance
- Trial name
- SLIMMS (NCT04592601)
- Testing
- S.L.I.M.M.S. Procedure
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- The N.E.W. Program
Bariatric Surgery Candidate, Postoperative Nausea and Vomiting
Prevention of Postoperative Nausea and Vomiting After Bariatric Surgery
Postoperative nausea and vomiting are common occurrences following bariatric surgery, occurring in up to 80% of patients and contributing to increased healthcare utilization and delays in discharge.
- Conditions
- Bariatric Surgery Candidate, Postoperative Nausea and Vomiting, Morbid Obesity
- Trial name
- NCT04644445
- Testing
- Bariatric Full Liquid Diet
- Where
- 2 sites in United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Severe Obesity
Bypass Equipoise Sleeve Trial (BEST)
This is nationwide registry-based randomised clinical multicenter trial in which patients will be randomised to gastric bypass (RYGB) or sleeve gastrectomy (SG).
- Trial name
- BEST (NCT02767505)
- Testing
- gastric bypass, Sleeve gastrectomy
- Where
- 21 sites in Norway, Sweden
- Volunteers
- 1,752 people
- Sponsor
- Göteborg University
Morbid Obesity
Comparison of Stapled and Hand-Sewn Sleeve Gastrectomy
Sleeve gastrectomy is a stapler dependent bariatric procedure. A hand-sewn sleeve gastrectomy can be necessary under certain circumstances.
- Trial name
- NCT03982823
- Testing
- Hand-Sewn Sleeve Gastrectomy, Stapled Sleeve Gastrectomy
- Volunteers
- 13 people
- Sponsor
- Inonu University
Anesthesia, Total Intravenous Anesthesia
The Effect of Anesthetic Methods on Gastrointestinal Motility
The goal of this randomized controlled single blinded study is to compare the effect of the type of anesthesia on gastrointestinal motility in patients scheduled for laparoscopic sleeve gastrectomy.
- Trial name
- NCT05951686
- Testing
- Desflurane, Remifentanil infusion, Fresh gas
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Bozyaka Training and Research Hospital
GERD, Bariatric Surgery
Endoscopic Cardiac Band Ligation for the Management of Refractory GERD After Laparoscopic Sleeve Gastrectomy
GERD is a prevalent condition worldwide, estimated to be around 20-30 % in North America. Obesity is rapidly increasing with an estimated prevalence of 66% in the adult population in the United States.
- Conditions
- GERD, Bariatric Surgery, Laparoscopic Sleeve Gastrectomy
- Trial name
- CLEAR (NCT04771247)
- Testing
- Cardia Band Ligation
- Sponsor
- Johns Hopkins University
Bariatric Surgery Candidate
Pharmacokinetics and Pharmacodynamics of Edoxaban Before and After Bariatric Surgery
The study will be conducted at a single site in the Canada, Quebec. Participants will be recruited from the bariatric surgery clinic and will be required to be either, waiting for sleeve gastrectomy surgery (n=12, restrictive…
- Trial name
- EXPOSE (NCT06326138)
- Testing
- Edoxaban Pharmacokinetics and Pharmacodynamics
- Sponsor
- Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
Gastroesophageal Reflux Disease (GERD)
One-year Clinical Outcomes of Endoscopic Cardia Banding Plication for Refractory Gastroesophageal Reflux Disease After Laparoscopic Sleeve Gastrectomy
This single-center retrospective cohort study was conducted at the Center for Bariatric and Metabolic Surgery, China-Japan Friendship Hospital, Beijing, China, and is reported in accordance with the STROBE guidelines for…
- Trial name
- NCT07749352
- Testing
- endoscopic cardia banding plication
- Where
- China
- Volunteers
- 47 people
- Sponsor
- China-Japan Friendship Hospital
Obesity, Morbid, Obesity and Overweight
Identification of Pre-surgical Phenotypic Indicators Predictive of Quality of Life Trajectories in Obese Patients Following Bariatric Surgery
This study aims to identify pre-operative phenotypic determinants predictive of quality of life trajectories in post-bariatric surgery patients.
- Conditions
- Obesity, Morbid, Obesity and Overweight, Bariatric Surgery, Bariatric Surgery Patients
- Trial name
- PHENOBEQOL73 (NCT06951893)
- Testing
- Hospital Anxiety and Depression Scale, Dutch Eating Behaviour Questionnary, Impact of Weight on Quality Of Life
- Where
- France
- Volunteers
- 165 people
- Sponsor
- Centre Hospitalier Metropole Savoie
Diaphragmatic Dysfunction
Erector Spinae Plane Block and Its Impact on Postoperative Diaphragmatic Dysfunction in Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy
postoperative diaphragmatic dysfunction is critical especially in morbidly obese patients
- Trial name
- NCT07022600
- Testing
- Diaphragmatic ultrasound
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Obesity
Remote Intervention for Weight Regain After Sleeve Gastrectomy
The study is designed to assess the effect of a 3-month remote comprehensive intervention program by a multidisciplinary team combined with mobile supportive text messages aimed to raise the level of happiness and subjective…
- Trial name
- NCT05122013
- Testing
- A comprehensive remote multidisciplinary intervention for weight regain after sleeve gastrectomy, Control group
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assuta Medical Center
Gastroesophageal Reflux
ARMA for Postoperative GERD After Sleeve Gastrectomy
This study is a pilot trial designed to evaluate the safety and efficacy of endoscopic anti-reflux ablation in postoperative gastroesophageal reflux after sleeve gastrectomy
- Trial name
- NCT05259579
- Testing
- Anti-reflux mucosal ablation
- Where
- Hong Kong
- Volunteers
- 15 people
- Sponsor
- Chinese University of Hong Kong
Type 2 Diabetes Mellitus
Early Sleeve Gastrectomy In New Onset Diabetic Obese Patients
Bariatric surgery is efficient in both inducing adequate weight loss and the control of glycemia in obese patients affected by Type 2 Diabetes Mellitus (T2DM).
- Trial name
- ESINODOP (NCT02488733)
- Testing
- LSG, CMT
- Where
- 2 sites in Italy
- Volunteers
- 30 people
- Sponsor
- Azienda Ospedaliera Santa Maria, Terni, Italy
Obesity and Obesity-related Medical Conditions
Management of Obese Patients With Gastroesophageal Reflux Disease .
The aim of this study is to evaluate the efficacy Sleeve gastrectomy with cruroplasty with or without ligamentum teres wrapping for management of morbidly obese patients with concomitant reflux symptoms.
- Trial name
- NCT06599489
- Testing
- surgery ..operation
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hossam Mahmoud Ibrahim