Clinical trials: Slow Breathing
Chest Wall Disorder, Neuromuscular Disease
AutoVPAP Versus VPAP; Assessment of Sleep and Ventilation
The aim of the study is to compare the effects of a modified form (AutoVPAP) of the VPAP non-invasive ventilator versus standard VPAP ventilation on sleep quality and breathing during sleep in stable patients with nocturnal…
- Trial name
- NCT00252252
- Testing
- VPAP non-invasive ventilator, AutoVPAP non-invasive ventilator
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- ResMed
Neuromuscular Disease
Prevalence of Nocturnal Hypoventilation in Neuromuscular Diseases According to Different Definitions
Different definitions of nocturnal hypoventilation are used in the recent literature. The investigators aimed to compare the prevalence of nocturnal hypoventilation in a neuromuscular disease's population according to different…
- Trial name
- TcCO2 (NCT02356666)
- Where
- France
- Volunteers
- 232 people
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Hypoventilation, Hyperventilation
Investigating the Effect of Yoga-based Breathing Styles on the Human Brain, With a Focus on Memory
The goal of this clinical trial is to learn if yoga-based breathing styles could improve memory performance in adult persons without relevant prior experience in yoga, meditation or similar disciplines and without existing health…
- Trial name
- NCT05846425
- Testing
- Nose-breathing training, Mouth-breathing training
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universität des Saarlandes
Chronic Hypercapnic Respiratory Failure, Obesity Hypoventilation Syndrome
Patient -Ventilator Interaction in Chronic Respiratory Failure
To evaluate a novel advanced physiological monitoring system to improve nocturnal non-invasive ventilation (NIV) in Neuromuscular disease (NMD), Chest wall disease (CWD), Chronic Obstructive Pulmonary Disease (COPD) and Obesity…
- Conditions
- Chronic Hypercapnic Respiratory Failure, Obesity Hypoventilation Syndrome, Neuromuscular Disease, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT01371149
- Testing
- Surface parasternal electromyography (EMG) set up
- Where
- 2 sites in United Kingdom
- Volunteers
- 58 people
- Sponsor
- Michelle Ramsay
Obstructive Sleep Apnea, HIV/AIDS
The Pathogenesis of OSA in People Living With HIV
The purpose of this study is to help us understand how HIV and/or Anti-Retroviral Therapy (ART) may predispose individuals to Obstructive Sleep Apnea (OSA). The traditional risk factors for OSA are weight and age.
- Trial name
- NCT03064204
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH)
The Effect of Slow-Paced Breathing on Patient Outcomes in Pulmonary Arterial Hypertension
This study aims to investigate the effects of slow-paced breathing (SPB) intervention applied to patients with pulmonary arterial hypertension (PAH) in the home environment on symptom management (dyspnea, fatigue, sleep quality)…
- Trial name
- NCT07232368
- Testing
- Slow-paced breathing intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Ege University
Obesity Hypoventilation Syndrome
Prevalence Rate, and Clinical Characteristics of Obesity Hypoventilation Syndrome Via Screening Patients Admitted to Medical Intensive Care Units
A prospective observation study to screen adult obese (BMI ≥30 kg/m2) patients who were newly admitted to the medical intensive care units and turned out to be diagnosed as Obesity hypoventilation syndrome(OHS).
- Trial name
- NCT02934581
- Where
- Taiwan
- Volunteers
- 52 people
- Sponsor
- National Taiwan University Hospital
Cystic Fibrosis
Sleep in Patients With Cystic Fibrosis
The aim of the study is to identify the parameters that are associated with nocturnal hypoventilation in children and adults with cystic fibrosis.
- Trial name
- Sommeil (NCT00804661)
- Testing
- SENTEC device
- Where
- France
- Volunteers
- 76 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Heart Diseases
The Precision of Pulmonary Artery Cardiac Output-measurements in Spontaneously Breathing Patients
The intention of this study is to determine whether the precision of the measure of cardiac output can be optimized by conducting the measurement while the participant is instructed to exhale slowly.
- Trial name
- TEMP2 (NCT01944254)
- Testing
- Cardiac output measurement at random to respiration, Cardiac output measurement synchronised at start of expiration, Cardiac output measurement timed to instructed exhalation
- Where
- Norway
- Volunteers
- 18 people
- Sponsor
- Norwegian University of Science and Technology
Autonomic Nervous System
Acute Effects of Deep-Slow Breathing Exercise and Cranial-Visceral Manual Therapy on ANS Parameters in Healthy Adults
The purpose of this study is to evaluate the effects of several manual therapy techniques on autonomic nervous system and to compare it with other groups in the study such as deep-slow breathing group and the control group.
- Trial name
- NCT05084313
- Testing
- Manual Therapy, Deep-slow breathing, Control
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ege University
Hypoventilation, Hypoxia
Using Capnography to Reduce Hypoxia During Pediatric Sedation
The investigators hypothesize that the addition of capnography during moderate sedation will improve recognition of hypoventilation and apnea.
- Trial name
- NCT01463527
- Testing
- Nellcor NPB-70 Capnograph
- Where
- United States
- Volunteers
- 167 people
- Sponsor
- Yale University
Type II Respiratory Failure, Hypercapnic Respiratory Failure
Post-Extubation High-Flow Nasal Cannula Versus Non-Invasive Ventilation in Type II Respiratory Failure
Acute hypercapnic respiratory failure is characterized by elevated arterial carbon dioxide levels and commonly occurs in patients with chronic respiratory diseases.
- Trial name
- NCT06918288
- Testing
- High-Flow Nasal Cannula (HFNC), Non-Invasive Ventilation (NIV)
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Benha University
Diaphragm Pacing
Effects of Combined Thoracic and Diaphragmatic Breathing on Cognitive and Psycho-Physiological Functions
This study aims to investigate the effects of a combined thoracic expansion exercise (TEE) and slow diaphragmatic breathing (SDB) program on cognitive function, brain activation, psychological status, and head-shoulder posture in…
- Trial name
- NCT07620249
- Testing
- thoracic expansion exercises and slow diaphragmatic breathing
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Clinical Trial Center
Obstructive Sleep Apnea, Obesity Hypoventilation Syndrome
Postoperative Complications in Patients With Obesity Hypoventilation Syndrome
Obstructive sleep apnea (OSA) and Obesity-Hypoventilation Syndrome (OHS) are common conditions in obesity, which may influence the prognosis in patients undergoing surgery.
- Conditions
- Obstructive Sleep Apnea, Obesity Hypoventilation Syndrome, Hypercapnia, Post-Op Complication
- Trial name
- OHBE (NCT02980770)
- Where
- Turkey (Türkiye)
- Volunteers
- 999 people
- Sponsor
- Marmara University
Slow Breathing
Assessing the Acute Effects of Virtual Reality Interventions on Stress
A Four-Arm RCT, testing the acute effects of a Virtual Reality (VR)- based slow-paced breathing intervention on subjective and physiological markers of stress.
- Trial name
- VR_Stress_25 (NCT07191288)
- Testing
- VR (VR-Breathing+Mystical), VR (VR-Mystical), Computer (Non-VR-Breathing)
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Prof. Dominique de Quervain, MD
Post-extubation Failure, Persistent Weaning Failure
Effects of Mechanical Insufflation-Exsufflation in Preventing Respiratory Failure After Extubation
Weaning protocols that include the use of noninvasive ventilation (NIV), decreases the incidence of re-intubation and ICU length of stay. However, the role of NIV in post-extubation failure is still not clear.
- Conditions
- Post-extubation Failure, Persistent Weaning Failure, Secretion Encumbrance, Weak Cough
- Trial name
- MIEICU (NCT01424202)
- Testing
- Mechanical Insufflation Exsufflation
- Where
- Portugal
- Volunteers
- 92 people
- Sponsor
- Hospital Sao Joao
Obesity Hypoventilation Syndrome
Obesity Hypoventilation Syndrome Prevalence Study
This is an observational study to characterize the prevalence of Obesity Hypoventilation Syndrome in patients referred to the sleep lab.
- Trial name
- NCT01964339
- Testing
- BMI greater than or equal to 30kg/m2 scheduled for PSG. Undergo blood draw (venous blood gas and metabolic panel) and data collection from PSG study., BMI greater than or equal to 30kg/m2 scheduled for PSG. Undergo blood draw (arterial blood gas and metabolic panel) and data collection from PSG study.
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Philips Respironics
Ventilatory Failure
Comparison of Two Different NCPAP Methods in Preterm Infants With Respiratory Distress Syndrome
is to compare introduction of two different NCPAP methods in terms of mechanical ventilation (MV) need (non-invasive respiratory support failure) and surfactant need within the first 72 hours of life in preterm infants with…
- Trial name
- (NCPAP) (NCT03400670)
- Testing
- ventilator NCPAP
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Anesthesia, Hypoventilation
Opioid-sparing Versus Sevoflurane Anesthesia on Early Postoperative Hypoventilation in Laparoscopic Bariatric Surgery
Determine the incidence of early post-operative hypoventilation in post-anesthesia care unit (PACU) in patients undergoing laparoscopic bariatric surgery under opioid-sparing compared with sevoflurane-based anesthesia.
- Conditions
- Anesthesia, Hypoventilation, Opioid Use, Bariatric Surgery
- Trial name
- NCT05962671
- Testing
- Opioid-sparing based anesthesia, Sevoflurane-based anesthesia
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Tanta University
Ondine Syndrome, Congenital Central Hypoventilation Syndrome (CCHS)
Relationship Between Breathing and Attention in Children With Ondine Syndrome
Congenital central hypoventilation syndrome (CCHS) is a rare disorder of autonomic and respiratory regulation that alters oxygen delivery to the brain. CCHS patients are at risk for broad neurocognitive deficits.
- Trial name
- OndineCo (NCT06337149)
- Testing
- neuropsychological tests used usually in clinical practice (TEA-ch, NEPSY, BRIEF) and research (Conners 3, K-CPT II or CPT III, Flankers Task)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris