Clinical trials: Slow Breathing
Normobaric Hypoxia, Hypoventilation
"Living Low - Training High" Methods and Physiological Responses in Well-trained Swimmers
To overcome the lack of knowledge regarding the impact of different "living low, training high" methods on swimming performance, a 4-week intervention will be carried out to determine and compare the effects of three Repeated…
- Conditions
- Normobaric Hypoxia, Hypoventilation, Normoxia
- Trial name
- NCT06253039
- Testing
- Repeated sprint
- Where
- Portugal
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Hypoventilation, Hypoxemia
Oxygen Supplementation and Ventilator Hyperinflation in the Endotracheal Suction (OSVHES)
This is a double crossover study where all patients are randomly allocated to one of two treatment sequences associated with endotracheal aspiration.The first treatment (A) uses two suctioning methods for each patient: one…
- Trial name
- OSVHES (NCT02440919)
- Testing
- Hyperoxygenation 100% FiO2, Hyperoxygenation 20% FiO2, Hyperinflation (PEEP- ZEEP) Basal FiO2
- Where
- Brazil
- Volunteers
- 78 people
- Sponsor
- Universidade Federal de Sao Carlos
Healthy Volunteers
Effects of Breath-Hold vs Standard Interval Training on Fitness in Mountaineers
This study investigated whether adding structured breath-holds to standard interval training improves cardiorespiratory fitness in recreational mountaineers more than interval training alone.
- Trial name
- NCT07703839
- Testing
- Voluntary Hypoventilation Training, Progressive Treadmill Interval Training
- Where
- Iran
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mohammadreza Rezaeipour, MD, PhD
Nocturnal Hypoventilation, Obesity
Prevalence of Nocturnal Hypoventilation in Obese Subjects Fiited With Continuous Positive Airway Pressure for Obstructive Sleep Apnea / Hypopnea Syndrome
CAPNOSOH study is a single-center study conducted at Toulouse University Hospital, aiming to estimate the prevalence of obese and apneic subjects maintaining nocturnal hypoventilation under continuous positive airway pressure…
- Conditions
- Nocturnal Hypoventilation, Obesity, Sleep Apnea Hypopnea Syndrome
- Trial name
- CAPNOSOH (NCT07152990)
- Testing
- Transcutaneous Oxy-Capnography, Quality of life questionnaires, Arterial gasometry
- Where
- France
- Volunteers
- 139 people
- Sponsor
- University Hospital, Toulouse
Obesity Hypoventilation Syndrome (OHS)
HVNI Versus NIV In Management Of Acute Hypercapnic Respiratory Failure In OHS
1. Assessment of benefits of HVNI in management of obesity hypoventilation syndrome complicated with acute hypercapnic respiratory failure. 2.
- Trial name
- NCT05805293
- Testing
- High-Velocity Nasal Insufflation Therapy, Non-Invasive Ventilation
- Volunteers
- 56 people
- Sponsor
- Assiut University
Chronic Obstructive Pulmonary Disease
Comparative Effects of ACBT and Slow Expiration in Patients With Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is characterized by nonreversible airway obstruction. A diagnosis of COPD is determined by clinical assessment of airflow limitation and symptoms such as cough and wheeze; however, the…
- Trial name
- NCT05922267
- Testing
- ACTIVE CYCLE OF BREATHING TECHNIQUES, SLOW EXPIRATION WITH OPEN GLOTTIS IN LATERAL POSITION
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Cardiac Arrest, Trauma
Pre-Hospital Advanced Airway Management in the Nordic Countries
Pre-Hospital Advanced Airway Management (PHAAM) is a potentially lifesaving intervention. A recent Danish multicentre single country study demonstrated a 99,7% incidence of successful anaesthesiologist pre-hospital endotracheal…
- Conditions
- Cardiac Arrest, Trauma, Traumatic Brain Injury, Hypoventilation
- Trial name
- PHAST (NCT02450071)
- Where
- Sweden
- Volunteers
- 2,028 people
- Sponsor
- Karolinska Institutet
Medical Complication
Postoperative Opioid and Respiratory Depression in Opioid Naive and Chronic Opioid Patients
Aim: To describe the duration of desaturation and bradypnea in postoperative opioid-naïve and chronic opioid patients. Patients: 691 patients included from two previous WARD (Wireless Assessment of Respiratory and circulatory…
- Trial name
- NCT06227208
- Testing
- Continuous vital sign monitoring
- Where
- 2 sites in Denmark
- Volunteers
- 691 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Critical Illness, Hyperglycemia
Effects of a Complete Diet in Critically Ill Patients With Stress Hyperglycemia
The aim of the study is to evaluate the beneficial effects of the administration of a complete diet rich in monounsaturated fatty acids (MUFA) and slow absorption carbohydrate in patients with stress hyperglycemia(T-Diet Plus…
- Conditions
- Critical Illness, Hyperglycemia, Dietary Modification, Metabolic Stress Hyperglycemia
- Trial name
- NCT01233726
- Testing
- T-Diet plus Diabet IR, ISOSOURCE PROTEIN FIBRE, GLUCERNA SELECT
- Where
- 2 sites in Spain
- Volunteers
- 159 people
- Sponsor
- Vegenat, S.A.
Pulmonary Arterial Hypertension
Feasibility of Slow-paced Respiration Therapy for Treatment of a Symptom Cluster in Pulmonary Arterial Hypertension
Pulmonary arterial hypertension (PAH) is a chronic illness characterized by increased pulmonary pressures resulting in right heart failure and premature death.
- Trial name
- NCT02080533
- Testing
- Slow-paced respiration therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Pennsylvania
Obesity, Pulmonary Atelectasis
Effects of PEEP on Heart and Lungs in Obese Subjects
Aim of this study is to better understand pathophysiology of the alteration of respiratory mechanics and cardiovascular function in obese volunteer subjects.
- Conditions
- Obesity, Pulmonary Atelectasis, Obesity Hypoventilation Syndrome, Magnetic Resonance Imaging
- Trial name
- NCT02523352
- Testing
- Non-Invasive Ventilation, Esophageal catheter positioning
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Hypoventilation
Respiratory Consequences of N95-type Mask Usage in Pregnant Healthcare Workers - A Controlled Clinical Study
The study aims to find out if usage of N95 type respirators affects respiratory parameters in pregnant women so as to provide guidance on N95 respirator usage in pregnant healthcare workers.
- Trial name
- NCT02265926
- Testing
- N95 mask
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- National University Health System, Singapore
Obesity Hypoventilation Syndrome (OHS)
Evaluation of Upper Extremity Functions in Obesity Hypoventilation Syndrome Patients
Obesity Hypoventilation Syndrome (OHS) is a disease characterized by daytime hypercapnia and sleep-related respiratory disturbances in individuals with a body mass index (BMI) greater than 30 kg/m², without any other condition…
- Trial name
- NCT06766110
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Istanbul University - Cerrahpasa
Sleep Apnea, Obstructive, Obesity Hypoventilation Syndrome
Treatment for Obstructive Sleep Apnea Hypopnea Syndrome and Obesity Hypoventilation Syndrome (OHS)
Sleep Apnea Hypopnea Syndrome (OSAHS), is common in patients with OHS, compared to single Obesity Hypoventilation Syndrome (OHS) or OSAHS ,patients with both of them are more susceptible to have serious hypoxia and carbon dioxide…
- Trial name
- NCT01553227
- Testing
- ventilator
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Nanjing Medical University
Multiple Myeloma, Breathing Techniques
Effects of Controlled Breathing Added to Therapeutic Exercise in Multiple Myeloma
A randomized, parallel, double-blind, controlled, multicenter clinical trial with two intervention arms. Two groups of participants will be included, both receiving a therapeutic exercise intervention and an educational session…
- Conditions
- Multiple Myeloma, Breathing Techniques, Breathing Exercises, Exercise Activity
- Trial name
- NCT07312942
- Testing
- Controlled breathing exercise protocol + therapeutic exercise + initial education session, Therapeutic exercise + initial education session
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Universidad Complutense de Madrid
Acute Mechanical Ventilatory Failure
Weaning From Prolonged Mechanical Ventilation
Patients requiring the use of artificial ventilation (also called mechanical ventilation) for more than 21 days account for more than 37% of all ICU costs.
- Trial name
- NCT01541462
- Testing
- Weaning
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- RML Specialty Hospital
Malignant Neoplasm
Meditative Slow Breathing or Isha Kriya Meditation in Improving Cancer-Related Symptoms in Hospitalized Participants With Cancer
This trial studies how well meditative slow breathing or Isha Kriya meditation works in improving cancer-related symptoms in hospitalized participants with cancer.
- Trial name
- NCT03445572
- Testing
- Best Practice, Meditation Therapy, Questionnaire Administration
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- M.D. Anderson Cancer Center
Respiratory Failure With Hypercapnia, Therapeutic Bronchofiberoscopy
To Assess the Types of Mechanical Ventilation in Enabling Therapeutic Bronchofiberoscopy in Patients With Decompensated Respiratory Acidosis (Complete Respiratory Failure).
Background: Bronchofiberoscopy (FOB) is a minimally invasive and safe procedure performed for diagnostic and therapeutic purposes.
- Trial name
- NCT06970041
- Testing
- Use of NIV during therapeutic FOB as a respiratory support method in patients with type 2 respiratory failure, Use of HFNC during therapeutic FOB as a respiratory support method in patients with type 2 respiratory failure
- Volunteers
- 315 people
- Sponsor
- Medical University of Silesia
Hypotension, Consciousness, Level Altered
The Effect of phoSPHocreatine on mEdical Emergency Team (Met) tREated Patients
Unexpected deaths and unplanned intensive care unit (ICU) admissions are common during hospital stay and are often preceded by warning abnormalities in patients' vital signs.
- Conditions
- Hypotension, Consciousness, Level Altered, Airway Disease, Respiratory Failure
- Trial name
- SPHERE (NCT06503016)
- Testing
- Phosphocreatine
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Università Vita-Salute San Raffaele
Alveolar Hypoventilation Resulting in Hypoxemia
Capnography During Nurse Administered Propofol Sedation
Rationale: The current standard of respiratory monitoring for patients during deep sedation is continuous pulse oximetry with visual assessment of the patient.
- Trial name
- NCT01220765
- Testing
- Capnography
- Where
- Netherlands
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht