Clinical trials: Small Bowel Obstruction
Small Bowel Obstruction, Intestinal Obstruction and Ileus
The Effect of Nasogastric Tube Placement on Complications in Patients With Small Bowel Obstruction - the SBO-TUBE Trial
Background: Small bowel obstruction (SBO) is a surgical emergency where the normal continuous bowel movements are hindered and approximately 8000-9000 patients visit the emergency department every year in Sweden due to SBO.
- Trial name
- SBO-TUBE (NCT07574515)
- Testing
- Nasogastric tube placement
- Where
- 3 sites in Sweden
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Linkoeping
Small Bowel Obstruction, Quality of Life
The Impact of Small Bowel Obstruction (SBO) on Quality of Life (QOL)
This study has two segments the first is a chart and outcome assessment of patients treated at Clear Passage (CP) with a history of small bowel obstruction (SBO).
- Conditions
- Small Bowel Obstruction, Quality of Life, Bowel Obstruction
- Trial name
- NCT02639195
- Testing
- Treatment
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Clear Passage Therapies, Inc
Acute Appendicitis, Perforated Gastroduodenal Ulcer
Antibiotic Prophylaxis in the Prevention of Surgical Site Infections After Selected Urgent Abdominal Surgical Procedures
Aim of prospective randomized a placebo controlled study is to prove that in case of acute surgical procedure due to appendicitis, ileus of small bowel and perforation of small bowel and stomach appropriately administered…
- Conditions
- Acute Appendicitis, Perforated Gastroduodenal Ulcer, Small Bowel Obstruction
- Trial name
- NCT01524081
- Testing
- Metronidazole, Cefuroxime, Amoxicillin (+ clavulanic acid) and Fluconazole
- Where
- Czechia
- Volunteers
- 187 people
- Sponsor
- The Faculty Hospital Na Bulovce
Malignant Small Bowel Obstruction, Malignant Gastric Outlet Obstruction
AspireAssist for Palliative Venting Gastrostomy in Malignant Bowel Obstruction Patients
Individuals with cancer causing an intestinal or stomach obstruction often require gastric drainage to prevent symptoms of nausea, vomiting, and to prevent aspiration.
- Trial name
- NCT04375462
- Testing
- AspireAssist device, Standard decompressive PEG tube, gastric outlet obstruction scoring system (GOOSS) questionnaire
- Where
- United States
- Sponsor
- Case Comprehensive Cancer Center
Adhesive Small Intestine Obstruction
(Gastrografin Use in Small Bowel Obstruction Caused by Adherences)
Adhesive small intestine obstruction (ASIO) is an important cause of hospital admission and a very common disease. Any improvement in this field will benefit many patients by reducing the operative rate.
- Trial name
- GUSBOCA (NCT00601809)
- Testing
- traditional conservative treatment (TT), Gastrografin®: G
- Where
- 2 sites in Italy
- Volunteers
- 76 people
- Sponsor
- University of Bologna
The Prevalence of Surgery for Small Bowel Obstruction After LGBP Procedure.
Internal Hernia After Laparoscopic Gastric Bypass
To see if closing the mesenteric defects created at a Laparoscopic Gastric Bypass is better than leaving them open.
- Trial name
- NCT01137201
- Testing
- Suturing of mesenteric defects
- Where
- Sweden
- Volunteers
- 2,507 people
- Sponsor
- Region Örebro County
Small Bowel Obstruction
A Procalcitonin-based Algorithm in Adhesion-related Small Bowel Obstruction
Adhesion-related small bowel obstruction is a common digestive emergency that can be managed either conservatively or surgically.
- Trial name
- ALPROC (NCT03905239)
- Testing
- algorithm
- Where
- France
- Volunteers
- 488 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Small Bowel Obstruction
REsectability Small Bowel Obstruction LAParoscopic (RESBOLAP) Score. Multicentric Data Registry
AIM OF THE STUDY The aim of the study is to develop a Resectability Laparoscopic Score as a helpful instrument during intraoperative decision-making in the setting of emergency laparoscopic surgery for small bowel obstruction…
- Trial name
- RESBOLAP (NCT05842135)
- Testing
- Laparoscopic approach to small bowel obstrcuction
- Where
- Italy
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- San Salvatore Hospital, AST Pesaro-Urbino
Colorectal Cancer, Constipation, Impaction, and Bowel Obstruction
Octreotide as Palliative Therapy for Cancer-Related Bowel Obstruction That Cannot Be Removed by Surgery
RATIONALE: Palliative therapy with octreotide may help patients who have bowel obstruction that cannot be removed by surgery to live longer and more comfortably.
- Conditions
- Colorectal Cancer, Constipation, Impaction, and Bowel Obstruction, Extrahepatic Bile Duct Cancer, Gastric Cancer
- Trial name
- NCT00004895
- Testing
- octreotide acetate
- Where
- United States
- Sponsor
- Northwestern University
Acute Small Intestine Obstruction
Small Bowel Obstruction and Surgery
Postoperative management after small bowel obstruction (SBO) surgery is not consensual and better knowledge of risk factors for postoperative morbidity could help to add evidence of the feasibility of enhanced recovery programs…
- Trial name
- NCT03826251
- Testing
- Nasogastric tube removal
- Volunteers
- 190 people
- Sponsor
- University Hospital, Angers
SBO - Small Bowel Obstruction
A Multicenter Retrospective Review of Management Strategies in Small Bowel Obstruction
The objective of the study is to review performance of water soluble contrast study in patients admitted with Small Bowel Obstruction(SBO), will improve quality and safety, and decrease length of stay and morbidity.
- Trial name
- NCT06223620
- Testing
- review performance of water soluble contrast
- Where
- United States
- Volunteers
- 504 people
- Sponsor
- Methodist Health System
Small Bowel Obstruction
Development and Validation of a CT-based Diagnostic Models Using Artificial Intelligence for Detection of Small Bowel Obstruction
Small bowel obstruction (SBO) is a common non-traumatic surgical emergency. All guidelines recommend computed tomography (CT) as the first-line imaging test for patients with suspected SBO.
- Trial name
- SMARTLOOP2 (NCT05566158)
- Where
- 2 sites in France
- Volunteers
- 8,000 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Small Bowel Obstruction
Point of Care Ultrasound for Suspected Small Bowel Obstruction in the Emergency Department
The primary purpose of this study is to determine the accuracy of ultrasound in diagnosing small bowel obstruction in emergency department patients, as compared to the criterion standards of computed tomography, operative…
- Trial name
- NCT02190981
- Testing
- Ultrasound for Small Bowel Obstruction
- Where
- 3 sites in United States
- Volunteers
- 217 people
- Sponsor
- WellSpan Health
Small Bowel Obstruction
Small Bowel Obstruction. A Prospective Multicener Study
To get an overview of patients hospitalized with mechanical small bowel obstruction and the evaluate the use of contrast media as part of conservative management.
- Trial name
- SBO (NCT05662384)
- Testing
- No intervention is planned
- Where
- Estonia
- Volunteers
- 214 people
- Sponsor
- University of Tartu
Gastric Cancer
Bioresorbable Membrane to Reduce Postoperative Small Bowel Obstruction
To assess whether the use of Seprafilm reduces the rate of small bowel obstruction in patients who underwent surgery for gastric cancer.
- Trial name
- NCT00529412
- Testing
- Seprafilm
- Where
- Japan
- Volunteers
- 150 people
- Sponsor
- Nihon University
Small Bowel Obstruction
Gastrografin for Treating Small Bowel Obstruction in Children
This is a multi-centre clustered open label clinical trial testing the effectiveness of adding Gastrografin to standard non-surgical management of small bowel obstruction.
- Trial name
- NCT03573921
- Testing
- Gastrografin, Saline solution (control treatment)
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Adhesive Small Bowel Obstruction
A Study of the Cost for Patients Operated for Adhesive Obstruction (SBO) During a Five-year Period
A cohort study of the cost for patients operated for adhesive small bowel obstruction (SBO) during a five-year period
- Trial name
- NCT03602352
- Volunteers
- 402 people
- Sponsor
- Uppsala University
Adhesive Small Bowel Obstruction
Optimizing Treatment of Adhesive Small Bowel Obstruction
Small bowel obstruction (SBO) is one of the most common causes of serious gastrointestinal disease in the US. Adhesion-related SBO (aSBO) is usually treated by the placement of a nasogastric tube (NGT) to decompress the stomach…
- Trial name
- NCT06182319
- Testing
- Gastrografin, Saline, SBO Treatment Without NG Tubes
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, Los Angeles
Chronic Intestinal Pseudo-obstruction
Efficacy and Safety of Rifaximin for Patients With Chronic Intestinal Pseudo-obstruction: a Phase 2 Trial
The objective of the study is to investigate efficacy and safety of rifaximin (L-105) in patients with chronic idiopathic intestinal pseudo-obstruction(CIIPO) or patients with chronic intestinal pseudo-obstruction (CIPO)…
- Trial name
- NCT04118699
- Testing
- Rifaximin oral tablet
- Where
- Japan
- Volunteers
- 12 people
- Sponsor
- Yokohama City University
Small Bowel Obstruction
Diagnostic Scoring for Small Bowel Obstruction
It is difficult to predict which patients with acute small bowel obstruction require operative intervention and which ones can be handled conservatively. Similarly, strangulation remains difficult decision.
- Trial name
- NCT03461744
- Where
- 3 sites in Finland
- Volunteers
- 482 people
- Sponsor
- Helsinki University Central Hospital