Clinical trials: Small Pulmonary Nodules
Pulmonary Nodule, Solitary, Pulmonary Cancer
Cios Mobile 3D Spin for Robotic Bronchoscopy
Evaluate the clinical utility and early performance of the Cios 3D Mobile Spin in conjunction with the Ion Endoluminal System, to visualize and facilitate the sampling of pulmonary nodules between 1-3 cm via the airway.
- Conditions
- Pulmonary Nodule, Solitary, Pulmonary Cancer, Lung Cancer, Lung Cancer, Nonsmall Cell
- Trial name
- NCT04740047
- Testing
- Ion Endoluminal System
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Mayo Clinic
Lung Cancer
Intra-op vs Pre-op Transbronchial Localization for Small Lung Nodule
Comparing pre-operative transbronchial localization under augmented fluoroscopy and intra-operative transbronchial localization using electromagnetic navigation bronchoscopy system for small lung nodules.
- Trial name
- NCT03793387
- Testing
- AF-guided endobronchial marking, ENB-guided endobronchial marking
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital Hsin-Chu Branch
Non-Small Cell Lung Cancer, Stage IA Non-Small Cell Lung Cancer
Segmentectomy Versus Lobectomy for Deep Solid-Dominant Early-Stage NSCLC
SOLID is a multicenter, open-label, randomized, controlled, phase III non-inferiority trial comparing anatomic segmentectomy with lobectomy in patients with deeply located, solid-dominant, clinical stage IA non-small cell lung…
- Trial name
- SOLID (NCT07698990)
- Testing
- Anatomic Segmentectomy, Anatomic Lobectomy
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Shanghai Chest Hospital
Non-Small Cell Lung Cancer
Station 4L Lymph Node Dissection Versus No Dissection in Clinical Stage I Solid Nodule-Type Invasive NSCLC
This multicenter, prospective, randomized clinical trial will enroll adults aged 18 to 75 years with resectable clinical stage I (T1-T2aN0M0) invasive non-small cell lung cancer presenting as a single solid nodule…
- Trial name
- NCT07801430
- Testing
- Station 4L Lymph Node Dissection
- Where
- China
- Volunteers
- 384 people
- Sponsor
- Fudan University
Lung Neoplasm, Thoracic Surgery, Video-Assisted
Application of 3D Printing Technique in Small Pulmonary Nodule Localization
The trial is to evaluate the efficacy and safety of three-dimensional printed navigational template in the clinical application of small peripheral lung nodule localization.
- Trial name
- NCT02952261
- Testing
- template-guided localization, CT-guided localization
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chang Chen
Lung Cancer, Lung Nodule
Intraoperative Imaging of Pulmonary Nodules by SGM-101
The primary objectives of this study are to assess the sensitivity and specificity of SGM-101 in detecting non-small cell lung carcinomas during surgery when excited by an near-infrared light source utilizing intraoperative…
- Conditions
- Lung Cancer, Lung Nodule, Non Small Cell Lung Cancer
- Trial name
- NCT04315467
- Testing
- SGM-101, Near infrared camera imaging system
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Sunil Singhal
Lung Cancer (Diagnosis)
Robotic Bronchoscopy for Small Lung Nodules Without a Bronchus Sign
The goal of this observational study is to learn about the diagnostic performance and safety of robotic-assisted bronchoscopy using the Ion Endoluminal System in adults with small lung nodules that do not show a bronchus sign on…
- Trial name
- NCT07862816
- Where
- 4 sites in South Korea
- Volunteers
- 151 people
- Sponsor
- Intuitive Surgical
Lung Cancer, Lung Non-Small Cell Carcinoma
From Benchmark to Surgical Activity: the Role of Endobronchial Fiducial Markers for Ground Glass Lung Nodules Resection.
With the risen popularity of low-dose computed tomography (LDCT) for lung cancer screening, many patients present with peripheral pulmonary ground-glass nodules (GGNs) with a suspicious solid part.
- Conditions
- Lung Cancer, Lung Non-Small Cell Carcinoma, Lung; Node
- Trial name
- Vortex_US (NCT05801406)
- Testing
- Tornado (Cook)
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Non Small Cell Lung Cancer, Lung Nodule
Evaluation of a Pneumotachograph (SPI) for the Production of PET and CT Acquisitions Synchronized With Breath for the Assessment of Extension of Lung Cancer
This is a pilot study, single-center, prospective, open-label, to assess the acceptability and performance of the experimental medical device (SPI) used during an imaging examination (PET / CT 4D imaging in synchronized mode…
- Trial name
- SPI COHERENCE (NCT01720186)
- Testing
- PET/CT 4D imaging in a synchronized mode centered on the thorax.
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Institut Claudius Regaud
Pulmonary Nodule, Solitary
Added Value of a Small Camera (Iriscope) in the Endoscopic Diagnosis of Peripheral Lung Nodules and Masses
Since the beginning of lung screening program in the different countries around the world by chest CT scan, numerous lung nodules and masses of unknown etiology are diagnosed.
- Trial name
- NCT05445635
- Testing
- Iriscope
- Where
- Belgium
- Volunteers
- 91 people
- Sponsor
- Erasme University Hospital
Lung Neoplasms
Safety and Feasibility of Pulmonary Surgery Marker System in the Intraoperative Localization of Small Pulmonary Nodules
As the detection of small pulmonary nodules continuously grows, the intraoperative localization of small pulmonary nodules is in great demand.
- Trial name
- NCT04211051
- Testing
- LungBrella marker implantation and VATS partial lobe resection
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Ruijin Hospital
Nodule Solitary Pulmonary, Non-small Cell Carcinoma
Nodify XL2 Classifier Clinical Utility Study in Low to Moderate Risk Lung Nodules
This study evaluates the how addition of the Nodify XL2 test result impacts the clinical management of newly identified solid lung nodules assessed as low to moderate risk of cancer.
- Trial name
- ALTITUDE (NCT04171492)
- Where
- 25 sites in United States, Canada
- Volunteers
- 2,000 people
- Sponsor
- Biodesix, Inc.
Lung Neoplasms, Lymph Node Excision
Mediastinal Lymph Node Dissection Versus Spared Mediastinal Lymph Node Dissection in Stage I GGN NSCLC
Lung cancer is the leading cause of cancer related death worldwide. Lobectomy or sub-lobectomy with mediastinal lymph node dissection is the standard surgery. About 50% lung nodules are pure ground-glass or part-solid nodules.
- Trial name
- NCT04631770
- Testing
- Systemic mediastinal lymph node dissection, Spared mediastinal lymph node dissection
- Where
- China
- Volunteers
- 1,362 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital