Clinical trials: Smoking, Tobacco
Tobacco Use Cessation, Second Hand Tobacco Smoke
Community-Partnered Dominican Republic Tobacco Control
Tobacco use and tobacco-caused illnesses and death are increasing in developing countries globally, so it is critical to study these countries in order to effectively address the tobacco epidemic.
- Trial name
- NCT01228916
- Testing
- Tobacco Cessation and Secondhand Smoke Reduction
- Where
- Dominican Republic
- Volunteers
- 3,273 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Additional, Effective Methods to Stop Smoking
Smoke-Free Living Study
The goal of this study is to provide you with an effective treatment for reducing the physical and emotional stress that can occur during the early phase of being without cigarettes.
- Trial name
- NCT00832806
- Testing
- Extended IVR (integrated voice response technology), Varenicline (Champix), IVR treatment
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Smoking Behaviors
Influence of Authorized Smokeless Tobacco Product Modified Risk Claims I: Consumer Product Demand
To explore consumer responses to the announcement and implementation of new modified risk claims for Copenhagen and General Snus (brands of smokeless tobacco (ST) products) using a series of complementary and innovative research…
- Trial name
- NCT07102082
- Testing
- Modified Risk - None, Modified Risk Claim
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Smoking Cessation
Facilitating Smoking Cessation With Reduced Nicotine Cigarettes
STUDY 1: INTERVENTION DEVELOPMENT The purpose of this study is to determine the best way to help people stop smoking by using very low nicotine content (VLNC) cigarettes.
- Trial name
- NCT02796391
- Testing
- Very Low Nicotine Content (VLNC) Cigarettes, One on One Counseling
- Where
- United States
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Tobacco Use Disorder
Computer-Based Stop Smoking Program in Assisting Doctors in Helping Adults Stop Smoking
RATIONALE: Computer-based stop smoking programs may assist doctors in helping patients stop smoking. PURPOSE: This randomized clinical trial is studying how well a computer-based stop smoking program works in assisting doctors in…
- Trial name
- NCT00383461
- Testing
- smoking cessation intervention, counseling intervention
- Where
- 2 sites in United States
- Volunteers
- 4,314 people
- Sponsor
- Brigham and Women's Hospital
Nicotine Addiction
Nicotinic Receptor Levels After Stopping Smoking
This positron emission tomography (PET) study examines the effects of 24 hours abstinence from smoking on return to availability of neuronal nicotinic receptors in slow and fast metabolizers of nicotine.
- Trial name
- NCT01704573
- Testing
- 2-[18F]-fluro-3-[2(S)-2-azethidinylmethoxy]-pyridine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania
Smoking Cessation
Adjustment of DOses of NIcotine in Smoking Cessation (ADONIS)
Nicotine replacement therapies (NRT) have proven efficacy to help smokers quit. However, their effectiveness is low. This study aims to answer the question: Does the dose adjustment of NRT according the saliva concentration of…
- Trial name
- ADONIS (NCT00235313)
- Testing
- Dose adjustment of nicotine replacement therapies, nicotine patch
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Environmental Tobacco Smoke Exposure, Depression
Healthy Outcomes of Pregnancy Education
The purpose of this study is to determine if an integrated intervention addressing active smoking, environmental tobacco smoke exposure, depression and intimate partner violence, would improve pregnancy outcome among African…
- Conditions
- Environmental Tobacco Smoke Exposure, Depression, Partner Abuse, Tobacco Smoking
- Trial name
- NCT00381823
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 1,750 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Smoking Cessation
Benefit of Systematic Proposition of Nicotine Substitution for Patients Undergoing Surgery
Smoking is associated with a higher rate of surgical complications. For example, in orthopedics, the risk of complications is 31% in smokers against 5% in non-smokers.
- Trial name
- PATCHIR (NCT04572646)
- Testing
- NRT proposition and exhaled CO measurement
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Groupe Hospitalier Mutualiste de Grenoble
Coronary Artery Disease, Smoking Cessation
PRISM-GENOMICS-Smoking Cessation for Patients With Coronary Artery Disease Undergoing Cardiac Catheterization or Having a Heart Attack at Barnes Hospital in St. Louis Mo
It has previously been shown that patients with coronary artery disease may have a harder time quitting smoking if they have a specific genetic profile and that these individuals have a better chance at quitting if they receive…
- Trial name
- NCT03383224
- Testing
- genotype-guided therapy, Nicotine patch, Smoking cessation counseling
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Washington University School of Medicine
Lung Cancer Screening, Smoking Cessation
Gain-framed Messages and NRT for Lung Cancer Screening Patients
This research is a randomized smoking cessation trial conducted within and specifically personalized for lung cancer screening patients presenting to a lung screening clinic.
- Trial name
- NCT03069924
- Testing
- Gain-framed messaging, Unframed messaging materials
- Where
- 2 sites in United States
- Volunteers
- 367 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Tabacco Use Disorder, rTMS
Personalized Brain Stimulation to Help Veterans Quit Smoking
Cigarette smoking is a significant public health concern for Veterans. Encouraging smoking cessation continues to be a top priority for the Veterans' Administration as Veterans who use tobacco experience negative health effects…
- Trial name
- VICTOR (NCT07050862)
- Testing
- Transcranial Magnetic Stimulation, Personalized-image-guided and E-field-modeling dose rTMS (precision TMS)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- VA Office of Research and Development
Tobacco Smoking
Smoking Prevalence at a University Hospital
Tobacco is the leading risk factor for avoidable mortality in France and around the world. It is also the second cause of life with disability in the world and the leading preventable risk factor for cancer in France and…
- Trial name
- TABAC-HCL (NCT03268980)
- Testing
- Questionnaire Hospital Staff group, Questionnaire students and patients group
- Where
- France
- Volunteers
- 11,276 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
E-cigarette Use, Tobacco Use Cessation
Attentional Bias Modification Training for E-cigarette Users
Aims are to (1) evaluate attentional bias to e-cigarette cues between the intervention and control groups at post-intervention as compared to the pre-intervention; and (2) test the feasibility and efficacy of the intervention at…
- Trial name
- NCT05112562
- Testing
- Computerized attentional bias modification training
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Milwaukee
Schizophrenia, Schizoaffective Disorder
Varenicline Treatment in Alcohol and Nicotine Dependent Patients With Schizophrenia
The aim of the proposed pilot study is to find out whether varenicline (ChantixTM) treatment decreases alcohol use and smoking in patients with schizophrenia or schizoaffective disorder.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Alcohol Dependence, Nicotine Dependence
- Trial name
- NCT00727103
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- State University of New York - Upstate Medical University
Smoking Cessation
The ESTxENDS Trial- Electronic Nicotine Delivery Systems (ENDS/Vaporizer/E-cigarette) as an Aid for Smoking Cessation.
Cigarette smoking is the leading cause of preventable death in Switzerland and still more than a quarter of the Swiss population smokes cigarettes.
- Trial name
- ESTxENDS (NCT03589989)
- Testing
- ENDS (vaporizer/e-cig) and smoking cessation counseling, Smoking cessation counseling
- Where
- 5 sites in Switzerland
- Volunteers
- 1,246 people, healthy volunteers welcome
- Sponsor
- University of Bern
Cigarette Smoking
Contingency Management and Pharmacotherapy for Smoking Cessation
In total, 70 smokers will be randomized to: standard of care smoking cessation medication varenicline alone (an FDA-approved smoking cessation medication) or varenicline plus contingency management (CM) (a behavioral procedure…
- Trial name
- Donaghue (NCT00683280)
- Testing
- contingency management, Standard of Care
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- UConn Health
Pregnancy
Prenatal Exposure Effects Psychophysiology Study
The purpose of the study is to understand the biology and behavior of early mother-infant attachment, and to investigate how it may be affected by prenatal substance exposures.
- Trial name
- PEEPS (NCT01134770)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Pregnancy, Smoking
A Mood Management Intervention for Pregnant Smokers
This proposal is aimed at testing the following hypotheses: 1. Cessation rates will be significantly greater for smokers in a mood management condition versus a health \& wellness condition during pregnancy and at 3 and 6 months…
- Trial name
- NCT00505869
- Testing
- Health & Wellness Intervention, Questionnaire, Mood Management Intervention
- Where
- United States
- Volunteers
- 338 people
- Sponsor
- M.D. Anderson Cancer Center
Smoking
Behavioral Activation Intervention, Reward Processing, and Youth Smoking Cessation
The primary purpose of this study is to develop a specialized behavioral activation treatment for smoking in youths ages 18-21 with elevated depressive symptoms.
- Trial name
- NCT01351766
- Testing
- Transdermal Nicotine Patch
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Maryland, College Park
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