Clinical trials: Smoking, Tobacco
Periodontitis, Periodontal Disease
Association of Periodontal Status and Smoking With Salivary Inflammasome Markers
The aim of this study is to evaluate the relationship between periodontal status and salivary levels of the inflammasomes NOD-like receptor family, pyrin domain containing 3 (NLRP-3), NOD-like receptor family, pyrin domain…
- Conditions
- Periodontitis, Periodontal Disease, Periodontal Health, Smoking
- Trial name
- NCT07312552
- Testing
- Periodontal examinations, Collection of saliva samples
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Smoking Cessation, Tobacco
Acceptability of Mobile Applications (Apps) to Enhance Smoking Cessation in a Clinical Tobacco Treatment Program - A Pilot Study
We will conduct a small-scale randomized controlled trial (RCT) with 24 adult smokers enrolled in the TTP. Participants will receive either the Free4Good mobile app for positive psychology skills training or a breathing…
- Trial name
- NCT05038852
- Testing
- smartphone applications
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- M.D. Anderson Cancer Center
Substance Use
Substance Use Screening Among Drug User
The purpose of this research is to improve the ability of primary medical staffs in screening and intervention for alcohol, benzodiazepines, and other illicit drug use.
- Trial name
- NCT02951858
- Testing
- Intervention Group, Control Group
- Volunteers
- 218 people
- Sponsor
- Shanghai Mental Health Center
Tobacco Use Disorder
Nicotine Regulation for Dual Users of E-cigarettes and Cigarettes
Cigarette smoking remains the leading cause of preventable morbidity and mortality in the US. Use of multiple tobacco products is becoming increasingly prevalent, with dual use of e-cigarettes and cigarettes representing the most…
- Trial name
- RDEC (NCT06614504)
- Testing
- Varying the nicotine content of cigarettes, Varying the nicotine content of e-cigarettes
- Where
- 2 sites in United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Smoking (Tobacco) Addiction
Impact of Exercise Associated With Cognitive-behavioral Therapy in Smokers
Smoking remains one of the leading causes of global morbidity and mortality, responsible for more than 8 million deaths annually, according to data from the World Health Organization.
- Trial name
- NCT07186049
- Testing
- Thesis Sessions, General Health Guidelines, Thesis and Exercises
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Agnaldo José Lopes
Smoking
Metabolism of NNK in Japanese Americans
The risk of lung cancer varies by individual and by ethnic/racial group. In this study the investigators will explore how individual differences in the metabolism of a tobacco-specific lung carcinogen may contribute to the…
- Trial name
- NCT04228952
- Testing
- Modified Natural American Spirit-Tan or Green cigarettes injected with labeled NNK
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Schizophrenia, Smoking Cessation
Varenicline and Smoking Cessation in Schizophrenia
There is a strong association between smoking and schizophrenia with prevalence rates ranging from 74% to 90%, versus a national average of 30% in nonschizophrenic individuals.
- Trial name
- VSCS (NCT01111149)
- Testing
- Sugar Pill, Varenicline, Bupropion HCl
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Minnesota
Smoking Cessation
The Impact of COVID-19 Pandemic on the Smoking Behaviour of Young Smokers and the Youth Quitline Service in Hong Kong
The aims of the present study are: 1. To explore the impact of COVID-19 pandemic on the smoking behavior of youth smokers 2. To explore the impact of COVID-19 pandemic on the Youth Quitline service in Hong Kong
- Trial name
- NCT04360863
- Testing
- Telephone survey
- Where
- Hong Kong
- Volunteers
- 150 people
- Sponsor
- The University of Hong Kong
Smoking Reduction, Smoking Behaviors
rTMS-concurrent Behavioral Priming for Reducing Smoking Cravings
The objective of this pilot clinical trial is to test the effects of different types of thinking strategies at the time of repetitive Transcranial Magnetic Stimulation (rTMS), applied to the left Dorsolateral Prefrontal Cortex…
- Trial name
- NCT06228235
- Testing
- Repetitive transcranial magnetic stimulation (rTMS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- West Virginia University
Smoking
Smoking Cessation in a Dentistry Setting
Aim: to assess relative effectiveness of a high and a low intensity intervention for smoking cessation support in a dental clinic setting.
- Trial name
- NCT00670514
- Testing
- Nix Individual, Fimpa dig fri
- Where
- Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Nicotine Dependence, Cigarette Smoking
Smoking Cessation for Smokers With Sleep Problems
This is a pilot research study examining two types of behavioral counseling along with the nicotine patch for smoking cessation.
- Conditions
- Nicotine Dependence, Cigarette Smoking, Insomnia
- Trial name
- NCT01277887
- Testing
- Cognitive-Behavioral Counseling, Smoking Cessation Counseling
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Yale University
Smoking Cessation, Asthma
Smoking Cessation Peds Asthma
The overall goal of this study is to adapt and preliminarily validate an intervention based on evidence based approaches to assist smoking parents and other family members of inner-city children ages 4 to 12 with asthma to stop…
- Trial name
- NCT02640521
- Testing
- Chart Reminders & New York State Quit line referral system
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- NYU Langone Health
Smoking Cessation, Nicotine Dependence
Comparing NicoBloc to Nicotine Lozenges
To examine the feasibility, acceptability, and preliminary impact of using NicoBloc compared to nicotine lozenges
- Trial name
- NCT03720899
- Testing
- NicoBloc, Nicotine Lozenge
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Alabama at Birmingham
Breast Cancer, Tobacco Dependence
Tobacco Dependence in Breast Cancer Patients Trial of Varenicline (Chantix)
Breast cancer patients who smoke, are at greater risk for treatment complications. The purpose of this study is to see if the researchers can find ways to help patients who have breast cancer quit smoking.
- Trial name
- NCT01532232
- Testing
- varenicline
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Nicotine Addiction, Cigarette Smoking
Abuse Liability of Reduced Nicotine Content Cigarettes in the Context of Concurrent E-Cigarette Use
Three hundred-twenty (320) adult smokers of menthol or non-menthol combustible cigarettes will be recruited and randomly assigned to one of five groups (n=64/group), who will be asked to switch for 12 weeks to ad libitum use of…
- Trial name
- DUAL (NCT02870218)
- Testing
- Smoking research cigarettes with e-cigarette, Nicotine discrimination thresholds
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Rose Research Center, LLC
Smoking Cessation
Varenicline for Treatment of E-cigarette Dependence
Varenicline is used to treat tobacco use dependence. It helps reduce cravings for tobacco use and decreases the pleasurable effects of cigarettes and other tobacco products.
- Trial name
- NCT05541497
- Testing
- Varenicline Tartrate
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Yale University
COPD
Electronic Cigarettes as a Harm Reduction Strategy Among Patients With COPD
The study team proposes a two-arm pilot study randomizing participants with COPD who smoke combustible cigarettes (CC) to counseling + NRT (standard of care) or counseling + e-cigarettes.
- Trial name
- NCT04465318
- Testing
- E-cigarette (EC), Nicotine Replacement Therapy (NRT), Smoking Harm Reduction Counseling Sessions
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- NYU Langone Health
Tobacco Use Cessation
Low-Cost Contingency Management for Smoking Cessation
An innovative low-cost form of contingency management has been developed in which participants receive the chance to draw vouchers from a fish bowl depending on whether or not their abstinence from tobacco is confirmed by…
- Trial name
- NCT01040260
- Testing
- Counseling, Contingency management, Nicotine patches
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Tobacco Use Disorder
Effect of Ramelteon on Smoking Abstinence
This is a randomized, double-blind, placebo-controlled crossover study to test whether a medication called ramelteon (Brand Name: Remeron) will help smokers quit and whether it reduces sleep problems that smokers experience…
- Trial name
- RAP (NCT02560324)
- Testing
- Ramelteon
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of Pennsylvania
Nicotine Dependence, Depression
Vigorous Exercise for Depressed Smokers
In this project the investigators will develop and pilot test a supervised, vigorous intensity exercise intervention for depressed female smokers.
- Trial name
- NCT01860924
- Testing
- exercise, health education
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
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