Clinical trials: Smoking, Tobacco
Nicotine Dependence
Human Laboratory Study Of Varenicline in Smokers
The purpose of this study is to test the ways that a drug called varenicline helps smokers to quit smoking. Varenicline is also called Chantix® and is approved by the United States Food and Drug Administration (FDA) to help…
- Trial name
- NCT00709696
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smoking Cessation
Comparison of Pharmacokinetic Profiles of 3 New Nicotine Gum Formulations With a Reference Gum
The purpose of the study is to compare the pharmacokinetic (PK) profiles and assess bioequivalence between three new nicotine gum formulations and a reference nicotine gum in healthy smokers.
- Trial name
- NCT02356913
- Testing
- Nicotine gum
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Fertin Pharma A/S
Smoking Cessation, Acceptability of Health Care
Re-Connect Application for Smoking Cessation
This series of studies will explore the acceptability, feasibility, and preliminary efficacy of making access to smartphone applications contingent on objective evidence of smoking abstinence.
- Conditions
- Smoking Cessation, Acceptability of Health Care, Nicotine Dependence, Cigarettes
- Trial name
- NCT05224154
- Testing
- Abstinent Contingent (AC) Re-Connect
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Rowan University
Cannabis Use, Tobacco
Lung Health and Breath Biomarkers: Acute Effects of Inhaled Cannabis
This outpatient study examines how inhaled cannabis, combustible or vaporized, alters lung health and breath biomarkers compared to a tobacco cigarette.
- Conditions
- Cannabis Use, Tobacco, Biomarkers
- Trial name
- NCT07694466
- Testing
- Cannabis (THC), Tobacco Cigarette
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hannah Harris
Lazertinib
A Randomized Phase II Study of LAZE rtiNib Alone Versus Lazertinib Plus bevaCizumab for NSCLC With EGFR + & Smoker
Using gefitinib or Osimertinib, an EGFR tyrosine kinase inhibitor (TKI), in patients with active mutations in epithelial cell growth factor receptors (EGFR), 70% response rate (CR+PR) and 90% disease control rate (CR+PR+SD)…
- Trial name
- NCT06156527
- Testing
- Lazertinib, Bevacizumab Injectable Product
- Where
- 5 sites in South Korea
- Volunteers
- 120 people
- Sponsor
- National Cancer Center, Korea
Smoking Cessation
Intervention for Support Persons to Help Smokers Quit
This study will examine the feasibility and potential effectiveness of an intervention for adults who want to help support a smoker to quit.
- Trial name
- NCT00379054
- Testing
- telephone based skills training intervention
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Tobacco Dependence
Testing the Effect of ENDS Flavors on Neurotransmission
The overarching goal of this translational proposal is to determine if neuroactive flavor chemicals can enhance the addiction potential of electronic nicotine delivery systems (ENDS) by altering brain function and behavior.
- Trial name
- TEN (NCT05836051)
- Testing
- Flavor
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Milton S. Hershey Medical Center
Risk Factor, Cardiovascular, Non-communicable Diseases
Epidemiology of Cardiovascular Diseases and Their Risk Factors in Regions of Russian Federation
The study carried out in 2012-2014 years. The aim was to evaluate the prevalence of CVD and their RF in different regions of the Russian Federation and to develop epidemiological models of the CVD risk profile for the population…
- Conditions
- Risk Factor, Cardiovascular, Non-communicable Diseases, Cardiovascular Diseases
- Trial name
- ECVD-RF (NCT04306822)
- Volunteers
- 22,906 people
- Sponsor
- National Research Center for Preventive Medicine
Smoking
Innovative Smartphone Application of a New Behavioral Method to Quit Smoking: Pilot Trial (Smart Quit)
This innovative study will compare a newly developed smartphone application for Acceptance and Commitment Therapy (ACT) to a smartphone application for traditional cognitive behavioral therapy (CBT).
- Trial name
- NCT01812070
- Testing
- ACT, CBT
- Where
- United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Tobacco Dependence
Healing and Empowering Alaskan Lives Towards Healthy-Hearts Study
This study aims to identify effective and cost-effective interventions for tobacco use and other risk behaviors for cardiovascular disease among Alaska Native people in rural villages.
- Trial name
- HEALTHH (NCT02137902)
- Testing
- Tobacco/Physical Activity Intervention, Diet plus BP/CHOL Intervention
- Where
- 2 sites in United States
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Stanford University
Physician's Role, Smoking Cessation
Personalized Tobacco Treatment in Primary Care (MOTIVATE)
This study examines the application of precision treatment intervention for smoking cessation from both the clinician perspective and patient perspective, and compares it to usual care on tobacco treatment in the primary care…
- Conditions
- Physician's Role, Smoking Cessation, Smoking
- Trial name
- NCT05846841
- Testing
- Precision Treatment, Usual Care
- Where
- United States
- Volunteers
- 850 people
- Sponsor
- Washington University School of Medicine
Substance-related Discorder
Effects of Smoking on Opioid Receptor Binding: A PET Study
Background: Tobacco smoking is one of the most preventable causes of morbidity and mortality in the world, but the addictive property of nicotine is such that fewer than 10 percent of people who attempt to quit smoking remain…
- Trial name
- NCT00618631
- Testing
- Nicotine, Carfentanil
- Where
- 2 sites in United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Smoking Cessation
Effect of Vernonia Cinerea Lozenges as a Smoking Cessation Aid in Patients With Non-communicable Diseases
Vernonia cinerea is an herbal which has been recorded in many Thai herbal formulation and Thai traditional medicine has used this herbal for treating various diseases included hypertension, asthma, fever, hepatitis, kidney stone…
- Trial name
- NCT06268002
- Testing
- Vernonia cinerea
- Where
- Thailand
- Volunteers
- 93 people
- Sponsor
- Chulalongkorn University
Smoking Cessation
Internet-Based Smoking Cessation for Operations Enduring Freedom and Iraqi Freedom (OEF/OIF) Veterans
The overarching aim of the study is to evaluate in a randomized trial the impact of an internet intervention compared to a standard clinic-based control group to promote smoking cessation among Operation Enduring Freedom and…
- Trial name
- NCT01001546
- Testing
- Internet-based, Standard Clinic-Based
- Where
- United States
- Volunteers
- 413 people
- Sponsor
- US Department of Veterans Affairs
Cigarette Smoking-Related Carcinoma
A Comprehensive Evaluation of Tobacco-Flavored vs. Non-Tobacco Flavored E-cigarettes on Smoking Behavior
This clinical trial compares the use of tobacco flavored electronic cigarettes (ECs) vs. non-tobacco flavored ECs vs. nicotine replacement therapy (patches and lozenges) on smoking behavior in current cigarette smokers.
- Trial name
- NCT06260683
- Testing
- Nicotine Replacement, Questionnaire Administration, Vaping
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Periodontal Diseases
Comparison of Salivary Biormarkers Levels With Periodontal Clinical Parameters in Smokers and Non-Smokers With Different Periodontal Diseases
To better understand the pathogenesis of chronic inflammatory diseases, the levels of various cytokines are commonly analyzed in tissues and biological fluids collected from the body.
- Trial name
- NCT06459037
- Testing
- Saliva obtaining
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Concentration of Exhaled Carbon Monoxide
Effect of Face Mask on Exhaled Carbon Monoxide of Smokers
Study of 120 healthy subjects without cardiovascular disease, 40 smokers of conventional cigarettes, 40 exclusive users of Heat-non-Burn Cigarettes and 40 nonsmokers.
- Trial name
- NCT04966845
- Testing
- measurement of concentration on exhaled Carbon Monoxide
- Where
- 2 sites in Greece
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Athens
Smoking, Endothelial Dysfunction
Hookah Smoking, Carbon Monoxide, and Coronary Endothelial Function
Hookah (water pipe) smoking is a new global epidemic. The World Health Organization wants to prohibit all claims that hookah is less harmful than cigarettes and wants hookah products to bear the same warning labels as cigarettes.
- Trial name
- NCT03166787
- Testing
- Charcoal hookah, E-coal hookah, Cigarette
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Smoking, HIV Infections
Smoking Cessation Using Motivational Therapy and Varenicline
People that are infected with HIV appear to be especially susceptible to the adverse effects of cigarette smoking. The purpose of this study is to determine if quitting smoking by using a specialized smoking cessation treatment…
- Trial name
- NCT00701896
- Testing
- Varenicline tartrate, Nicotine Replacement Therapy, Biological Control
- Where
- United States
- Volunteers
- 294 people
- Sponsor
- Philip Diaz
Cigarette Smoking-Related Carcinoma
A Smartphone Application (QuitBot) for the Improvement of Smoking Cessation Among American Indians and Alaska Natives, NAITIVE Trial
This clinical trial develops a chatbot smartphone application (app), QuitBot, and text messaging to help American Indians (AI) and Alaska Natives (AN) to quit smoking commercial tobacco (smoking cessation), and evaluates two…
- Trial name
- NCT06697496
- Testing
- QuitBot Smoking Cessation Chatbot Program, QuitBot Smoking Cessation Text Messaging Program, Survey Administration
- Where
- United States
- Volunteers
- 772 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.