Clinical trials: Smoking, Tobacco
Smoking Cessation
Efficacy of 2 Probiotics During Nicotine Replacement Therapy on Withdrawal Symptoms Associated With Smoking Cessation
Quitting smoking is a big decision, a decision to achieve better health. Trying to quit smoking can be stressful. The prospect of dealing with withdrawal symptoms, fear or failure to change the routine, can also be sources of…
- Trial name
- NCT02492022
- Testing
- Probiotic L008-1, Probiotic L008-2
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- Lallemand Health Solutions
Smoking, Tobacco
Proactive Population Health Strategy to Offer Tobacco Dependence Treatment to Smokers
Health care systems are key channels for delivering tobacco cessation treatment to the smokers in a population. A population-based approach could complement office-based care and offload busy clinicians.
- Trial name
- NCT03612895
- Testing
- Internal Care Coordination, External Community Referral, Usual Care
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- Massachusetts General Hospital
Cigarette Smoking, Smoking Cessation
Impacto 2.0: Mobile Smoking Cessation Across Texas
This is a preliminary efficacy trial that will examine whether Impacto 2.0 produces higher rates of biochemically verified smoking abstinence among Hispanic adults across Texas compared to the NCI quitSTART app.
- Trial name
- NCT07915973
- Testing
- Impacto 2.0, quitSTART
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Michael J. Zvolensky, Ph.D.
Smoking
CSD170304: Study to Assess Nicotine Uptake in Smokers From Electronic and Combustible Cigarettes
To determine the rate and amount of nicotine uptake with 10-minute ad libitum use of five different marketed electronic cigarettes, or one combustible cigarette (CC).
- Trial name
- NCT03294356
- Testing
- FT210771, FT210751, 6T30134157764
- Where
- 5 sites in United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Periodontal Diseases, Smoking
Effect of Smoking on Periodontal Therapy in Periodontitis
The present study aimed to assess the effect of smoking on non-surgical periodontal treatment on serum and salivary RANKL, OPG and IL34 levels in periodontitis stage III grade C (P-III-C) patients.
- Trial name
- NCT05262153
- Testing
- Non-surgically performed scaling and root planing
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Smoking
European Exposure Study
The current study was designed to determine the exposure of adult smokers and non-smokers to cigarette smoke constituents through evaluation of selected biomarkers of exposure.
- Trial name
- NCT01237912
- Where
- United Kingdom
- Volunteers
- 1,667 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Smoking
Study of Nicotine Patch in Pregnancy (SNIPP)
There are no established evidences as to the effectiveness in smoking pregnant women of nicotine patches in increasing birth weight, smoking abstinence during pregnancy and concerning the safety their for the fetus/newborn.
- Trial name
- SNIPP (NCT00507975)
- Where
- 2 sites in France
- Volunteers
- 404 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Smoking, Schizophrenia
Acetylcholine, Tobacco Smoking, Genes and Nicotinic Receptors
The purpose of the study is to measure the sensitivity of NCFHEB binding to changes in endogenous acetylcholine levels in healthy smoking and nonsmoking subjects, and in schizophrenic smoking and nonsmoking subjects.
- Trial name
- nic_physo (NCT02008292)
- Testing
- Physostigmine
- Where
- 3 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yale University
PASSIVE SMOKING ,, RESPIRATORY SYSTEM MECHANICS,
Effects Of Passive Smoking On The Respiratory System Mechanics Of Healthy Non-Smokers In Different Body Positions
The study will examine changes in the respiratory system mechanics and in respiratory physiology after exposure of subjects to passive smoking.
- Trial name
- NCT02171871
- Testing
- exposed to a smoking environment
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hellenic Anticancer Society
Nicotine Dependence, Electronic Cigarette Use
E-cigarette Nicotine Study
This is a pilot randomized controlled trial (RCT) with the overarching aim of testing the influence of reducing electronic nicotine delivery system (ENDS) use or nicotine on addiction and combustible cigarette (CC) smoking among…
- Conditions
- Nicotine Dependence, Electronic Cigarette Use, Cigarette Smoking
- Trial name
- NCT04709471
- Testing
- Nicotine, Juul e-cigarette, Reduction
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Smoking Cessation
Safety and Efficacy Study of Topiramate to Aid in Smoking Cessation
The purpose of this research study is to determine if topiramate is safe and effective in the treatment of smoking cessation
- Trial name
- NCT00280839
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Lindner Center of HOPE
Tobacco Use Disorder
Evaluation of Oral Tobacco as a Harm Reduction Method for Smokers
Recently, tobacco companies have developed new oral tobacco products that are purportedly less harmful than conventional tobacco products.
- Trial name
- NCT00711100
- Testing
- Camel Snus, Marlboro Snus, Stonewall
- Where
- 2 sites in United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smoking Cessation, Biofeedback
Personalized Intervention Program: Tobacco Treatment for Patients at Risk for Lung Cancer (PIP)
The purpose of this study is to test the efficacy of two separate, sequential interventions to promote tobacco cessation/reduction in patients who are screened for lung cancer or are eligible for lung cancer screening.
- Trial name
- NCT02658032
- Testing
- personalized cessation care, bio feedback, standard care
- Where
- 2 sites in United States
- Volunteers
- 276 people
- Sponsor
- Yale University
Tobacco Use Cessation, Smoking Cessation
Evaluating the Impact of a Photoaging App Versus School-Based Educational Intervention on Adolescents' Knowledge, and Attitudes Towards Tobacco Use
Tobacco use is a leading cause of preventable morbidity and mortality worldwide. It has been estimated that by 2030, tobacco use will cause approximately 10 million deaths per year worldwide, with 70% of those occurring in low…
- Conditions
- Tobacco Use Cessation, Smoking Cessation, Smoking Prevention
- Trial name
- NCT06483763
- Testing
- SmokerFace App from the Education Against Tobacco (EAT) program, The use of standardized school-based educational module
- Where
- Oman
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Sultan Qaboos University
Cardiovascular Diseases, Heart Diseases
Promoting Smoking Cessation and Reducing Weight Gain
To test whether a behavioral intervention could indeed achieve the dual goals of promoting smoking cessation and minimizing weight gain.
- Trial name
- NCT00113711
- Testing
- smoking cessation, reducing diet
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Smoking Cessation
Latinos Kick Buts: Mobile Engagement and Cessation Support for Latino Smokers
Latino Kick Buts (LKB) is a smoking cessation treatment program available to patients identified as smokers at the University of Rochester Medical Center.
- Trial name
- NCT05278481
- Testing
- Reward Message with standard introduction, Reward Message with culturally tailored introduction, Threat/Self-efficacy with standard introduction
- Where
- United States
- Volunteers
- 408 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Smoking, COPD
Nurse Smoking Cessation of Patients With Chronic Obstructive Pulmonary Disease (COPD) With Nicotine Replacement Therapy (NRT) and Behavioral Support
This is a smoking cessation study with COPD patients where the researchers wanted to evaluate if nicotine sublingual tablets or placebo combined with low or high individual support could increase ½ and 1 year quit rates.
- Trial name
- NCT00132236
- Testing
- nicotine sublingual tablets, low and high behavior support
- Where
- 7 sites in Denmark
- Volunteers
- 300 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Therapeutic Equivalency
Fed, Bioequivalence Study of Pravastatin Sodium 80 mg Tablets Versus Pravachol® 80 mg Tablets In Subjects
This study was designed to compare the rate and extent of absorption of pravastatin sodium from the following formulations under fed conditions: 1. Pravastatin Sodium 80 mg Tablets (Genpharm Inc. Canada) 2.
- Trial name
- NCT00648544
- Testing
- Pravastatin
- Where
- Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Mylan Pharmaceuticals Inc
Tobacco Use Disorder, Smoking Cessation
p16 Methylation for Smoking Cessation
Smoking cessation is often difficult for smokers to achieve for a variety of reasons including: difficulty with nicotine withdrawal, failure to perceive the benefits of smoking cessation, and failure to perceive the risks…
- Conditions
- Tobacco Use Disorder, Smoking Cessation, Lung Cancer
- Trial name
- NCT01038492
- Testing
- p16 Methylation and Lung Cancer Education
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Duke University
Tobacco Use
Expanding the Click City Tobacco Prevention Program to Include E-cigarettes and Other Novel Tobacco Products
The goal of this study is to modify a smoking prevention program for 5th and 6th grade students to also target vaping e-cigarettes.
- Trial name
- NCT03682900
- Testing
- Click City®: Tobacco, Usual Tobacco Curriculum
- Where
- United States
- Volunteers
- 2,673 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
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