Clinical trials: Smoking
Smoking
Reduced Exposure Study in Smokers Using THS 2.2 With 5 Days in a Confinement Setting.
The overall goal of the study is to evaluate if the ad libitum use of the Tobacco Heating System 2.2 (THS 2.2) for 5 days by adult healthy smokers results in a reduction in the levels of biomarkers of exposure (BoExp) for…
- Trial name
- NCT01959932
- Testing
- Tobacco Heating System (THS 2.2), Smoking abstinence (SA), Conventional cigarette (CC)
- Where
- Poland
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Smoking, Tobacco Dependence
Using a Teachable Moment Communication Process to Improve Outcomes of Quitline Referrals
This study will compare the effectiveness of two approaches for delivering smoking cessation advice in the primary care setting.
- Trial name
- NCT02764385
- Testing
- Teachable Moment Communication Process, AAC
- Volunteers
- 15,786 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Hypertension, Hyperlipidemia
Prioritized Clinical Decision Support (CDS) to Reduce Cardiovascular Risk
The objective of this project is to develop and implement sophisticated point-of-care Electronic Health Record (EHR)-based clinical decision support that (a) identifies and (b) prioritizes all available evidence-based treatment…
- Conditions
- Hypertension, Hyperlipidemia, Diabetes, Smoking
- Trial name
- NCT01420016
- Testing
- Prioritized Clinical Decision Support
- Volunteers
- 7,914 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Smoking Cessation
Enhanced E-cigarette Coaching Intervention for Dual Users of Cigarettes and E-cigarettes
The purpose of this study is to develop and pilot test an enhanced behavioral coaching intervention for dual users of cigarettes and electronic nicotine delivery systems (ENDS) who call tobacco quitlines for help quitting smoking.
- Trial name
- NCT03575468
- Testing
- Enhanced E-cigarette Coaching, Quitline treatment as usual
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Consumer Wellness Solutions
Smoking, Smoking Cessation
Treating Caregivers Who Smoke at AFCH
The purpose of this research study is to 1) see if a smoking cessation program is something that caregivers will use while their child is hospitalized, 2) see if caregivers think this program is something we should institute…
- Trial name
- NCT06051474
- Testing
- Nicotine Replacement Product
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Smoking Cessation
BE Smokefree: Behavioral Economics Incentives to Engage Adolescents in Smoking Cessation
More than 90% of adult smokers initiate tobacco use before age 18, making prevention and treatment of adolescent smoking a critical health priority.
- Trial name
- NCT03670264
- Testing
- Quitline Incentive, Tobacco Cessation Incentive, Way to Health (WTH) Platform
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Smoking Cessation, Harm Reduction
Assisting Smokers to Switch to a JUUL E-Cigarette by Devaluing Combustible Cigarettes
This study will evaluate a reward devaluation strategy in which smokers use the JUUL e-cigarette immediately before any combustible cigarettes (CCs) are smoked.
- Conditions
- Smoking Cessation, Harm Reduction, E-Cig Use, Cigarette Smoking
- Trial name
- RECON (NCT04188197)
- Testing
- JUUL
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rose Research Center, LLC
Smoking Cessation
Nicotine Lozenge Bioequivalence Study
To compare the bio equivalence of new nicotine lozenge formulation with the reference nicotine lozenge so as to deliver the same nicotine blood profile.
- Trial name
- NCT01536704
- Testing
- Nicotine (2 mg), Nicotine (4 mg)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Smoking Cessation
Comparison of Conservative and Aggressive Smoking Cessation Treatment Strategies in a Vascular Surgery Office Practice
The aim of this study is to prove that the use of Bupropion with counseling works better than counseling alone for patients to quit smoking.
- Trial name
- NCT01850589
- Testing
- Aggressive Therapy
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Nicotine Dependence
Effects of Varenicline on Brain Activity During Nicotine Abstinence
This project aims to define mechanisms through which varenicline might be an effective smoking cessation medication.
- Trial name
- NCT00602927
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Smoking, Cigarette
The Impact of Standardized Tobacco Product Packaging on Young Adults in the Retail Environment
The overall aim of this research is to experimentally evaluate the extent to which partially standardizing the color of tobacco packaging influences tobacco use intentions among young adults who have varying levels of tobacco use…
- Trial name
- NCT05973981
- Testing
- Package standardization
- Where
- United States
- Volunteers
- 433 people, healthy volunteers welcome
- Sponsor
- RAND
Smoking, Cigarette, Breastfeeding
Lung and Breast Cancer Prevention by an Integrated Intervention of Maternal Smoking Cessation and Breastfeeding
This pilot clinical trial aims to integrate maternal smoking cessation and breastfeeding interventions to enhance both cancer prevention behaviors.
- Trial name
- NCT05123118
- Testing
- Integrated intervention of smoking cessation and breastfeeding
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Xiaozhong Wen
Tobacco Use Disorder
Low Nicotine Content Cigarettes in Vulnerable Populations: Affective Disorders
While the prevalence of smoking in the United States general population has declined over the past 50 years, there has been little to no decline among people with mental health conditions.
- Trial name
- NCT04090879
- Testing
- Either normal nicotine content cigarettes (15.8mg/g) or reduced nicotine content cigarettes (0.4mg/g), E-Cigarettes
- Where
- 2 sites in United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Brown University
Nicotine Dependence
An Effectiveness Trial of Maintenance Therapy for Nicotine Dependence
The transdermal nicotine patch is the most widely used form of tobacco dependence treatment in the US and Europe, but most smokers are unable to successfully quit with this form of treatment.
- Trial name
- NCT01047527
- Testing
- Transdermal nicotine patch
- Where
- 2 sites in United States
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Tobacco Use Disorder
Pilot Study of Nicotine Replacement for Smoking Cessation During Pregnancy
We plan to examine the feasibility, acceptability, preliminary quit rates, overall nicotine exposure and adverse effects of the nicotine inhaler for smoking cessation in pregnancy.
- Trial name
- NCT00888979
- Testing
- Nicotrol Inhaler
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Nicotine Dependence
Health Effects of SLT, Cigarette Smoking, and New Tobacco Products
The use of smokeless tobacco (ST) as a substitute for cigarette smoking has been suggested since it is considered by some to be a less harmful tobacco product (Russell, Jarvis and Feyerabend, 1980; Russell et al, 1981; Rodu…
- Trial name
- ANTS3 (NCT00469079)
- Testing
- Nicotine gum and lozenge, Taboka, Camel Snus
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smoking, Tobacco Use Cessation
Group Therapy for Nicotine Dependence: Mindfulness and Smoking
The goal of this behavioral research study is to create and study a Mindfulness-Based Addiction Treatment (MBAT) for nicotine dependence.
- Trial name
- NCT00297479
- Testing
- MBAT Group Therapy, Nicotine, Group Therapy
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Obesity, Smoking Cessation
Addressing Post Cessation Weight Gain
Some individuals smoke with the perception that smoking helps control body weight. Smokers gain an average of as much as 10 pounds in the months following smoking abstinence, with heavier and more-dependent smokers gaining more…
- Trial name
- NCT02412631
- Testing
- lorcaserin, Varenicline
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Tobacco Use Disorder
Innovative Interventions for Smoking Cessation
The purpose of this study is to evaluate the effect of a combination of the 21 mg nicotine patch and very low nicotine content (VLNC) cigarettes compared to 21 mg nicotine patch only and very low nicotine content cigarette only…
- Trial name
- NCT01050569
- Testing
- Nicotine Patch, VLNC Cigarette, VLNC Cigarette Plus Nicotine Patch
- Where
- 2 sites in United States
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smoking Cessation
Neuro Biomarkers of Smoking Behavior
The purpose of this study is to evaluate cognition in smokers and nonsmokers. It involves administration of intranasal insulin (Novolin R), an investigational medication followed by a brief non-invasive cognitive test.
- Trial name
- NCT03811951
- Testing
- Novolin R
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago