Clinical trials: Smoking, open to volunteers
Smoking
Using Smartwatches to Monitor Smoking in Real-life Situations
Background: It is important to quickly identify when people are at risk of smoking. Most current methods rely on people reporting when they smoke or what makes them want to smoke.
- Trial name
- NCT07067151
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute on Minority Health and Health Disparities (NIMHD)
Tobacco Dependence
Effectiveness of Volitional Help Sheets as an Adjunct to Treatment to Promote Behavior Change: A Pilot Study on Smoking
Smoking is a major public health concern associated with substantial morbidity and premature mortality. Planning may help people who wish to change their smoking behavior by translating their intentions into action.
- Trial name
- VHS_T (NCT07910214)
- Testing
- Smoking-Specific Volitional Help Sheet
- Where
- France
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- Clinique de la Mitterie
Alcohol Drinking
Nicotinic Receptor Genetic Variation and Alcohol Reward
Background: People with the brain disease AUD (alcohol use disorder) have a serious problem with drinking. Researchers want to study how different people react to alcohol, and how genes affect this.
- Trial name
- NCT03294460
- Testing
- Alcohol (Oral), Alcohol (IV), Alcohol (Ethanol)
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Cigarette Smoking-Related Carcinoma
PK/PD of Vaping THC-containing Liquids vs. Smoked Cannabis
We will conduct a randomized, within-subjects clinical study to compare short-term pharmacokinetic (PK) and pharmacodynamic (PD) effects of Δ9-tetrahydrocannabinol (THC) vaping liquids vs.
- Trial name
- NCT06055231
- Testing
- Vape device, Joint, Marijuana via vape device
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Tobacco Products, Smoking Behavior
Communicating About Nicotine Reduction in Cigarettes
The goal of this clinical trial is to learn how a messaging campaign about reduced nicotine cigarettes and policy, combined with the use of very low nicotine cigarettes (VLNCs), affects smoking behavior and attitudes among adult…
- Conditions
- Tobacco Products, Smoking Behavior, Cigarette Use
- Trial name
- NCT06787937
- Testing
- VLNC messages, Control message
- Where
- 2 sites in United States
- Volunteers
- 1,230 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Wound Surgical, Diabetes
Negative Pressure Wound Therapy Devices in Total Knee Arthroplasty
This study is a single-center, prospective, randomized, open-label clinical trial evaluating three commercially available closed-incision negative pressure wound therapy (ciNPWT) devices: NPseal, PICO, and Prevena, in adult…
- Conditions
- Wound Surgical, Diabetes, Obesity, Chronic Kidney Diseases
- Trial name
- NCT07770633
- Testing
- NP Seal, PICO, Prevena
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Oral Potentially Malignant Disorders, Oral Lichen Planus
Salivary IL-8 and Serum IL-6 as Biomarkers for Oral Potentially Malignant Disorders in Smokers and Never-Smokers
The goal of this observational study is to learn whether two inflammatory proteins, interleukin-8 (IL-8) measured in saliva and interleukin-6 (IL-6) measured in blood serum, can help distinguish adults with oral potentially…
- Conditions
- Oral Potentially Malignant Disorders, Oral Lichen Planus, Oral Leukoplakia, Oral Squamous Cell Carcinoma
- Trial name
- NCT07915570
- Testing
- Salivary IL-8 and Serum IL-6 Measurement
- Where
- Egypt
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Smoking (Tobacco) Addiction
Addiction Potential of Very Low Nicotine Filtered Little Cigars
The goal of this clinical trial is to learn how reducing the nicotine content in filtered little cigars can affect the the use of these cigars and lung health in current adult filtered little cigar users.
- Trial name
- LOWFLC (NCT06630728)
- Testing
- Reduced Nicotine Content Cigars, Normal nicotine content cigar, Usual brand cigar
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Cigarette Smoking-Related Carcinoma
iCanQuit Smoking Cessation Among Hispanic Adults
This phase III trial compares a smartphone application with or without nicotine replacement therapy in improving smoking cessation among Hispanic adults who would like to quit smoking.
- Trial name
- NCT06811038
- Testing
- iCanQuit Smartphone App Smoking Cessation Program, Nicotine Gum, Nicotine Patch
- Where
- United States
- Volunteers
- 854 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Asperger's Disorder, Asperger Disorder
QAIAx - SGI/SI Smart Health Cities: Microcity Enclave Program (Quantum SI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360; USPTO EO 9424 Assignment ID: 2101042 / ARN: REEL/FRAME: 76481/0026 - OUSD-R&E, Department of War)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum SI/SGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.
Cigarette Smoking-Related Carcinoma
Studying Different Ways of Using Oral Nicotine Pouches to Understand the Effect on Nicotine Delivery, Appeal, and Side Effects Among Adult Cigarette Smokers
This clinical trial studies how different ways of using oral nicotine pouches (ONPs) affect nicotine delivery, appeal, and side effects among adult cigarette smokers.
- Trial name
- NCT07899827
- Testing
- Biospecimen Collection, Oral nicotine pouches, Survey Administration
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Focus of the Study is Smoking Cessation and Prevention, Smoking Prevention
Effectiveness Of Project EX: A Classroom-Based Smoking Prevention And Cessation Intervention Program
The goal of this intervention is to learn if Project EX helps in prevention and cessation of smoking in adolescents. The main question it aims to answer is: 1.
- Trial name
- NCT07895784
- Testing
- Project EX
- Where
- Pakistan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Karachi
Chronic Obstructive Pulmonary Disease (COPD), Smoking
Collection of Airway, Blood and/or Urine Specimens From Subjects for Research Studies
The purpose of this study is to obtain biologic materials from the blood, airways and/or urine of normal individuals and individuals with lung disease.
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Smoking, Smoking Cessation, Idiopathic Pulmonary Fibrosis (IPF)
- Trial name
- NCT01776398
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Cigarette Smoking-Related Carcinoma
Sensory Tests of Cigarettes for Identification of Flavors in Current Daily Smoking Adults
This clinical trial tests how well current daily smoking adults can identify flavors of cigarettes. Menthol cigarettes account for 31 percent of cigarettes sold in the United States.
- Trial name
- NCT06816459
- Testing
- Cigarette smell test, Cigarette Taste Test, Study questionnaires
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Smoking Behaviors
Therapeutic Contact Intensity in a Psychological Smoking Cessation Intervention With an App
This randomized controlled trial intends to examine the efficacy of a smoking cessation intervention with an App according to the intensity of therapeutic contact. Participants will be assigned to one of three groups.
- Trial name
- TREATINTSMOKE (NCT06900985)
- Testing
- 8-sessions CBT + App, 4-sessions CBT+App, Smoking cessation App
- Where
- Spain
- Volunteers
- 429 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Smoking Cessation, Nicotine Replacements Therapy
A Study of Nicotine Orodispersible Tablet on Craving Relief of Male and Female Smoker Volunteers
The objective of the study is to evaluate the relief of momentary urge to smoke at pre-specified early post-dose time points after administration of Nic ODT compared to Placebo ODT.
- Trial name
- Zippy PD (NCT07893158)
- Testing
- Nicotine Mint Oro Dispersible Tablet (Nic ODT)
- Where
- Canada
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- McNeil AB
Smoking, Tobacco
A Study to Determine the Effect of Access to Multiple Tobacco Flavor Options on Smoking Abstinence Among Primary Cigarette Smokers Using an Electronic Nicotine Delivery System
This is a multi-site, open-label, single arm study to evaluate the rate of smoking abstinence by the end of the study with healthy adult consumers of cigarettes when provided with an e-cigarette over a 13 week study period.
- Trial name
- NCT07879638
- Testing
- FT25614, FT25615, FT25616
- Where
- 5 sites in United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Lung Cancer (Diagnosis), Smoking Cessation
Impact of Lung Cancer Screening With Chest Scans Combined With Coaching on Smoking Cessation in Heavy Smokers
Lung cancer is common and serious, but when detected early, the chances of recovery are significantly better. Tobacco use is the leading cause.
- Conditions
- Lung Cancer (Diagnosis), Smoking Cessation, Lung Neoplasm
- Trial name
- NCT07860359
- Testing
- Image-Based Counseling, Smoking Cessation Coaching, Low-Dose Chest Computed Tomography (LDCT)
- Where
- Switzerland
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Hôpital Fribourgeois
Cigarette Smoking-Related Carcinoma
A Smartphone Application (QuitBot) for the Improvement of Smoking Cessation Among American Indians and Alaska Natives, NAITIVE Trial
This clinical trial develops a chatbot smartphone application (app), QuitBot, and text messaging to help American Indians (AI) and Alaska Natives (AN) to quit smoking commercial tobacco (smoking cessation), and evaluates two…
- Trial name
- NCT06697496
- Testing
- QuitBot Smoking Cessation Chatbot Program, QuitBot Smoking Cessation Text Messaging Program, Survey Administration
- Where
- United States
- Volunteers
- 772 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Smoking Behaviors, Smoking ( Cigarette)
A Study to Assess Nicotine Uptake From a Menthol Electronic Nicotine Delivery System Product
This will be a randomized, open-label, 2-way crossover, single-site study designed to evaluate elements of abuse liability (AL), including subjective effects and physiological measures (pharmacodynamics [PD]), and plasma nicotine…
- Conditions
- Smoking Behaviors, Smoking ( Cigarette), Tobacco Use, Abuse Liability
- Trial name
- NCT07881848
- Testing
- Menthol 5%, Combustible cigarette
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- RAI Services Company