Clinical trials: Smoking ( Cigarette)
Smoking, Smoking, Tobacco
Bupropion and Cigarette-Related Cues in Smokers
Randomized, double-blind, before-after controlled trial to assess changes in regional brain activation in response to cigarette-related cues from before to after treatment with bupropion (vs placebo).
- Trial name
- NCT03920319
- Testing
- Bupropion
- Volunteers
- 34 people
- Sponsor
- University of California, Los Angeles
Smoking
Evaluation of Environmental Emissions From Electronic Cigarettes and Tobacco-Burning Cigarettes
This study will assess environmental emissions of selected compounds in a test chamber after cigarette smoking or e-cigarette vaping.
- Trial name
- NCT02185898
- Testing
- Leading U.S. non-menthol cigarette, Leading U.S. menthol cigarette, Electronic cigarette #1
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- R.J. Reynolds Vapor Company
Tobacco Use Disorder/Cigarette Smoking
Smoking Cessation Intervention for Young Adults Using MTM: A Randomized Controlled Trial
The goal of this clinical trial is to evaluate whether a Multi-Theory Model (MTM)-based behavioral intervention can effectively promote smoking cessation and support behavior change in young adult cigarette smokers aged 18 to 29…
- Trial name
- NCT07104006
- Testing
- Multi-Theory Model (MTM)-Based Smoking Cessation Program
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- University of Nevada, Las Vegas
Smoking, Smoking Cessation
Connect to Quit for Smoking
The purpose of this research study is to examine the effectiveness of an intervention designed to reduce smoking in low income veterans within a regional United States Veterans Administration(VA) health care system.
- Trial name
- CTQ (NCT01299896)
- Testing
- Coordinated Care, Usual Care
- Where
- United States
- Volunteers
- 633 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Electronic Cigarette Use
Nicotine Uptake, Measures of Abuse Liability, and Puffing Topography With Use of RELX ENDS Products by ENDS Consumers
This study is being conducted to evaluate nicotine uptake, the potential abuse liability, and puffing topography associated with the use of an electronic nicotine delivery system (ENDS) with tobacco- and menthol-flavored…
- Trial name
- NCT04620616
- Testing
- RELX ENDS Tobacco Flavor, RELX ENDS Menthol Flavor, Subject Usual Brand ENDS
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Cheerain HK Limited
Smoking, Tobacco
A RCT to Determine the Effect of ENDS Flavor Availability on Abstinence Within Smokers
The overall purpose of this study will be to assess primary combustible cigarette users' abstinence from smoking their usual brand of combustible cigarettes at the end of the study, when provided with an electronic nicotine…
- Trial name
- NCT07172438
- Testing
- P2611222, P2615022, P2615122
- Where
- 27 sites in United States
- Volunteers
- 668 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Nicotine Dependence
Combination Nicotine Patch / Lorcaserin for Smoking Cessation
This study plans to compare the efficacy of the nicotine patch / lorcaserin combination treatment vs. the nicotine patch alone in terms of leading to a reduction in smoking behavior and withdrawal symptoms.
- Trial name
- LorNic (NCT02906644)
- Testing
- lorcaserin, nicotine patch
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Duke University
Cigarette Smoking
Effects of Choice Bundling on Valuation of Delayed Gains and Losses in Cigarette Smokers
The present study will investigate the effects of choice bundling, in which a single choice produces a series of repeating consequences, on valuation of delayed monetary gains and losses in an online panel of cigarette smokers.
- Trial name
- NCT05110716
- Testing
- Bundle-size 1, Bundle-size 3, Bundle-size 9
- Where
- United States
- Volunteers
- 308 people
- Sponsor
- Virginia Polytechnic Institute and State University
Cigarette Smoking, Nicotine Dependence
Smokers' Response to Nicotine Dependence Genotyping
Innovative strategies to reduce adult smoking prevalence include using genetic information to motivate cessation and, ultimately, to tailor cessation pharmacotherapy.
- Trial name
- NCT01780038
- Testing
- Receipt of Genetic Results, No results given
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Electronic Cigarette Use
Effects of E-cigarette Use on Health
Electronic nicotine delivery systems (ENDS) are used by millions of Americans, however their long-term health effects are unknown.
- Trial name
- VAPECHECK (NCT06610838)
- Testing
- Health Assessments
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Acute Lung Injury
The Study of ELEctronic Cigarette Toxicity in a Human Model in Vivo Model of Inflammation and Vascular Dysfunction
To carry out a prospective cohort study of healthy volunteers, assessing differences between baseline pulmonary inflammation, response to LPS inhalation and endothelial function, as measured by flow mediated dilation between…
- Trial name
- SELECT (NCT02739438)
- Testing
- Electronic cigarette use, Cigarette use, Control group
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Cigarette Smoking
Nicotine Pharmacokinetics From Research Electronic Nicotine Delivery System S-TA-U001 in Smokers and E-Cigarette Users
To better understand the PK and associated pharmacodynamic (PD) responses produced by the Research ENDS S-TA-U001 product, this study will compare the Research ENDS S-TA-U001 to The subject's own brand combustion (non-menthol)…
- Trial name
- NCT02792426
- Testing
- Research ENDS S-TA-U001, Nicorette Inhalator
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- NJOY, Inc.
Nicotine Dependence
Mechanistic Evaluations of Pre-Cessation Therapies for Smoking Cessation
The purpose of this study is to look at brain function in order to understand how different treatments work to help people quit smoking.
- Trial name
- ConNicBrain (NCT01406223)
- Testing
- Varenicline, Bupropion, Nicotine patches
- Where
- 2 sites in United States
- Volunteers
- 282 people
- Sponsor
- Duke University
Smoking, Cigarette, Breastfeeding
Lung and Breast Cancer Prevention by an Integrated Intervention of Maternal Smoking Cessation and Breastfeeding
This pilot clinical trial aims to integrate maternal smoking cessation and breastfeeding interventions to enhance both cancer prevention behaviors.
- Trial name
- NCT05123118
- Testing
- Integrated intervention of smoking cessation and breastfeeding
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Xiaozhong Wen
Smoking During Pregnancy and Postpartum, Perinatal Cigarette Smoking
Smartphone-based Incentives Intervention to Increase Smoking Cessation During Pregnancy
Cigarette smoking is the leading preventable cause of poor pregnancy outcomes in the U.S. and a problem for which more effective and easy-to-access treatments are much needed.
- Trial name
- NCT07840118
- Testing
- Best Practices, Financial Incentives
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- University of Vermont
Schizophrenia, Tobacco Use Disorder
Varenicline Effects In Schizophrenic Smokers
This is an open label pre-post study of the effects of clinical treatment with varenicline on 1) decreasing smoking in schizophrenic patients, 2) improving selected cognitive measures in schizophrenic patients, and 3)…
- Conditions
- Schizophrenia, Tobacco Use Disorder, Nicotine Dependance
- Trial name
- NCT00548470
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Nathan Kline Institute for Psychiatric Research
Tobacco Use Disorder
Innovative Interventions for Smoking Cessation
The purpose of this study is to evaluate the effect of a combination of the 21 mg nicotine patch and very low nicotine content (VLNC) cigarettes compared to 21 mg nicotine patch only and very low nicotine content cigarette only…
- Trial name
- NCT01050569
- Testing
- Nicotine Patch, VLNC Cigarette, VLNC Cigarette Plus Nicotine Patch
- Where
- 2 sites in United States
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cigarette Smoking, Addiction Nicotine
Investigation of Cigarette Cravings in Smokers
Interventions to disrupt memory reconsolidation have held promise for the treatment of stress- and anxiety-related disorders. In the present study, the investigators will examine whether an intervention based on these principles…
- Conditions
- Cigarette Smoking, Addiction Nicotine, Tobacco Use
- Trial name
- NCT04843969
- Testing
- Stress induction, Control stress exposure, Cue induction
- Where
- Canada
- Volunteers
- 76 people
- Sponsor
- Marco Leyton
Electronic Cigarette
Nicotine Pharmacokinetic in Blood and Analysis of Exhaled Breath After E-cigarette Smoking.
Electronic or e-cigarettes are battery-powered devices that deliver vapor which may be inhaled in the manner tobacco is smoked. The e-liquid is usually a solution containing propylene glycol and/or vegetable glycerin, nicotine…
- Trial name
- VAPexp'Air (NCT03573154)
- Testing
- administration of the liquid 1 and then the liquid 2, administration of the liquid 2 and then the liquid 1
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Smoking, Smoking Cessation
Hollings Cancer Center Varenicline Sampling Study
The purpose of this study is to learn what happens when people are given a free, 4-week, sample of varenicline, a smoking cessation medication.
- Conditions
- Smoking, Smoking Cessation, Smoking, Tobacco, Smoking, Cigarette
- Trial name
- NCT03742154
- Testing
- Varenicline 0.5 MG
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Medical University of South Carolina