Clinical trials: Smoking Abstinence
Smoking Cessation
Comparison of Efficacy and Safety of Rimonabant 5mg/Day or 20mg/Day Versus Placebo in Smoking Cessation
The primary objective is to assess the efficacy of 2 fixed doses of rimonabant versus placebo on abstinence from tobacco use in cigarette smokers.
- Trial name
- STRATUS-EU (NCT00464165)
- Testing
- rimonabant
- Where
- 7 sites in Belgium, Denmark and 5 more
- Volunteers
- 789 people
- Sponsor
- Sanofi
Nicotine Dependence, Nicotine Addiction
Effectiveness of N-Acetylcysteine (NAC) in Motivational Enhancement Therapy for Nicotine Addiction
The goal of this clinical trial is to determine the effectiveness of the combination of n-acetylcysteine and motivational enhancement therapy on laboratory improvement in the form of changes in blood nicotine, radiological…
- Trial name
- NCT05903014
- Testing
- n-acetylcysteine, Motivational Enhancement Therapy
- Where
- Indonesia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Smoking Cessation
Smoking Cessation: Financial Incentives
The aim of this intervention is to test if the investigator, by offering a financial incentive to smokers who abstinence from smoking, can: 1.
- Trial name
- NCT03849092
- Testing
- Financial incentives, Campaigns
- Where
- Denmark
- Volunteers
- 1,934 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Smoking Cessation
Spanish-Language Smoking Cessation Trial
Results of a recently completed National Cancer Institute (NCI) funded trial of an intervention, Forever Free: Stop Smoking for Good, revealed high efficacy throughout the 24- month follow-up period, further supporting the…
- Trial name
- NCT02945787
- Testing
- Spanish-Language Version of the Stop Smoking for Good, NCI-Produced Spanish-language Self-help Booklet
- Where
- United States
- Volunteers
- 1,417 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Smoking
Neuroimaging Attentional Impairment During Abstinence
The broad objective of this proposal is to identify functional neuroanatomical correlates of impairments in sustained attention during smoking abstinence.
- Trial name
- SmokeAtt01 (NCT00692406)
- Testing
- Smoking Abstinence
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Duke University
Smoking
The Compliance of Varenicline With Short-massage
Research indicated that the relapse rate of smokers who attempted to give up smoking without drug and other assistance is up to 90-95% while the successful cessation rate may be improved a lot with assistance to quit smoking.
- Trial name
- CV-SM (NCT01656083)
- Where
- Germany
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- yu hong xia
Smoking Cessation
Building Capacity and Promoting Smoking Cessation in the Community Via "Quit to Win" Contest 2019
The present study will examine (1) effectiveness of a combined intervention of AWARD advice, active referral, instant messaging and optional cocktail intervention to increase abstinence using a sequential multiple assignment…
- Trial name
- NCT03992742
- Testing
- Initial phase: personalized instant messaging (PIM), Second phase: optional cocktail interventions (OCI), Initial phase: regular instant messaging (RIM)
- Where
- Hong Kong
- Volunteers
- 1,200 people
- Sponsor
- The University of Hong Kong
Cigarette Smoking, Tobacco Use
Gabapentin for Smoking Cessation
Gabapentin is an anti-epileptic agent that has shown preliminary evidence of efficacy for improving symptoms of cocaine and alcohol withdrawal in pilot studies.
- Trial name
- NCT00578552
- Testing
- Gabapentin - 1800 mg/day, Gabapentin - 2700 mg/day
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Smoking ( Cigarette), Smoking (Tobacco) Addiction
Smoking Cessation With Wearables to Improve General, Oral Health and Quality of Life
Tobacco smoking remains one of the leading preventable causes of disease, disability, and premature death worldwide. According to the World Health Organization, tobacco use is responsible for more than eight million deaths each…
- Conditions
- Smoking ( Cigarette), Smoking (Tobacco) Addiction, Smoking Behaviors, Smoking Cessation
- Trial name
- Wear-Smile (NCT07593742)
- Testing
- Telemedicine-Based Smoking Cessation Program, Conventional Smoking Cessation Behavioral Program
- Volunteers
- 102 people
- Sponsor
- University of Salerno
Nicotine Dependence
The Effects of Craving and Abstinence From Cigarettes on Brain Metabolism in Smokers
Craving and withdrawal from smoking cigarettes are major factors for relapse. We investigated craving for cigarettes in smokers undergoing pharmacological treatment with Bupropion (Zyban).
- Trial name
- NCT00267813
- Testing
- Bupropion (Zyban)
- Where
- Israel
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Tobacco Use Disorder
Abstinence Reinforcement Therapy for Veterans Who Smoke Tobacco and Are Experiencing Homelessness
Seventy to eighty percent of Veterans experiencing homelessness (VEH) smoke, which is four times the rate of the U.S. population and 2.5 times higher than among impoverished Americans.
- Trial name
- New HART (NCT07714200)
- Testing
- Cognitive Behavioral Therapy for Smoking Cessation, Nicotine Replacement Therapy, Bupropion
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- VA Office of Research and Development
Smoking Abstinence
Effects of AFQ056 and Nicotine in Reducing Cigarette Smoking
The purpose of this study is to assess the safety and efficacy of AFQ056 and nicotine compared to placebo on craving and withdrawal symptoms during voluntary smoking stoppage in healthy smokers.
- Trial name
- NCT00414752
- Testing
- AFQ065
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Novartis
Addiction
Progressive Muscle Relaxation and Cigarette Craving
Cigarette craving usually occurs with unpleasant feelings, including stress. Progressive Muscle Relaxation (PMR) may reduce level of cigarette craving and/or withdrawal symptoms.
- Trial name
- NCT02153775
- Testing
- Progressive Muscle Relaxation
- Where
- Thailand
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Tobacco Use Cessation, Pregnancy Related
Pilot Trial of Using SmokeBeat to Monitor and Increase Smoking Abstinence in Pregnant Women
Investigators will assess the feasibility of implementing a randomized control trial of a behavioral intervention that uses smartwatch technology to monitor smoking behavior with texts aimed at reducing smoking in pregnant women…
- Trial name
- NCT03209557
- Testing
- SmartWatch SmokeBeat Application
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Smoking Cessation
A Second Study of NicVAX/Placebo as an Aid for Smoking Cessation
The purpose of this study is to evaluate NicVAX as an aid to smoking cessation for long term abstinence.
- Trial name
- NCT01102114
- Testing
- NicVAX Vaccine
- Where
- 25 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Nabi Biopharmaceuticals
Cerebral Oxygenation and Blood Flow in Tobacco Use Disorder
Investigation of Brain Oxygenation and Blood Flow in Smokers
Cerebral oxygenation and blood flow in tobacco use disorder and their relation to smoking abstinence will be measured with MRI" ändern in "Cerebral oxygenation and blood flow in tobacco use disorder
- Trial name
- OEF (NCT03571243)
- Testing
- no intervention
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim
Tobacco Use Cessation
Mobile Media-Rich Interactive Guideline System (MMRIGS) Pilot Study
The goal of this research study is to learn about 2 different interactive methods that are designed to help people with HIV/AIDS stop smoking.
- Trial name
- NCT02302859
- Testing
- Nicotine Patch, Questionnaires, Pamphlet
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Smoking Cessation
Not Quite Ready to Quit
In our communications with the public, the investigators will call this the Not Quite Ready to Quit Smoking Study. One new method to increase quit attempts is to have smokers reduce their cigs/day.
- Trial name
- NCT01866722
- Testing
- Usual care, Reduction, 5Rs
- Where
- United States
- Volunteers
- 560 people
- Sponsor
- University of Vermont
Tobacco Use Cessation
Quit IT: Preliminary Testing of a Web-based, 3D Coping Skills Game to Increase Quitting Self-Efficacy for Maintaining Smoking Abstinence Following Hospitalization
The purpose of this study is to develop and test a web-based game called Quit It that is designed to help smokers who have quit smoking cope with any smoking urges they may have.
- Trial name
- NCT02099097
- Testing
- web-based video game (Quit IT), Questionnaires, Salvia sample
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Memorial Sloan Kettering Cancer Center