Clinical trials: Smoking Behavior, open to volunteers
Small Airways Diseases, Vaping
The Canadian Lung Outcomes in Users of Vaping Devices Study
Vaping is increasingly popular with both adolescent and adult Canadians, but the long-term health impacts remain unknown. We believe that the tools we currently have to detect lung disease in people who vape may be insufficient…
- Conditions
- Small Airways Diseases, Vaping, Vaping Related Disorder, Vaping Teens
- Trial name
- CLOUD (NCT06819969)
- Where
- 8 sites in Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
HIV Infections, Tuberculosis
South Africa Smoking Cessation and Engagement in HIV/TB Care Care
The purpose of this study is to integrate elements from existing interventions developed by our team into a single intervention (QUIT-AD), designed to improve smoking cessation and favorable HIV/TB treatment outcomes among…
- Conditions
- HIV Infections, Tuberculosis, Smoking Cessation
- Trial name
- NCT05842161
- Testing
- QUIT-AD, Enhanced Treatment as Usual
- Where
- South Africa
- Volunteers
- 83 people
- Sponsor
- Massachusetts General Hospital
Smoking, Smoking Cessation
Technology Assisted Motivational Interviewing
Building on our successful pilot work to develop a Motivational Interviewing (MI)-capable chatbot and cessation coach, the investigators propose to address the problems of intrinsic motivation and social barriers to smoking…
- Trial name
- TAMI (NCT06713603)
- Testing
- TAMI Coach
- Where
- 2 sites in United States
- Volunteers
- 440 people
- Sponsor
- University of California, San Francisco
Acute Coronary Syndrome, Cardiovascular Diseases
Aggressive Smoking Cessation Trial (ASAP)
The ASAP Trial is a 5-year, multi-centre, randomized controlled trial that will assess the efficacy, safety, and tolerability of aggressive smoking cessation therapy among people at elevated cardiovascular risk.
- Trial name
- ASAP (NCT05257629)
- Testing
- Combination Therapy Arm (Varenicline and Nicotine E-Cigarettes Plus Counseling), Varenicline Plus Counseling
- Where
- 13 sites in Canada
- Volunteers
- 798 people
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Chronic Obstructive Pulmonary Disease, Pulmonary Hypertension
Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH
The investigators will study whether the drug tadalafil improves shortness of breath in 126 Veterans with Chronic Obstructive Pulmonary Disease (COPD) and high blood pressure in the lungs.
- Conditions
- Chronic Obstructive Pulmonary Disease, Pulmonary Hypertension, Dyspnea
- Trial name
- BETTER COPD-PH (NCT05937854)
- Testing
- Tadalafil
- Where
- 5 sites in United States
- Volunteers
- 126 people
- Sponsor
- VA Office of Research and Development
Lung Cancer, Protection Against Malignant Lung Neoplasm (Diagnosis)
Cancer Screening Smoking Cessation AND Respiratory Assessment
The CASSANDRA project (Cancer Screening, Smoking Cessation, AND Respiratory Assessment) is a project led by SEPAR whose main coordinators are Dr. Luis Seijo, a pulmonologist at the Clínica Universitaria de Navarra, and Dr.
- Trial name
- CASSANDRA (NCT06157957)
- Testing
- Lung cancer screening with low dose CT scan
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Tobacco Cessation, Health Warning Label
Health Warnings and Counseling for Smoking Cessation
Tobacco use remains persistently high across South Asia, despite numerous public health efforts, and continues to significantly contribute to the burden of non-communicable diseases (NCDs) such as cardiovascular disease…
- Conditions
- Tobacco Cessation, Health Warning Label, Hypertension, Non Communicable Chronic Diseases
- Trial name
- NCT07098065
- Testing
- Graphical health warnings, Graphical health warnings plus pharmacist-led counselling, Routine pharmacy services (no intervention)
- Where
- Bangladesh
- Volunteers
- 3,400 people
- Sponsor
- Hitotsubashi University
Postpartum Period, Smoking Relapse Behavior
The Effect of Motivational Interviewing and Digital Game-Supported Counseling on Postpartum Relapse
This randomized controlled trial aims to determine the effect of motivational interviewing-based, digital game-supported counseling on postpartum smoking relapse among pregnant women who quit smoking spontaneously during…
- Trial name
- NCT07271953
- Testing
- Motivational Interviewing and Digital Game-Supported Counseling, Routine Antenatal Care
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Lokman Hekim University
Smoking, Smoking Cessation
A Study Evaluating the Use of an Indoor Air Quality Monitor to Promote a Smoke-free Home
The purpose of this study is to evaluate how using an indoor air quality monitor can promote a smoke-free home for cancer patients who are enrolled in MSK's Tobacco Treatment Program.
- Conditions
- Smoking, Smoking Cessation, Smoking Reduction, Smoking Habit
- Trial name
- NCT06693700
- Testing
- Indoor Air Quality Monitor AirGradient ONE
- Where
- 8 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
E-cigarette Use, Withdrawal
Evaluation of the Electronic Cigarette Withdrawal Syndrome
The goal of this project is to rigorously evaluate the nature of e-cigarette withdrawal in exclusive e-cigarette users during a monitored abstinence period and the role of nicotine in the expression of this withdrawal syndrome.
- Trial name
- NCT06066996
- Testing
- Transdermal Nicotine Patch
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
E-cigarette Use, Vaping
A Trial of Varenicline for E-cigarette Cessation
This is randomized, placebo-controlled clinical trial in treatment-seeking adults who report regular e-cigarette use to test the hypothesis that varenicline is efficacious for quitting e-cigarettes.
- Conditions
- E-cigarette Use, Vaping, Nicotine Dependence
- Trial name
- NCT07040566
- Testing
- Varenicline 1mg BID
- Where
- 2 sites in United States
- Volunteers
- 326 people
- Sponsor
- Yale University
Nicotine Dependence, E-cigarette Use
Sex Differences in E-Cigarette Perception
This study examines differences between males and females in the appeal and addiction potential of menthol flavored e-cigarettes with and without nicotine.
- Trial name
- NCT07398976
- Testing
- Nicotine Level 1 (0mg/ml), Nicotine Level 2 (36mg/ml), Nicotine Level 3 (59mg/ml)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yale University
Smoking Cessation
Mindfulness-based Ecological Momentary Intervention for Smoking Cessation Among Cancer Survivors
The purpose of the study is to develop a new quit-smoking treatment among individuals with a cancer diagnosis using a smartphone app.
- Trial name
- NCT07210567
- Testing
- Mindfulness, Quitline
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Rutgers, The State University of New Jersey
Hypertension, Tobacco Cigarette Smoking
Cardiovascular Impacts of E-cigarettes Among Older Adults
This study will compare the cardiovascular effects of continued smoking with those of e-cigarette (EC) use among older adults with hypertension.
- Conditions
- Hypertension, Tobacco Cigarette Smoking, Electronic Cigarettes, Cardiovascular
- Trial name
- NCT07880704
- Testing
- Nicotine E-cigarette, Tobacco Cigarette
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Maryland, Baltimore
Peri-Implant Health, Peri Implant Mucositis
Impact of Smoking on Immune Responses in Peri-implant Health and Disease
Peri-implant diseases are inflammatory conditions affecting the gums and bone around dental implants. Peri-implant mucositis causes inflammation in the gums, while peri-implantitis can also lead to bone loss and, in severe cases…
- Conditions
- Peri-Implant Health, Peri Implant Mucositis, Peri-implantitis
- Trial name
- NCT07750171
- Where
- Turkey (Türkiye)
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Gazi University
Cigarette Smoking, Nicotine Dependence
Evaluation of Low and High Nicotine Tobacco Free Nicotine Pouches
Tobacco-free oral nicotine pouches (such as Zyn brand) are a less harmful alternative to cigarette smoking. Pouches, however, contain nicotine, and addictive substance that is not risk-free.
- Conditions
- Cigarette Smoking, Nicotine Dependence, Smoking Cessation
- Trial name
- Pack2Pouch (NCT06678789)
- Testing
- High Nicotine Dose, Low Nicotine Dose
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina