Clinical trials: Smoking Cessation
Smoking Cessation
Study Evaluating The Safety And Efficacy Of Varenicline and Bupropion For Smoking Cessation In Subjects With And Without A History Of Psychiatric Disorders
This study is being conducted to assess varenicline and bupropion as aids to smoking cessation treatment in subjects with and without an established diagnosis of major psychiatric disorder and to characterize the neuropsychiatric…
- Trial name
- EAGLES (NCT01456936)
- Testing
- varenicline tartrate, bupropion hydrochloride, Nicotine Replacement Therapy Patch
- Where
- 156 sites in United States, Argentina and 14 more
- Volunteers
- 8,144 people, healthy volunteers welcome
- Sponsor
- Pfizer
Smoking Cessation
A Second Study of NicVAX/Placebo as an Aid for Smoking Cessation
The purpose of this study is to evaluate NicVAX as an aid to smoking cessation for long term abstinence.
- Trial name
- NCT01102114
- Testing
- NicVAX Vaccine
- Where
- 25 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Nabi Biopharmaceuticals
Smoking, Tobacco Use Disorder
QuitAdvisorMD: A Point-of-care Tool for Brief Smoking Cessation Interventions
QuitAdvisorMD: A point-of-care tool for brief smoking cessation interventions Under a Phase II SBIR grant supported by NIH/NIDA, we are developing QUITAdvisorMD: a point-of-care, patient-centered resource for counseling patients…
- Trial name
- NCT01065493
- Testing
- QuitAdvisorMD Software Algorithm, Standard Smoking Cessation Counseling
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Silverchair Science & Communications, LLC
Smoking Cessation
Studying NMDA and Sigma-1 in Smoking Cessation Treatment (SUMMIT)
This study is a Phase 3, multicenter, randomized, double-blind, placebo- and active-controlled, parallel-group trial to evaluate the efficacy and safety of AXS-05 compared to placebo and bupropion for smoking cessation in adults.
- Trial name
- SUMMIT (NCT07766655)
- Testing
- AXS-05 (dextromethorphan-bupropion), Bupropion
- Where
- 26 sites in United States
- Volunteers
- 705 people
- Sponsor
- Axsome Therapeutics, Inc.
Smoking Cessation
A Single Dose-escalation Study of Cytisine in Adult Smokers
The objectives of this study are: 1. To assess the tolerability and safety of cytisine as a single oral dose. 2. To define the Cmax levels associated to the occurrence of dose-limiting adverse events.
- Trial name
- NCT03848208
- Testing
- cytisine
- Where
- Portugal
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Achieve Life Sciences
Smoking
Efficacy and Safety Study of Nicotine Mint Lozenge (2mg and 4mg) in Smoking Cessation
A multi-center, randomized, double-blind, placebo-controlled, 4-arm clinical study to evaluate efficacy and safety of nicotine lozenge (2mg and 4mg) in smoking cessation in adult cigarette smokers who are motivated to quit…
- Trial name
- NCT00985985
- Testing
- Nicotine
- Volunteers
- 723 people
- Sponsor
- GlaxoSmithKline
Smoking, Smoking Cessation
Evaluation of the Nicotine Lozenge in Relief of Provoked Acute Craving
This study is designed to evaluate the ability of a nicotine lozenge to relieve craving for a cigarette compared to a matched placebo (a placebo is like sugar pill and contains no active).
- Trial name
- NCT01466361
- Testing
- Nicotine lower dose, Nicotine higher dose
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- GlaxoSmithKline
Depressive Disorder, Major
A 7-year Assessment on Subject Understanding of ZYBAN/ WELLBUTRIN Associated Risks
Branded bupropion hydrochloride products including ZYBAN and WELLBUTRIN range are approved for the treatment of smoking cessation and depressive disorders respectively.
- Trial name
- NCT03001440
- Testing
- KAB survey
- Volunteers
- 1 people
- Sponsor
- GlaxoSmithKline
Smoking Cessation, Smoking, Tobacco
Pivot Breath Sensor Human Factors and Usability Study
Prospective, observational open label, single center study enrolling up to 15 subjects to evaluate human factors and usability of the Pivot Breath Sensor.
- Trial name
- NCT03835260
- Testing
- Pivot Breath Sensor
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Jennifer Marler, MD