Clinical trials: Smoking Cessation, completed
Tobacco Use Disorder
Financial Incentives for Smoking Cessation
The purpose of this study is to test the effectiveness of financial incentives for increasing long-term smoking cessation rates among employees at General Electric worksites throughout the United States.
- Trial name
- NCT00128375
- Testing
- Financial incentives
- Where
- United States
- Volunteers
- 878 people
- Sponsor
- University of Pennsylvania
Smoking Cessation
A 52-Week Placebo-Controlled Study Evaluating the Safety of Varenicline
The primary purpose of this study is to obtain safety information on cigarette smokers treated with 52 weeks of varenicline regardless of smoking status.
- Trial name
- NCT00143299
- Testing
- varenicline (CP-526,555)
- Where
- 9 sites in United States, Australia
- Volunteers
- 375 people
- Sponsor
- Pfizer
Smoking Cessation, Smoking, Cigarette
Enhancing Self Regulation Among Smokers
The purpose of this study is to examine the effects of rapamycin (sirolimus) versus a placebo, an inactive substance, on responses to smoking cues in individuals with nicotine dependence.
- Conditions
- Smoking Cessation, Smoking, Cigarette, Nicotine Dependence
- Trial name
- MIMIC (NCT04161144)
- Testing
- sirolimus
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Medical University of South Carolina
Smoking Cessation, Second Hand Tobacco Smoke
Smoke-free Home Intervention in Permanent Supportive Housing
The focus of this study is on expanding access to voluntary smoke-free homes to formerly homeless residents residing in permanent supportive housing and examining the impact of this intervention on reducing tobacco-caused…
- Trial name
- NCT04855357
- Testing
- Resident counselling, Staff Training
- Where
- United States
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Tobacco Use Disorder
Framing Messages for Smoking Cessation With Bupropion - 6
This is a randomized study of message framing in individuals beginning a smoking cessation program utilizing bupropion SR and brief counseling, videos, and pamphlets.
- Trial name
- NCT00104598
- Testing
- Bupropion, Smoking Abstinence Program
- Where
- United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Yale University
Substance Use Disorder (SUD), Alcohol Use Disorder (AUD)
Metabolome and Gut Microbiome Changes During Smoking Cessation in Long-term Drug Therapy in a Therapeutic Community
Theoretical Framework: Cigarette smoking is the leading preventable cause of death worldwide, with nicotine dependence notably common among individuals with Substance Use Disorders (SUD).
- Conditions
- Substance Use Disorder (SUD), Alcohol Use Disorder (AUD), Nicotine Addiction, Healthy Adult Participants
- Trial name
- NCT06803706
- Testing
- 6-weeks CBT smoking cessation programme, Long-term drug therapy within a therapeutic community
- Where
- 3 sites in Austria
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Sigmund Freud PrivatUniversitat
Smoking Cessation, Alcohol-Related Disorders
Effectiveness of Bupropion for Smokers Recovering From Alcohol Dependence
Smoking is often a problem for alcohol dependent individuals. Many people who seek treatment for alcohol dependence are unable to quit smoking.
- Trial name
- NCT00304707
- Testing
- Bupropion
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Smoking Cessation, Marijuana Use
Project CheckUP: A Brief Behavioral Intervention for Quitline Callers Who Use Marijuana (MJ) and Tobacco
Smoking cigarettes remains the number one preventable cause of death and disease in the US. Smokers who call tobacco quitlines and use marijuana struggle to quit tobacco due to the interactive effects of nicotine and marijuana.
- Trial name
- NCT04737772
- Testing
- Behavioral: Quitline treatment as usual, QL Marijuana Check-Up intervention (QL-MJCU)
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Consumer Wellness Solutions
Tobacco Dependence
Provider and Peer Delivered Youth Smoking Intervention
The purpose of this study was to determine whether a pediatric practice-based smoking prevention and cessation intervention increases abstinence rates among adolescents.
- Trial name
- NCT00435344
- Testing
- Pediatric Practice-Based Smoking Intervention
- Where
- United States
- Volunteers
- 2,711 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Smoking Cessation
Patient Navigation and Financial Incentives to Promote Smoking Cessation
Cigarette smoking is a significant health threat. To eliminate disparities in cancer burden, smoking rates must be reduced among populations where smoking is disproportionately concentrated: those with low socioeconomic status…
- Trial name
- NCT02351609
- Testing
- Intervention, Enhanced Traditional Care control
- Where
- United States
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Lung Cancer - Non Small Cell Squamous
Comparison of Longer-term (5 Year+) Outcomes (Survival) of Smokers, Ex-smokers, Never Smoker and Quitters
Between 2010-2020, the LungCAst observational study followed 3700 patients newly diagnosed with lung cancer across 33 hospitals in Wales and England for 2 years to see if smoking status at time of diagnosis predicted survival…
- Trial name
- LungCast2 (NCT07127263)
- Where
- United Kingdom
- Volunteers
- 525 people
- Sponsor
- Hywel Dda Health Board
Schizoaffective Disorder, Schizophrenia
Smoking Cessation for Veterans With Severe and Persistent Mental Illness
The investigators have developed an intervention called Behavioral Treatment of Smoking Cessation in SPMI (BTSCS), an innovative intervention that supplements pharmacotherapy and education with contingency management and a…
- Conditions
- Schizoaffective Disorder, Schizophrenia, Affective Psychosis, Bipolar, Affective Disorders, Psychotic
- Trial name
- NCT00960375
- Testing
- BTSCS, StSST
- Where
- 2 sites in United States
- Volunteers
- 179 people
- Sponsor
- US Department of Veterans Affairs
Nondaily Smoking
A Proof-of-concept RCT of Version 3.0 of the Smoking Cessation Smartphone App "Smiling Instead of Smoking" (SiS)
This is the third study in a series of 3 studies to develop a smartphone app to support nondaily smokers in quitting smoking, as funded by the American Cancer Society grant #RSG CPPB - 130323 (project dates: 07/01/2017 …
- Trial name
- NCT04672239
- Testing
- Smartphone app "Smiling instead of Smoking" (SiS) Version 3, Smartphone app "QuitGuide" (QG), Brochure "Clearing the Air" (CTA)
- Where
- United States
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Stroke
Cost Free Pharmacotherapy for Smoking Cessation in Stroke Patients
This pilot study examined the effect of providing a 4 weeks of cost free quit smoking medications to smokers identified in a stroke prevention clinic who were interested in quitting smoking compared to providing a prescription…
- Trial name
- NCT01404546
- Testing
- cost free pharmacotherapy, usual care
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Smoking Cessation
Women Engaging in Quitting Smoking Together
The long-term goal of this program of research is to develop and disseminate an efficacious, group-based distress tolerance treatment for weight concern (DT-W) that will significantly increase smoking cessation rates among women.
- Trial name
- WE QUIT (NCT02453659)
- Testing
- Distress Tolerance Treatment for Weight Concern (DT-W), Health Education (HE), Smoking Cessation counseling
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rhode Island Hospital
Cigarette Smoking, Smoking Cessation
Goal2Quit + NRT Sampling
The goal of this work is to develop, systematically evaluate, and clinically test an integrated cessation intervention comprised of a depression-specific Behavioral Activation (BA) for cessation mobile app ("Goal2Quit") packaged…
- Conditions
- Cigarette Smoking, Smoking Cessation, Depression
- Trial name
- NCT03837379
- Testing
- Treatment as Usual, Goal2Quit + NRT Sampling
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Medical University of South Carolina
Human Immunodeficiency Virus, Smoking Cessation
Effectiveness of an Integrated Treatment to Address Smoking Cessation and Anxiety/ Depression in People Living With HIV
Smokers living with HIV represent a major health disparity population in the United States and the world more generally. Major contributing factors to the maintenance and relapse of smoking among smokers living with HIV include…
- Conditions
- Human Immunodeficiency Virus, Smoking Cessation, Smoking, Cigarette, Smoking
- Trial name
- NCT03904186
- Testing
- QUIT, Time-Matched Control (TM)
- Where
- 3 sites in United States
- Volunteers
- 131 people
- Sponsor
- Massachusetts General Hospital
Smoking Cessation, Tobacco Use Cessation
Safety and Effectiveness of NicVAX in Treating Nicotine Dependent Individuals
Nicotine is highly addictive and many individuals are unable to quit smoking even with treatment. The purpose of this study is to determine the effectiveness of various doses of NicVAX in treating nicotine dependent individuals.
- Trial name
- NCT00218413
- Testing
- NicVAX
- Where
- Netherlands
- Volunteers
- 51 people
- Sponsor
- Nabi Biopharmaceuticals
Smoking
Feasibility and Acceptability of a Text Messaging Intervention to Increase Smoking Cessation in Vietnam
The purpose of this study is to develop and then test the feasibility, acceptability, and preliminary effect of a bidirectional text message smoking cessation intervention among Vietnamese smokers in Hanoi, Vietnam.
- Trial name
- NCT03219541
- Testing
- Interventional Automated mobile phone text, Control Automated mobile phone text
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Tobacco Use Disorder, Smoking
Distribution of Bupropion and Varenicline to Increase Smoking Cessation Attempts
Bupropion and varenicline are indicated for smoking cessation. The objectives of this study are two-fold: (1) to explore the logistic feasibility of distributing bupropion and varenicline free of charge to treatment-seeking…
- Conditions
- Tobacco Use Disorder, Smoking, Smoking Cessation
- Trial name
- NCT01023659
- Testing
- bupropion, varenicline, motivational emails
- Where
- Canada
- Volunteers
- 893 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
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