Clinical trials: Smoking Cessation
Mental Illness, Tobacco Smoking
Decision Support for Smoking Cessation in Young Adults With Severe Mental Illness
Up to 77% of young people with severe mental illnesses smoke, a rate that is up to five times higher than the rate of daily smoking in other young adults.
- Conditions
- Mental Illness, Tobacco Smoking, Psychotic Disorders
- Trial name
- NCT01779440
- Testing
- Electronic Decision Support System
- Where
- 3 sites in United States
- Volunteers
- 58 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Carcinoma In Situ, Current Smoker
Implementing a Virtual Tobacco Treatment for Cancer Patients in Community Oncology Practices
This phase II trial studies how well smoking cessation treatment plans work in tobacco-dependent cancer patients when delivered virtually as part of their cancer care in community oncology practices.
- Conditions
- Carcinoma In Situ, Current Smoker, Malignant Neoplasm, Primary Neoplasm
- Trial name
- NCT03808818
- Testing
- Behavioral, Psychological or Informational Intervention, Nicotine Replacement, Quality-of-Life Assessment
- Where
- 42 sites in United States
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- ECOG-ACRIN Cancer Research Group
Tobacco Use Cessation, Smoking Cessation
Treating Low-Income Smokers in the Hospital Emergency Department
This study will test the effectiveness of an Emergency Department (ED) initiated tobacco intervention which includes counseling and medication.
- Conditions
- Tobacco Use Cessation, Smoking Cessation, Smoking, Tobacco Use Disorder
- Trial name
- NCT01328431
- Testing
- Brief Intervention with NRT Initiation
- Where
- United States
- Volunteers
- 780 people
- Sponsor
- Yale University
Smoking Cessation, HIV
Patch Study - Intervention for HIV Positive Smokers
The overall objective of the transdisciplinary team of Human Immunology Virus (HIV) and Tobacco funded researchers is to test if tailoring nicotine replacement doses to temper these excessive levels will enhance the efficacy of…
- Trial name
- NCT02982772
- Testing
- Combination Therapy, Standard Care Intervention
- Where
- United States
- Volunteers
- 488 people
- Sponsor
- dr. maria miguez
Smoking, Nicotine Dependence
Placebo-controlled Trial of Bupropion for Smoking Cessation in Pregnant Women
Smoking during pregnancy adversely affects the health of the mother and her developing baby. Maternal smoking approximately doubles the risk of miscarriage, placental complications, preterm delivery, low birth weight and fetal…
- Trial name
- BIBS (NCT02188459)
- Testing
- Bupropion
- Where
- 3 sites in United States
- Volunteers
- 129 people
- Sponsor
- Henry Kranzler
Cancer of Head and Neck, Breast Cancer
Brain Stimulation For Cancer Smokers
Smoking cessation and relapse prevention represent and important opportunity to improve cancer survival rates, reduce the risk of cancer treatment complication, and improve the quality of life of patients with and survivors of…
- Conditions
- Cancer of Head and Neck, Breast Cancer, Prostate Cancer, Nicotine Dependence
- Trial name
- NCT03419741
- Testing
- Transcranial Magnetic Stimulation Clinical Research System
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Medical University of South Carolina
Smoking, Smoking Cessation
Evaluation of the Nicotine Lozenge in Relief of Provoked Acute Craving
This study is designed to evaluate the ability of a nicotine lozenge to relieve craving for a cigarette compared to a matched placebo (a placebo is like sugar pill and contains no active).
- Trial name
- NCT01466361
- Testing
- Nicotine lower dose, Nicotine higher dose
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- GlaxoSmithKline
Pulmonary Disease, Chronic Obstructive, Cigarette Smoking
E-Visit for COPD and Smoking Cessation
The goal of this work is to develop, refine, and pilot test an electronic visit (e-visit) to: 1) deliver smoking cessation treatment to adults at risk for COPD and 2) to improve rates of COPD early detection and accurate…
- Conditions
- Pulmonary Disease, Chronic Obstructive, Cigarette Smoking, Telemedicine
- Trial name
- NCT04155073
- Testing
- smoking cessation, early COPD detection, electronic visit, Treatment As Usual
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Medical University of South Carolina
Smoking Cessation, Harm Reduction
Combination of E-cigarettes and Varenicline for Tobacco Harm Reduction
This open-label study will explore the impact of varenicline on the process of switching from combustible cigarettes (CC) to an e-cigarette.
- Trial name
- EVAR (NCT04210180)
- Testing
- Varenicline, e-cigarette
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Rose Research Center, LLC
Smoking Cessation
Nicotine Replacement Therapy (NRT) Sampling and Selection to Increase Medication Adherence
To determine the preliminary impact on Nicotine Replacement Therapy (NRT)adherence and examine the underlying mechanisms of action associated with adherence.
- Trial name
- NRT (NCT03276780)
- Testing
- Counseling, combination NRT
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Alabama at Birmingham
Nondaily Smoking
A Proof-of-concept RCT of Version 3.0 of the Smoking Cessation Smartphone App "Smiling Instead of Smoking" (SiS)
This is the third study in a series of 3 studies to develop a smartphone app to support nondaily smokers in quitting smoking, as funded by the American Cancer Society grant #RSG CPPB - 130323 (project dates: 07/01/2017 …
- Trial name
- NCT04672239
- Testing
- Smartphone app "Smiling instead of Smoking" (SiS) Version 3, Smartphone app "QuitGuide" (QG), Brochure "Clearing the Air" (CTA)
- Where
- United States
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Smoking Cessation, Bipolar Disorder
Varenicline Treatment for Smoking Cessation in Patients With Bipolar Disorder
The investigators' hypothesis is that add-on varenicline will be effective (versus placebo) in initiating abstinence from smoking in subjects with stable, euthymic bipolar disorder who are motivated to quit smoking within four…
- Trial name
- BEST (NCT01010204)
- Testing
- Varenicline
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- K.N. Roy Chengappa
Smoking, Smoking Cessation
Evaluating a Telephone-Based Smoking Cessation Program Among People in the Military (The AFIII Study)
Rates of cigarette smoking in the military are high. Tobacco telephone quit lines are telephone-based services that provide information and guidance to people who want to quit smoking.
- Trial name
- AFIII (NCT00632411)
- Testing
- Nicotine Patch, Tobacco Quit Line Program
- Where
- 2 sites in United States
- Volunteers
- 1,298 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Smoking Cessation, Opioid Related Disorders
Smoking Cessation & Opioid Dependence Treatment Integration
The primary purpose of this study was to examine the feasibility of integrating a smoking cessation intervention for cigarette smokers enrolled in an outpatient program for opioid dependence.
- Trial name
- NCT02854800
- Testing
- varenicline
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- West Virginia University
Smoking Cessation
Testing the Integrated mHealth App Intervention "SiS-H"
The present study is a pilot randomized controlled trial (RCT) that seeks to test the feasibility, acceptability, process outcomes, and exploratory outcomes of a newly integrated, app-based smoking cessation treatment (SiS-H…
- Trial name
- NCT05886621
- Testing
- Smiling instead of Smoking - HIV, QuitGuide
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Massachusetts General Hospital
Tobacco Use Disorder, Smoking Cessation
Mechanisms of Lorcaserin for Smoking Cessation
Identifying new medication options is critical for curbing the health burdens of cigarette smoking. Currently approved smoking cessation medications act on nicotinic receptors, and additional work is needed to identify…
- Trial name
- NCT04396834
- Testing
- Lorcaserin Oral Tablet
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- The Mind Research Network
Smoking
Aim 1: App for Reducing Cravings to Smoke
The aim of this study is to update a recently developed study-related smartphone application to reduce cravings to smoke to be an engaging, user-friendly treatment tool, and verify user satisfaction
- Trial name
- NCT06923033
- Testing
- Smartphone App
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Tobacco Use Disorder, Smoking Cessation
Pharmacogenetics, Emotional Reactivity and Smoking
The goals of this placebo-controlled randomized clinical trial were to evaluate the differences in emotional reactivity (peak startle response to affective stimuli) during a cessation attempt among smokers treated with bupropion…
- Trial name
- NCT00507728
- Testing
- Bupropion, Varenicline, Smoking Cessation Counseling
- Where
- United States
- Volunteers
- 646 people
- Sponsor
- M.D. Anderson Cancer Center
Cigarette Smoking
iQuit Mindfully: Text Messaging for Smoking Cessation
The purpose of this study is to investigate text messaging as a way to enhance mindfulness-based treatment for smoking cessation.
- Trial name
- NCT03029819
- Testing
- Mindfulness-based Addiction Treatment, iQuit Mindfully, Self-Help guide
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Georgia State University
Cigarette Smoking, Schizophrenia
Integrated Smoking Cessation Treatment for Smokers With Serious Mental Illness
The overall aim of this study is to test the effect of academic detailing (i.e. provider-level educational intervention focused on evidence-based smoking cessation treatment for those with psychiatric illness) and community…
- Conditions
- Cigarette Smoking, Schizophrenia, Bipolar Disorder, Depressive Disorder, Major
- Trial name
- NCT02845440
- Testing
- Academic Detailing, Community Health Worker, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 1,165 people
- Sponsor
- Massachusetts General Hospital