Clinical trials: Smoking Cessation, completed
Vaping, Nicotine Dependence
Varenicline for Nicotine Vaping Cessation in Adolescents
The study will test the hypothesis that varenicline, when added to behavioral and texting support for vaping cessation, will improve vaping abstinence rates in adolescents dependent on vaped nicotine over placebo plus behavioral…
- Trial name
- ViVA (NCT05367492)
- Testing
- Double Blind Varenicline, QuitVaping, This Is Quitting
- Where
- United States
- Volunteers
- 261 people
- Sponsor
- Massachusetts General Hospital
Smoking Cessation
Treatment of Smoking Lapses and Relapses
Many smokers who try to stop smoking with nicotine medications (NM) such as gum, lozenge and patch, go back to smoking (i.e., a slip or lapse).
- Trial name
- NCT01807871
- Testing
- nicotine patch, experimental use, nicotine patch, labeled use
- Where
- United States
- Volunteers
- 701 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Schizophrenia, Schizoaffective Disorder
Varenicline Treatment in Alcohol and Nicotine Dependent Patients With Schizophrenia
The aim of the proposed pilot study is to find out whether varenicline (ChantixTM) treatment decreases alcohol use and smoking in patients with schizophrenia or schizoaffective disorder.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Alcohol Dependence, Nicotine Dependence
- Trial name
- NCT00727103
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- State University of New York - Upstate Medical University
Cigarette Smoking-Related Carcinoma
Avatar-Led Digital Therapeutic for Aiding Smoking Cessation in Sexual and Gender Minority Young Adults
This trial assesses the acceptability and preliminary efficacy of Empowered, Queer, Quitting, and Living (EQQUAL) smoking-cessation intervention for sexual and gender minority young adult smokers.
- Trial name
- NCT05847673
- Testing
- Online Smoking Cessation Intervention, Questionnaire Administration, Health Promotion and Education
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Smoking Cessation
Technology and Telephone-Based Smoking Cessation
The goal of the proposed project is to design and assess the acceptability and usability of a mobile technology and telephone-facilitated treatment to improve treatment engagement in adult smokers with posttraumatic stress…
- Trial name
- RAP Smoking (NCT03492645)
- Testing
- Telephone-and technology-facilitated treatment protocol, Office-based treatment protocol
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Lung Cancer, Tobacco Use Disorder
Feasibility of Delivering a Quitline Based Smoking Cessation Intervention in Cancer Patients
RATIONALE: Continued smoking after a cancer diagnosis has important health consequences beyond the risks associated with smoking in the general population.
- Conditions
- Lung Cancer, Tobacco Use Disorder, Breast Cancer, Colorectal Cancer
- Trial name
- NCT01434342
- Testing
- Nicotine Replacement Patch
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Wake Forest University Health Sciences
Tobacco Use Disorder
Evaluation of Oral Tobacco as a Harm Reduction Method for Smokers
Recently, tobacco companies have developed new oral tobacco products that are purportedly less harmful than conventional tobacco products.
- Trial name
- NCT00711100
- Testing
- Camel Snus, Marlboro Snus, Stonewall
- Where
- 2 sites in United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smoking Cessation
Study Evaluating The Safety And Efficacy Of Varenicline and Bupropion For Smoking Cessation In Subjects With And Without A History Of Psychiatric Disorders
This study is being conducted to assess varenicline and bupropion as aids to smoking cessation treatment in subjects with and without an established diagnosis of major psychiatric disorder and to characterize the neuropsychiatric…
- Trial name
- EAGLES (NCT01456936)
- Testing
- varenicline tartrate, bupropion hydrochloride, Nicotine Replacement Therapy Patch
- Where
- 156 sites in United States, Argentina and 14 more
- Volunteers
- 8,144 people, healthy volunteers welcome
- Sponsor
- Pfizer
Smoking Cessation, HIV
Patch Study - Intervention for HIV Positive Smokers
The overall objective of the transdisciplinary team of Human Immunology Virus (HIV) and Tobacco funded researchers is to test if tailoring nicotine replacement doses to temper these excessive levels will enhance the efficacy of…
- Trial name
- NCT02982772
- Testing
- Combination Therapy, Standard Care Intervention
- Where
- United States
- Volunteers
- 488 people
- Sponsor
- dr. maria miguez
Smoking Cessation, Pregnancy
Bupropion for Smoking Cessation in Pregnancy
The purpose of this study is to determine whether bupropion SR increases cessation and/or smoking reduction among pregnant smokers.
- Trial name
- NCT01875172
- Testing
- Bupropion SR, smoking cessation counseling
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Watching Over Mothers & Babies Foundation
Nicotine Dependence
A Smoking Cessation Treatment for Adult Women
The purpose of this study is to develop and pilot test a smoking cessation counseling that focuses on the perceived risks of quitting smoking (e.g., weight gain, managing cravings and negative affect, loss of enjoyment).
- Trial name
- NCT01422239
- Testing
- Tailored treatment, Standard Treatment
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Yale University
Smoking, Pulmonary Disease, Chronic Obstructive
Smoking Cessation Versus Long-term Nicotine Replacement Among High-risk Smokers
Long-term NRT has not been studied in patients with COPD, and smokers in the United States with COPD are still asked to choose between immediate quitting or continued smoking.
- Conditions
- Smoking, Pulmonary Disease, Chronic Obstructive, Tobacco Use Disorder
- Trial name
- NCT02148445
- Testing
- Standard Smoking Cessation, Extended Nicotine Replacement Therapy, Nicotine replacement therapy
- Where
- United States
- Volunteers
- 398 people
- Sponsor
- University of Kansas Medical Center
Smoking Cessation, Smoking
A Randomized Controlled Trial of a Nurse Delivered Stage-matched Smoking Cessation Intervention to Promote Heart Health of Cardiac Patients
This study is a randomized controlled trial designed to evaluate the effectiveness of a nurse delivered stage-matched intervention to cardiac patients for cessation of tobacco use.
- Trial name
- NCT00563199
- Testing
- nurse-delivered stage-matched smoking cessation counseling
- Where
- 10 sites in China
- Volunteers
- 1,824 people
- Sponsor
- Hospital Authority, Hong Kong
Medication Adherence, Smoking Cessation
Helping People Adhere to Their Varenicline Treatment by Co-creating a Conversational Agent: A Feasibility Study
The goal of this feasibility study is to co-create and evaluate a theory informed, evidence-based, patient-centered healthbot aimed at helping people adhere to their varenicline regimen.
- Trial name
- NCT05997901
- Testing
- Varenicline healthbot
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Chronic Obstructive Pulmonary Disease (COPD), Asthma
Combined Bio- and Neuro- Feedback vs. Varenicline Use for Smoking Cessation
This study will develop and experimentally test the efficiency of a neurofeedback training protocol vs. varenicline use for smoking cessation.
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Asthma, Smoking
- Trial name
- NCT02991781
- Testing
- Biofeedback and Neurofeedback Training, Varenicline use for smoking cessation, Passive Control
- Where
- 3 sites in Bulgaria, Cyprus and 1 more
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Nicotine Dependence
Combination Nicotine Patch / Lorcaserin for Smoking Cessation
This study plans to compare the efficacy of the nicotine patch / lorcaserin combination treatment vs. the nicotine patch alone in terms of leading to a reduction in smoking behavior and withdrawal symptoms.
- Trial name
- LorNic (NCT02906644)
- Testing
- lorcaserin, nicotine patch
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Duke University
HRT, Non-HRT
Tobacco Cessation in Postmenopausal Women
This study investigated whether being on transdermal hormone replacement therapy (HRT) influenced smoking cessation variables in postmenopausal women undergoing short-term abstinence from cigarettes.
- Conditions
- HRT, Non-HRT, Continued Smoking, Smoking Abstinence
- Trial name
- NCT01210586
- Testing
- Part 2
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smoking Cessation
Bio-behavioral Lung Cancer Prevention Program
The overall goal of this research is to increase our understanding of the role of individual genetic differences in response to bupropion treatment and the psychobiological mechanisms by which genetic and treatment factors…
- Trial name
- NCT00322205
- Testing
- zyban
- Where
- United States
- Volunteers
- 555 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health (NIH)
Smoking Cessation
Creation of an Infrastructure to Support Delivery of mHealth Interventions for Cancer Patients
Despite the deleterious impact of smoking upon cancer treatment outcomes, smoking prevalence remains alarmingly high among cancer patients.
- Trial name
- Project mFLi (NCT06909357)
- Testing
- Quitline Treatment (QT), App-based Treatment (mHealth)
- Where
- 3 sites in United States
- Volunteers
- 38 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Smoking Cessation
Alcohol Control in Smoking Cessation
This study aims to develop a theory-driven, brief alcohol intervention protocol for HCPs to deliver the intervention for co-users of tobacco and alcohol during smoking cessation treatment.
- Trial name
- NCT05430529
- Testing
- Standard Smoke Cessation Service, Short Advice for Control Group, Brief Alcohol Intervention for Intervention Group
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
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