Clinical trials: Smoking Reduction
Smoking Cessation, Smoking Abstinence
Breathe 2 Project 3: Comprehensive Chronic Care
This study will evaluate Comprehensive Chronic Care (CCC), a healthcare treatment approach designed to increase smoking treatment engagement and abstinence among primary care patients who smoke.
- Trial name
- NCT05382221
- Testing
- Comprehensive Chronic Care, Standard Care
- Where
- 2 sites in United States
- Volunteers
- 979 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Smoking Cessation
Smoking Reduction or Cessation With Nicotine Replacement Therapy
The purpose of this study is to test the success rate of smoking reduction or cessation with different nicotine products.
- Trial name
- NCT00840242
- Testing
- Nicotine gum, Nicotine inhaler
- Where
- 2 sites in Czechia
- Volunteers
- 314 people
- Sponsor
- McNeil AB
Smoking
Pilot Study: Preoperative Nicotine Lozenges
The goal of this pilot study is to determine the feasibility and potential effect size of nicotine lozenges as an adjunct to maintain brief preoperative abstinence, defined as not smoking the day of surgery.
- Trial name
- NCT00586482
- Testing
- Nicotine Lozenge, Abstinence Advisement
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Mayo Clinic
Smoking Cessation, Lifestyle Risk Reduction
Empower Korean Families to End Tobacco Use & Smoking Exposure
The goals of the study are to develop a culturally and linguistically appropriate intervention to promote smoking cessation and reduce secondhand smoke exposure for Korean Americans using a family-based intervention approach…
- Trial name
- NCT04079569
- Testing
- Tobacco, Healthy Living
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Smoking Cessation, Smoking
The SmokeFree App Smoking Cessation Study
SmokeFree is a theory-driven and evidence-based stop smoking mobile application. Based on NICE guidance and best practice for smoking cessation, the application employs over 30 behaviour change techniques used in NHS Stop Smoking…
- Conditions
- Smoking Cessation, Smoking, Smoking Reduction, Smoking Habit
- Trial name
- SMOKEFREE (NCT05094583)
- Testing
- Use of SmokeFree app
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Nicotine Dependence
Smart Olfaction App to Reduce Relapse
The proposed project aims to refine and test a novel biobehavioral smoking cessation intervention that integrates the strategic application of olfactory stimulation to reduce cigarette craving with an established smartphone-based…
- Trial name
- SOARR (NCT07007195)
- Testing
- Ad Libitum Use followed by Instructed Use of the Inspire Device, Instructed Use followed by Ad Libitum Use of the Inspire Device, Smart-T Smoking Cessation App with the Inspire Device Condition
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Houston
Hypertension, Hyperlipidemia
Cardiovascular Lifestyle Study: Effects and Expense of a Cardiovascular Risk Reduction Clinic in Primary Care
The purpose of this trial is to study the effects on risk reduction and expense of 3 approaches to the care of people with cardiovascular risk factors in a naturalistic primary care environment.
- Conditions
- Hypertension, Hyperlipidemia, Hyperglycemia, Cardiovascular Disease
- Trial name
- NCT00291824
- Testing
- Cardiovascular risk factors and willingness to change
- Where
- Canada
- Volunteers
- 670 people
- Sponsor
- Caroline Medical Group
Smoking Cessation
Combining Varenicline and Bupropion for Smoking Cessation
The goal of this clinical research study is learn if the combination of Chantix (varenicline) and Zyban (bupropion) is more effective at helping people to quit smoking than varenicline when given alone.
- Trial name
- NCT00943618
- Testing
- Varenicline, Bupropion, Counseling/Phone Calls
- Where
- United States
- Volunteers
- 641 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Nicotine Dependence
Brain/Craving Response to Smoking Cues After Oral Nicotine Pouch Use
Oral nicotine pouches (ONPs) are non-combustible nicotine products that may reduce cigarette craving and smoking cue-induced brain activity, supporting their potential as harm-reduction tools for adults who smoke cigarettes.
- Trial name
- NCT07698470
- Testing
- Oral Nicotine Pouch, Smoking Cue Reactivity Task
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Alcohol Use, Smoking
Choices-Teen: A Bundled Risk Reduction Intervention for Juvenile Justice Females
This pilot study will: 1) demonstrate the feasibility of delivering CHOICES-TEEN with master's level mental health professionals within a juvenile justice setting; 2) determine acceptance of CHOICES-TEEN as measured by client…
- Conditions
- Alcohol Use, Smoking, Contraception, HIV
- Trial name
- NCT02252471
- Testing
- Choices-Teen
- Volunteers
- 28 people
- Sponsor
- University of Houston
Tobacco Use Disorder
Low Nicotine Content Cigarettes in Vulnerable Populations: Women of Reproductive Age
Despite marked reductions in cigarette smoking in the general population, smoking among economically disadvantaged women has increased.
- Trial name
- NCT04092387
- Testing
- Varying the nicotine content of cigarettes, E-Cigarettes
- Where
- 2 sites in United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Tobacco-Related Carcinoma
Episodic Future Thinking and Future Thinking Priming for Smoking Cessation
This trial studies the main and interactive effects of episodic future thinking and future thinking priming tasks on helping participants to quit smoking.
- Trial name
- NCT04297332
- Testing
- Behavioral Intervention, Informational Intervention, Nicotine Replacement
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Smoking Cessation, Harm Reduction
Assisting Smokers to Switch to an e-Cigarette by Accelerating Learning of Adaptive Habits Using D-cycloserine
This study will evaluate the effects of a reward devaluation strategy, which has been researched in the past, combined/augmented with the medication d-cycloserine in assisting smokers to switch from combustible cigarette (CC) to…
- Trial name
- NCT05994703
- Testing
- d-cycloserine, Juul e-cigarette
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Rose Research Center, LLC
Schizophrenia, Heavy Smoking
The Effect of Cigarette Holders, Plastic Menthol Cigarettes, and Cognitive Behavioral Therapy for Smoking Reduction Among Schizophrenia Inpatients: A Comparative Study
This study aims: 1. to assess the effect of smoking reduction programs (behavior therapy alone or behavior therapy with cigarette holders; "Flowers Menthol" plastic cigarettes with menthol) on cigarette smoking habits in an…
- Trial name
- NCT00302432
- Testing
- Behavior therapy, cigarette holders, Flowers Menthol
- Where
- Israel
- Volunteers
- 37 people
- Sponsor
- Lev-Hasharon Mental Healtlh Center
Copd, COPD Exacerbation
Atorvastatin Effect on Reduction of COPD Exacerbations
It is a randomized, multicenter, prospective, double-blind, placebo controlled, interventional clinical trial that will be conducted in Poland, in about 12 Hospital Pulmonary Departments to evaluate the effectiveness of…
- Conditions
- Copd, COPD Exacerbation, Smoking, Gene Expression
- Trial name
- Captain (NCT04789057)
- Testing
- Atorvastatin 40 Mg Oral Tablet
- Where
- Poland
- Volunteers
- 460 people
- Sponsor
- Medical University of Bialystok
Hiv, Tobacco Use
Trial of a Harm Reduction Strategy for People With HIV Who Smoke Cigarettes
Cigarette smoking is now the leading killer of people with HIV (PWH) in the US, and most cessation strategies tried to date have failed to increase long-term quit rates.
- Trial name
- NCT05642715
- Testing
- EX+, Varenicline, HR
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Smoking, Pain
Online Automated Self-Hypnosis Program
After developing professional quality materials (audio) for an affordable automated self-hypnosis intervention program for facilitating smoking cessation, stress and pain reduction, researchers aim to gain qualitative reviews of…
- Conditions
- Smoking, Pain, Stress
- Trial name
- NCT03931772
- Testing
- Automated Self-Hypnosis
- Where
- 2 sites in United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Stanford University
Alcoholism, Substance-Related Disorders
Study of Effectiveness of Adding the Health Promotion and Rehabilitation for Treatment for Alcohol and Drug Abusers
The purpose of this study is to evaluate the effect of adding the Health Promotion activities and rehabilitation to the usual alcohol and drug interventions on the outcome for alcohol and drug abusers compared to the usual…
- Conditions
- Alcoholism, Substance-Related Disorders, Smoking, Chronic Disease
- Trial name
- VIP (NCT01414907)
- Testing
- Health promotion activities
- Where
- Sweden
- Volunteers
- 214 people
- Sponsor
- Skane University Hospital
Nicotine Dependence
Study Two on the Effectiveness of Mindfulness Training for Smokers
The MTS2 study enrollment goal is N=240 adult smokers randomized to study treatments. The study design includes two randomized arms to compare matched intensive interventions and a third non-randomized option for participants who…
- Trial name
- MTS2 (NCT01299909)
- Testing
- Integrated Training for Smokers, Mindfulness Training for Smokers, Quitline
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- University of Wisconsin, Madison
Tobacco Dependence
Effect of Yoga on Reducing Craving in Tobacco Dependent Individuals
Yoga is a culturally acceptable practice that can reduce craving and help people quit tobacco. There is a need to evaluate the feasibility of implementation of a well- designed yoga protocol to address craving in individuals who…
- Trial name
- NCT06488443
- Testing
- Yoga, WHO 5As model intervention
- Where
- India
- Volunteers
- 96 people
- Sponsor
- University of Pittsburgh