Clinical trials: Smoking-related Pathology
Tobacco Use Disorder
Modification of Goal-directed and Habitual Behavior in Addiction
This study aims to examine the modification of the hypothesized imbalance between goal-directed and habitual behavior and its neural correlates in smokers.
- Trial name
- NCT03764969
- Testing
- standard smoking cessation program (SCP), Cognitive remediation treatment (CRT), Implicit computer-based habit-modifying training (ICHT)
- Where
- Germany
- Volunteers
- 75 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Nicotine Dependence
Targeted Interventions for Weight-Concerned Smokers
Weight gain after quitting smoking is an important barrier to treatment for many smokers. This study will test a drug called naltrexone with weight-concerned smokers to investigate whether or not this drug both improves smoking…
- Trial name
- NCT00105482
- Testing
- Naltrexone, Transdermal nicotine replacement, Behavioral counseling
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- Yale University
Tobacco Use Disorder, Oral Nicotine Pouch Use
Switching to Potential Reduced Exposure Products in Adult Smokers
This study aims to assess the feasibility, acceptability, and the potential harm reduction of switching to potentially lower risk, oral nicotine pouches in adult smokers.
- Conditions
- Tobacco Use Disorder, Oral Nicotine Pouch Use, Smoking Behaviors, Harm Reduction
- Trial name
- ZYN (NCT04250727)
- Testing
- ZYN
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Yale University
Tobacco Use Disorder
Effects of Mindfulness Meditation in Virtual Reality on Craving and Smoking Cessation
Investigators seek to propose a non-drug therapeutic alternative, namely a mindfulness meditation protocol based on virtual reality training in order to induce progressive modifications of various indicators of craving.
- Trial name
- VIREAMIND (NCT05766553)
- Testing
- Virtual reality pod, nicotine patches and chewing gum
- Where
- 3 sites in France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Henri Laborit
Electronic Cigarette Related Lung Damage
Dissolved Phase HXe-129 MRI: A Novel Biomarker to Quantify Pulmonary Pathology
A two-center, longitudinal assessment of 40 electronic cigarette users and 40 healthy controls at the initial visit and a follow-up visit 12 months later.
- Trial name
- ECig (NCT06856525)
- Testing
- Hyperpolarized xenon 129, Cardiopulmonary Stress Test, Pulmonary Function Test
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Y. Michael Shim, MD
Cardiovascular Diseases, Chronic Obstructive Pulmonary Diseases
The Efficacy and Safety of Electronic Cigarettes: a 5-year Follow-up Study
The main aim of this multicentric 5-year follow-up study is to evaluate for the first time the long-term efficacy and safety (in terms of smoking-related serious diseases requiring hospitalization) of e-cigarette smoking…
- Conditions
- Cardiovascular Diseases, Chronic Obstructive Pulmonary Diseases, Cancer of the Lung, Cancer of the Bladder
- Trial name
- NCT01785537
- Where
- Italy
- Volunteers
- 1,050 people, healthy volunteers welcome
- Sponsor
- Università degli Studi 'G. d'Annunzio' Chieti e Pescara
Asthma in Children, Wheezing
Secondhand Smoking in Asthmatic Children
This study will investigate the interaction between GSTP1 / TNFa polymorphisms and passive smoking in children with asthma/wheezing. Contemporary second hand-smoke exposure will be confirmed by laboratory testing.
- Trial name
- NCT03099902
- Testing
- Lung function, White blood cell DNA extraction, Urinary testing
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- AHEPA University Hospital
Smoking, Pain
Pain and Smoking Study
This purpose of this study is to test the telephone delivery of a cognitive behavioral intervention (CBI), for smoking cessation among Veteran smokers with chronic pain
- Conditions
- Smoking, Pain, Smoking Cessation
- Trial name
- PASS (NCT02971137)
- Testing
- Smoking Cessation plus CBI, Smoking Cessation Standard
- Where
- 2 sites in United States
- Volunteers
- 371 people
- Sponsor
- VA Office of Research and Development
Tobacco Use Disorder, Nicotine Addiction
Cognitive Training for Nicotine Dependence
This randomized clinical trial tested the effects of a computerized (web-based) cognitive training intervention on smoking cessation.
- Trial name
- NCT01252966
- Testing
- Cognitive Training, Control training
- Where
- United States
- Volunteers
- 213 people
- Sponsor
- University of Pennsylvania
Pulmonary Disease, Chronic Obstructive
Effect of Spiriva® on Health-related Quality of Life in Chronic Obstructive Pulmonary Disease (COPD) Patients Who Stopped Smoking During Treatment.
Post marketing Surveillance to gain insights into the effects of therapy with Spiriva® (tiotropium bromide) on health-related quality of life in COPD patients who stopped smoking during treatment and to obtain safety data…
- Trial name
- NCT02172547
- Testing
- Spiriva
- Volunteers
- 10,821 people
- Sponsor
- Boehringer Ingelheim
Smoking Cessation
Not Quite Ready to Quit
In our communications with the public, the investigators will call this the Not Quite Ready to Quit Smoking Study. One new method to increase quit attempts is to have smokers reduce their cigs/day.
- Trial name
- NCT01866722
- Testing
- Usual care, Reduction, 5Rs
- Where
- United States
- Volunteers
- 560 people
- Sponsor
- University of Vermont