Clinical trials: Snoring
Obstructive Sleep Apnea, OSA
Treating Obstructive Sleep Apnea Using Targeted Hypoglossal Neurostimulation
Multi-center, open-label, prospective, randomized clinical trial of the aura6000(R) System for the reduction of apnea and hypopneas in adult patients with moderate to severe obstructive sleep apnea who have failed or are…
- Conditions
- Obstructive Sleep Apnea, OSA, Apnea, Apnea, Obstructive
- Trial name
- OSPREY (NCT04950894)
- Testing
- Hypoglossal Nerve Stimulation
- Where
- 19 sites in United States
- Volunteers
- 107 people
- Sponsor
- LivaNova
Snoring, Obstructive Sleep Apnea
Efficacy, Safety and Acceptability of Nastent™ in Snoring and Obstructive Sleep Apnea
This study evaluates the efficacy, the tolerance and the acceptability/compliance of the nasal airway stent, Nastent, for the treatment of mild to moderate OSA and snoring in European adult patients without cardiovascular and/or…
- Trial name
- NCT03510403
- Testing
- nastent™
- Where
- 6 sites in France
- Volunteers
- 32 people
- Sponsor
- Seven Dreamers Europe SAS
Sleep Disordered Breathing
Effects of Earplugs on Sleep and Sleep Apnea
The main goal of this study is to assess whether use of earplugs has any effect on sleep, sleep apnea, and daytime sleepiness in individuals who snore.
- Trial name
- NCT01062854
- Testing
- Soft earplugs are worn during sleep study
- Where
- United States
- Volunteers
- 407 people
- Sponsor
- University of Michigan
Snoring
Neostigmine For Snoring During DISE
The study team is seeking a novel treatment for snoring involving local application of a nerve stimulant medication, neostigmine.
- Trial name
- NCT03316963
- Testing
- Neostigmine Methylsulfate
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Emory University
Snoring
Study of Nasal Airflow Pressure Optimization to Resolve Excessive Snoring
This is a prospective, interventional, study in which patients with a history of habitual snoring to determine whether low pressure nasal continuous airway pressure can reduce the frequency, duration or intensity of snoring in…
- Trial name
- SNORE (NCT01949584)
- Testing
- nasal continuous positive airway pressure less than or equal to 6 cm H2O
- Where
- 3 sites in United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- inSleep Technologies, LLC
Obstructive Sleep Apnea, Snoring
A Trial to Evaluate a Device for the Treatment of OSA and Snoring
To evaluate the safety and efficacy of the Tongue Advancement Retainer Device in treating subjects with Obstructive Sleep Apnea (OSA) and snoring.
- Trial name
- OPEN (NCT01772017)
- Testing
- Tongue Advancement Retainer Device
- Where
- 3 sites in United States, Australia
- Volunteers
- 15 people
- Sponsor
- Sleepy, Inc
Snoring
Upper Airway Obstruction in Non-obese Patients With Snoring and Obstructive Sleep Apnea
This study aims at :- 1. detecting the prevelance of snoring and OSA in non-obese patients 2. identify their diagnostic profile in order to provide proper management
- Trial name
- NCT04324671
- Testing
- nasofibroscopy
- Volunteers
- 40 people
- Sponsor
- Assiut University
Snoring
Pilot Study of cNEP for the Treatment of Snoring
This pilot study will examine the efficacy and safety of continuous negative external pressure ("cNEP") for the treatment of chronic snoring in people without obstructive sleep apnea.
- Trial name
- NCT02767843
- Testing
- continuous negative external pressure (cNEP)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Sommetrics, Inc.
Respiratory Disease
Luftibus in the School: a Study on the Respiratory Health of Schoolchildren.
This study assessed the respiratory health of schoolchildren from the canton of Zurich by combining self-reported information on respiratory symptoms with lung function test results and air pollution measurements.
- Trial name
- LUIS (NCT03659838)
- Where
- Switzerland
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Snoring, Sleep Apnea
Multidimensional System as Predictor of Outcomes in Obstructive Sleep Apnea: The OSA-SCORE
Purpose: In a retrospective cohort the investigators will validate, the goodness of a multidimensional index to classified the severity of patients with sleep disordered breathing that has been previously developed in a…
- Trial name
- OSA-SCORE (NCT01175421)
- Where
- Spain
- Volunteers
- 1,100 people
- Sponsor
- Hospital Miguel Servet
Sleep Apnea, Snoring
Substantial Equivalence of iSlpr™ and SomnoDent® Classic in the Treatment of Snoring and Mild to Moderate Sleep Apnoea.
The study is a thirty three week, prospective, open-label, randomized, parallel-group non-inferiority study. The study aims to investigate the Substantial Equivalence of a novel mandibular device called iSlpr™, produced by…
- Trial name
- NCT04250584
- Testing
- iSlpr™, SomnoDent® Classic
- Volunteers
- 66 people
- Sponsor
- BioAnalytics Holdings Pty Ltd
Snoring, Mouth Breathing
OA Therapy for Mouth-breathers Who Snore
Breathing is one of the body's vital functions that occur under normal conditions using the nose. When humans breathe primarily through the mouth instead of the nose, this is referred to as mouth breathing.
- Conditions
- Snoring, Mouth Breathing, Obstructive Sleep Apnea
- Trial name
- OATMB (NCT04876625)
- Testing
- myTAP oral appliance plus mouth shield, myTAP oral appliance alone for first 4 weeks
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Snoring
Mandibular Advancement vs Home Treatment for Primary Snoring
This is a randomized controlled trial for non-apneic snorers. The primary goal of the study is to evaluate the efficacy of a mandibular advancement device (MAD) vs conservative treatment for adults with non-apneic snoring as…
- Trial name
- NCT05756647
- Testing
- Interventional Arm, Conservative treatment Arm
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Washington University School of Medicine
Obstructive Sleep Apnea Syndrome
High and Low Intensity Expiratory Muscle Strength Training in Patients With Obstructive Sleep Apnea Syndrome
The effect of expiratory muscle strength training (EMST) on sleep quality, disease severity, and respiratory muscle strength has been previously investigated in OSA syndrom.
- Trial name
- NCT04454242
- Testing
- Expiratory muscle trainig
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Ahi Evren Chest and Cardiovascular Surgery Education and Research Hospital
Atrial Fibrillation (AF), OSA - Obstructive Sleep Apnea
Impact of Atrial Fibrillation Ablation on Sleep Parameters.
Assessment of Sleep Parameters Using Polygraphy in Patients with Paroxysmal Atrial Fibrillation Qualified for Pulmonary Vein Isolation - A Prospective Observational Study: Afib Ablation and Hypopnea Index - The "AAHI" Study…
- Conditions
- Atrial Fibrillation (AF), OSA - Obstructive Sleep Apnea, Pulmonary Vein Isolation
- Trial name
- AAHI (NCT07259200)
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Primula Clinics
Sleep-disordered Breathing, Snoring
Hemodynamics Response to Upper Airway Obstruction in Marfan Syndrome
Upper airway obstruction (UAO) is an unrecognized source of hemodynamic stress that may contribute to aortic adverse events in persons with Marfan Syndrome (MFS).
- Trial name
- MSB (NCT03985657)
- Testing
- CPAP
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Sleepiness, SARS-CoV2 Infection
Obstructive Sleep Apnoea Post Covid 19: Role of the Upper Airway Microbiome
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) causing coronavirus disease, Covid-19, has spread rapidly across the globe since its emergence in January 2020.
- Conditions
- Sleepiness, SARS-CoV2 Infection, Fatigue Syndrome, Chronic, Snoring
- Trial name
- NCT05116657
- Testing
- Nasal Lavage and Oral Wash
- Volunteers
- 50 people
- Sponsor
- Royal College of Surgeons, Ireland
Obstructive Sleep Apnea
Therapeutic Efficiency of Mandibular Advancement Device Using Smartphone Sleep Applications and Pulse Oximeter
An observational clinical trial in a single centre. The objective of this study was to determine the efficacy of mandibular advancement device (MAD) therapy on snoring intensity, frequency, and oxygen desaturation periods in…
- Trial name
- NCT04427111
- Testing
- Non-titratable-customized mandibular advancement device
- Volunteers
- 18 people
- Sponsor
- Bahadır EZMEK
Obstructive Sleep Apnea Syndrome
Follow-up Studies of Primary Snoring(PS) and Obstructive Sleep Apnea Hypopnea Syndrome(OSAHS) in Chinese Children
The study is designed to investigate the natural course of Primary snoring in 1-2 years or more and the different effect of drug and surgical treatment applied in children with obstructive sleep apnea (OSAS) by comparing the…
- Trial name
- NCT02447614
- Testing
- Adenotonsillectomy, Conservative treatment, no treatment
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Beijing Children's Hospital
Airway Obstruction, Snoring
Anti-Snoring Appliances and Airway Manipulation in Patients Undergoing Anesthetic Sedation
Would patients using an anti-snoring appliance intraoperatively require less airway manipulation, interventions, and rescue maneuvers during anesthetic sedation cases compared to those who do not? The investigators will use…
- Conditions
- Airway Obstruction, Snoring, Sedation Complication
- Trial name
- NCT05748626
- Testing
- Anti-snoring device, No anti -snoring device during their procedure.
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Northwestern University