Clinical trials: Social Anxiety Disorder
Social Anxiety Disorder (SAD)
A Study of NTX-1472 in Social Anxiety Disorder
The primary goal of this Phase 2 clinical trial is to determine the effects of a novel V1a receptor antagonist (NTX-1472) in adults with Social Anxiety Disorder (SAD).
- Trial name
- SOAR (NCT07323784)
- Testing
- NTX-1472
- Where
- 11 sites in United States
- Volunteers
- 100 people
- Sponsor
- Newleos Therapeutics, Inc.
Social Anxiety Disorder (SAD)
A Study of ONO-1110 in Patients With Social Anxiety Disorder
To Evaluate the Efficacy and Safety of ONO-1110 in Patients with Social Anxiety Disorder
- Trial name
- NCT06805565
- Testing
- ONO-1110
- Where
- 27 sites in Japan
- Volunteers
- 115 people
- Sponsor
- Ono Pharmaceutical Co., Ltd.
Anxiety, Stress
WRITE: Written Imaginal Thinking Exercise Study
The purpose of the study is to investigate and compare the effects of three different versions of a future imaginal writing exercise (worst-case scenario, neutral future scenario, best-case scenario) for individuals with elevated…
- Conditions
- Anxiety, Stress, Social Anxiety
- Trial name
- WRITE (NCT07464158)
- Testing
- Worst-Case Scenario Written Exposure Exercise, Neutral Future Scenario Written Exercise, Best-Case Scenario Written Exposure Exercise
- Where
- United States
- Volunteers
- 353 people
- Sponsor
- University of Colorado, Boulder
Anxiety, Separation, Anxiety, Generalized
Partners in Caring for Anxious Youth
Pediatric onset anxiety disorders (generalized anxiety, social anxiety, separation anxiety) are highly prevalent, and if untreated, are impairing into adolescence and adulthood.
- Conditions
- Anxiety, Separation, Anxiety, Generalized, Anxiety, Social
- Trial name
- PCAY (NCT04598230)
- Testing
- Cognitive Behavioral Therapy (CBT), Combination therapy (COMB)
- Where
- 3 sites in United States
- Volunteers
- 468 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Social Anxiety Disorder
Waitlist-Control Trial of Smartphone (App-based) CBT for Social Anxiety Disorder (SAD), Withdrawn
The investigators are testing the efficacy of Smartphone-delivered cognitive behavioral therapy (CBT) treatment for social anxiety disorder (SAD).
- Trial name
- NCT04622930
- Testing
- Smartphone-delivered CBT for SAD
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Anxiety Disorders, Generalized Anxiety Disorder
Computerized Intervention Targeting the Error-Related Negativity and Balance N1 in Anxious Children
Anxiety disorders are the most common form of psychopathology, and frequently begin in childhood, resulting in lifelong impairment.
- Conditions
- Anxiety Disorders, Generalized Anxiety Disorder, Social Anxiety Disorder, Obsessive-Compulsive Disorder
- Trial name
- NCT05503017
- Testing
- Psycho-social, computerized intervention targeting error sensitivity, Psycho-social, computerized intervention on healthy lifestyle choices
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- Florida State University
HIV - Human Immunodeficiency Virus, Mental Health
Integrating Project YES! With WHO-Endorsed Mental Health Approaches Among Youth Living With HIV
The proposed study will address the intersecting stigmas of HIV, violence and depression among adolescents and young adults (15-24) living with HIV (AYALHIV) in Zambia.
- Conditions
- HIV - Human Immunodeficiency Virus, Mental Health, Anxiety, Depression in Adolescence
- Trial name
- NCT07221201
- Testing
- Project YES+ intervention arm
- Where
- Zambia
- Volunteers
- 323 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Social Anxiety Disorder (SAD), Attention Bias Modification Treatment (ABMT)
Efficacy of Attention Bias Modification vs. Placebo for Social Anxiety Disorder
This study examines whether a computerized attention-training intervention called attention bias modification (ABM) can reduce symptoms of social anxiety disorder (SAD) in adults, and whether symptom improvement is specifically…
- Conditions
- Social Anxiety Disorder (SAD), Attention Bias Modification Treatment (ABMT), Placebo Effect
- Trial name
- NCT07666776
- Testing
- Dot-Probe Attention Bias Modification (ABM)
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- Tel Aviv University
Major Depressive Disorder, Social Anxiety Disorder
Transdiagnostic Brain-Behavior Profiling to Enhance Cognitive Behavioral Therapy Response
Many patients with Major Depressive Disorder (MDD) and generalized Social Anxiety Disorder (gSAD) are treated with cognitive behavioral therapy (CBT) but few have meaningful improvement.
- Trial name
- NCT03175068
- Testing
- CBT, ST
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago
Social Anxiety Disorder
Dose Timing of D-Cycloserine to Augment CBT for Social Anxiety Disorder
The purpose of this study is to examine the efficacy of 50 mg of d-cycloserine in comparison to placebo (a pill containing no medication) for improving the effectiveness of cognitive-behavioral therapy (CBT) in reducing symptoms…
- Trial name
- NCT02066792
- Testing
- D-Cycloserine, Cognitive Behavioral Therapy
- Where
- 3 sites in United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Jasper A. Smits
Social Anxiety Disorder
Hormones and Social Anxiety Disorder Treatment
The purpose of this study is to determine whether power posing (i.e., holding poses associated with dominance and power), compared to submissive posing or rest, prior to exposure therapy for social anxiety disorder: 1) leads to a…
- Trial name
- NCT02482805
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Jasper A. Smits
Obsessive-Compulsive Disorder, Post Traumatic Stress Disorder
CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based Therapy
Anxiety-, obsessive-compulsive and trauma- and stressor-related disorders reflect a significant public health problem. This study is designed to evaluate the predictive power of a novel biomarker based on a CO2 challenge, thus…
- Conditions
- Obsessive-Compulsive Disorder, Post Traumatic Stress Disorder, Generalized Anxiety Disorder, Social Anxiety Disorder
- Trial name
- NCT05467683
- Testing
- Exposure-Based Therapy
- Where
- 2 sites in United States
- Volunteers
- 600 people
- Sponsor
- Jasper A. Smits
Sexual and Gender Minorities, Social Stigma
Examining the Health Effects of NPOWER365 Among Black Same Gender Loving Men
This research study aims to test the effectiveness, reach, and maintenance over time of the NPOWER365 HIV care intervention for Black men who have sex with men (BMSM) living with HIV.
- Conditions
- Sexual and Gender Minorities, Social Stigma, Medication Adherence, Depressive Symptoms
- Trial name
- NCT06315218
- Testing
- NPOWER365 HIV care intervention
- Volunteers
- 350 people
- Sponsor
- Rutgers, The State University of New Jersey
Anxiety, Social Anxiety Disorder
Neurofeedback Enhanced Cognitive Reappraisal Training - Phase 4
This study seeks to understand emotion regulation in those with young adults with anxiety using real-time functional magnetic resonance imaging neurofeedback, a tool that allows individuals to control brain activity.
- Conditions
- Anxiety, Social Anxiety Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- NCT06563310
- Testing
- Functional magnetic resonance imaging (fMRI) with Veritable-NF
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Michigan
Anxiety Disorders, Obsessive-Compulsive Disorder
Brief-intensive CBT Versus Once-weekly CBT in Anxiety-related Disorders
The goal of this clinical trial is to compare brief-intensive cognitive-behaviour therapy (CBT) with regular weekly CBT in people with anxiety-related disorders.
- Conditions
- Anxiety Disorders, Obsessive-Compulsive Disorder, Posttraumatic Stress Disorder, Hypochondriasis
- Trial name
- KOMMA (NCT05942391)
- Testing
- Cognitive behavioral therapy (CBT)
- Where
- 6 sites in Netherlands
- Volunteers
- 120 people
- Sponsor
- Amsterdam UMC, location VUmc
Social Anxiety Disorder (SAD)
Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults With Social Anxiety Disorder (PALISADE-4)
This U.S. Phase 3 clinical trial is designed to evaluate the efficacy, safety, and tolerability of the acute intranasal (i.n.) administration of Fasedienol Nasal Spray (fasedienol) (3.2 µg) to relieve symptoms of acute anxiety in…
- Trial name
- PALISADE-4 (NCT06615557)
- Testing
- Fasedienol Nasal Spray
- Where
- 26 sites in United States
- Volunteers
- 238 people
- Sponsor
- VistaGen Therapeutics, Inc.
Social Anxiety Disorder
Efficacy of BNC210 in Acute, As-needed Treatment of Anxiety in Social Anxiety Disorder - 1
The purpose of the study is to evaluate the effect of a single, acute dose of BNC210 compared to placebo on reducing the severity of anxiety provoked by a behavioral assessment task and measured using the Subjective Units of…
- Trial name
- AFFIRM-1 (NCT06510504)
- Testing
- 225 mg BNC210
- Where
- 21 sites in United States
- Volunteers
- 370 people
- Sponsor
- Bionomics Limited
Depression in Adolescence, Anxiety
Application for Arts-Based Social Prescribing
The goal of this clinical trial is to learn if a personalized arts-based social prescribing program, Art Pharmacy, delivered through a mobile app (SocialRx App) can improve mental health and social connectedness in adolescents…
- Conditions
- Depression in Adolescence, Anxiety, Loneliness, Social Connectedness
- Trial name
- NCT07593443
- Testing
- Art Pharmacy, Stable treatment
- Volunteers
- 230 people
- Sponsor
- SocialRx Inc
Autism Spectrum Disorder (ASD)
Acceptance and Commitment Therapy for Parents of Children With ASD: Effects on Cognitive Fusion, Stigma, and Mindfulness
The goal of this intervention is to evaluate whether Acceptance and Commitment Therapy (ACT) can improve psychological well-being among parents of children with Autism Spectrum Disorder (ASD) in Saudi Arabia.
- Trial name
- ACT-CFSM (NCT07582627)
- Testing
- Acceptance and Commitment Therapy (ACT)
- Where
- Saudi Arabia
- Volunteers
- 30 people
- Sponsor
- University of Jazan
Panic Disorder With Agoraphobia, Panic Disorder Without Agoraphobia
A Transdiagnostic, Self-guided Internet Intervention ("Velibra") for Waitlist Patients With Anxiety Disorders
The project's aim is to investigate the effect of a transdiagnostic, self-guided, internet-based cognitive behavioral therapy program in waitlist patients with anxiety disorders.
- Conditions
- Panic Disorder With Agoraphobia, Panic Disorder Without Agoraphobia, Generalized Anxiety Disorder, Social Anxiety Disorder
- Trial name
- NCT04793828
- Testing
- Velibra
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Charite University, Berlin, Germany