Clinical trials: Social Engagement
HIV
Using MOST to Optimize an HIV Care Continuum Intervention for Vulnerable Populations
The present study targets the large population of persons living with HIV/AIDS (PLHA) in the U.S. who are both insufficiently engaged in HIV primary care and not taking antiretroviral therapy (ART), who are mainly African…
- Trial name
- HTH2-MOST (NCT02801747)
- Testing
- Heart to Heart2 (HTH2)
- Where
- United States
- Volunteers
- 512 people
- Sponsor
- New York University
Tobacco Use Cessation
Engagement With an Adaptive Mobile Health Smoking Cessation Intervention
This is a pilot sequential multiple assignment trial (SMART) to understand the optimal timing to assess response to our smoking cessation text message intervention and to measure how adding medications alone compares to adding…
- Trial name
- NCT04020718
- Testing
- Brief telephone advice plus tailored text messages, Mailed nicotine replacement therapy, Proactive telephone coaching
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Massachusetts General Hospital
Healthy Volunteers, Cardiometabolic Diseases
A Study to See How Safe a New Medicine (NNC6022-0001) is in Healthy People
The study is testing a new study medicine, which is being tested as a potential medicine to treat cardiometabolic diseases. The aim of this study is to see if the study medicine is safe, how it works in participants body, and…
- Trial name
- NCT06336005
- Testing
- NNC6022-0001
- Where
- Netherlands
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
HIV, Patient Compliance
Intervention to Improve Engagement in Care Among Newly Diagnosed HIV-positive Men
The study involves delivering one of two interventions - either Promoting Action Towards Health (PATH) or Personalized Cognitive Counseling (PCC) - to 440 men who have sex with men (MSM) who have recently been diagnosed with HIV…
- Trial name
- NCT01559805
- Testing
- Positive Choices, Personalized Cognitive Counseling
- Where
- 4 sites in United States
- Volunteers
- 202 people
- Sponsor
- Columbia University
Parent-Child Relations, Parenting
Examine the Feasibility and Acceptability of Project Support
In this study, the investigators will conduct a proof-of-concept pilot trial of delivering the Project Support Positive Parenting Module (Project Support) to n = 30 families waiting for trauma-focused services.
- Conditions
- Parent-Child Relations, Parenting, Child Mental Disorder
- Trial name
- NCT06391229
- Testing
- Project Support
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Medical University of South Carolina
Joint Engagement + Enhanced Milieu Training, Joint Engagement + Enhanced Milieu Training+Augmentative Communication (AAC)
Developmental and Augmented Intervention for Facilitating Expressive Language
This study will contrast two experimental treatment conditions by testing whether joint attention/joint engagement intervention using spoken communication (JAE-EMT) results in better outcomes than joint attention/joint engagement…
- Trial name
- CCNIA (NCT01013545)
- Testing
- JAE Intervention
- Where
- 3 sites in United States
- Volunteers
- 96 people
- Sponsor
- Autism Speaks
Healthy Volunteers, Ulcerative Colitis
Single Ascending Dose and Multiple Ascending Dose Study in Healthy Participants and Proof of Mechanism Study in Patients With Ulcerative Colitis
The primary purpose of this study is to determine if single and multiple doses of BMS-986184 are safe and well tolerated in healthy male and female subjects.
- Trial name
- NCT02864264
- Testing
- BMS-986184
- Where
- 3 sites in Australia, Georgia and 1 more
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Conduct Problems
Parent Preferences and Family Engagement in a Conduct Problems Prevention Program
The purpose of this study is to gain a better understanding of family preferences for and engagement in services.
- Trial name
- NCT02432014
- Testing
- PMTO-PTC Group clinic-based, PMTO Individual home-based, PMTO Individual clinic-based
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- University of Minnesota
Chronic Low Back Pain (CLBP)
Empowering Pain Psychology Access and Collaboration (EPPAC) to Improve Treatment Engagement Among Medicaid-insured Adults With Chronic Low Back Pain
Chronic low back pain (cLBP) is a leading cause of disability, with socioeconomically disadvantaged populations experiencing worse outcomes and lower rates of treatment initiation for evidence-based pain psychology services.
- Trial name
- NCT07843706
- Testing
- Empowering Pain Psychology Access and Collaboration (EPPAC), Usual Care Pain Psychology Evaluation
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Johns Hopkins University
Improving Perceptions of HIV Risk, Improving Uptake of Pre-exposure Prophylaxis for HIV
Manicaland PrEP Uptake Through Interactive Counselling Trial
Primary Objective: The purpose of this trial is to evaluate the impact of an interactive tablet based counselling session correcting risk perception and addressing ambiguity around availability, usability and effectiveness of…
- Trial name
- NCT03565575
- Testing
- Interactive tablet-based quiz
- Where
- 8 sites in Zimbabwe
- Volunteers
- 1,055 people, healthy volunteers welcome
- Sponsor
- Simon Gregson
Weight Management
CORE Study - Research Into Weight Management Services in the UK
Weight management services (previously known as Tier 3 services) represent a multidisciplinary specialist approach, available in community or secondary care settings.
- Trial name
- CORE (NCT07559409)
- Where
- United Kingdom
- Volunteers
- 41,000 people
- Sponsor
- Society for Endocrinology
Smoking Cessation
Promoting Smoking Cessation in the Community Via "Quit to Win" Contest 2026: Engagement-Focused GenAI-based Chatbot for Real-Time Smoking Cessation Support
The goal of this trial is to learn if chatbot-based instant messaging works to help smoking cessation in general adult smokers. It will also learn about the experience, attitude, and perception of using an LLM-based chatbot.
- Trial name
- QTW2026 (NCT07649044)
- Testing
- AWARD advice, Brief leaflet on health warning and smoking cessation, Referral card
- Where
- Hong Kong
- Volunteers
- 998 people
- Sponsor
- The University of Hong Kong
Patient Engagement, Femoral Angiography
Use of Back Support After Transfemoral Angiography
In the routine treatment procedure after coronary angiography (CAG), the patients remain in the supine position for a long time, which leads to decreased venous return and back pain.
- Trial name
- NCT06643182
- Testing
- Back Support
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Inonu University
Family Engagement, Virtual
Virtual Family Participation in ICU Rounds: A Pilot Study
Barriers to family participation in ICU rounds exist at the health care system level (e.g., restriction on visitation, infection control) and the individual level (e.g., caretaker role, illness, disability, inability to miss…
- Conditions
- Family Engagement, Virtual, Critical Care
- Trial name
- VR-Family (NCT05891860)
- Testing
- Participation in virtual rounds
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Lady Davis Institute
Major Depressive Disorder
Exploring Engagement With Remote Symptom Tracking for Depression (RADAR: Engage)
The aim of this study is to understand how best to promote engagement with remote measurement technology (RMT) research in major depressive disorder, using the RADAR-MDD infrastructure as a case study.
- Trial name
- NCT04972474
- Testing
- Smartphone app in-app components
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- King's College London
Cancer
Reducing Emotional Distress, Enhancing Function and Improving Network Engagement in Adolescent and Young Adult Oncology
We propose to examine the effects of mindfulness based stress reduction (MBSR) on outcomes of health related quality of life, disease symptoms, and biological correlates of stress in a sample of young adults with cancer.
- Trial name
- REDEFINEAYAO (NCT02495376)
- Testing
- MBSR
- Where
- 2 sites in United States
- Volunteers
- 151 people
- Sponsor
- Northwestern University
Engagement, Patient
QT-Digital Mental Health Engagement Study
Sexual and gender minority (SGM) populations are disproportionately impacted by mental health concerns relative to their heterosexual and cisgender peers.
- Trial name
- QT-DIMES (NCT07278765)
- Testing
- HAPA Engagement Strategies
- Where
- 2 sites in United States
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- University of Washington
HIV
Chemsex Health Evaluation With Extended Release System for HIV Treatment
CHEERS is an observational cohort for people living with HIV who are actively practicing chemsex and who are switching to CAB + RPV LA after being virologically suppressed on a stable oral ART regimen.
- Trial name
- CHEERS (NCT06565013)
- Testing
- Cabenuva 600/900, Self administered questionnaires, Semi-directed interview
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Clinique Médicale L'Actuel
HIV/AIDS
Minority AIDS Initiative Retention and Re-Engagement Project
The purpose of this study is to determine whether an enhanced peer intervention is effective in retaining and re-engaging at-risk people of color living with HIV/AIDS into care.
- Trial name
- NCT01616940
- Testing
- Enhanced Peer Intervention
- Where
- 4 sites in United States, Puerto Rico
- Volunteers
- 348 people
- Sponsor
- Boston University
Metabolic Syndrome (MetS)
Use of a Mobile Application for Tracking Physical Activity in the Management of Metabolic Syndrome in Primary Care
This study will explore whether integrating a mobile app to track physical activity-recommended by family doctors during routine primary care visits-can help individuals with metabolic syndrome become more active.
- Trial name
- IMAFIL (NCT07236450)
- Testing
- Mobile Application and Wearable Device for Physical Activity Monitoring
- Where
- Portugal
- Volunteers
- 100 people
- Sponsor
- Andreia Lobo
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