Clinical trials: Social Interaction
Breast Cancer
Docetaxel, Doxorubicin, and Cyclophosphamide in Treating Women With Advanced Breast Cancer
RATIONALE: Drugs used in chemotherapy, such as docetaxel, doxorubicin, and cyclophosphamide, use different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00074139
- Testing
- cyclophosphamide, docetaxel, doxorubicin hydrochloride
- Where
- United States
- Sponsor
- Case Comprehensive Cancer Center
Child Development Disorders, Pervasive, Problems Psychosocial
Effect of Problem-Solving Training
The aim of this study, therefore, is to determine the effect of problem-solving training on the interpersonal problem-solving skills of mothers with special needs children. This study was a parallel randomized controlled trial.
- Conditions
- Child Development Disorders, Pervasive, Problems Psychosocial, Mother-Infant Interaction
- Trial name
- AtaturkU (NCT05688319)
- Testing
- Problem-Solving Training
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ataturk University
HIV Infections, Hyperlipidemia
Genetic Predictors of Variability in the Drug-drug Interaction Between Darunavir/Ritonavir and Pravastatin
Pravastatin (Pravachol) is approved by the Food and Drug Administration (FDA) and is used to treat high cholesterol. Darunavir (Prezista) and ritonavir (Norvir) are approved by the Food and Drug Administration (FDA) to treat HIV…
- Trial name
- NCT00630734
- Testing
- Pravastatin, Darunavir, Ritonavir
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Healthy
Drug-drug Interaction (DDI) Study to Assess Effect of Itraconazole and Rifampicin Upon Olorofim
This is a Phase 1, single-centre, fixed-sequence, open label, drug-drug interaction study in 2 groups of healthy subjects. Group A: to evaluate the effects of itraconazole, a strong inhibitor of cytochrome P450 3A (CYP3A), upon…
- Trial name
- NCT04171739
- Testing
- Itraconazole oral solution, Rifampicin Oral Capsule, Olorofim
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- F2G Ltd
Polycystic Ovary Syndrome
Single Ascending Dose, First-in-Human Study on Safety, Tolerability and Pharmacokinetics of BAY1161116
This study will be conducted in a single center, double-blind with 6 dose escalation groups to evaluate the safety, tolerability, and pharmacokinetics of single ascending doses of BAY1161116.
- Trial name
- NCT03119077
- Testing
- BAY1161116, Itraconazole
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bayer
Healthy Volunteers
Evaluation of Effect of Vonoprazan on Midazolam Pharmacokinetics in Healthy Participants
To determine the time-dependent inhibition potential of repeated doses of oral vonoprazan on the pharmacokinetics (PK) of a single oral dose of midazolam, a sensitive cytochrome P450 3A4 (CYP3A4) substrate, in healthy…
- Trial name
- NCT04545944
- Testing
- Vonoprazan, Midazolam
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Phathom Pharmaceuticals, Inc.
Healthy Volunteers
Study to Evaluate the Effect of Repeat-Dose Rifampin on the Pharmacokinetics (PK) of PF-06651600
Study to Evaluate the Effect of Repeat-Dose Rifampin on the pharmacokinetics (PK) of PF-06651600.
- Trial name
- NCT04266509
- Testing
- PF-06651600, Rifampin
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Behavior Problems, Oppositional Defiant Disorder
The Effectiveness of Parent-Child Interaction Therapy (PCIT)
The purpose of this study was to investigate whether a type of parent-based intervention, Parent-Child Interaction Therapy will lower symptoms of behavior problems in young children more than treatment as usual.
- Conditions
- Behavior Problems, Oppositional Defiant Disorder, Conduct Disorder
- Trial name
- NCT01085305
- Testing
- Parent-Child Interaction Therapy, TAU
- Where
- 2 sites in Norway
- Volunteers
- 63 people
- Sponsor
- Norwegian University of Science and Technology
Social Interaction, Self Efficacy
Multi-user Touch Surfaces for Promoting Social Participation and Self-efficacy in Upper-limb Stroke Rehabilitation
The purpose of this study is to compare the efficacy of conventional therapy with a framework intervention for upper limb motor rehabilitation based on the promotion of self-efficacy and social participation/interaction through a…
- Conditions
- Social Interaction, Self Efficacy, Stroke, Motor Activity
- Trial name
- NCT05316766
- Testing
- Physical rehabilitation, Physical rehabilitation interactive table
- Where
- Portugal
- Volunteers
- 12 people
- Sponsor
- Universidade da Madeira
Healthy Volunteer
Relative Bioavailability and Drug-drug Interaction Study With MT-7117 and a Proton Pump Inhibitor
An open label, multicentre, randomised, 2-cohort, sequential and crossover study to assess the relative oral bioavailability of MT-7117 higher content tablets versus MT-7117 lower content tablets and the pharmacokinetics of…
- Trial name
- MT-7117 BA DDI (NCT03688022)
- Testing
- MT-7117, PPI, Acidic beverage
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tanabe Pharma America, Inc.
Hypertension
Drug-Drug Interaction Study Between HUC2-565-A and HUC2-565-B
The purpose of this study is to evaluate a pharmacokinetic drug interaction and safety.
- Trial name
- NCT06618079
- Testing
- HUC2-565-A, HUC2-565-A and HUC2-565-B, HUC2-565-B, HUC2-565-A and HUC2-565-B
- Where
- South Korea
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Huons Co., Ltd.
Hypertension(HTN)
Pharmacokinetic Interaction Between HGP0904, HGP0608 and HGP1405
The purpose of this study is to investigate the pharmacokinetic interaction and safety between HGP0904, HGP0608 and HGP1405 when administered alone and in combination in healthy male volunteers
- Trial name
- NCT02387554
- Testing
- HGP0904, HGP0608, HGP1405
- Where
- South Korea
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Hanmi Pharmaceutical Company Limited
Abdominal Pain (AP), Disorders of Gut-brain Interaction
Transauricular Neurostimulation for Abdominal Pain Due to DGBI
This single-site, open-label pilot study will evaluate transcutaneous auricular neurostimulation using the Sparrow Link device as a treatment for adolescents aged 12 to 18 years with abdominal pain related to disorders of…
- Trial name
- NCT07798180
- Testing
- Transcutaneous auricular neurostimulation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Nationwide Children's Hospital
HIV Infections
Drug Interactions of Amprenavir and Efavirenz, in Combination With a Second Protease Inhibitor, in HIV-Negative Volunteers
The purpose of this study is to measure the blood levels of amprenavir (APV) alone, APV combined with efavirenz (EFV), and APV/EFV combined with a third drug (nelfinavir [NFV], indinavir [IDV], ritonavir soft gel capsules [RTV…
- Trial name
- NCT00005762
- Testing
- Indinavir sulfate, Ritonavir, Amprenavir
- Where
- 8 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Vascular Graft Infection, Infectious Aortitis
China Aortic Infection and Graft Infection Study: An Ambispective Cohort
Vascular infections are uncommon but severe infections involving the arterial wall, vascular grafts, or endografts, and their diagnosis and management remain challenging.
- Conditions
- Vascular Graft Infection, Infectious Aortitis, Aortoenteric Fistula
- Trial name
- CAIGIS (NCT07847346)
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
T2DM
Drug-Drug Interaction Study of Chiglitazar in Healthy Subjects.
This Phase 1 open label study is being conducted to characterize the pharmacokinetic (PK) and safety profiles of Chiglitazar with Empagliflozin，Atorvastatin and Valsartan in healthy subjects.
- Trial name
- NCT05681273
- Testing
- Chiglitazar, Empagliflozin, Atorvastatin
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Chipscreen Biosciences, Ltd.
Healthy
Drug-drug Interaction Study with GLPG3970 and Sulfasalazine in Adult, Healthy Subjects
GLPG3970 will be given with sulfasalazine to investigate the effect of co-administration on the pharmacokinetics of sulfasalazine, and on the safety and tolerability of the drugs in healthy adult subjects.
- Trial name
- NCT04720183
- Testing
- Sulfasalazine, GLPG3970
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Lakefront Biotherapeutics NV
Racism
Addressing Microaggressions in Racially Charged Patient-provider Interactions: A Pilot Randomized Trial
Racial bias in medical care is a significant public health issue, with increased focus on microaggressions and the quality of patient-provider interactions.
- Trial name
- NCT04180956
- Testing
- Bias-reduction Intervention
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Washington
Mental Health Disorder
Social Cognition and Interaction Training (SCIT) for Taiwanese People With Severe Mental Illness
Social cognition dysfunction (including emotional perception, theory of mind, and attribution bias) is a common dysfunction in serious mental illness, which may influence their life roles and daily functions.
- Trial name
- NCT04428996
- Testing
- Social Cognition and Interaction Training (SCIT)
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Cheng-Kung University Hospital
Gestational Diabetes, Mobile Application
eHealth in Treatment of Gestational Diabetes (eMOMGDM)
The overall aim of the eMOM GDM-project is to develop and evaluate a novel system to clinical decision making and patient behavior change in treatment of GDM, combining diet, physical activity, sleep, heart rate (e.g.
- Trial name
- eMOMGDM (NCT04714762)
- Testing
- eMOM GDM application
- Where
- Finland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital