Clinical trials: Sodium Balance
Drug-induced QT Prolongation, Pharmacokinetics
Ability of Late Sodium or Calcium Current Block to Balance the ECG Effects of Potassium Current Block
The primary objective of this research study is to test the hypothesis that late sodium current blocking drugs (mexiletine or lidocaine) can attenuate the effect of hERG potassium channel blocking drugs (dofetilide) on…
- Conditions
- Drug-induced QT Prolongation, Pharmacokinetics, Pharmacodynamics
- Trial name
- NCT02308748
- Testing
- Dofetilide, Mexiletine, Lidocaine
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Food and Drug Administration (FDA)
Healthy Participants
Renal Salt Handling in Postural Tachycardia Syndrome Following Dietary Dopa Administration
The purpose of this study is to learn how plants can play a role in gain/loss of sodium in the urine and in the regulation of blood pressure.
- Trial name
- NCT01064739
- Testing
- Fava beans, Fixed Sodium Diet
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University