Clinical trials: Sodium Bicarbonate, open to volunteers
The Effects of Sodium Bicarbonate Supplementation on Endurance Performance in Recreational Female Runners
Sodium Bicarbonate Intake on Endurance Performance
Sodium bicarbonate (SB) is one of the ergogenic aids that enhance short-duration, high-intensity sports performance by improving the buffering system.
- Trial name
- NCT06826222
- Testing
- Sodium Bicarbonate (NaHCO3), Sodium Chloride
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Hypertension in Dialysis Patients
Sodium Bicarbonate in Intra-dialytic Hypertension in Chronic Hemodialysis Patients
The study is designed to diminish intra-dialytic hypertension in chrnic hemodialysis patients suffering from metabolic acidosis (low bicarbonate levels).
- Trial name
- NCT07231900
- Testing
- Sodium Bicarbonate (NaHCO3)
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Assaf-Harofeh Medical Center
Supplementation, Sports
Effects of β-alanine and Sodium Bicarbonate Supplementation on Physical Capacity and Biochemical Markers Concentrations
This randomized, double-blind, placebo-controlled, parallel-group study aims to evaluate the potential synergistic effect of beta-alanine (BA) and sodium bicarbonate (SB) supplementation, compared to their separate administration…
- Conditions
- Supplementation, Sports, Female Athletes
- Trial name
- NCT07092930
- Testing
- BA and SB supplementation, BA and PL2 supplementation, PL1 and SB supplementation
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Kidney Stones, Urolithiasis, Hypocitraturia, Nephrolithiasis
Sodium Bicarbonate as an Alternative to Potassium Citrate for Kidney Stones
Kidney stones affect 1 in every 11 people in the US each year. In patients with kidney stones who are prescribed medications for stone management, only 30.2% are adherent to a medication regime and even fewer, only 13.4 % are…
- Trial name
- NCT07408076
- Testing
- Potassium Citrate, Sodium Bicarbonate
- Where
- 6 sites in United States, Canada and 1 more
- Volunteers
- 30 people
- Sponsor
- University of California, Los Angeles
Hepatic Ischemia
Application of Sodium Bicarbonate Ringer's Solution in Laparoscopic Hepatectomy
Compared the effects of Sodium bicarbonate Ringer's solution and lactate Ringer's solution on the internal environment and hemodynamics of patients during laparoscopic liver resection, to observe the application prospect of…
- Trial name
- NCT05830136
- Testing
- sodium bicarbonate Ringer's solution
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Sport Performance, Acid Base Imbalance
Effects of Single Sodium Bicarbonate Supplementation on National-Level Finswimming Performance
This randomized, double-blind, placebo-controlled crossover trial will investigate the acute effects of sodium bicarbonate supplementation on performance, stroke biomechanics, and selected physiological and perceptual responses…
- Conditions
- Sport Performance, Acid Base Imbalance, Ergogenic Support, Sodium Bicarbonate
- Trial name
- NCT07135934
- Testing
- Sodium Bicarbonate (NaHCO3)
- Where
- Czechia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Palacky University
Exercise-Induced Fatigue, Athletic Performance
The Effect of Individual Sodium Citrate Consumption on Repeated Sprint Performance in Female Soccer Players
The aim of this research is to determine whether sodium citrate supplementation, taken at the best individual time, would improve repeated sprint performance in professional female soccer players.
- Conditions
- Exercise-Induced Fatigue, Athletic Performance, Soccer
- Trial name
- ITSCORE-F (NCT07737327)
- Testing
- Sodium Citrate Oral Product
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
End-stage Renal Disease (ESRD), Chronic Hemodialysis
Pilot Trial of Oral Sodium Bicarbonate Versus Higher Dialysate Bicarbonate in Hemodialysis Patients With Metabolic Acidosis
Metabolic acidosis is frequent in chronic hemodialysis patients and is associated with adverse clinical outcomes. Two commonly used strategies to correct acidosis are oral sodium bicarbonate supplementation and increasing the…
- Conditions
- End-stage Renal Disease (ESRD), Chronic Hemodialysis, Metabolic Acidosis
- Trial name
- Bicarbonate-HD (NCT07688434)
- Testing
- Oral sodium bicarbonate, Increased Dialysate Bicarbonate
- Where
- Tunisia
- Volunteers
- 37 people
- Sponsor
- University of Sfax
Chronic Kidney Disease
Neurovascular Regulation During Exercise in Humans With Chronic Kidney Disease: Sympatholysis in CKD
The goals of this project are to investigate the mechanisms and potential therapies related to exercise capacity in persons with chronic kidney disease (CKD).
- Trial name
- NCT05928936
- Testing
- Sodium Bicarbonate, Exercise Training
- Where
- 2 sites in United States
- Volunteers
- 156 people
- Sponsor
- Emory University
Renal Failure, Hemodialysis
Dial-Bicarb Trial: Effects of a Lower vs. Higher Concentration of Dialysate Bicarbonate
This is a pragmatic, two-arm, parallel-group, open-label, individual-randomized, superiority trial that will be conducted in hemodialysis units across Ontario.
- Trial name
- NCT06270134
- Testing
- Bicarbonate
- Volunteers
- 14,000 people
- Sponsor
- McMaster University
Myofacial Pain, Myofacial Pain Syndrome
Evaluation of the Effect of Adding Sodium Bicarbonate to Lidocaine in the Treatment of Myofascial Pain Syndrome
This study is designed to evaluate a method to improve the treatment of myofascial pain syndrome (MPS), a common condition that causes muscle pain, tenderness, and reduced movement due to the presence of trigger points in…
- Conditions
- Myofacial Pain, Myofacial Pain Syndrome, Myofacial Pain Syndromes, Trigger Point Pain, Myofascial
- Trial name
- BIC-LIDO-MPS (NCT07572994)
- Testing
- Lidocaine 2 %, Lidocaine + Sodium Bicarbonate
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Metabolic Acidosis
A Study of Tris-Hydroxymethyl Aminomethane (THAM) Versus Sodium Bicarbonate in Cardiac Surgical Patients
The purpose of this research is to determine if two commonly used medications to treat metabolic acidosis in the setting of cardiac surgery, sodium bicarbonate and THAM, are equivalent.
- Trial name
- NCT07424625
- Testing
- Sodium bicarbonate, Tris-hydroxymethyl Aminomethane
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Mayo Clinic
Periodontal Diseases
Periodontal Health and Sodium Bicarbonate Toothpaste
The goal of this clinical trial is to determine whether sodium bicarbonate fluoride toothpaste can help maintain periodontal health in adults who have undergone non-surgical periodontal treatment.
- Trial name
- NCT07274189
- Testing
- no treatment received, Periodontal treatment and OHI
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Plymouth
Acute Respiratory Failure, Acute Respiratory Distress Syndrome (ARDS)
The Feasibility of Pulmonary Perfusion Assessment Using Sodium Bicarbonate Contrast With Electrical Impedance Tomography: A Prospective Pilot Study
The goal of this observational pilot study is to learn if sodium bicarbonate can be used safely and effectively as a contrast agent to map lung blood flow using electrical impedance tomography (EIT) in adults on mechanical…
- Conditions
- Acute Respiratory Failure, Acute Respiratory Distress Syndrome (ARDS), Pneumonia, Critical Illness
- Trial name
- NCT07542366
- Where
- China
- Volunteers
- 41 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Uric Acid Stones
Impact of Sodium Bicarbonate on 24-hour Urine Parameters in Hypocitriuric and Uric Acid Stone Formers
The incidence of kidney stone disease continues to rise globally. Although the treatment of kidney stone disease has dramatically improved in recent years, surgical management remains invasive and expensive.
- Trial name
- NCT06335537
- Testing
- Potassium citrate, Sodium bicarbonate
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, Irvine
Acute Kidney Injury, Metabolic Acidosis
Sodium Bicarbonate for Critically Ill Patients With Metabolic Acidosis and Acute Kidney Injury
The study investigates whether sodium bicarbonate is able to reduce the occurrence of major adverse kidney events on day 90 (MAKE90) in critically ill patients with metabolic acidosis and acute kidney injury (AKI).
- Conditions
- Acute Kidney Injury, Metabolic Acidosis, Critical Illness
- Trial name
- ESCALATE (NCT07464431)
- Testing
- Sodium Bicarbonate 8.4% Solution for Injection, Balanced crystalloid solution
- Where
- Germany
- Volunteers
- 660 people
- Sponsor
- Universität Münster
Cholecystectomy, Laparoscopic, Ambulatory Surgical Procedures
Efficacy and Safety of Cocktail of Ropivacaine for Local Infiltration Analgesia in Patients Undergoing Laparoscopic Cholecystectomy
The goal of this clinical trial is to learn if the use of cocktail of ropivacaine,sodium bicarbonate and dexamethasone for incision local infiltration analgesia in patients undergoing ambulatory laparoscopic cholecystectomy is…
- Conditions
- Cholecystectomy, Laparoscopic, Ambulatory Surgical Procedures, Multimodal Analgesia
- Trial name
- NCT06819748
- Testing
- The cocktail of 0.5% ropivacaine ,5%sodium bicarbonate and 10 mg dexamethasone, 0.5% ropivacaine
- Where
- China
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Sichuan Provincial People's Hospital
Chronic Kidney Diseases, Metabolic Acidosis
Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD
Skeletal muscle metabolic health is critical for mobility and an underrecognized target of metabolic acidosis in chronic kidney disease.
- Conditions
- Chronic Kidney Diseases, Metabolic Acidosis, Fatigue, Physical Endurance
- Trial name
- Senergy-CKD (NCT04984226)
- Testing
- Sodium bicarbonate
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of California, Davis
Chronic Kidney Disease
The Role of Sodium Bicarbonate Enema in Improving Constipation and Reducing Uremic Toxins in Chronic Kidney Disease Patients.
Chronic kidney disease (CKD) is a progressive condition characterized by a gradual loss of kidney function, often resulting in the accumulation of metabolic waste products.
- Trial name
- NCT07394920
- Testing
- sodium bicarbonate enema
- Volunteers
- 100 people
- Sponsor
- Assiut University
Labour Dystocia
Oral Sodium Bicarbonate for the Prevention of Labour Dystocia
Sodium bicarbonate is often used by athletes to improve their muscle's ability to contract and power their activity. It works by decreasing the risk of lactic acid build-up, which causes cramping and fatigue.
- Trial name
- Labour-Aide (NCT06249061)
- Testing
- oral sodium bicarbonate
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Liz Darling