Clinical trials: Sodium Depletion
Hyponatremia
0.9% NaCl/Dextrose 5% vs 0.45% NaCl/Dextrose 5% as Maintenance Intravenous Fluids in Critically Ill Children
The primary objective of this study is to compare the mean serum sodium after 48 hours of therapy with either 0.45% NaCl/dextrose 5% or 0.9% NaCl/dextrose 5%, in critically ill children requiring IV maintenance fluid…
- Trial name
- NaCrICh (NCT01301274)
- Testing
- hypotonic, isotonic
- Where
- Argentina
- Volunteers
- 66 people
- Sponsor
- Hospital General de Niños Pedro de Elizalde
Complication of Surgical Procedure
Comparison of Infusion Methods for Hysteroscopic Procedures
This study is to perform a randomized controlled trial of comparing the manual syringe infusion method with the conventional pump infusion method to clarify if the manual syringe infusion method really needs less amount of…
- Trial name
- NCT02012010
- Testing
- Manual syringe infusion method, Pump infusion method
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Far Eastern Memorial Hospital
Hyponatremia, Syndrome of Inappropriate Antidiuresis
Protein Supplementation in Hyponatremia Due to the Syndrome of Inappropriate Antidiuresis
The goal of this study is to assess the impact of protein supplementation on hyponatremia caused by the syndrome of inappropriate antidiuresis during hospitalization.
- Trial name
- TREASUREx (NCT06821802)
- Testing
- Moltein PURE Protein Powder, Fluid restriction
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- University Hospital, Basel, Switzerland
Electrolyte Depletion, Stoma Ileostomy
Evaluation of the Normal Range of Urinary Sodium Levels in Healthy Newborn Babies
Oral sodium supplementation is currently administered in cases of poor weight gain in infants particularly in patients who have undergone gastrointestinal surgical procedures.
- Conditions
- Electrolyte Depletion, Stoma Ileostomy, Stoma Colostomy, Growth Failure
- Trial name
- USALTI (NCT03016195)
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
The Patients Suffered With Sellar Diseases, The Fluid and Electrolyte Imbalance Happened After Surgery
Disturbance of Water and Sodium Metabolism After Surgery of Sellar Lesions, and Correspond Clinical Strategy
The fluid and electrolyte imbalance (FEI) is pretty common encountered during the clinical process of patients suffered sellar lesions.
- Trial name
- NCT01406041
- Testing
- Chemical and physical detection
- Where
- China
- Volunteers
- 350 people
- Sponsor
- Southern Medical University, China
Hyponatremia, Dengue
Prevalence of Hyponatremia in Dengue Infected Patients: Relationship With Systemic Inflammation.
Prospective cohort study in patients with newly diagnosed dengue infection at Hospital Posadas in Argentina, between January 1, 2016, and November 1, 2023. Diagnosis was confirmed by IgM serology or PCR.
- Conditions
- Hyponatremia, Dengue, Inflammation
- Trial name
- HINDIP (NCT06109532)
- Testing
- hyponatremia
- Where
- 2 sites in Argentina
- Volunteers
- 530 people
- Sponsor
- Hospital Nacional Profesor Alejandro Posadas
Hyponatremia
Post Operative Hyponatremia in the Renal Transplant Population
This study is designed to determine the causes of low sodium (salt) in the body fluids outside the cells for patients who have received a kidney transplant at the Mayo Clinic of Florida.
- Trial name
- NCT01456832
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Mayo Clinic
Hyponatremia, Hypertension
Protein Supplementation in Thiazide-induced Hyponatremia
High blood pressure is very common among elderly Canadians. Clinical trials show clear benefit from lowering blood pressure in hypertensive elderly patients.
- Conditions
- Hyponatremia, Hypertension, Blood Pressure
- Trial name
- NCT02614807
- Testing
- Nepro
- Where
- Canada
- Sponsor
- Ottawa Hospital Research Institute
Proton Pump Inhibitor Adverse Reaction, Delirium
Delirium Related to Proton Pump Inhibitors Use
Delirium is a frequent and severe condition, especially in old adults. Its occurrence is due to a drug in 30% of cases. In 2009, the French national health authority (Haute Autorité de Santé) mentioned proton pump inhibitors…
- Conditions
- Proton Pump Inhibitor Adverse Reaction, Delirium, Hyponatremia
- Trial name
- NCT05815550
- Testing
- PPI
- Where
- France
- Volunteers
- 19,081 people
- Sponsor
- University Hospital, Caen
Hyponatremia
Comparison of Ringer Lactate and Isotonic Acetate Solution as Perioperative Maintenance Fluid for Children
In children fluids are supplemented during surgery to provide volume, to maintain blood glucose levels, electrolyte balance and to meet the ongoing fluid losses during surgery.
- Trial name
- NCT02936167
- Testing
- Ringer Lactate, Plasmalyte
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
SIADH, Non-SIADH Hyponatremia
Post-Authorisation Safety Study of Samsca (Tolvaptan) Used in Routine Medical Practice
A Drug Utilisation Survey is performed to monitor and document the drug utilisation patterns of Samsca in routine medical practice.
- Conditions
- SIADH, Non-SIADH Hyponatremia, Non-Hyponatremia
- Trial name
- NCT01228682
- Testing
- Tolvaptan
- Where
- 47 sites in Denmark, Germany and 5 more
- Volunteers
- 200 people
- Sponsor
- Otsuka Frankfurt Research Institute GmbH
Hyponatremia
Hyponatremia in the Elderly: Benefit From a Change in Drug Therapy?
Mild hyponatremia is the commonest electrolyte imbalance in the older population. Recently, association between hyponatremia and bone fractures in the ambulatory elderly has been shown.
- Trial name
- NATRIPHAR (NCT01212211)
- Testing
- change in drug therapy
- Where
- France
- Volunteers
- 18 people
- Sponsor
- University Hospital, Caen
Hyponatremia in Elderly
Hyponatremia in Elderly Patients With Fractures Around the Hip.
Hyponatremia was defined as a serum sodium concentration <135 mmol/L that occurred at least once during a patient's hospital stay from admission to discharge.
- Trial name
- NCT03456492
- Testing
- serum sodium
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
SIAD - Syndrome of Inappropriate Antidiuresis, Hyponatremia
Effects of Intravenous [Pyr1]Apelin-13 on Healthy Volunteers With Artificially Induced SIAD
Hyponatremia is a common electrolyte imbalance which often results from hormonal disregulation. The study aims to investigate whether the apelin hormone, which plays a role in regulating salt and water balance in the body, can be…
- Trial name
- ESCAPE (NCT06277336)
- Testing
- Apelin Low Dose, Apelin High Dose, Selected Apelin Dose
- Where
- Switzerland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Subarachnoid Hemorrhage
Study of Changes in CSF Ionic Composition After Aneurysmal Meningeal Hemorrhage
Hyponatremia is a frequent complication of subarachnoid hemorrhage (SAH) with a prevalence of 30 to 50% in patients with this condition.
- Trial name
- ION_SAH (NCT05942755)
- Testing
- Concurrent evaluation of blood and CSF ionograms to determine if there is a correlation between CSF change and the development of hyoponatremia between day 0 and day 14.
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Hospices Civils de Lyon
Post-operative Pain
Investigation of the Effect of Distention Medium Temperature on Image Quality, Hyponatremia Risk, and Post-operative Pain in Operative Hysteroscopy
Minimally invasive applications are seen as the gold standard in today's gynecology practice and are frequently preferred by both patients and physicians.
- Trial name
- NCT05973045
- Testing
- Operative Hysteroscopy 24 Centigrade Degree, Operative Hysteroscopy 37 Centigrade Degree
- Where
- Turkey (Türkiye)
- Volunteers
- 244 people
- Sponsor
- Ege University
Hyponatremia, Premature
Early Sodium Intake in Preterm Newborns
Hyponatremia is a common complication among preterm infants, renal losses of sodium contribute to the development of hyponatremia in preterm newborns. Sodium imbalances impact in newborns outcome.
- Trial name
- NCT04035564
- Testing
- Sodium < 1mEq/kg/day, Sodium 5mEq/kg/day
- Where
- Mexico
- Volunteers
- 52 people
- Sponsor
- Hospital del Niño "Dr. Federico Gomez Santos"
Thiazide Associated Hyponatremia
Validation of New Diagnostic Indices to Simplify Hyponatremia Therapy Assessment in Patients on Thiazide Diuretics
This study is looking at two new parameters, aSID and ChU, to see if these can help physicians to distinguish between different causes of low sodium levels (hyponatremia) in Patients taking a medicament against high blood…
- Trial name
- NCT06381934
- Testing
- Standard Care, aSID/ChU Guided Therapy
- Where
- Switzerland
- Volunteers
- 136 people
- Sponsor
- University Hospital, Basel, Switzerland
Hyponatremia
Analysis of Factors Determining Increase of Serum Sodium in Hyponatremic Patients
The aim of this study is to further analyse the dataset of the Hyponatremia Registry, a multicenter, prospective, observational study conducted between September 2020 and February 2013 in the United States of America and the…
- Trial name
- NCT05277584
- Where
- Germany
- Volunteers
- 3,460 people
- Sponsor
- University of Cologne
Ileostomy - Stoma, Short Bowel Syndrome
Osmolality of Oral Supplements and Ileostomy Output
This double-blinded, active comparator, cross-over intervention study tested the impact of two different oral supplements on ileostomy output volume and urinary sodium excretion and intestinal aquaporin expression in eight…
- Conditions
- Ileostomy - Stoma, Short Bowel Syndrome, Sodium Depletion, Nutritional Deficiency
- Trial name
- NCT03348709
- Testing
- Isoosmolar, Hyperosmolar
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- University of Aarhus