Clinical trials: Sodium Imbalance
Hypertension, Sodium Excess
Effects of Salt on Serum Osmolarity and Hemodynamics Parameters
Diets containing excessive salt (>12 g/day) have negative effects on kidney and cardiovascular system. Considering this known fact, the investigators aimed to study if the amount of the water taken with excessive salt had any…
- Conditions
- Hypertension, Sodium Excess, Oxidative Stress, Inflammation
- Trial name
- NCT03314727
- Testing
- High salt (NaCl) intake
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Koç University
Hyponatremias, Water Intoxication
"SALT Trial" Study of Ascending Levels of Tolvaptan in Hyponatremia
This study's purpose is to determine whether tolvaptan can safely and effectively return the body's balance of sodium and water toward normal, and to characterize and quantify the potential clinical benefits of this treatment.
- Conditions
- Hyponatremias, Water Intoxication, Inappropriate ADH Syndrome, Water-Electrolyte Imbalances
- Trial name
- NCT00072683
- Testing
- tolvaptan
- Where
- 23 sites in United States
- Volunteers
- 205 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Metabolic Acidosis
A Study of Tris-Hydroxymethyl Aminomethane (THAM) Versus Sodium Bicarbonate in Cardiac Surgical Patients
The purpose of this research is to determine if two commonly used medications to treat metabolic acidosis in the setting of cardiac surgery, sodium bicarbonate and THAM, are equivalent.
- Trial name
- NCT07424625
- Testing
- Sodium bicarbonate, Tris-hydroxymethyl Aminomethane
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Mayo Clinic
Nocturia
Validation of Capillary Serum Sodium Levels
Prospective interventional study to determine sodium levels in capillary blood via finger prick. The goal is to determine if this technique is suitable and equal to a standard venous blood collection for the analysis of blood…
- Trial name
- NCT05414279
- Testing
- Sodium determination
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Hyperkalemia
SZC Versus SPS for Treatment of Hyperkalemia in Hemodialysis Patients
This study aims to compare the effects of Sodium Zirconium Cyclosilicate versus Sodium Polystyrene Sulfonate for treatment of hyperkalemia in patients undergoing regular hemodialysis.
- Trial name
- NCT06029179
- Testing
- sodium zirconium cyclosilicate (SZC), sodium polystyrene sulfonate
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Alexandria University