Clinical trials: Sodium Lactate
GLUT1 Deficiency Syndrome, GLUT1DS1
Sodium Lactate Infusion in GLUT1DS Patients
This study investigates the effect of lactate infusion on epileptic discharges on EEG and seizure frequency in glucose transporter 1 deficiency syndrome (GLUT1DS) patients.
- Conditions
- GLUT1 Deficiency Syndrome, GLUT1DS1, GLUT1DS2, Epilepsy
- Trial name
- NCT04112862
- Testing
- sodiumlactate
- Where
- Netherlands
- Volunteers
- 2 people
- Sponsor
- Radboud University Medical Center
Head Trauma
Preventive Sodium Lactate and Traumatic Brain Injury
The goal of this study is to evaluate the effect of preventive intravenous infusion of half molar sodium lactate on the onset of hypertensive intracranial episodes in severe head trauma.
- Trial name
- NCT00995683
- Testing
- half molar sodium lactate, isotonic sodium chloride
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Institut d'Anesthesiologie des Alpes Maritimes
Brain Injuries, Traumatic
Exogenous Sodium Lactate Infusion in Traumatic Brain Injury (ELI-TBI)
Metabolic crisis is a state of energy insufficiency due to impaired mitochondrial function as indicated by cerebral microdialysis lactate/pyruvate ratio (LPR).
- Trial name
- ELI-TBI (NCT02776488)
- Testing
- Sodium Lactate
- Where
- United States
- Sponsor
- University of California, Los Angeles
Lumbar Fusion Surgery, Elderly Patients
Clinical Impact of Different Crystalloid Solution on Early Biomarkers of Kidney Injury After Lumbar Fusion Surgery in Elderly Patients
This study aims to compare the effects of sodium acetate Ringer's solution versus sodium lactate Ringer's solution on early postoperative renal function indicators, renal injury biomarkers, and acute kidney injury (AKI) in…
- Conditions
- Lumbar Fusion Surgery, Elderly Patients, Sodium Acetate Ringer's Solution, Sodium Lactate Ringer's Solution
- Trial name
- NCT07542353
- Testing
- Sodium Acetate Ringer's Solution (Group A), Sodium Lactate Ringer's Solution (Group B)
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Xianping Wu
Cognition, Sodium Bicarbonate
Exercise-Induced Lactate and Cognitive Function (ExLBC)
A single bout of exercise can rapidly improve cognitive functions including memory, attention, and executive functions, which help us navigate through everyday life.
- Conditions
- Cognition, Sodium Bicarbonate, Lactate, Exercise
- Trial name
- NCT06817681
- Testing
- Sodium Bicarbonate (NaHCO3)
- Where
- 2 sites in Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- McMaster University
Sodium Lactate, Intracranial Hypertension
Sodium Lactate and Brain Relaxation (LSD)
Resection surgery of brain tumors by craniotomy requires efficient brain relaxation intraoperatively in order to avoid injuries caused by the brain retractors (such as ischemic-reperfusion and cerebral oedema).
- Conditions
- Sodium Lactate, Intracranial Hypertension, Brain Relaxation
- Trial name
- LSD (NCT04488874)
- Testing
- Sodium Lactate, Mannitol 20% Infusion
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Major Depressive Disorder
Feasibility of Conducting a Clinical Trial Assessing Efficacy of Lactate as Adjunctive Therapy in Patients With Major Depressive Disorder
The goal of this clinical trial is to test the efficacy of lactate (a natural substance) in combination with standard antidepressant treatment, in patients hospitalized for a major depressive episode.
- Trial name
- NCT06168175
- Testing
- Sodium lactate
- Volunteers
- 46 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Metabolic Ketoacidosis, Ketoacidemia
0.9% Saline Versus Balanced Solutions in Severe Diabetic Ketoacidosis
Severe diabetic ketoacidosis (DKA) is a potentially serious complication of diabetes mellitus. The treatment regimen is based on insulin and rehydration. The choice of rehydration solution is a question that remains open.
- Conditions
- Metabolic Ketoacidosis, Ketoacidemia, Acetonemia, Acetonuria
- Trial name
- NCT05808972
- Testing
- Sodium chloride 0.9% (SC), Ringer lactate (RL)
- Where
- Tunisia
- Volunteers
- 92 people
- Sponsor
- Tunis University