Clinical trials: Sodium-sensitivity
Dentin Hypersensitivity
Effect of Using Different Varnishes on Dentin Hypersensitivity; Na Fluoride and Nano-silver Fluoride
2 different varnishes will be used to test their effectiveness in controlling teeth hypersensitivity in adult patient.
- Trial name
- NCT04731766
- Testing
- Citrine 5 % sodium fluoride, concocted nano-silver fluoride
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Nayera Hassanien Mohamed
Dentin Sensitivity
Clinical Efficacy in Relieving Dentin Hypersensitivity of Nanohydroxyapatite-Containing Toothpastes and Cream
This study will investigate the effectiveness of nanohydroxyapatite (nano-HAP)-containing toothpastes and cream to relieve dentin hypersensitivity, comparing it with those of a commercial desensitizing dentifrice containing…
- Trial name
- NCT02918617
- Testing
- Control toothpaste containing Novamin® technology, Control toothpaste containing 1500 ppm fluoride as MFP, Test toothpaste with nano-HAP (high concentration)
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Asthma
A Study to Assess the Effect of Montelukast Sodium With Concomitant Administration of Inhaled Budesonide in Asthmatic Patients (0476-075)
A study to assess the clinical effect of montelukast sodium with concomitant administration of inhaled budesonide in asthmatic patients.
- Trial name
- NCT00140946
- Testing
- MK0476; montelukast sodium/Duration of Treatment: 16 weeks
- Volunteers
- 546 people
- Sponsor
- Organon and Co
Bronchial Asthma
Study of Efficacy of Sodium Valproate in Therapy of Bronchial Asthma
The purpose of this study is to determine whether antiepileptic drug sodium valproate is effective in the treatment of chronic asthma.
- Trial name
- NCT00153270
- Testing
- Sodium Valproate
- Volunteers
- 46 people
- Sponsor
- Centre of Chinese Medicine, Georgia
Asthma
The Singulair® add-on Study Effectiveness of Adding Montelukast to Inhaled Corticosteroids in Adult Subjects With Uncontrolled Asthma (0476-384)
The purpose of this study is to evaluate the effectiveness of adding Montelukast Sodium (singulair®) 10 mg per day to inhaled corticosteroids in adult subjects with uncontrolled asthma.
- Trial name
- SAS (NCT00755794)
- Testing
- montelukast sodium
- Volunteers
- 800 people
- Sponsor
- Organon and Co
Dentin Sensitivity
Effectiveness of Arginin and Potassium Nitrate Dentifrices in Dentin Hypersensitivity Therapy
Introduction: Dentin hypersensitivity (DH) could be defined as a brief and sharp pain in response to thermical, chemical, tactile and osmotic stimuli, which cannot be attributed to any dental condition or pathology.
- Trial name
- NCT02829879
- Testing
- 8% arginine/1450ppm sodium monofluorophosphate dentifrice, 5% potassium nitrate/2500ppm sodium fluoride dentifrice
- Where
- Chile
- Volunteers
- 50 people
- Sponsor
- University of Chile
Hypertension
Blood Pressure Response to Sodium in the Diet
Previous studies have demonstrated that single nucleotide polymorphisms (SNPs) of the sodium-bicarbonate co-transporter gene (SLC4A5) are associated with hypertension.
- Trial name
- NCT01899495
- Testing
- High sodium diet and low sodium diet
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Sensitivity, Tooth
Reduction of Dentine Hypersensitivity After Use of Different Dentifrices
To assess the impact of the use of 5% Calcium Sodium Phosphosilicate or 8% Arginine dentifrices on dentinal hypersensitivity following non-surgical periodontal therapy in patients with periodontitis.
- Trial name
- Dentrifices (NCT06273930)
- Testing
- 5% CALCIUM SODIUM PHOSPHOSILICATE, 8% Arginine
- Where
- Pakistan
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Asthma
Bioequivalency Study of Montelukast Chewable 5 mg Tablets Under Fed Conditions
The objective of this study was to prove the bioequivalence of Montelukast Chewable Tablet under fed conditions
- Trial name
- NCT01659892
- Testing
- Montelukast, Singulair
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Hand and Foot Syndrome
Effect of Topical Diclofenac on Clinical Outcome in Breast Cancer Patients Treated With Capecitabine
The aim of the study is to evaluate the efficacy of using combination of Urea-based cream (CARBAMIDE®) and topical diclofenac (VOLTAREN®) Emulgel 1% for improving the incidence of Hand-foot syndrome in histologically proven…
- Trial name
- NCT05641246
- Testing
- (CARBAMIDE®), (VOLTAREN®) Emulgel 1%
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- German University in Cairo
Dentin Hypersensitivity
Effectiveness of Calcium Silicate and Sodium Fluoride Nanoparticles in The Management of Dentin Hypersensitivity
This study will be performed to assess the effect of inert prepared tooth paste loaded with Calcium Silicate Nanoparticles (CSNPs) and compare it to another one containing Sodium Fluoride Nanoparticles in the management of…
- Trial name
- NCT06557980
- Testing
- toothpaste
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Minia University
Tooth Sensitivity
Effect of CPP-ACP Associated With NaF or SnF₂ on Post-Bleaching Tooth Sensitivity
This randomized, triple-blind, placebo-controlled clinical trial aims to evaluate the efficacy of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) associated with sodium fluoride (NaF) or stannous fluoride (SnF₂) in…
- Trial name
- NCT07506850
- Testing
- CPP-ACPF, CPP-ACP+SnF2
- Where
- Brazil
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Hypertension,Essential
The Significance of Sodium Balance and the Value of Salt-blood Test in Identifying Salt Sensitive Patients
This is a randomized controlled trial with 72 patients with hypertension examining the effects on blood pressure of sodium restriction and whether the blood analysis Salt-blood test is associated to a decrease in blood pressure.
- Trial name
- VASA (NCT05165823)
- Testing
- Sodium restriction
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Regional Hospital Holstebro
Moderate Asthma
Safety and Efficacy Study of the Use of Sodium Pyruvate Bronchodilation in Asthmatics
Sodium pyruvate in sodium chloride solution will be delivered by nebulization to the lungs. It is believed that this administration will produce bronchodilation in asthmatics as determined by improvement in FEV1.
- Trial name
- NCT00262652
- Testing
- sodium pyruvate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Emphycorp
Asthma, COPD
A Pilot Study of Montelukast Sodium (Singulair) in Older Adults With Asthma or Chronic Obstructive Pulmonary Disease
This randomized, double-blind, placebo-controlled trial assessed the efficacy of montelukast in the treatment of adults ≥50 years of age with persistent asthma and/or COPD.
- Trial name
- NCT00162864
- Testing
- montelukast sodium
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Kaiser Permanente
Chemotherapy-induced Peripheral Neuropathy, Recurrent Ovarian Carcinoma
High Dose Inorganic Selenium for Preventing Chemotherapy Induced Peripheral Neuropathy
This study aims to evaluate the safety and efficacy of high dose inorganic selenium in preventing and relieving chemotherapy-induced peripheral neuropathy (CIPN) in platinum-sensitive recurrent ovarian, fallopian, or primary…
- Conditions
- Chemotherapy-induced Peripheral Neuropathy, Recurrent Ovarian Carcinoma, Ovarian Cancer, Fallopian Tube Cancer
- Trial name
- SELENIUM (NCT04201561)
- Testing
- sodium selenite pentahydrate, Normal saline, Chemotherapy
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Seoul National University Hospital
Asthma
Bioequivalency Study of Montelukast 10 mg Tablets Under Fasted Conditions
The objective of this study was to prove the bioequivalence of Montelukast Tablet under fasted conditions
- Trial name
- NCT01659931
- Testing
- Montelukast, Singulair
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Prediabetes, Impaired Fasting Glucose
Effect of Dapagliflozin on Insulin Secretion and Insulin Sensitivity in Patients With Prediabetes
Prediabetes is a term that refers to alterations in glucose homeostasis, including impaired fasting glucose (IFG), impaired glucose tolerance (IGT) or both, involving a higher risk of progression type 2 diabetes mellitus (T2DM).
- Conditions
- Prediabetes, Impaired Fasting Glucose, Impaired Glucose Tolerance
- Trial name
- NCT02700334
- Testing
- Dapagliflozin
- Where
- Mexico
- Volunteers
- 24 people
- Sponsor
- University of Guadalajara
Allergic Conjunctivitis
Evaluation of the Efficacy of Topical Ophthalmic Steroids in a Modified Conjunctival Allergen Challenge (CAC) Model
The purpose of this study is to evaluate the effectiveness of the modified Conjunctival Allergen Challenge (CAC) and observe how the produced allergic inflammation reacts to treatment with a proven ocular anti-inflammatory…
- Trial name
- NCT01534195
- Testing
- Prednisolone Sodium Phosphate Ophthalmic Solution 1%, Tears Naturale II Ophthalmic Solution
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- ORA, Inc.
Eczema, Atopic Dermatitis
Sodium in the Skin and Atopic Dermatitis
The goal of this observational study is to understand factors associated with skin sodium storage in healthy adults and people with atopic dermatitis ages 50 and above.
- Trial name
- SIS-AD (NCT06998446)
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco