Clinical trials: Soft Contact Lenses
- Condition Soft Contact Lenses
- Funder type Industry (pharma, biotech, devices)
- Accepts healthy volunteers yes
Visual Acuity
Evaluation of Toric Soft Contact Lenses Containing a Chromophore to Block High-Energy Visible Light
This will be a 4-visit, randomized, controlled, single-masked, bilateral wear, dispensing, 2-treament, 2-sequence, 3-period crossover study to evalulate overall vision and comfort..
- Trial name
- NCT05344560
- Testing
- soft contact lens in senofilcon A (C3) with HEVL-blocking chromophore, ACUVUE OASYS 1-Day for Astigmatism
- Where
- 10 sites in United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Evaluating Accommodative Responses of Soft Contact Lenses for Myopia Control
This is a bilateral, non-dispensing, randomized, controlled, double-masked, 7x7 cross-over study. Each subject will be bilaterally fitted with one of the 7 test articles in each of the 7 periods for a total of four visits.
- Trial name
- NCT03635528
- Testing
- Test Lens 1, Test Lens 2, Test Lens 3
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Ametropia
Evaluation of Monthly Replacement Lenses in Habitual Soft Contact Lens Wearers Who Report Frequent Digital Devise Use
To evaluate the clinical performance of two monthly silicone hydrogel contact lenses in habitual wearers of frequent replacement (FRP) lenses when worn for 1-month.
- Trial name
- NCT05166902
- Testing
- Lens A (comfilcon A lens), Lens B (lehfilcon A lens)
- Where
- 4 sites in United States, Canada
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Ametropia
Endothelial Bleb Response With Toric Lenses
Evaluate the short-term corneal response of oxygen deprivation when using toric contact lenses. The response will be noted by endothelial bleb formation in both open eye and closed eye state.
- Trial name
- NCT00630305
- Testing
- alphafilcon A toric, lotrafilcon B toric, senofilcon A toric
- Where
- Australia
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Ametropia, Myopia
Apioc Contact Lens Feasibility
This clinical trial will document the feasibility of the Apioc lens design by assessing which lens shape parameters yield successful on-eye-fit and movement of the Apioc contact lens design and evaluate the subjectively-reported…
- Conditions
- Ametropia, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT03688672
- Testing
- Apioc Contact Lens Design
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lentechs, LLC
Visual Acuity
Visual Performance of Soft Contact Lenses With Myopia Control Optics
This is a multi-site, bilateral, dispensing, randomized, controlled, single-masked, 3x3 crossover study with a run-in period.
- Trial name
- NCT05141448
- Testing
- 1-Day Acuvue Moist, EMO-118, EMO-114
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Astigmatism Bilateral
Comparison of Two Daily Disposable Soft Contact Lenses
The aim of this study was to investigate the short-term clinical performance and subjective acceptance of the two study lenses.
- Trial name
- NCT03779503
- Testing
- midafilcon A, somofilcon A
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Presbyopia Condition
A Randomized, Active-Controlled, Double-Masked, Crossover Study to Evaluate the Clinical Performance of Deseyne (Vifilcon C) Daily Disposable Soft Contact Lens for Presbyopia Extended Depth of Focus (EDOF)
The goal of this clinical trial is to learn if the contact lens we are testing will work to extend the range of clear focus at distance to provide an increase in clear vision at closer ranges without the additional need for…
- Trial name
- EDOF (NCT06698731)
- Testing
- Test lens, Control lens
- Where
- 3 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Bruno Vision Care
Visual Acuity
Evaluation of Marketed Soft Contact Lenses
This is a bilateral, 2-week dispensing, non-randomized, controlled, single-masked, single-arm study to evaluate overall vision and comfort
- Trial name
- NCT05201807
- Testing
- Dailies Total 1 (DT1)
- Where
- 4 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
A Comparison of Two Daily Disposable Soft Contact Lenses
Approximately 120 subjects will be comparing two soft contact lenses for one week each.
- Trial name
- NCT02427477
- Testing
- senofilcon A, delefilcon A
- Where
- 6 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Contact Lens Care
Evaluation of an Investigational Multi-Purpose Disinfecting Solution for the Care of Soft Contact Lenses in Symptomatic Patients
The objective of the study was to clinically evaluate the safety and effectiveness of a new multi-purpose disinfecting solution for soft contact lenses in patients who experience discomfort with their contact lenses.
- Trial name
- NCT00382603
- Testing
- OptiFree Multi-Purpose Disinfecting Solution
- Where
- United States
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Presbyopia
Extended Depth of Focus Contact Lenses for Presbyopia
VTI has an FDA cleared soft contact lens product. Its optical design creates an enhanced depth of focus (EDOF), which provides clear distance, intermediate, and near vision.
- Trial name
- NCT05495971
- Testing
- NaturalVue Multifocal
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Visioneering Technologies, Inc
Refractive Error - Myopia Bilateral
Study to Evaluate the Clinical Performance of Deseyne (Vifilcon C) Daily Disposable Soft Contact Lens
This clinical study is to provide clinical performance data comparing the test lens (Deseyne [vifilcon C] daily disposable soft contact lens) to a control lens (1-Day Acuvue Moist [etafilcon A] daily disposable soft contact lens)…
- Trial name
- NCT05927753
- Testing
- Deseyne Daily Disposable Contact Lens (Test Device)
- Where
- 3 sites in United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Bruno Vision Care
Myopia
Silicone Hydrogel Soft Contact Lens 7-Day Extended Wear Basis
The objective of this study is to evaluate the safety and effectiveness of the Bausch + Lomb samfilcon A soft (hydrophilic) contact lens, a new silicone hydrogel contact lens, compared to the Bausch + Lomb PureVision® soft…
- Trial name
- NCT02939950
- Testing
- Bausch + Lomb Samfilcon A Soft Contact Lens, Bausch + Lomb Pure Vision Soft Contact Lens
- Where
- United States
- Volunteers
- 816 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Refractive Errors
Clinical Assessment of a Daily Disposable Soft Silicone Hydrogel Contact Lens
The purpose of this study is to assess the clinical performance of DAILIES TOTAL1® spherical soft contact lenses over approximately 1 week of daily wear.
- Trial name
- NCT06044948
- Testing
- Delefilcon A contact lenses
- Where
- 6 sites in United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Myopia
Evaluation of The Clinical Acceptance of Soft Contact Lenses for Myopia Control
The main objective of the study was to evaluate the clinical acceptance of soft contact lenses for Myopia control.
- Trial name
- NCT04709237
- Testing
- omafilcon A control lens, omafilcon A test lens 1, omafilcon A test lens 2
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Presbyopia, Refractive Errors
Apioc Presbyopic Contact Lens
In this study, you will wear an invesetigational contact lens, Apioc-P or Apioc-PT, the way you wear your current contact lenses for approximately one month (no more than 35 days).
- Trial name
- NCT04437732
- Testing
- Apioc-P and Apioc-PT Contact Lens Design
- Where
- 2 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Lentechs, LLC
Astigmatism
Evaluate the Safety and Effectiveness of the Biotrue ONEday for Astigmatism
Comparing Test Lens for Astigmatism Soft Contact Lens (Test) to 1-Day Control for Astigmatism contact lenses (Control).
- Trial name
- NCT03681808
- Testing
- Control, Test
- Where
- 13 sites in United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Hyperopia
Clinical Evaluation of Two Frequent Replacement Soft Spherical Contact Lenses
This was a single-blind (participant masked), interventional, prospective, direct refit, bilateral wear short-term fitting study.
- Trial name
- NCT05656885
- Testing
- Lens A, Lens B
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Performance and Safety of Silicone Hydrogel Soft Contact Lenses
To demonstrate substantial equivalence of the new Silicone Hydrogel Soft Contact Lenses(SHSCL) to the commercially available ACUVUE® VITA™ contact lens
- Trial name
- NCT04226560
- Testing
- 41% Silicone Hydrogel Soft Contact Lenses(SHSCL), ACUVUE® VITA™ (senofilcon C) Brand (Soft) Contact Lens, Contact Lens Care Product
- Where
- Taiwan
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- ApexLens Co., Ltd.