Clinical trials: Soft Contact Lenses
Contact Lens Wear
A Study to Evaluate the Safety and Effectiveness of a Silicone Hydrogel Custom Contact Lens When Compared to Alden Optical HP Sphere Lens
This study is to evaluate the safety and efficacy of Bausch + Lomb custom samfilcon B (test) lens compared to the hioxifilcon D, 54% water, Alden Optical HP Sphere (control) lens when worn by participants who wear soft contact…
- Trial name
- NCT03897712
- Testing
- Custom Samfilcon B Contact Lenses, Alden Optical HP Sphere Contact Lens, ReNu MultiPlus Lubricating and Rewetting Drops
- Where
- 7 sites in United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Ocular Surface Disease
Comparison Between Lathe Cut Versus Cast Molding Soft Contact Lens Technique on Ocular Surface Integrity
"Comparison between Lathe Cut versus Cast Molding Soft Contact Lens Technique on Ocular Surface Integrity" investigates the impact of two different manufacturing methods on the health and integrity of the ocular surface.
- Trial name
- NCT06495112
- Testing
- Soft contact lens with lathe cut technique Lathe, Soft contact lens with cast molding technique
- Where
- Pakistan
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Superior University
Astigmatism, Myopia
Short-term Study of Two Soft Contact Lenses in Wearers With Low Astigmatism
The primary objective of the study is to evaluate and compare the performance of two soft contact lens.
- Conditions
- Astigmatism, Myopia, Hyperopia
- Trial name
- NCT06873048
- Testing
- Control Contact Lens (stenfilcon A Sphere), Test Contact Lens (stenfilcon A Toric)
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- CooperVision International Limited (CVIL)
Myopia
Dual-focus Soft Contact Lenses for Controlling Rapid Progressive Myopia in Young Adults
This study aims to evaluate the effectiveness and acceptability of dual-focus soft contact lenses in controlling rapid myopia progression in adults through a randomized controlled trial.
- Trial name
- NCT06528860
- Testing
- MiSight® 1 day soft contact lenses, Proclear® 1 day soft contact lenses
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Astigmatism
Effect of Eye Movement on Toric Lens Orientation and Visual Acuity
The relative performance of a new toric soft contact lens against toric contact lenses currently available in market, specifically for visual acuity and lens orientation.
- Trial name
- NCT00584831
- Testing
- senofilcon A, balafilcon A, omafilcon A
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Evaluation of Deposits on Contact Lenses Worn Extended Wear
The purpose of this study was to measure lipid deposits on commercially marketed contact lenses when worn on an extended wear (overnight) basis for 7 days.
- Trial name
- NCT00725530
- Testing
- balafilcon A contact lens (PureVision), etafilcon A contact lens (Acuvue2)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Alcon Research
Visual Acuity
Evaluating Visual Acuity and Initial Fit Performance of Two Soft Contact Lenses
This is a multi-center, randomized, controlled, double-masked, 2x2 cross-over, non-dispensing study to compare visual acuity and lens fit performance.
- Trial name
- NCT04954833
- Testing
- EMO-200, EMO-118
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Asthenopia, Myopia
The Impact of Soft Contact Lens Attributes on Symptoms Associated With Digital Eye Strain in Symptomatic Soft Contact Lens Wearers
Despite its prevalence, the ocular causes of eye fatigue or unknown and may be related to the cornea/contact lens surface, the accommodative system, the convergence system, overall postural/muscle fatigue, or a combination of…
- Trial name
- NCT03585790
- Testing
- Contact lens with Multifocal Optics, Contact lens with Single Vision Optics
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Pete Kollbaum, OD, PhD
Myopia, Astigmatism
Safety and Efficacy Evaluation of a New Contact Lens Disinfecting Solution in Soft Contact Lens Wearers
The purpose of this study is demonstrate substantial equivalence of an investigational contact lens disinfecting solution to a commercially available contact lens solution in silicone hydrogel and soft contact lens wearers.
- Conditions
- Myopia, Astigmatism, Hyperopia, Refractive Error
- Trial name
- NCT01912768
- Testing
- FID 120947A contact lens disinfecting solution, renu fresh multi-purpose solution, Soft contact lenses
- Volunteers
- 362 people
- Sponsor
- Alcon Research
Ametropia
Endothelial Bleb Response With Toric Lenses
Evaluate the short-term corneal response of oxygen deprivation when using toric contact lenses. The response will be noted by endothelial bleb formation in both open eye and closed eye state.
- Trial name
- NCT00630305
- Testing
- alphafilcon A toric, lotrafilcon B toric, senofilcon A toric
- Where
- Australia
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Astigmatism
Product Performance of a Toric Contact Lens
Product performance of a Bausch \& Lomb Toric Contact Lens compared to Ciba Vision Focus Daily Toric Contact Lens
- Trial name
- NCT00658996
- Testing
- SofLens DD Toric, Ciba Vision Focus Dailies Toric Contact Lens
- Where
- Malaysia
- Volunteers
- 220 people
- Sponsor
- Bausch & Lomb Incorporated
Contact Lens Related Dry Eye
Clinical Evaluation of the Causes of Contact Lens Related Dry Eye
The purpose of this study was to clinically evaluate the potential causes of contact lens-related dry eye.
- Trial name
- NCT00995189
- Testing
- Opti-Free RepleniSH, ReNu MultiPlus, Contact lenses
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- Alcon Research
Astigmatism Bilateral
Evaluation of Wear Experience With a Weekly Replacement Soft Contact Lens in Neophyte Lens Wearers With Astigmatism
This open-label study is of adults with astigmatism who have never worn contact lenses. Subjects will be fit into a one week planned-replacement contact lenses and will wear lenses for approximately 3 weeks.
- Trial name
- NCT06751225
- Testing
- One week replacement soft contact lenses
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ohio State University