Clinical trials: Soft Tissue
Ewing's Sarcoma, Soft Tissue Sarcoma
Tandem Peripheral Blood Stem Cell (PBSC) Rescue for High Risk Solid Tumors
This study uses a double autologous peripheral blood stem cell rescue (PBSC) following dose-intensive chemotherapy for the treatment of high-risk pediatric solid tumors.
- Conditions
- Ewing's Sarcoma, Soft Tissue Sarcoma, Hepatoblastoma, Hodgkin's Disease
- Trial name
- NCT00179816
- Testing
- High-Dose Chemotherapy with Tandem PBSC Rescue.
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Soft Tissue Infections
Phase 2 Safety and Efficacy Study of Daptomycin in Complicated Skin and Skin Structure Infections
multicenter, randomized (1:1), semi-single blind study comparing the safety and efficacy of HDSD daptomycin (10 mg/kg q24h for 4 days) with that of comparator (vancomycin +/- SSP for 7-14 days) in patients with cSSSI due to…
- Trial name
- NCT00426933
- Testing
- Daptomycin, Vancomycin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Sarcoma, Soft Tissue
BAY-43-9006 in Advanced, Metastatic Soft Tissue Sarcomas
The aim of this study (*) is to evaluate the progression free survival rate at 6 months, response rate, overall disease control rate, overall survival of BAY-43-9006 in soft tissue sarcoma patients.
- Trial name
- NCT00406601
- Testing
- Sorafenib (BAY-43-9006)
- Where
- Italy
- Volunteers
- 69 people
- Sponsor
- Istituto Clinico Humanitas
Acute Pain, Soft Tissue Injury
Diclofenac Patch for Treatment of Acute Pain Due to Mild to Moderate Soft Tissue Injuries (TAPED)
The primary purpose of this study is to assess the effectiveness of once daily application of a diclofenac sodium topical patch in reducing mild to moderate soft tissue injuries when applied to the painful area.
- Trial name
- NCT00931866
- Testing
- Diclofenac Sodium
- Where
- United States
- Volunteers
- 407 people
- Sponsor
- Cerimon Pharmaceuticals
Ovarian, Melanoma
Safety and Immune Response to a Multi-component Immune Based Therapy (MKC1106-PP) for Patients With Advanced Cancer.
The present clinical trial is a dose comparison of a multi-component active immunotherapy designed to stimulate an immune reaction to specific tumor associated antigens which are highly expressed on a large number of solid…
- Conditions
- Ovarian, Melanoma, Renal, Prostate
- Trial name
- NCT00423254
- Testing
- PSMA/PRAME
- Where
- 5 sites in United States
- Volunteers
- 12 people
- Sponsor
- Mannkind Corporation
Soft Tissue Defect
Clinical Experience With a Tensor Fasciae Latae Perforator Flap Based on Septocutaneous Perforators
The purpose of this study is to evaluate the possible harvest of a tensor fasciae latae flap based on septocutaneous perforators.This study should further confirm our data from an anatomical study concerning location…
- Trial name
- NCT01136044
- Testing
- septocutaneous perforator flap
- Where
- Austria
- Volunteers
- 14 people
- Sponsor
- Medical University of Graz
Achilles Tendon Rupture, Soft Tissue Injury
Measurement of Mechanical Properties of the Healing Achilles Tendon With or Without Early Weightbearing
The purpose of this study is to measure the mechanical properties of healing Achilles tendons in humans after early controlled weightbearing, compared with a control group in a randomized, single-blinded trial.
- Conditions
- Achilles Tendon Rupture, Soft Tissue Injury, Tendon Injury
- Trial name
- NCT01063465
- Testing
- Early weightbearing
- Where
- Sweden
- Volunteers
- 35 people
- Sponsor
- Linkoeping University
Sarcoma, Soft Tissue
TLC D-99 and Ifosfamide in Metastatic Soft Tissue Sarcoma Patients
The purpose of this study is to determine the maximum tolerated dose of the TLC D-99 combined with ifosfamide and then the efficacy of this combination in terms of overall response rate, time to progression and time of response
- Trial name
- NCT00289809
- Testing
- combination of TLC D-99 and Ifosfamide
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Istituto Clinico Humanitas
Neuroblastoma, Ewings Sarcoma
Intensive Chemo-Radiotherapy With Peripheral Blood Progenitor Cell Rescue for Children With Advanced Neuroblastoma and Sarcomas
The main purpose of this study is to determine the short and long term side effects of a very intensive treatment, which includes combinations of chemotherapy drugs followed by radiation therapy and two transplants supported by…
- Conditions
- Neuroblastoma, Ewings Sarcoma, Non-rhabdomyosarcoma Soft Tissue Sarcoma
- Trial name
- NCT00165139
- Testing
- Vincristine, Cyclophosphamide, Adriamycin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dana-Farber Cancer Institute
Ewing, Soft Tissue Sarcoma
Hematopoietic Stem Cell Transplantation From Human Leukocyte Antigen (HLA) Compatible Donor in Ewing Sarcomas and Soft Tissues Sarcomas
This is a perspective multicentric study for the treatment of patients aged equal or less than 60 years and submitted to an allogeneic hematopoietic stem cell transplantation from an HLA compatible related or unrelated donor…
- Trial name
- NCT00998361
- Testing
- Allogeneic hemopoietic stem cell transplant
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Skin and Soft Tissue Infections, Methicillin-resistant Staphylococcus Aureus
Safety and Pharmacokinetics of Ascending Single Oral Doses of EDP-322 in Nonfasting and Fasting Healthy Volunteers
This was a randomized, double-blind, placebo-controlled, ascending single dose safety, tolerability, and pharmacokinetic study of orally administered EDP-322. This study was conducted at a single site.
- Trial name
- NCT00989872
- Testing
- EDP-322
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Enanta Pharmaceuticals, Inc
Sarcoma, Soft Tissue
a Multicenter Clinical Trial for the Treatment of Children and Adolescents With Soft Tissue Sarcoma Stage 4
Phase II Study to evaluate the response on two blocks of topotecan and carboplatin
- Trial name
- NCT00130858
- Testing
- Topotecan, Carboplatin
- Where
- 38 sites in Germany
- Volunteers
- 90 people
- Sponsor
- Cooperative Weichteilsarkom Study Group
Joint Pain, Musculoskeletal Pain
IDEA-033 Open Label Study
The main aim of the study is to evaluate safety, efficacy, compliance, and usage of epicutaneously applied IDEA-033 in joint / musculoskeletal pain or soft tissue inflammation.
- Conditions
- Joint Pain, Musculoskeletal Pain, Stiffness, Soft Tissue Inflammation in Designated Target Area(s)
- Trial name
- NCT00372333
- Testing
- IDEA-033
- Where
- Germany
- Volunteers
- 491 people
- Sponsor
- IDEA AG
Infection
Unnecessary IV Antibiotic Days Using General Criteria for Antibiotic Switch
Observation of the use of intravenous antibiotics in medical clinic of Sorlandet Hospital, Norway. Suggestions of criteria for the switch from intravenous to oral administration of antibiotics.
- Trial name
- NCT00763373
- Testing
- Implementation of antibiotic switch guidelines
- Where
- 2 sites in Norway
- Volunteers
- 187 people
- Sponsor
- Sorlandet Hospital HF
Soft Tissue Sarcomas, Thyroid Cancer
11C-Acetate PET/CT Non-FDG-Avid Tumors
F18-FDG is the widely used PET tracer in the routine practice of oncologic disease imaging using the technology of PET-CT. However, FDG-avidity is a characteristic of the individual tumor.
- Conditions
- Soft Tissue Sarcomas, Thyroid Cancer, Lung Cancer, Indolent Lymphoma
- Trial name
- NCT00687778
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Soft Tissue Sarcoma
Phase I-II Trial of Sorafenib in Combination With Ifosfamide in Soft Tissue Sarcoma
Soft tissue sarcomas (STS) are an uncommon group of malignant tumors of mesenchymal origin. For most advanced STS types, chemotherapy is currently the only available treatment.
- Trial name
- NCT00541840
- Testing
- Sorafenib
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- Grupo Espanol de Investigacion en Sarcomas
Trauma Patients With Soft Tissue Defects
Are the Pancreatic Serum Proteins Pancreatic Stone Protein (PSP) and Pancreatitis-Associated Protein (PAP) Predictive for the Development of Sepsis? Retrospective Study in Trauma Patients With Soft Tissue Defects.
Retrospective analysis of PSP- and PAP-serum levels in trauma patients with soft tissue defects and possible correlation with the incidence and onset of infection and sepsis.
- Trial name
- NCT00564109
- Testing
- retrospective Observation
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- University of Zurich
Soft Tissue Neoplasms
Radiofrequency Ablation of Painful Soft Tissue Neoplasms
Radiofrequency ablation is used to treat patients with many different conditions. It is used to treat heart arrhythmia and benign bone tumors, and to control bleeding during surgery.
- Trial name
- NCT00041886
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Sarcoma, Soft Tissue
Study of Gemcitabine and Vinorelbine in Soft Tissue Sarcomas
The purpose of this study is to determine if the combination of gemcitabine and vinorelbine is effective in treating patients with advanced soft tissue sarcoma.
- Trial name
- NCT00134641
- Testing
- gemcitabine, vinorelbine
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Dana-Farber Cancer Institute
Sarcoma, Soft Tissue
Study Evaluating the Safety and Efficacy of ABT-510 in Subjects With Locally Advanced or Metastatic Soft Tissue Sarcoma
The primary objective of this study is to assess the safety and effectiveness of ABT-510 in subjects with locally advanced or metastatic soft tissue sarcoma.
- Trial name
- NCT00061659
- Testing
- ABT-510 - Thrombospondin-1 mimetic
- Where
- 5 sites in United States
- Volunteers
- 88 people
- Sponsor
- Abbott