Clinical trials: Soft Tissue Atrophy
Soft Tissue Atrophy
Effectiveness of Xenogenic Collagen Matrix in Modification of Mucosal Phenotype Around Dental Implants
Aim of the study The rationale for conducting the present study is to evaluate the efficacy of porcine collagen matrix in the management of defective width of keratinized mucosa around dental implant.
- Trial name
- NCT07577193
- Testing
- All dental implants will be placed in edentulous the area with application of free gingival graft (Group I) or with incorporation of porcine collagen matrix (Group II).
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University
Dehiscence, Alveolar Ridge Enlargement
Implant-supported Rehabilitation With SPAL Technique or Soft Tissue Augmentation
The primary aim of the present study is to compare the Sub-periosteal Peri-implant Augmented Layer (SPAL) technique and soft tissue augmentation (STA), performed simultaneously to implant placement, in terms of (i) implant…
- Conditions
- Dehiscence, Alveolar Ridge Enlargement, Bone Loss, Alveolar
- Trial name
- SPALvsSTA (NCT05610748)
- Testing
- Sub-Periosteal Peri-implant Augmented Layer technique, Soft tissue augmentation
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- Università degli Studi di Ferrara
Volume Loss (Soft Tissue Ptosis or Atrophy )
Pan Facial Volume Restoration
The aim of this study is to assess performance and tolerance as well as investigator and subject satisfaction further to pan-facial volume restoration with a new cross-linked hyaluronic acid dermal filler containing lidocaine…
- Trial name
- EVE (NCT01545557)
- Testing
- Hyaluronic acid dermal filler gel
- Where
- 3 sites in Brazil
- Volunteers
- 60 people
- Sponsor
- Galderma R&D
Soft Tissue Atrophy
Comparative Analysis Using the Collagen Matrix and Autogenous Graft: Clinical Course, Aesthetic Results
This was an interventional prospective randomized clinical trial (RCT) in parallel groups. The sample size is 32 patients who were randomly divided into two groups depending on the surgical intervention used.
- Trial name
- NCT05870774
- Testing
- Soft tissue augmentation with CTG, Soft tissue augmentation with CM
- Where
- Russia
- Volunteers
- 52 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Zygomatic Implants, Atrophic Maxilla
Buccal Fat Pad vs. Palatal Rotation Scarf Grafts for Soft Tissue Management Around Zygomatic Implants
Over the past 20 years, the demand for oral rehabilitation among edentulous patients has steadily increased. Traditionally, individuals with edentulous maxillae were treated using removable complete dentures.
- Conditions
- Zygomatic Implants, Atrophic Maxilla, Soft Tissue Defect, Soft Tissue Healing
- Trial name
- RCT BFP ZAGA (NCT06968780)
- Testing
- Buccal Fat Pad, Palatal Rotation Scarf Graft
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Cairo University
Soft Tissue Atrophy
Peri-Implant Soft Tissue Augmentation Using a Free Connective Tissue Graft With an Epithelial Collar
A prospective randomized interventional clinical trial (RCT) with a parallel-group design is planned. The study sample will include 32 patients randomly allocated into two groups according to the surgical intervention performed.
- Trial name
- NCT07626866
- Testing
- Free connective tissue graft without an epithelial collar, Free connective tissue graft with epithelial collar
- Where
- Russia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Gingival Atrophy
Soft Tissue Augmentation Around Dental Implant
Patients were randomly distributed into two groups (G1 and G2), all patients were treated by a submerged dental implant protocol and free gingival graft (FGG) harvested from the palate as follows: Group 1 (G1), received the FGG…
- Trial name
- NCT06238427
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Tooth Socket, Dental Implants
Impact of Soft Tissue Grafts on Tissue Alterations After Immediate Tooth Replacement
This study evaluates the impact of soft tissue grafts on soft tissue recession following immediate implant, provisional and bone graft placement in compromised sockets.
- Trial name
- NCT02922075
- Testing
- Connective tissue graft, Collagen matrix graft, Immediate implant
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- São Paulo State University
Soft Tissue Atrophy
Clinical and Histological Outcomes of Using Collagen Matrix or Soft Tissue Graft Around Implants
This was an interventional prospective randomized clinical trial (RCT) in parallel groups. The sample size is 35 patients who were randomly divided into two groups depending on the surgical intervention used.
- Trial name
- NCT05123898
- Testing
- Soft tissue augmentation
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Cleft Lip and Palate, Periodontal Pocket
Periodontal Changes Following Mid Maxillary Distraction
To evaluate the health status of the periodontium and dentition at the distraction osteogenesis site in CLP subjects using mid maxillary distraction (MMD).
- Conditions
- Cleft Lip and Palate, Periodontal Pocket, Attachment Loss, Periodontal
- Trial name
- NCT03686761
- Testing
- A Involvement with the osteotomy site of the surgery
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alexandria
Immediate Implants, Alveolar Bone Loss
Evaluation of Immediate Implant Placement In The Esthetic Zone Using the Bone Shielding Concept Versus Dual Zone Therapy
Immediate implant placement has proven to be a successful treatment procedure that is preferred by patients because of being less traumatic, more time-efficient.
- Conditions
- Immediate Implants, Alveolar Bone Loss, Dual Zone Technique, the Bone Shielding Concept
- Trial name
- NCT05381467
- Testing
- immediate implant placement with The Dual-Zone Therapeutic Concept, Immediate implant placement with the bone shielding concept
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Loss, Sinus Pneumatization
Microarchitecture of the Augmented Bone Following Sinus Elevation
In this prospective randomized clinical study sinus floor elevation procedures are preformed using different biomaterials with the lateral window technique.
- Conditions
- Alveolar Bone Loss, Sinus Pneumatization, Edentulous; Alveolar Process, Atrophy
- Trial name
- MAB (NCT04136509)
- Testing
- sinus floor elevation, bone core biopsy, dental implant placement
- Where
- Hungary
- Volunteers
- 40 people
- Sponsor
- Semmelweis University
Alveolar Bone Loss, Tooth Loss
Changes of Soft and Hard Tissues After Alveolar Ridge Preservation: Freeze-dried Bone Allograft vs. L-PRF Clot
A Clinical Trial to study the effectiveness between two, tooth socket grafting materials namely, Freeze Dried Bone Allograft (human derived bone particles) and Leukocytic-Platelet Rich Fibrin (the patient's own centrifuged…
- Trial name
- NCT03331185
- Testing
- Freeze Dried Bone Allograft, L-PRF clot
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Soft Tissue Atrophy
Increasing the Thickness of Soft Tissues in the Esthetic Zone Around Implants
This is an interventional prospective randomized clinical trial (RCT) in parallel groups. This study is aimed at detecting a difference in the increase in the thickness of soft tissues of at least 0.3 mm between the two groups…
- Trial name
- NCT05551962
- Testing
- Soft tissue augmentation with CTG, Soft tissue augmentation with CM
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Gingival Recession
Amnion Membrane Versus DFGG Using the Tunneling Technique in Management of Gingival Recession Defects.
Treatment of gingival recession is indicated mainly for esthetic reasons and keratinized tissue augmentation (Zucchelli and Mounssif, 2015).
- Trial name
- NCT06146855
- Testing
- Tunneling procedure with Amnion Membrane, Tunneling procedure with De-epithelialized Free Gingival Graft
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession
Root Biomodification With Citric Acid and Tetracycline Improves the Outcomes of Root Coverage
The aim of this study is to investigate the effects of the application of a citric acid + tetracycline gel solution during 90 or 180 seconds compared to no conditioning in the outcomes of treatment of Miller's class I or II…
- Trial name
- NCT02259543
- Testing
- Root conditioning with citric acid+tetracycline solution
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Bone Loss, Alveolar, Dental Implant Failed
Clinical and Radiographic Evaluation of Bone and Tissue Level Single Unit Implants: Two-piece Abutment Concept
Dental implants have become one of the most common treatments used for the rehabilitation of lost teeth. The success rate of dental implant treatment is quite high.
- Trial name
- NCT05592821
- Testing
- dental implant placement
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Berceste Guler
Recession, Gingival, Bone Loss in Jaw
L-PRF vs Connective Tissue With Customized Healing Abutment in Immediate Implant Placement
comparison between L-prf and connective tissue with dental implant
- Trial name
- NCT07102758
- Testing
- L-PRF with dental implant and customized healing abutment, Connective tissue with dental implant and customized healing abutment
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Atrophic Edentulous Maxilla, Zygomatic Implants
Assessment of Soft Tissue Thickness Over Zygomatic Implants in Atrophied Maxilla Covered With Buccal Fat Pad vs. Palatal Pedicle Flap
Background and Rationale The rehabilitation of the severely atrophied maxilla utilizing zygomatic implants is a highly predictable and effective treatment modality.
- Conditions
- Atrophic Edentulous Maxilla, Zygomatic Implants, Dental Implant, Soft Tissue Augmentation at Dental Implants
- Trial name
- NCT07574606
- Testing
- Palatal pedicle over zygomatic implant, covering zygomatic implants using buccal fat pad
- Where
- Egypt
- Volunteers
- 4 people
- Sponsor
- Future University in Egypt
Atrophy of Breast
Efficacy and Safety Study of EVERA to Augment Small Breast
Expected Total Number of Subjects Level of significance, alfa 0.05 Power 0.80 Mean difference between two treatments is assumed 35 Standard Deviation is assumed 35. Follow-up loss is assumed 20% N=34(each group:17)
- Trial name
- NCT02009137
- Testing
- EVERA, ESTES
- Where
- South Korea
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital