Clinical trials: Soft Tissue Atrophy
Gingival Recession
A New Therapeutic Approach for Root Coverage
Different surgical techniques have been proposed for root coverage, showing varying results especially in areas of deep recessions.
- Trial name
- NCT01143610
- Testing
- Newly forming bone technique for root coverage, Subepithelial connective tissue graft for root coverage.
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Alveolar Bone Loss
Influence of Thickness of the Peri-implant Soft Tissue on Marginal Bone Remodeling
The aim of this observational study is the evaluation of marginal bone remodeling after surgical implant placement, correlating the gingival thickness with the bone resorption rate.
- Trial name
- STR (NCT03077880)
- Testing
- intra-operatory measurement during implant placement
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- International Piezosurgery Academy
Alveolar Bone Loss
Autologous Fat Grafting Versus Subepithelial Connective Tissue Graft for Volume Augmentation
The aim of this study was to evaluate the effectiveness of autologous fat as a grafting material for soft tissue volume augmentation of localized horizontal ridge defects in humans.
- Trial name
- NCT04214041
- Testing
- Autologous fat grafting, Sub-epithelial connective tissue graft
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Nourhan M.Aly
Zygomatic Implants, Atrophic Maxilla
Buccal Fat Pad vs. Palatal Rotation Scarf Grafts for Soft Tissue Management Around Zygomatic Implants
Over the past 20 years, the demand for oral rehabilitation among edentulous patients has steadily increased. Traditionally, individuals with edentulous maxillae were treated using removable complete dentures.
- Conditions
- Zygomatic Implants, Atrophic Maxilla, Soft Tissue Defect, Soft Tissue Healing
- Trial name
- RCT BFP ZAGA (NCT06968780)
- Testing
- Buccal Fat Pad, Palatal Rotation Scarf Graft
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Cairo University
Recession, Gingival
Palatal Volumetric Change Analysis Following Connective Tissue Graft With and Without Donor Site Augmentation
The goal of this randomized clinical trial is to compare whether soft tissue augmentation placed in the donor site following a gum graft harvesting leads to volumetric changes compared to non-augmented sites in the palate.
- Trial name
- NCT05961566
- Testing
- Use of collagen matrix after subepithelial connective tissue graft harvest
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hailey Bivens
Gingival Recessions
Guided Versus Non-Guided Harvesting Technique of Soft Tissue Graft in Cairo Recession Type I Sites
The goal of this clinical trial is to compare the healing pattern in the palate following harvesting of deepithelialized free gingival graft by two different harvesting techniques and to compare the recession coverage at the…
- Trial name
- RCT (NCT06603467)
- Testing
- non-guided de-epithelialized free gingival graft harvested, guided de-epithelialized free gingival graft harvested
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Tanta University
Gingival Recession
To Compare Two Commonly Used Soft Tissue Grafting Techniques to Achieve Coronal Flap Advancement and Root Coverage
This study will compare two incision designs to allow for coronal gingival/mucosal flap advancement and tissue augmentation with acellular dermal matrix (ADM) graft around teeth with gingival recession and a lack of adequate…
- Trial name
- VISTA (NCT03566108)
- Testing
- VISTA, STA
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Gingival Recession
Expression of Angiogenic Biomarkers During Healing of Intra-Oral Soft Tissue Engineered Grafts
The purpose of this observational research study is to understand more about wound healing of gum tissue. This study was the biomarker study of a small cohort of study participants derived from NCT01547962 (completed).
- Trial name
- NCT01134081
- Testing
- CelTx™, Free Gingival Graft
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Michigan
Immediate Implants, Alveolar Bone Loss
Evaluation of Immediate Implant Placement In The Esthetic Zone Using the Bone Shielding Concept Versus Dual Zone Therapy
Immediate implant placement has proven to be a successful treatment procedure that is preferred by patients because of being less traumatic, more time-efficient.
- Conditions
- Immediate Implants, Alveolar Bone Loss, Dual Zone Technique, the Bone Shielding Concept
- Trial name
- NCT05381467
- Testing
- immediate implant placement with The Dual-Zone Therapeutic Concept, Immediate implant placement with the bone shielding concept
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Soft Tissue Atrophy
Peri-Implant Soft Tissue Augmentation Using a Free Connective Tissue Graft With an Epithelial Collar
A prospective randomized interventional clinical trial (RCT) with a parallel-group design is planned. The study sample will include 32 patients randomly allocated into two groups according to the surgical intervention performed.
- Trial name
- NCT07626866
- Testing
- Free connective tissue graft without an epithelial collar, Free connective tissue graft with epithelial collar
- Where
- Russia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Gingival Recession Generalized Moderate, Gingival Recession Localized Moderate
Comparing CAF and TCAF With Soft Tissue Grafting for Treating Multiple Recessions in the Maxilla.
Multiple techniques can be used for recession coverage. The most common techniques are: tunnel technique (T), coronally advanced flap (CAF) or a combination of both (TCAF).
- Conditions
- Gingival Recession Generalized Moderate, Gingival Recession Localized Moderate, Gingival Recession, Generalized, Gingival Recession, Localized
- Trial name
- NCT07158528
- Testing
- coronally advanced flap with connective tissue graft, tunneled coronally advanced flap with a connective tissue graft
- Where
- Belgium
- Volunteers
- 34 people
- Sponsor
- University Hospital, Ghent
Soft Tissue Atrophy
Clinical and Histological Outcomes of Using Collagen Matrix or Soft Tissue Graft Around Implants
This was an interventional prospective randomized clinical trial (RCT) in parallel groups. The sample size is 35 patients who were randomly divided into two groups depending on the surgical intervention used.
- Trial name
- NCT05123898
- Testing
- Soft tissue augmentation
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Gingival Recession, Localized, Soft Tissue Volume Changes
3D Digital Assessment of Soft Tissue Changes After Modified FGG
The aim of this randomized controlled clinical trial is to evaluate the effects of conventional free gingival graft (FGG) and modified free gingival graft (ModFGG) techniques on soft tissue thickness, volumetric change, and…
- Conditions
- Gingival Recession, Localized, Soft Tissue Volume Changes, Keratinized Tissue Deficiency
- Trial name
- NCT07409558
- Testing
- Modified Free Gingival Graft (ModFGG), Conventional Free Gingival Graft (FGG)
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Atrophy of Breast
Efficacy and Safety Study of EVERA to Augment Small Breast
Expected Total Number of Subjects Level of significance, alfa 0.05 Power 0.80 Mean difference between two treatments is assumed 35 Standard Deviation is assumed 35. Follow-up loss is assumed 20% N=34(each group:17)
- Trial name
- NCT02009137
- Testing
- EVERA, ESTES
- Where
- South Korea
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Alveolar Bone Loss
Soft Tissue Width and Abutment Height Influence Peri-implant Bone Resorption
The purpose of this clinical and radiographic study will be to determine what influence on marginal bone loss has the thickness of soft tissues and the height of the prosthetic abutment and eventually determine which of the two…
- Trial name
- i-RES (NCT03229005)
- Testing
- implant insertion, operculectomy, prosthetic rehabilitation
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Gingival Recession, Generalized, Graft Reaction
The Healing of Soft Tissue Augmentation by Acellular Dermal Matrix and Autogenous Subepithelial Connective Tissue Graft
The study team proposes to prospectively compare the healing outcomes of autogenous soft tissue connective tissue graft (CTG) and Acellular dermis matrix (ADM) in a split-mouth design study for patients requiring modification of…
- Trial name
- NCT03954028
- Testing
- Gingival Punch Biopsy after healing of Gingival Soft Tissue Augmentation
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Soft Tissue Atrophy
Effectiveness of Xenogenic Collagen Matrix in Modification of Mucosal Phenotype Around Dental Implants
Aim of the study The rationale for conducting the present study is to evaluate the efficacy of porcine collagen matrix in the management of defective width of keratinized mucosa around dental implant.
- Trial name
- NCT07577193
- Testing
- All dental implants will be placed in edentulous the area with application of free gingival graft (Group I) or with incorporation of porcine collagen matrix (Group II).
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University
Soft Tissue Atrophy
Cyanoacrylate With Sutures for Fixation of Free Gingival Graft
fixation of FGG with sutures alone is not sufficient,we use cyanoacrylate beside sutures for fixation
- Trial name
- NCT04063475
- Testing
- cyanoacrylate tissue adhesive beside sutures
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession
Changes in Soft Tissue Thickness Following Multiple Coronally Advanced Tunnel (MCAT) vs Vestibular Incision Subperiosteal Tunnel Access (VISTA)
This randomized clinical trial will compare two surgical methods for treating multiple adjacent gingival recessions (types RT1 and RT2): the Modified Coronally Advanced Tunnel (MCAT) and the Vestibular Incision Subperiosteal…
- Trial name
- NCT07200258
- Testing
- Vestibular Incision Subperiosteal Tunnel Access (VISTA), Modified Coronally Advanced Tunnel (MCAT)
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Universidad Complutense de Madrid