Clinical trials: Soft Tissue Augmentation, open to volunteers
Thin Peri-implant Mucosal Phenotype
Peri-implant Soft Tissue Augmentation Using Microneedling With i-PRF vs. Connective Tissue Graft
This randomized controlled clinical trial aims to evaluate a minimally invasive technique for peri-implant soft tissue augmentation using microneedling combined with injectable platelet-rich fibrin (i-PRF) compared with the…
- Trial name
- NCT07667855
- Testing
- Connective Tissue Graft (CTG), Microneedling with Injectable Platelet-Rich Fibrin (MN+i-PRF)
- Where
- Lebanon
- Volunteers
- 24 people
- Sponsor
- Beirut Arab University
Alveolar Ridge Augmentation, Bone Substitutes
Alveolar Ridge Preservation (ARP) Study Using Alloplastic Biomaterial and a Resorbable Synthetic Membrane. A Digital Workflow (CBCT/Scanner) Evaluates Hard and Soft Tissue Volumetric Changes at 4 Months, Validating Support for the Gingival Phenotype and Buccal Bone Plate.
The dimensional collapse of the alveolar ridge following tooth extraction represents a critical challenge for implant rehabilitation.
- Conditions
- Alveolar Ridge Augmentation, Bone Substitutes, Guided Tissue Regeneration, Periodontal, Cone-Beam Computed Tomography
- Trial name
- NCT07879495
- Testing
- Alveolar Ridge Preservation using a synthetic alloplastic bone substitute and a resorbable polymer membrane, Minimally invasive flapless tooth extraction followed by unassisted spontaneous healing
- Volunteers
- 28 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Free Gingival Graft, Soft Tissue Augmentation Around Dental Implants
Clinical Evaluation of a Modified Technique for Free Gingival Graft Stabilization Using Titanium Fixation Tacs Around Implants Versus Conventional Suturing Technique
The aim of this randomized, controlled, parallel-grouped, clinical trial is to evaluate the width of keratinized gingiva after free gingival graft stabilized by titanium fixation tacs compared to traditional suturing.
- Conditions
- Free Gingival Graft, Soft Tissue Augmentation Around Dental Implants, Inadequate Keratinized Tissue Around Dental Implants
- Trial name
- NCT07019428
- Testing
- Free gingival graft stabilized by Titanium fixation tacs, Free gingival graft stabilized by sutures
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Soft Tissue Augmentation
The Use of a Porcine Collagen Matrix for the Prevention of Buccal Bone Wall Resorption During Implant Placement in the Aesthetic Zone.
Aim: To provide a comparative assessment of the clinical and radiographic effect of porcine collagen matrix when placed buccally at the time of single implant placement in the aesthetic zone vs autogenous connective tissue graft…
- Trial name
- NCT06622759
- Testing
- CTG, Collagen Matrix, Control group
- Where
- Greece
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Thin Gingival Biotype
Efficacy of Microneedling With Hyaluronic Acid Injection for Gingival Augmentation in Thin Gingival Phenotype
This randomized controlled trial adheres to the Consolidated Standards of Reporting Trials (CONSORT) 2010 guidelines and the Declaration of Helsinki ethical principles for medical research.
- Trial name
- NCT07317856
- Testing
- Microneedling (MN), Microneedling + Injectable Hyaluronic Acid (MN + HA)
- Where
- Iraq
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Dental Implantation, Peri-Implant Soft Tissue Deficiency
Volume-Stable Collagen Matrix vs. Connective Tissue Graft for Peri-Implant Soft Tissue Defects
Peri-implant soft-tissue defects will be treated with either a volume-stable collagen matrix (VCMX; test group) or an autogenous connective tissue graft (CTG; control group) following implant placement in patients with a single…
- Conditions
- Dental Implantation, Peri-Implant Soft Tissue Deficiency, Soft Tissue Augmentation
- Trial name
- NCT07782125
- Testing
- Connective tissue graft, Volume-stable collagen matrix
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ankara University
Dental Crowding, Gingival Recession
Evaluating the Clinical Efficacy of Collagen Scaffold (Ossix VOLUMAX) With Piezo-Surgical Decortication in Enhancing Orthodontic Treatment Outcomes: A Randomized Controlled Trial
Recent advances in orthodontic treatment have explored various materials to enhance treatment efficacy, particularly focusing on collagen scaffolds.
- Conditions
- Dental Crowding, Gingival Recession, Thin Phenotype
- Trial name
- NCT07097714
- Testing
- Piezocision with ribose cross-linked collagen matrix (Ossix® Volumax), control
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- NMSI DENTMASTER
Implant Complication
Vertical Soft Tissue Augmentation With CTG vs ADM
The study aims at comparing two different approaches for vertical soft tissue augmentation at implant sites exhibiting soft tissue dehiscences: autogenous connective tissue graft vs acellular dermal matrix + enamel matrix…
- Trial name
- NCT05729607
- Testing
- Vertical soft tissue augmentation
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Recession, Gingival, Bone Loss in Jaw
L-PRF vs Connective Tissue With Customized Healing Abutment in Immediate Implant Placement
comparison between L-prf and connective tissue with dental implant
- Trial name
- NCT07102758
- Testing
- L-PRF with dental implant and customized healing abutment, Connective tissue with dental implant and customized healing abutment
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Soft Tissue Augmentation Around Dental Implants
Porcine Derma for Soft Tissue Augmentation Around Implants
Brief description of the study objectives The present study aims to evaluate the effectiveness of the porcine-derived collagen matrix Derma OsteoBiol® for peri-implant soft tissue augmentation.
- Trial name
- CT (NCT07436091)
- Testing
- Soft tissue augmentation with Derma OsteoBiol® around dental implants.
- Where
- Portugal
- Volunteers
- 15 people
- Sponsor
- Universidade do Porto
Soft Tissue Augmentation, Gingival Recession Localized Moderate
Evaluation of the Effect of Smoking on Palatal Donor Site Tissue Profile in the Success of Connective Tissue Grafts
This single-center prospective clinical study investigates how smoking affects palatal donor site tissue biology and, in turn, the success of connective tissue grafts used in root coverage surgery.
- Conditions
- Soft Tissue Augmentation, Gingival Recession Localized Moderate, Palatal Morphology
- Trial name
- NCT07777185
- Testing
- Coronally Advanced Flap with Subepithelial Connective Tissue Graft (CAF + CTG)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ankara University
Keratinized Tissue Augmentation Around Dental Implants
Keratinized Tissue Augmentation Using Augmented Gingival Matrix Compared to Free Gingival Graft Around Implants
This is a 12-month, randomized, examiner-blinded, controlled, two-arm, parallel-group, single-site clinical trial comparing a biocompatible tissue graft (Augmented Gingival Matrix barrier) with a free gingival graft (FGG) to…
- Trial name
- NCT07863882
- Testing
- Augmented Gingival Matrix graft, Free Gingival Graft
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Forsyth Institute
Aesthetic Body Volume Loss
Efficacy and Safety of BtH Body 2.2% (Injectable Hyaluronic Acid) in Volumizing and Contouring Large Areas of the Body: Prospective Clinical Investigation.
This clinical investigation is a prospective, interventional, single-center study designed to assess the safety and effectiveness of BtH Body 2.2%, a cross-linked hyaluronic acid injectable intended for aesthetic volumization and…
- Trial name
- NCT07441135
- Testing
- BtH Body 2.2%
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- i+Med S.Coop.
Keratinized Mucosa, Keratinized Tissue
Efficacy of Collagen Matrix for Peri-implant Soft Tissue Phenotype Modification
A stable band of keratinized mucosa (KM) around dental implants is thought to minimize tissue recession and provide resistance against mechanical, chemical, and microbial challenges, thereby preserving peri-implant tissue health.
- Trial name
- XCM versus FGG (NCT07056959)
- Testing
- Soft tissue substitute for peri-implant phenotype modification, Control Group - Free gingival graft for soft tissue augmentation
- Where
- United Arab Emirates
- Volunteers
- 30 people
- Sponsor
- Mohammed Bin Rashid University of Medicine and Health Sciences
Peri-implant Soft Tissue Deficiency, Partial Edentulism
Soft Tissue Augmentation Around Dental Implants Using Connective Tissue Graft, Submerged Tenting Abutment, or Sub-crestal Implant Placement
Peri-implant soft tissue thickness is an important determinant of the long-term stability and success of dental implants. Patients with a thin peri-implant soft tissue phenotype are at increased risk of soft tissue recession…
- Conditions
- Peri-implant Soft Tissue Deficiency, Partial Edentulism, Tooth Loss
- Trial name
- NCT07714265
- Testing
- subepithelial connective tissue graft, Submerged Tenting Abutment, Sub-crestal Implant Placement
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Misr International University
Acellular Dermal Matrix, Bone Grafting
Evaluating the Barrier Function, Regenerative Capacity, and Soft Tissue Outcomes of Acellular Dermal Matrix
This investigator-initiated study will compare ADM and resorbable cross-linked collagen membrane barriers for guided bone regeneration at atrophic lateral ridge augmentation sites.
- Conditions
- Acellular Dermal Matrix, Bone Grafting, Soft Tissue Grafting
- Trial name
- NCT07613047
- Testing
- Guided Bone Regeneration with ADM (AlloDerm) as a barrier, Guided Bone Regeneration with Resorbable Crosslinked Collagen Matrix (Mem-Lok) as a barrier
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Acellular Dermal Matrix, Alveolar Mucosa
Assessment of Two Soft Tissue Augmentation Using Acellular Dermis Around Dental Implants
This study aims to compare soft tissue grafting with acellular dermis at Phase I or Phase II dental implant surgery.
- Trial name
- NCT07512245
- Testing
- Phase I dental implant placement with acellular dermis, Phase II dental implant uncovery with acellular dermis
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Soft Tissue Augmentation Around Dental Implants
Vertical Soft Tissue Augmentation With Tent Pole Technique and Its Influence on Marginal Bone Loss Around Dental Implants
This study aims to evaluate the effectiveness of the tent pole technique in vertical peri-implant soft tissue augmentation and to assess its impact on marginal bone loss.
- Trial name
- NCT07018531
- Testing
- VST augmentation with TPT, TPT-PRF, TPT-PBM
- Where
- 2 sites in Spain, Tunisia
- Volunteers
- 112 people
- Sponsor
- University of Santiago de Compostela
Soft Tissue Augmentation at Dental Implants
Assessment of Soft Tissue Thickness Following Utilization of Buccal Pad of Fat Versus Platelet-rich Fibrin for Covering Zygomatic Implants: A Randomized Clinical Trial
Would buccal pad of fat be comparable to platelet rich fibrin for Zygomatic implant coverage as a step for reconstruction of atrophic posterior maxilla, in terms of peri-implant soft tissue thickness and avoiding complicated…
- Trial name
- NCT07562334
- Testing
- Coverage with PRF for Zygomatic implant placed
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Augmentation, Fibroadenoma
Regional Anesthesia Techniques in Breast Surgery
This clinical trial aims to evaluate the efficacy of liposomal bupivacaine and ropivacaine, when administered via paravertebral block, the rhomboid intercostal and subserratus plane (RISS) block, PECS II block, intercostal nerve…
- Conditions
- Augmentation, Fibroadenoma, Mastectomy
- Trial name
- NCT06779656
- Testing
- General Anesthesia (GA), Paravertebral Block (PVB), Rhomboid Intercostal and Subserratus Plane Block (RISS)
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Xiaguang Duan