Clinical trials: Soilings, Fecal
Fecal Incontinence, Encopresis
Biofeedback Vs Electrical Stimulation in Treatment of Fecal Incontinence
Fecal incontinence is one of the most psychological frustrating problems. It occurs in children due to many causes. There is a wide range of non-invasive therapeutic approaches like Kegel exercise, Biofeedback, and posterior…
- Conditions
- Fecal Incontinence, Encopresis, Fecal Soiling
- Trial name
- NCT04380571
- Testing
- Biofeedback, Electrical stimulation, Traditional treatment
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Cairo University
Anal Incontinence or Constipation
Does Body Position Influence Pressure Recording by High-resolution Manometry ?
The anorectal manometry is the gold standard in the evaluation of anorectal function. Several techniques are currently used (balloons, perfused catheters) and are always performed in the supine position.
- Trial name
- NCT01946334
- Testing
- anorectal manometry and high-resolution three-dimensional
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Faecal Incontinence
Long-term Efficacy of Percutaneous Tibial Nerve Stimulation Applied to Patients With Faecal Incontinence.
Percutaneous tibial nerve stimulation (PTNS) is an ambulatory therapy validated for patients with Faecal Incontinence (FI) refractory to conservative treatment with proved short and mid-term efficacy.
- Trial name
- PTNSLONG (NCT05016453)
- Where
- Spain
- Volunteers
- 139 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Spina Bifida
Retrograde Colonic Irrigation to Manage Spina Bifida Functional Digestive Sequelae: a Multicenter, Prospective, Randomized Controlled Trial
Spina Bifida is a developmental congenital disorder caused by the incomplete closing of the embryonic neural tube, leading to serious malformations of the nervous system.
- Trial name
- IRRICO (NCT02361450)
- Testing
- Retrograde Colonic Irrigation, Usual Care
- Where
- 6 sites in France
- Volunteers
- 34 people
- Sponsor
- Rennes University Hospital
Faecal Incontinence
Safety and Tolerability of the Twice Daily Intra-anal Application of NRL001 Cream for 14 Days
The study is being conducted to evaluate the safety and tolerability after single and repeated twice daily intra-anal applications of 1mL NRL001 cream in stepwise increasing concentrations.
- Trial name
- NCT06593730
- Testing
- NRL001 cream 0.5%w/w, NRL001 cream 0.75%w/w, NRL001 cream 1.0%w/w
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Norgine
Fecal Incontinence
EPIC :Anal Incontinence After Delivery. Secondary Prevention With Caesarean Section.
Anal incontinence is frequent and treatment is difficult. One of the most important reasons is traumatic delivery. 10 % of women develop anal incontinence after first delivery.
- Trial name
- EPIC (NCT00632567)
- Testing
- caesarean section, vaginal delivery
- Where
- France
- Volunteers
- 554 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Total Colectomy, Diarrhea
Defining Ileorectal Syndrome: a Prospective Observational Study
1. Study Title: Trying to Define Ilorectal Syndrome: A Prospective Observational Study 2. Study Objective and Significance: Primary Objective: To prospectively evaluate the frequency, symptom severity, and impact on quality of…
- Conditions
- Total Colectomy, Diarrhea, Urgency Incontinence, Soilings, Fecal
- Trial name
- DEFINE-IRS (NCT07385196)
- Testing
- survey study
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Spinal Cord Injuries, Constipation
Pharmacokinetics of Neostigmine and Glycopyrrolate
A group of 6 able-bodied healthy volunteers will receive Neostigmine (NEO) and Glycopyrrolate (GLY) intravenously and via 2 methods of Iontophoresis (ION): one-patch and two-patch administration, with subsequent blood draws over…
- Conditions
- Spinal Cord Injuries, Constipation, Fecal Incontinence, Neurogenic Bowel
- Trial name
- NCT04027972
- Testing
- Combination of Neostigmine and Glycopyrrolate, I-Box by Dynatronics
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Anal Incontinence, Fecal Incontinence
Physical Therapy for Anal Incontinence
Anal incontinence is a significant public health problem estimated to affect 7-15% of women in the United States. Traditional rehabilitation strategies include biofeedback and Kegel exercises for pelvic floor muscle…
- Trial name
- NCT03252951
- Testing
- Eccentric Training, Concentric Training, Isometric Training
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- San Diego State University
Fecal Incontinence, Anal Incontinence
Medical and Economic Evaluation of a Magnetic Anal Sphincter for Patients With Severe Anal Incontinence
The purpose of this study is to compare 2 surgical treatments of severe fecal incontinence (defined as more than a major leak per week).
- Trial name
- MOS STIC (NCT01920607)
- Testing
- magnetic anal sphincter, sacral nerve stimulation
- Where
- France
- Volunteers
- 71 people
- Sponsor
- Nantes University Hospital
Obstetric Anal Sphincter Injury, Severe Perineal Trauma
CArE for OAsI Study: Care Pathways and Anorectal Evaluation for OASI Associated Incontinence
The aim of this study is to ascertain which pathways currently exist in relation to the follow up of patients with obstetric anal sphincter injury related incontinence.
- Conditions
- Obstetric Anal Sphincter Injury, Severe Perineal Trauma, Grade 3 Perineal Tear, Grade 4 Perineal Tear
- Trial name
- CArE for OAsI (NCT06143072)
- Where
- United Kingdom
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- London North West Healthcare NHS Trust
Faecal Incontinence
Best Surgical Technique for Optimal Lead Placement in Sacral Neuromodulation - a Comparative Cadaver Study
Sacral neuromodulation (SNM) is an established treatment option for patients with faecal incontinence. The location of the stimulating electrode is considered to be essential for treatment success.
- Trial name
- NCT04726904
- Testing
- Sacral neuromodulation in conventional implantation technique
- Where
- Austria
- Volunteers
- 5 people
- Sponsor
- Medical University of Vienna
Constipation, Incontinence Bowel
Electronic Mobile Phone App Stool Diary
Our objective here is to improve the patient's compliance and accurate capture of patient reported bowel and abdominal symptoms, by utilizing a phone application that interactively records each bowel movement or leakage event and…
- Trial name
- NCT04644133
- Testing
- Paper diary, Electronic APP diary
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Augusta University