Clinical trials: Solid Tumor, completed
Advanced Solid Tumors
Dose Escalation Study of AUY922 in Advanced Solid Malignancies in Japan
This study will characterize the safety, tolerability, efficacy, pharmacokinetics, and pharmacodynamics of AUY922 in adult patients with advanced solid malignancies in Japan.
- Trial name
- NCT01132625
- Testing
- AUY922
- Where
- 2 sites in Japan
- Volunteers
- 37 people
- Sponsor
- Novartis Pharmaceuticals
Malignant Solid Neoplasm
Pharmacist-led Transitions of Care in the Outpatient Oncology Infusion Center for Patients With Solid Tumor
This trial studies how well pharmacist-led transitions of care works in the outpatient oncology infusion center for patients with solid tumor.
- Trial name
- NCT04122118
- Testing
- Medical Chart Review, Educational Intervention, Survey Administration
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Thomas Jefferson University
Advanced Solid Tumors
Phase 1 Study to Evaluate the Safety, Tolerability and Pharmacokinetic Profile of XNW7201 in Subjects With Advanced Solid Tumors
The research project is testing this potential new medication for advanced solid tumours. This research project is being done to get more information about the study drug (XNW7201).
- Trial name
- NCT03901950
- Testing
- XNW7201 tablets
- Where
- Australia
- Volunteers
- 45 people
- Sponsor
- Evopoint Biosciences Inc.
Anxiety, Depression
Brief CBT for Anxiety and Advanced Cancer
RATIONALE: Providing cognitive-behavioral therapy (CBT) may reduce anxiety and improve quality of life of patients with advanced cancer.
- Conditions
- Anxiety, Depression, Unspecified Adult Solid Tumor, Protocol Specific, Cancer
- Trial name
- NCT00706290
- Testing
- Brief Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Massachusetts General Hospital
Adult Solid Neoplasm, Lymphoma
Improving Communication in Older Cancer Patients and Their Caregivers
Over 60% of cancers occur in older persons, and the number of older persons with cancer is expected to grow as the population ages.
- Trial name
- COACH (NCT02107443)
- Testing
- Geriatric Assessment Summary, Geriatric Assessment Targeted Recommendations, Geriatric Assessment (GA)
- Where
- 19 sites in United States
- Volunteers
- 546 people, healthy volunteers welcome
- Sponsor
- Supriya Mohile
Kidney Cancer, Metastatic Cancer
Magnetic Resonance Imaging-guided Thermal Radiofrequencey Ablation of Primary Renal Cell Carcinoma, Hepatic Metastasis, and Other Sites of Solid Organ Tumor and Metastases
RATIONALE: Radiofrequency ablation uses high-frequency electric current to heat and kill tumor cells. Magnetic resonance imaging-guided radiofrequency ablation may an effective treatment for primary kidney cancer, liver…
- Conditions
- Kidney Cancer, Metastatic Cancer, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00006255
- Testing
- radiofrequency ablation, thermal ablation therapy
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Case Comprehensive Cancer Center
Cancer Genomic Profiling
A Study to Learn More About What Japanese Patients With Solid Tumors Think About Taking Medicine That is Based on Their Genetic Information
Researchers are looking for a better way to treat people with solid tumors. One new way is called cancer genomic medicine. In cancer genomic medicine, doctors use tests to look at the genetic information in a solid tumor.
- Trial name
- NCT04607889
- Testing
- Survey
- Where
- Japan
- Volunteers
- 605 people
- Sponsor
- Bayer
Oncology, Solid Tumor, Adult
Stratification of Patients in Oncogeriatrics and Personalization of Interventions
Multicenter randomized controlled trial. Patients will be randomly assigned to the control group or the intervention group in each of the health centers.
- Trial name
- ONKO-FRAIL (NCT05131113)
- Testing
- Physical exercise
- Where
- 3 sites in Spain
- Volunteers
- 186 people
- Sponsor
- Biogipuzkoa Health Research Institute
Advanced Solid Tumors
A Trial to Evaluate Safety and Tolerability of SHR-1316 in Cancer Patients
In many types of human tumors, PD-L1 is highly expressed. Such high expression has often been associated with poor prognosis in cancer patients.
- Trial name
- NCT03133247
- Testing
- SHR-1316
- Where
- Australia
- Volunteers
- 37 people
- Sponsor
- Atridia Pty Ltd.
Pancreatic Cancer, Pancreatic Neoplasms
Intermittent Suction Technique in the Diagnosis of Pancreatic Solid Lesions
The aim of this study is to compare the diagnostic yield of intermittent versus continuous suction in the diagnosis of pancreatic solid lesions.
- Trial name
- NCT03829748
- Testing
- Intermittent aspiration
- Where
- Spain
- Volunteers
- 33 people
- Sponsor
- Fundación de Investigación Biomédica - Hospital Universitario de La Princesa
Elderly Patients, Solid Organ Cancer
Epidural Anesthesia and Long-term Outcomes in Elderly Patients After Surgery
Surgical resection is one of the most important treatments for solid organ cancer. Whereas cancer recurrence and/or metastasis are the major reasons of treatment failure.
- Conditions
- Elderly Patients, Solid Organ Cancer, Surgical Resection, Epidural Anesthesia
- Trial name
- NCT03335826
- Testing
- Combined epidural-general anesthesia, General anesthesia
- Where
- 5 sites in China
- Volunteers
- 1,802 people
- Sponsor
- Peking University First Hospital
Cancer, Neoplasm Metastasis
Open Label Phase 1 Dose Finding Study of TRC105 in Patients With Solid Cancer
This study is being performed to evaluate the safety and tolerability of the TRC105 monoclonal antibody.
- Trial name
- NCT00582985
- Testing
- TRC105 chimeric anti-CD105 antibody
- Where
- 4 sites in United States
- Volunteers
- 51 people
- Sponsor
- Tracon Pharmaceuticals Inc.
Neoplasms, Breast Neoplasms
A Study Of Oral Palbociclib (PD-0332991), A CDK4/6 Inhibitor, As Single Agent In Japanese Patients With Advanced Solid Tumors Or In Combination With Letrozole For The First-Line Treatment Of Postmenopausal Japanese Patients With ER (+) HER2 (-) Advanced Breast Cancer
This study is comprised of two portions: a Phase 1 portion and a Phase 2 portion. The Phase 1 portion is a single-country, non-randomized, open label, clinical trial which will evaluate the safety, tolerability, preliminary…
- Trial name
- NCT01684215
- Testing
- PD-0332991, letrozole
- Where
- 16 sites in Japan
- Volunteers
- 61 people
- Sponsor
- Pfizer
Solid Tumor
A Study in Participants With Advanced Solid Tumors
This trial is testing ramucirumab (LY3009806) administered to Chinese participants with advanced solid tumors that are resistant to standard therapy or for whom no standard therapy is available.
- Trial name
- NCT01682135
- Testing
- Ramucirumab
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Eli Lilly and Company
Solid Tumor, Metastatic Colorectal Cancer
XAD - Xelox (Capecitabine + Oxaliplatin) + Bevacizumab + Dasatinib
The primary purpose of this study is to find the highest tolerated dose of the study drugs: capecitabine, oxaliplatin, bevacizumab, and dasatinib given in combination to subjects with advanced solid tumors.
- Trial name
- XAD (NCT00920868)
- Testing
- dasatinib, bevacizumab, Oxaliplatin
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- Herbert Hurwitz, MD
Unspecified Adult Solid Tumor, Protocol Specific
Topotecan Plus Sargramostim in Treating Patients With Advanced Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Colony-stimulating factors such as sargramostim may increase the number of immune cells found in bone marrow…
- Trial name
- NCT00002950
- Testing
- sargramostim, topotecan hydrochloride
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Yale University
Malignant Glioma, Hepatocellular Carcinoma
Early-Phase Safety of Proton Therapy Equipment
The main purpose of this study is to collect the safety data of Sumitomo Heavy Industries' proton therapy equipment for the treatment of solid cancer patients in Linkou Chang Gung Memorial Hospital, including the patients'…
- Conditions
- Malignant Glioma, Hepatocellular Carcinoma, Head and Neck Malignant Tumor, Prostate Cancer
- Trial name
- NCT02315989
- Testing
- proton therapy
- Where
- Taiwan
- Volunteers
- 6 people
- Sponsor
- Chang Gung Memorial Hospital
ADVANCED SOLID TUMORS
Phase I, Multicenter, Open-label, Dose-escalating, Clinical and Pharmacokinetic Study of PM01183 in Patients With Advanced Solid Tumors
This is a phase I, multicenter, open-label, dose escalating clinical and pharmacokinetic study of PM01183 for patients with advanced solid tumors
- Trial name
- NCT00877474
- Testing
- PM01183
- Where
- 2 sites in United States, Spain
- Volunteers
- 30 people
- Sponsor
- PharmaMar
Recurrent Lymphoma, Refractory Lymphoma
Vinblastine and Temsirolimus in Pediatrics With Recurrent or Refractory Lymphoma or Solid Tumours Including CNS Tumours
The purpose of this study is to determine the best dose of vinblastine that can be given with a new drug, temsirolimus.
- Conditions
- Recurrent Lymphoma, Refractory Lymphoma, Solid Tumours, Central Nervous System
- Trial name
- NCT02343718
- Testing
- Vinblastine, Temsirolimus
- Where
- 6 sites in Canada
- Volunteers
- 7 people
- Sponsor
- Canadian Cancer Trials Group
Advanced Solid Tumors
A Study of IMC-A12 in Participants With Tumors Who No Longer Respond to Treatment or For Whom No Treatment is Available
The purpose of this study is to determine if IMC-A12 is safe for participants, and also to determine the best dose of IMC-A12 to give to participants.
- Trial name
- NCT00785538
- Testing
- IMC-A12
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Eli Lilly and Company