Clinical trials: Solitary Pulmonary Nodule
SPN, Lung Cancer
Augmented Reality-assisted Localization of Solitary Pulmonary Nodules for Precise Sublobar Lung Resection
With the popularization of CT screening, the detection rate of small lung nodules has greatly increased. Therefore, the clinical thoracoscopic lung nodule biopsy and sub-lobectomy for radical resection of lung cancer are greatly…
- Trial name
- ARPL (NCT05162235)
- Testing
- Augmented Reality-assisted localization of solitary pulmonary nodule
- Volunteers
- 20 people
- Sponsor
- Shanghai Chest Hospital
Lung Cancer, Multiple Pulmonary Nodules
Real World Registry for Use of the Ion Endoluminal System
The primary objective of this study is to evaluate the performance of the Ion Endoluminal System with real-world use for pulmonary lesion localization or biopsy.
- Conditions
- Lung Cancer, Multiple Pulmonary Nodules, Lung Neoplasms, Respiratory Tract Neoplasms
- Trial name
- NCT06004440
- Testing
- Ion Endoluminal System
- Where
- 16 sites in United States
- Volunteers
- 1,301 people
- Sponsor
- Intuitive Surgical
Pulmonary Nodules
Robotic-Assisted Bronchoscopy-Guided Synchronous Biopsy and Radiofrequency Ablation for Pulmonary Nodules
This is a prospective, single-arm, open-label clinical study. The primary study objective is to evaluate the feasibility of synchronous biopsy and radiofrequency ablation for pulmonary nodules under robotic-assisted bronchoscopy.
- Trial name
- NCT07545057
- Testing
- Robotic-assisted bronchoscopy-guided synchronous biopsy and radiofrequency ablation for pulmonary nodules
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Shanghai Chest Hospital
Solitary Pulmonary Nodule
Tubeless VATS for Peripheral Lung Nodule
Chest tube placement after thoracoscopy surgery had been generally accepted as routine procedure for removal of the residual intrapleural fluid and air, however, it would cause post-operative pain, prohibit ambulation after…
- Trial name
- NCT02817048
- Testing
- chest tube, VATS without chest tube placement, VATS with chest tube placement
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Multiple Pulmonary Ground-Glass Nodules, Lung Neoplasms
Nebulized Inhalation of Recombinant Human p53 Adenovirus Injection for Treatment of Multiple Ground-Glass Lung Nodules: A Single-Arm Clinical Study
This study aims to evaluate the safety and efficacy of nebulized inhalation of Recombinant Human Ad-p53 Injection (Gendicine®) for the treatment of multiple ground-glass lung nodules.
- Conditions
- Multiple Pulmonary Ground-Glass Nodules, Lung Neoplasms, Precancerous Conditions
- Trial name
- NCT07150416
- Testing
- Recombinant Human Ad-p53 Injection
- Where
- China
- Volunteers
- 38 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Solitary Pulmonary Nodule, Coin Lesion, Pulmonary
The Watch the Spot Trial
This study will compare two clinically accepted protocols for surveillance imaging in individuals who are found to have a small pulmonary nodule on chest computed tomography (CT) scans.
- Conditions
- Solitary Pulmonary Nodule, Coin Lesion, Pulmonary, Lung Neoplasms, Carcinoma, Non-small-cell Lung
- Trial name
- WTS (NCT02623712)
- Testing
- More Frequent Surveillance Strategy, Less Frequent Surveillance Strategy
- Where
- United States
- Volunteers
- 34,686 people
- Sponsor
- Kaiser Permanente
Lung Neoplasms, Pulmonary Nodule, Solitary
LungVision AI-Augmented Fluoroscopic Navigation for Intraoperative Pulmonary Nodule Localization
This prospective single-center pilot study evaluates the clinical feasibility, localization accuracy, and safety of the LungVision system-an AI-augmented fluoroscopic navigation platform-for real-time intraoperative localization…
- Conditions
- Lung Neoplasms, Pulmonary Nodule, Solitary, Carcinoma, Non-Small-Cell Lung
- Trial name
- NCT07682012
- Testing
- LungVision System, Preoperative Dual Localization
- Where
- Taiwan
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Peripheral Pulmonary Lesion
Evaluate the Diagnostic Value of BTPNA for PPL: a Real-world Study
The study is designed as a multicenter prospective trial of BTPNA for the diagnosis of peripheral pulmonary lesions in the real world.
- Trial name
- NCT04597346
- Testing
- Bronchoscopic Transparenchymal Nodule Access
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai Chest Hospital
Solitary Pulmonary Nodules
Clinical Evaluation of CARESTREAM Dual Energy and Digital Tomosynthesis
The purpose of this study is to evaluate the imaging performance of Dual Energy and Digital Tomosynthesis (DE-DT) application against the commercially available predicate devices.
- Trial name
- NCT02531646
- Testing
- Radiation
- Volunteers
- 66 people
- Sponsor
- Carestream Health, Inc.
Solitary Pulmonary Nodule
Usefulness of Interferon-gamma Release Assay in Diagnosing Pulmonary Nodules
Among the causes of the solitary pulmonary nodule (SPN), benign causes including tuberculosis was noted on 15 to 60 percents in various studies.
- Trial name
- NCT01149187
- Where
- 2 sites in South Korea
- Volunteers
- 400 people
- Sponsor
- Seoul National University Hospital
Pulmonary Nodule, Pneumothorax
Safety And Recovery Of Tubeless Strategy In Uniportal VATS Wedge Resection
Brief Summary The goal of this clinical trial is to evaluate the safety and recovery outcomes of different tubeless strategies in adult patients undergoing uniportal video-assisted thoracoscopic (VATS) wedge resection who are…
- Conditions
- Pulmonary Nodule, Pneumothorax, Postoperative Complications
- Trial name
- NCT07395349
- Testing
- Conventional Chest Tube Drainage, Single Intraoperative Aspiration Tubeless, Double Intraoperative Aspiration Tubeless
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Lung Cancer Diagnosis
DNA Methylation Combined With Artificial Intelligence Imaging to Identify Lung Nodules
Lung cancer is the leading cause of cancer deaths,and the key to reducing mortality in lung cancer patients is early diagnosis and treatment.Currently,peripheral blood DNA methylation is a novel in vitro molecular marker for…
- Trial name
- MAGIC (NCT06220305)
- Testing
- DNA methylation joint AI imaging
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Pulmonary Nodule, Solitary
A Clinical Study of Optimized CT-guided Pulmonary Nodule Microcoil Localization Technique
In the early stage of the study, the CT-guided micro-coil locating method for pulmonary small nodules was optimized. This study will use a single set of target values non-randomized controlled trials to evaluate the safety and…
- Trial name
- NCT03649906
- Testing
- Optimized Localization Technique
- Where
- China
- Volunteers
- 125 people
- Sponsor
- Beijing Aerospace General Hospital
Percutaneous Pulmonary Nodule Biopsy
CT-guided Needle Guidance Using Stereotaxic Unit, Navigation Versus Conventional Biopsy Technique for the Percutaneous Pulmonary Nodule Biopsy
The purpose of this study was to compare the safety and efficacy of CT-guided needle guidance using stereotaxic unit, navigation versus conventional biopsy technique for the patients scheduled to undergo percutaneous pulmonary…
- Trial name
- NCT03321994
- Testing
- stereotaxic unit, navigation, conventional biopsy technique
- Volunteers
- 106 people
- Sponsor
- Hyung Jin Won
Pulmonary Nodule, Solitary
The Benefit of UHR-CT: Precision of Repeated Volume Measurements of Pulmonary Nodules
To assess the variability of semi-automated volume measurements of pulmonary nodules on same-day repeated scans of equal radiation dose from two different CT scanners: One high-end CT scanner with standard spatial resolution…
- Trial name
- Coffee Break (NCT04209972)
- Testing
- Precision Ultra-High-Resolution CT scanner, Genesis high-end CT scanner
- Where
- Netherlands
- Volunteers
- 92 people
- Sponsor
- Radboud University Medical Center
Pulmonary Nodule, Solitary, Multiple Pulmonary Nodules
GE Healthcare VolumeRAD Lung Nodule Detection Study
To perform a multiple reader, multiple case (MRMC) observer study assessing the detection performance of VolumeRAD tomosynthesis of the chest in detecting lung nodules.
- Trial name
- NCT00963651
- Testing
- Chest tomosynthesis and X-ray
- Where
- 4 sites in United States, Sweden
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- American College of Radiology - Image Metrix
Pulmonary Nodule, Solitary, Lung Cancer
Clinical Utility of Management of Patients With Pulmonary Nodules Using the Percepta Nasal Swab Classifier
The goal of this observational study is to learn how a physician uses the results of the Percepta® Nasal Swab test to manage people with a newly identified pulmonary nodule.
- Trial name
- NIGHTINGALE (NCT06426628)
- Where
- 23 sites in United States, Puerto Rico
- Volunteers
- 2,400 people
- Sponsor
- Veracyte, Inc.
Benign and Malignant Solitary Pulmonary Nodules
(PET) Imaging in the Management of Patients With Solitary Pulmonary Nodules
All patients with a new, untreated solitary pulmonary nodule (SPN) between 7 mm and 3 cm in diameter identified by chest x-ray, will be approached to undergo positron emission tomography (PET) and computerized tomography (CT).
- Trial name
- NCT00032331
- Testing
- PET Imaging, CT scan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Pulmonary Nodule, Solitary
The MDA Test to Differentiate of Benign and Malignant Pulmonary Nodules
The purpose of the study is the identification of the efficacy of MDA Test to Differentiate of Benign and Malignant Pulmonary Nodules.
- Trial name
- NCT03790735
- Testing
- FISH
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Lung Ground-glass Opacities, Active Surveillance
Active Surveillance for Limited GGNs
This study is a single-arm, multi-center, phase III trial conducted under the Eastern Cooperative Thoracic Oncoloy Project (ECTOP) .
- Trial name
- NCT06394037
- Testing
- Active surveillance
- Where
- China
- Volunteers
- 387 people
- Sponsor
- Fudan University