Clinical trials: Somatic Symptom
Somatization Disorder, Somatoform Disorders
Acceptance and Commitment Group Therapy for Adolescents With a Range of Functional Somatic Syndromes
Background: An increasing number of adolescents report recurrent functional somatic symptoms. Some experience persistent symptoms and may receive functional somatic syndromes (FSS) diagnoses (i.e.
- Trial name
- NCT02346071
- Testing
- Acceptance and Commitment Therapy, Enhanced Usual Care (EUC)
- Where
- Denmark
- Volunteers
- 91 people
- Sponsor
- University of Aarhus
Stress, Healthy
The Efficacy of Pasteurised Akkermansia Muciniphila in Healthy Medical Workers
Gut microbiota alterations secondary to chronic stress might serve as a triggering factor towards manifestation of somatic and mental symptoms. The administration of pasteurised A.
- Conditions
- Stress, Healthy, Dietary Supplement
- Trial name
- MENTAkHEALTH (NCT05738746)
- Testing
- Pasteurized Akkermansia muciniphila
- Where
- 2 sites in Poland
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
Colonic Polyp, Colon Cancer
Endoscopic Characteristics of Colonic Tumours
The purpose is to investigate whether polyps that look different at colonoscopy, have formed via different mutations and have different risks of turning into cancer.
- Trial name
- C-LST (NCT01372696)
- Testing
- Sample of polyp
- Where
- Australia
- Sponsor
- Professor Michael Bourke
Chronic Pain, Migraine
Evaluation of a Mind-Body Based Approach for Chronic Pain Treatment
The investigators are evaluating the effects of a mind-body mobile application, in combination with a guided movement program, on the experience of chronic pain.
- Conditions
- Chronic Pain, Migraine, Chronic Pain Syndrome
- Trial name
- NCT07143396
- Testing
- Mind-body mobile application and guided movement
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of the Fraser Valley
Hypnosis, Autoimmune Diseases
Hypnosis in Internal Medecine
Description of the short and long-term impact of hypnosis sessions for patient having benefited from at least one hypnosis session in internal medicine at the french hospital "Groupe Hospitalier Mutualiste de Grenoble", with the…
- Conditions
- Hypnosis, Autoimmune Diseases, Medically Unexplained Symptoms
- Trial name
- HypnoMedIn (NCT04698824)
- Testing
- Hypnosis session
- Volunteers
- 70 people
- Sponsor
- University Hospital, Grenoble
Tinnitus
Somatic Tracking for Tinnitus
We are examining the effect of mindfulness meditation on attitudes towards tinnitus, as well as physical and psychological distress associated with the condition.
- Trial name
- NCT06895824
- Testing
- Mindfulness Meditation
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University College London Hospitals
Fibromyalgia (FM), Fibromyalgia
FIBROmyalgia: Somatic Tracking and Exercise Program Study
The goal of this clinical trial is to learn if the combination of two interventions is more effective in treating fibromyalgia symptoms than one intervention alone.
- Conditions
- Fibromyalgia (FM), Fibromyalgia, Fibromyalgia Syndrome
- Trial name
- FIBROSTEPS (NCT06922747)
- Testing
- Group exercising, Somatic tracking, General activity recommendaitons
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- University of Tromso
Somatoform Disorders, Globus Hystericus
Treatment of Globus Sensations With Psychotherapy
The purpose of this study is to determine whether psychotherapy (based on exposure techniques) is effective in the treatment of functional somatic symptoms (FSS)/Somatoform Disorders (as exemplified here in subjects with globus…
- Trial name
- NCT01590992
- Testing
- Exposure-based psychotherapy for somatic symptoms, Relaxation therapy
- Where
- Switzerland
- Volunteers
- 175 people
- Sponsor
- University Hospital, Basel, Switzerland
Chronic Pain, Somatic Pain
Pain Acceptance Training in Patients Experiencing Emotional Distress and Somatic Symptoms: Examination of Dialectical Thinking as a Mediating Factor
Somatic symptoms, including physical pain, are highly prevalent among mental health patients. Current treatments have limited effectiveness for these symptoms, primarily because of patients' diminished introspective capacity and…
- Conditions
- Chronic Pain, Somatic Pain, Comorbid Pain and Emotional Difficulties
- Trial name
- NCT07067619
- Testing
- Pain-acceptance intervention
- Where
- 2 sites in Israel
- Volunteers
- 100 people
- Sponsor
- University of Haifa
Neuropathic Pain, Depression
The Effect of Diet on Chronic Inflammation and Related Disorders Following Spinal Cord Injury
Spinal cord Injury (SCI) is a condition commonly associated with a state of chronic low-grade inflammation due to a variety of factors such heightened risk for infection and development of metabolic disorders.
- Conditions
- Neuropathic Pain, Depression, Cognitive Impairment, Somatic Neuropathy
- Trial name
- NCT02099890
- Testing
- Omega-3, Vegetation Protein Powder, InflanNox
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brock University
Depression - Major Depressive Disorder, Generalized Anxiety Disorder
Ultra-brief Psychological Treatments for Emotional Symptoms and Disorders
The main objective of this randomized clinical trial is to study if various modalities of brief (eight sessions) and ultra-brief (four sessions) transdiagnostic cognitive-behavioral treatment work for decrease emotional symptoms…
- Conditions
- Depression - Major Depressive Disorder, Generalized Anxiety Disorder, Generalized Anxiety, Anxiety
- Trial name
- UltraPsyBrief (NCT06909669)
- Testing
- Group ultra-brief transdiagnostic cognitive-behavioral therapy, Group brief transdiagnostic cognitive-behavioral therapy, Individual ultra-brief transdiagnostic cognitive-behavioral therapy
- Where
- 2 sites in Spain
- Volunteers
- 184 people
- Sponsor
- Universidad de Córdoba
Atrial Fibrillation (AF), Heart Failure
Somatic Health Screening for Adults in Outpatient Psychiatric Care in Denmark (SomaScreen)
People with severe mental illness have a substantially increased risk of undiagnosed and insufficiently treated somatic disease.
- Conditions
- Atrial Fibrillation (AF), Heart Failure, Asthma (Diagnosis), Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- SomaScreen (NCT07518446)
- Testing
- Somatic Health Screening for Adults in Outpatient Psychiatric Care in Denmark (SomaScreen)
- Where
- Denmark
- Volunteers
- 2,800 people
- Sponsor
- Amager Hospital
Overactive Bladder, Non Obstructive Urinary Retention
Sacral Neuromodulation and Pudendal Somatic Afferents
Sacral neuromodulation is a well-excepted minimally invasive procedure for the treatment of overactive bladder and non-obstructive urinary retention.A tined lead with 4 stimulation electrodes is placed through the third or fourth…
- Trial name
- NCT03614754
- Testing
- Somatosensory evoked potentials
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universiteit Antwerpen
Somatic Symptom Disorder
Effects of COVID-19 Forced Isolation Context on Adolescents With and Without Somatic Symptom Disorder
The purpose of this study is to evaluate whether a forced isolation context (such provided by the ongoing Covid-19 pandemic restrictive measures) could reduce the burden of somatic symptoms among a group of patients with Somatic…
- Trial name
- NCT05795803
- Testing
- Forced isolation context
- Where
- Italy
- Volunteers
- 115 people
- Sponsor
- IRCCS Burlo Garofolo
Paraganglioma, Pheochromocytoma
Development of a Predictive Model for the Risk of Metastatic Disease in PPGLs, a Retrospective Cohort Study
Phaeochromocytomas and paragangliomas (PPGLs) are tumours of the adrenal medulla and extra-adrenal sympathetic nervous system, some which can become metastatic. It is a very rare disease and the tumours are often detected late.
- Conditions
- Paraganglioma, Pheochromocytoma, Genetic Predisposition to Disease, Pathology
- Trial name
- PPGL-Pred (NCT04788927)
- Where
- 2 sites in Denmark
- Volunteers
- 400 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Psychological Factors Affecting Other Medical Conditions, Somatic Symptom and Related Disorders
Exposure Therapy for Reactivity to Symptoms
It is unclear to what degree systematic exposure exercises contribute to the overall effects of exposure therapy (exposure and response prevention).
- Conditions
- Psychological Factors Affecting Other Medical Conditions, Somatic Symptom and Related Disorders, Bodily Distress Disorder
- Trial name
- SOMEX2 (NCT07757854)
- Testing
- Planned, systematic, exposure exercises, Response prevention
- Where
- Sweden
- Volunteers
- 360 people
- Sponsor
- Region Stockholm
Emphysema
Efficacy of Osteopathic Manipulation in Chronic Obstructive Pulmonary Disease
The purpose of this study is to determine if osteopathic manipulative treatment (OMT) is effective for persons with emphysema as a component of their chronic obstructive pulmonary disease.
- Trial name
- NCT00034112
- Testing
- osteopathic manipulative treatment
- Where
- United States
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Severe Health Anxiety, Somatic Symptom Disorder
Cognitive Behavior Therapy for Health Anxiety: A Comparison of Three Forms of Self-help
Background Severe health anxiety, Somatic symptom disorder or Illness anxiety disorder according to the Diagnostic and Statistical Manual of Mental Disorders 5 (DSM-5), is associated with considerable personal distress…
- Conditions
- Severe Health Anxiety, Somatic Symptom Disorder, Illness Anxiety Disorder
- Trial name
- NCT01966705
- Testing
- Cognitive Behavior Therapy, exposure and response prevention (Internet, guided), Cognitive Behavior Therapy, exposure and response prevention (Internet, unguided), Cognitive Behavior Therapy, exposure and response prevention (Book, unguided)
- Where
- Sweden
- Volunteers
- 132 people
- Sponsor
- Karolinska Institutet
Low Back Pain, Posttraumatic Stress Disorder
Low Back Pain and Comorbid Posttraumatic Stress Disorder
The aim is to test whether the psychotherapeutic intervention Somatic Experiencing targeting Post Traumatic Stress Disorder (PTSD) symptoms will have an additional positive effect on the outcomes of guided physiotherapy against…
- Trial name
- NCT03244046
- Testing
- Psychotherapy, Physiotherapy
- Volunteers
- 140 people
- Sponsor
- University of Southern Denmark
Acinar Cell Carcinoma, Adenoid Cystic Carcinoma
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors
This phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may…
- Conditions
- Acinar Cell Carcinoma, Adenoid Cystic Carcinoma, Adrenal Cortical Carcinoma, Adrenal Gland Pheochromocytoma
- Trial name
- NCT02834013
- Testing
- Biospecimen Collection, Computed Tomography, Echocardiography Test
- Where
- 1,007 sites in United States, Guam
- Volunteers
- 798 people
- Sponsor
- National Cancer Institute (NCI)