Clinical trials: Somatic Symptom Disorder, active
Functional Disorder
Patient Education and Duloxetine, Alone and in Combination, for Patients With Multisystem Functional Somatic Disorder
The goal of this clinical trial is to test if patient education or duloxetine can be used to treat multisystem functional somatic disorder (FSD).
- Trial name
- EDULOX (NCT06232473)
- Testing
- Patient Education, Duloxetine, Enhanced usual care
- Where
- Denmark
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Low Back Pain, Mechanical, Piriformis Syndrome
Strain-Counterstrain Treatment of Piriformis Pain
The purpose of this investigator-initiated study is to provide an efficient and non-invasive treatment option for pain caused by the piriformis muscle.
- Conditions
- Low Back Pain, Mechanical, Piriformis Syndrome, Somatic Dysfunction of Sacral Region (Finding)
- Trial name
- NCT05023005
- Testing
- Strain-Counterstrain treatment of piriformis muscle
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Bodily Distress Syndrome, Functional Somatic Disorder
DISTRESS Trial Functional Disorders - the DISTRESS Trial
A Diagnostic Clinic for Functional Somatic Disorders (FSD) has been set up at the outpatient diagnostic center at Regionshospitalet Silkeborg.
- Trial name
- DISTRESS (NCT06025617)
- Testing
- Diagnostic evaluation at the Diagnostic Clinic for Functional Disorders, Diagnostic as usual
- Where
- Denmark
- Volunteers
- 290 people
- Sponsor
- Regionshospitalet Silkeborg
Chronic Pain, Migraine
Evaluation of a Mind-Body Based Approach for Chronic Pain Treatment
The investigators are evaluating the effects of a mind-body mobile application, in combination with a guided movement program, on the experience of chronic pain.
- Conditions
- Chronic Pain, Migraine, Chronic Pain Syndrome
- Trial name
- NCT07143396
- Testing
- Mind-body mobile application and guided movement
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of the Fraser Valley
Paraganglioma, Pheochromocytoma
Development of a Predictive Model for the Risk of Metastatic Disease in PPGLs, a Retrospective Cohort Study
Phaeochromocytomas and paragangliomas (PPGLs) are tumours of the adrenal medulla and extra-adrenal sympathetic nervous system, some which can become metastatic. It is a very rare disease and the tumours are often detected late.
- Conditions
- Paraganglioma, Pheochromocytoma, Genetic Predisposition to Disease, Pathology
- Trial name
- PPGL-Pred (NCT04788927)
- Where
- 2 sites in Denmark
- Volunteers
- 400 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Post-traumatic Stress Disorder (PTSD), Trauma and Stress Related Disorders
Grappling With Trauma: Brazilian Jiu-Jitsu for First Responders
This study explores whether participating in an 8-week Brazilian Jiu-Jitsu (BJJ) program is linked to changes in trauma-related symptoms among first responders.
- Conditions
- Post-traumatic Stress Disorder (PTSD), Trauma and Stress Related Disorders, Occupational Stress, Emotional Regulation Difficulties
- Trial name
- CAM-GRIP (NCT07783516)
- Testing
- Brazilian Jiu-Jitsu Program
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Sam Houston State University
Somatic Symptom Disorder
Alexithymia and Attachment Style in Patients With Somatic Symptoms
To evaluate whether emotional awareness, attachment style and the ability to abstract and symbolize (IQ) influence the appearance of somatic symptoms.
- Trial name
- NCT05666921
- Testing
- psychological assessment
- Where
- 2 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Meyer Children's Hospital IRCCS
Depression / Major Depressive Disorder, Mental Health (Depression)
Stress Management and Meditative Movements for Asian Americans With Depression and Physical Symptoms
Many Asian Americans with depression also struggle with physical symptoms-such as pain, fatigue, or other forms of bodily discomfort-that occur at the same time.
- Trial name
- NCT07610928
- Testing
- Stress Management and Resiliency Training with Qigong/Tai Chi, Healthy Living Program
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Massachusetts General Hospital
Somatic Symptom Disorder (DSM-5), Impairment
An Ecological Momentary Intervention for the Reduction of Impairment in Somatic Symptom Disorder
Persistent somatic symptoms significantly impair the daily lives of individuals with Somatic Symptom Disorder (SSD). Negative psychological factors (NPFs), such as catastrophizing and negative affectivity, further compound this…
- Conditions
- Somatic Symptom Disorder (DSM-5), Impairment, Psychological Factors, Persistent Physical Symptoms
- Trial name
- NCT07646509
- Testing
- Music listening, Cognitive reappraisal, No intervention
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- University of Vienna
Refractory Constipation, Somatic Symptom Disorder (DSM-5)
Evaluation of Fluoxetine for Refractory Constipation With Somatic Symptom Disorder Features
This single-center, randomized, double-blind, placebo-controlled trial evaluates the efficacy and safety of fluoxetine (40 mg/day) versus placebo in 194 adults with refractory chronic constipation exhibiting Somatic Symptom…
- Conditions
- Refractory Constipation, Somatic Symptom Disorder (DSM-5), Functional Constipation (FC)
- Trial name
- REFLECT (NCT06506136)
- Testing
- Fluoxetine
- Volunteers
- 194 people
- Sponsor
- Zhifeng Zhao, PhD
Tinnitus
Somatic Tracking for Tinnitus
We are examining the effect of mindfulness meditation on attitudes towards tinnitus, as well as physical and psychological distress associated with the condition.
- Trial name
- NCT06895824
- Testing
- Mindfulness Meditation
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University College London Hospitals
Post COVID-19 Condition, Somatic Symptom Disorder
MR-spectroscopy in Post-covid Condition Prior to and Following a Yoga Breathing Intervention
From a clinical perspective, we find that many patients with Post COVID condition suffer from severe and debilitating shortness of breath, while routine pulmonary investigations fail to find the cause of the problems experienced.
- Trial name
- SpeCY (NCT05946512)
- Testing
- yoga, social contact
- Where
- Austria
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Prostate Cancer
Precision-Based Genomics in Prostate Cancer
Background: Prostate cancer is the most common cancer and the second leading cause of death in males in the United States. Researchers want to find additional gene mutations that may increase a man s risk for prostate cancer and…
- Trial name
- NCT04706663
- Where
- 11 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- National Cancer Institute (NCI)
Pain (Visceral, Somatic, or Neuropathic), Women of Reproductive Age
Virtual Menstrual Pain Approaches in Females
This research study is testing two self-care approaches that may help prevent or reduce period pain in young females with recurrent painful menstrual cramps.
- Conditions
- Pain (Visceral, Somatic, or Neuropathic), Women of Reproductive Age, Mental Disorder, Digital Health
- Trial name
- AABQ (NCT07497711)
- Testing
- Virtual Auricular Acupressure, Virtual Baduanjin Qigong Exercise, Self Education
- Where
- Singapore
- Volunteers
- 145 people
- Sponsor
- Nanyang Technological University
Somatic Symptom Disorder
Developing an Integrated Psychotherapy With Cognitive-behavioral Therapy and Biofeedback Therapy for Somatic Symptom Disorder
This research program is aimed to develop a integrative psychotherapy (including CBT and biofeedback therapy) and to examine its efficacy on treatment of somatic symptom disorder.
- Trial name
- NCT05792930
- Testing
- cognitive-behavioral therapy and biofeedback therapy
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Advanced Malignant Neoplasm, ATM Gene Mutation
Talazoparib in Treating Patients With Recurrent, Refractory, Advanced, or Metastatic Cancers and Alterations in the BRCA Genes
This phase II trial studies how well talazoparib works in treating patients with cancers that have returned after a period of improvement, do not respond to treatment, or have spread to other parts of the body, and have…
- Conditions
- Advanced Malignant Neoplasm, ATM Gene Mutation, BRCA1 Gene Mutation, BRCA2 Gene Mutation
- Trial name
- NCT02286687
- Testing
- Laboratory Biomarker Analysis, Pharmacological Study, Talazoparib
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- M.D. Anderson Cancer Center
Preterm Birth
Interdisciplinary E-health Based Follow-up of Preterm Born Children
The aim of the study is to assess mental and somatic symptoms of preterm born children at the ages of 2, 5 and 10 by a multidisciplinary team and to evaluate an app that screens for these symptoms.
- Trial name
- NeoUp (NCT06345664)
- Testing
- Diagnostics and intervention recommendations
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Fibromyalgia (FM), Fibromyalgia
FIBROmyalgia: Somatic Tracking and Exercise Program Study
The goal of this clinical trial is to learn if the combination of two interventions is more effective in treating fibromyalgia symptoms than one intervention alone.
- Conditions
- Fibromyalgia (FM), Fibromyalgia, Fibromyalgia Syndrome
- Trial name
- FIBROSTEPS (NCT06922747)
- Testing
- Group exercising, Somatic tracking, General activity recommendaitons
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- University of Tromso
Chronic Somatoform Disorders in Adolescents
Non-Medication Methods to Relieve Adolescents with Somatoform Disorders
This research aims to investigate the effects of Tai Chi and relaxation techniques on adolescents (12-19 years old) with chronic somatoform disorders.
- Trial name
- Tai Chi Ados (NCT06865833)
- Testing
- Tai Chi and Relaxation Intervention
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Aphasia, Development, Human
Cognitive Functioning in Adults With Somatic Diseases and General Population From a Biopsychosocial Perspective
The goal of this observational study is to investigate cognitive functioning profiles in adults with neurologically recognized aphasic syndromes and general population.
- Conditions
- Aphasia, Development, Human, Neuropathology
- Trial name
- NCT06365658
- Testing
- Psychological assessment
- Where
- Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Bartosz M. Radtke