Clinical trials: Somatoform Disorders
Bulimia Nervosa, Body Dysmorphic Disorder
An Open Label Trial of Memantine in the Treatment of Bulimia Nervosa and Body Dysmorphic Disorder
The primary objective of this 13-week clinical trial is to test the hypothesis that treatment with Memantine will significantly improve the symptoms of those suffering from either bulimia nervosa, purging type or suffering from…
- Trial name
- NCT01038128
- Testing
- Memantine
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Mclean Hospital
Body Dysmorphic Disorder, Obsessive-compulsive Disorder
Oxytocin Administration in BDD and OCD
The purpose of the current study is to investigate the effect of an acute administration of intranasal oxytocin, relative to placebo, on social cognitive impairments among individuals with body dysmorphic disorder and…
- Trial name
- NCT02671266
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Combat Disorders
Prospective Study of Veteran Health in Previously Deployed Soldiers
Background: Previous deployments like that to the Persian Gulf in 1991 produced veterans with post-deployment symptom-based health problems with no medical explanation.
- Trial name
- NCT00285246
- Where
- 2 sites in United States
- Volunteers
- 838 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Neuropathic Pain, HIV Neuropathy
Symptom Management Efficacy Study to Reduce Distal Neuropathic Pain
Distal sensory peripheral neuropathy (DSP) is a chronic, debilitating painful condition affecting quality of life in persons living with HIV.
- Conditions
- Neuropathic Pain, HIV Neuropathy, HIV/AIDS, Pain
- Trial name
- NCT03855111
- Testing
- Standard Acupuncture / Moxibustion, Individualized (Tailored) Active Acupuncture / Moxibustion
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- New York University
Functional Movement Disorder
Non-invasive Intermittent Theta Burst Stimulation of the Dorsolateral Prefrontal Cortex in Functional Movement Disorders
Background: Functional movement disorders (FMD) involve involuntary movements that are not due to a recognized neurological or medical cause. FMD can cause major disability.
- Trial name
- NCT05155059
- Testing
- MagStim
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Cannabis, HIV Neuropathy
Effect of Cannabis and Endocannabinoids on HIV Neuropathic Pain
Acute cannabis administration is reported to alleviate HIV neuropathic pain (HIV-NP), but there is limited knowledge about the effects of cannabis constituents (delta-9 tetrahydrocannabinol/THC and cannabidiol/CBD), the…
- Conditions
- Cannabis, HIV Neuropathy, Pain Syndrome
- Trial name
- NCT03099005
- Testing
- Cannabis
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of California, San Diego
Convulsion, Non-Epileptic, Conversion Disorder
Treatments for Psychogenic Nonepileptic Seizures (NES)
The investigators propose that treatment of the comorbid disorders (depression, anxiety, and impulsivity) with sertraline in patients with lone psychogenic nonepileptic seizures (NES), will result in a decreased number of NES.
- Conditions
- Convulsion, Non-Epileptic, Conversion Disorder, Depression, Stress Disorders, Post-Traumatic
- Trial name
- NES (NCT00159965)
- Testing
- sertraline
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Rhode Island Hospital
Hypochondriasis
Treatment of Hypochondriasis With CBT and/or SSRI
This study will compare the effectiveness of cognitive behavioral therapy, antidepressant medication, and a combination of the two for treating hypochondriasis.
- Trial name
- NCT00339079
- Testing
- Fluoxetine, Cognitive Behavioral Therapy (CBT), Supportive Therapy
- Where
- 2 sites in United States
- Volunteers
- 195 people
- Sponsor
- Brigham and Women's Hospital
Body Dysmorphic Disorder
Cognitive Behaviour Therapy (CBT) for Body Dysmorphic Disorder (BDD)
The aim of the research is to determine if Cognitive Behaviour Therapy (CBT) specific for BDD is more effective than a credible non-specific form of CBT for treating BDD and its delusional variant in adults aged 17 or over.
- Trial name
- NCT00871143
- Testing
- CBT specific for BDD, Non specific CBT
- Where
- United Kingdom
- Volunteers
- 46 people
- Sponsor
- Institute of Psychiatry, London
Pain Disorders
Crossover, Single Dose Randomized, Bioequivalence of Ketoprofen Lysine Salt Immediate Release vs Oral Solution
Objectives: The objective of the study was to investigate the bioequivalence between two formulations containing ketoprofen lysine salt (KLS) when administered as single oral doses in two consecutive study periods to healthy male…
- Trial name
- NCT02350296
- Testing
- KSL 40 mg, OKi® 80 mg
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dompé Farmaceutici S.p.A
Anxiety Disorders, Somatoform Disorders
Effectiveness of Escitalopram in the Treatment of Body Dysmorphic Disorder
This study's primary aim is to compare time to relapse and relapse rates in responders to acute escitalopram who are then randomized to placebo versus continuation treatment with escitalopram.
- Trial name
- NCT00149799
- Testing
- Escitalopram
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Functional Neurological Disorder
Body Signal Integration Training: A Case Series
The goal of this clinical trial is to learn about an intervention package in individuals with Functional Neurological Disorder (FND).
- Trial name
- NCT05941702
- Testing
- Body Signal Integration Training
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- University of Manchester
Body Dysmorphic Disorder
D-Cycloserine Augmentation of Behavior Therapy for Individuals With Body Dysmorphic Disorder
The purpose of the study is to conduct a double-blind, placebo-controlled study of D-cycloserine (DCS) augmentation of behavior therapy in individuals with Body Dysmorphic Disorder (BDD).
- Trial name
- BDD/DCS (NCT00842309)
- Testing
- d-cycloserine
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Massachusetts General Hospital
Conversion Disorder
Neuroimaging Biomarkers of Prognosis in Motor Functional Neurological Disorders
Functional Neurological Disorder (FND/ Conversion Disorder) is a highly prevalent and disabling neuropsychiatric condition. Motor FND symptoms include Nonepileptic Seizures, Functional Movement Disorders and Functional Weakness.
- Trial name
- NCT03398070
- Testing
- Standard of Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Inflammatory Bowel Diseases, Depressive Episode
Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health
This study is a large population-based analysis in the United Kingdom (UK) using routine primary care data to investigate the impacts on quality-of-life outcomes and use of healthcare services in people aged 5 - 25 years…
- Conditions
- Inflammatory Bowel Diseases, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorder
- Trial name
- NCT05206734
- Testing
- No specific intervention
- Where
- United Kingdom
- Volunteers
- 19,469 people, healthy volunteers welcome
- Sponsor
- Momentum Data
Body Dysmorphic Disorders
Smartphone-Administered App Treatment for Adults With Body Dysmorphic Disorder
The investigators are developing and testing a Smartphone-based cognitive behavioral therapy (CBT) "app" for body dysmorphic disorder (BDD).
- Trial name
- NCT03221738
- Testing
- App-Based Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Massachusetts General Hospital
Body Dysmorphic Disorder
CBT as an Adjunct to SRIs in the Treatment of BDD
The research project is a controlled pilot study of the efficacy of cognitive-behavioral therapy (CBT) as an adjunct to serotonin reuptake inhibitor (SRI) pharmacotherapy in body dysmorphic disorder (BDD).
- Trial name
- NCT00211809
- Testing
- Cognitive Behavioral Therapy, Venlafaxine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pain, Head, Pain Syndrome
Botulinum Toxin Versus Placebo Injections to Temporalis and Masseter Muscles
This study aims to determine whether the injection of botulinum toxin A or placebo (unpreserved 0.9% sodium chloride) into the masseter and temporalis muscles provides pain relief and improved jaw function in those who suffer…
- Conditions
- Pain, Head, Pain Syndrome, Temporomandibular Disorder, Myofascial Pain Syndrome
- Trial name
- NCT03223298
- Testing
- Botulinum toxin type A, 0.9% Sodium Chloride Injection
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Weill Medical College of Cornell University
Body Dysmorphic Disorder
Waitlist-Control Trial of Smartphone Cognitive Behavioral Therapy (CBT) for Body Dysmorphic Disorder (BDD)
The investigators are testing the efficacy of Smartphone-delivered cognitive behavioral therapy (CBT) treatment for body dysmorphic disorder (BDD).
- Trial name
- NCT03673046
- Testing
- Smartphone-delivered cognitive behavioral therapy (CBT) for body dysmorphic disorder (BDD)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Massachusetts General Hospital
Body Dysmorphic Disorder
Effectiveness of Levetiracetam in the Treatment of Body Dysmorphic Disorder
The purpose of this study is to assess the usefulness of a medication (Levetiracetam) for people with body dysmorphic disorder.
- Trial name
- NCT00265109
- Testing
- Levetiracetam
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Butler Hospital