Clinical trials: Somatosensory Function
Stroke
Peripheral Stimulation Neural Response
Few patients recover full hand dexterity after an acquired brain injury such as stroke. Repetitive somatosensory electrical stimulation (SES) is a promising method to promote recovery of hand function.
- Trial name
- NCT03176550
- Testing
- Transcutaneous electrical nerve stimulation
- Volunteers
- 8 people
- Sponsor
- University of California, San Francisco
Head and Neck Neoplasms, Dysesthesia
Prospective Analysis of Effect of Collagen Wrap Conduit on Radial and Ulnar Nerve Function Following Radial/Ulnar Forearm Free Flap Harvest
The purpose of this study is to determine whether collagen nerve conduits placed on exposed radial and ulnar nerves during radial and ulnar forearm free flap harvests will reduce the occurrence and degree of sensory nerve deficit.
- Trial name
- NCT03875833
- Testing
- Collagen Nerve Wrap Conduit
- Sponsor
- The University of Texas Health Science Center, Houston
Pain Management, Quality of Life
Neuroma-Associated Pain Management After Combat-Related Trauma in Ukraine
This multicenter interventional study in Ukraine is designed to compare the effectiveness of cryoablation and radiofrequency ablation in managing neuroma-associated pain following combat-related trauma.
- Conditions
- Pain Management, Quality of Life, Neuroma, Functional Outcome
- Trial name
- NAP-C/R (NCT07416448)
- Testing
- cryoablation, Radiofrequency ablation alone
- Where
- Ukraine
- Volunteers
- 100 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Dystonia
Brain Function in Focal Dystonia
Objectives The main objectives of this proposal are (1) to characterize motor learning abnormalities in patients with focal dystonia; (2) to show, using transcranial magnetic stimulation, that this abnormal motor learning went…
- Trial name
- NCT00102999
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cerebrovascular Accident
Ischemic Nerve Block to Improve Hand Function in Stroke Patients
This study will determine whether impaired hand function due to stroke can be improved by blocking nerve impulses to the unaffected arm.
- Trial name
- NCT00056706
- Testing
- Transient deafferentation
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Physical and Rehabilitation Medicine
Impact of Order of Movement on Nerve Root Function
the main objective of this study is to investigate if different neurodynamic test sequencing of the median nerve has a different impact on median nerve root function.
- Trial name
- NCT05813002
- Testing
- standard neural mobilization, Distal to proximal neural mobilization, proximal to distal neural mobilization
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Sharjah
Proprioception
Sensing of Leg Position and Movement
This study will collect information on how people sense leg position and movement. The findings may help scientists develop better ways to evaluate and treat joint problems.
- Trial name
- NCT00100919
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Stroke
Active Somatosensory Exercise for Chronic Stroke
The current work aims to examine whether the proposed rehabilitation training or exercise will eventually yield improvements in both motor and somatosensory aspects at one goal.
- Trial name
- ActSens (NCT04490655)
- Testing
- Active somatosensory training, Motor-based training
- Where
- 2 sites in Singapore
- Volunteers
- 9 people
- Sponsor
- Nanyang Technological University
Hyperalgesia, Allodynia
Fenobam on Heat/Capsaicin Induced Hyperalgesia in Healthy Volunteers
Our goal is to demonstrate that healthy volunteers treated with fenobam will develop a significantly reduced area of cutaneous hyperalgesia compared to volunteers treated with placebo, after exposure to the heat/capsaicin model…
- Trial name
- NCT01981395
- Testing
- Fenobam
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Laura Cavallone
Acute Stroke, Mechanical Thrombectomy
BraiN20® Monitoring in Acute Stroke Undergoing Thrombectomy
N20 somatosensory evoked potential (SEP) response shows high predictive accuracy of functional recovery in patients with acute ischemic stroke (AIS) undergoing endovascular thrombectomy (EVT).
- Trial name
- PROMISE20 (NCT06149754)
- Testing
- BraiN20(R) monitoring of N20 somatosensory evoked potential
- Where
- 3 sites in Spain
- Volunteers
- 65 people
- Sponsor
- Fundació Institut Germans Trias i Pujol
Hemiplegic Cerebral Palsy, Mirror Movement Therapy
Effectiveness of the Mirror Therapy for Improving Bimanual Performance, Somatosensory Function of the Impaired Upper Limb and Quality of Life in Children With Unilateral Spastic Cerebral Palsy
Background: Unilateral Spastic Cerebral Palsy (USPC) is caused by an injury in one brain hemisphere in the immature brain, and affects the contralateral side of the body, especially on the upper limb.
- Trial name
- NCT05244083
- Testing
- Mirror Therapy, Program without Mirror Therapy
- Where
- Spain
- Volunteers
- 22 people
- Sponsor
- Universitat Internacional de Catalunya
Carpal Tunnel Syndrome
Effects of Mirror Therapy on Pain and Function on Bilateral Carpal Tunnel Syndrom
The purpose of this study was to evaluate pain and function after mirror therapy as well as level of catastrophism in bilateral carpal tunnel syndrome patients
- Trial name
- MTSTC (NCT03169218)
- Testing
- Mirror therapy
- Where
- Spain
- Volunteers
- 18 people
- Sponsor
- Olga Del Pozo Blanco
Colorectal Cancer
Phase II Study of Minocycline for Reducing Symptom Burden in Colorectal Patients
The goal of this clinical research study is to learn if minocycline can reduce numbness, pain, and/or loss of motor function in patients with colorectal cancer. In this study, minocycline will be compared to a placebo.
- Trial name
- NCT01906008
- Testing
- Minocycline, Questionnaires, Sensory Test
- Where
- 2 sites in United States
- Volunteers
- 122 people
- Sponsor
- M.D. Anderson Cancer Center
Cervicogenic Headache, Proprioceptive Disorders
Manual Therapy vs. Multicomponent Exercise in Cervicogenic Headache
The purpose of this study is to compare the effects of manual therapy and a multicomponent exercise program on suboccipital muscle thickness, joint position sense, pain, central sensitization, balance, and kinesiophobia in…
- Conditions
- Cervicogenic Headache, Proprioceptive Disorders, Neck Pain Musculoskeletal
- Trial name
- NCT07776093
- Testing
- Manual Therapy Protocol, Multicomponent Exercise Program
- Volunteers
- 32 people
- Sponsor
- Pamukkale University
Acute Pain, Neuroplasticity
HD-tDCS: Effects on the Somatosensory System
The purpose of this study is to investigate the efficacy of high definition tDCS on different cortical targets in modulating the nociceptive system in the healthy subjects.
- Conditions
- Acute Pain, Neuroplasticity, Brain Modulation, Somatosensory Function
- Trial name
- NCT04165876
- Testing
- Primary Motor Cortex Stimulation, Dorsolateral Prefrontal Cortex Stimulation, Multimodal Stimulation (DLPFC+M1)
- Where
- Denmark
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Knee Osteoarthritis, Amplification
Somatosensory Amplification and Psychological and Functional Status In Patients With Knee Osteoarthritis
As modern society enters the age of an aging population, the prevalence of knee OA continues to increase, which necessitates multi-faceted research.
- Conditions
- Knee Osteoarthritis, Amplification, Kinesiophobia, Psychological Disability
- Trial name
- NCT06753019
- Testing
- survey assessment tools
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Suleyman Demirel University
Amputation of Lower Limb Below Knee, Unilateral
Safety and Efficacy of Vibro-tactile Feedback for Patients Who Underwent Lower Limb Amputation
Prosthetics research has grown recently, focusing on bionic approaches that restore bodily functions with technical aids. One method involves using prostheses with feedback systems, which measure physical parameters and provide…
- Trial name
- NCT05895253
- Testing
- vibrotactile ground-contact feedback
- Where
- Austria
- Volunteers
- 18 people
- Sponsor
- Ludwig Boltzmann Institute for Traumatology - The research center in cooperation with AUVA
Postural Balance, Fall
Community-based Tai Chi, Balance, and Fall Risk
Aims: Examine the effects of a community Tai Chi program on measures of balance and sensorimotor function. Methods: In a pre-test and post-test design, balance was measured in older adults (N=344; 73.4±7.4 years) with 30-second…
- Conditions
- Postural Balance, Fall, Proprioceptive Disorders
- Trial name
- NCT04173936
- Testing
- tai chi
- Where
- United States
- Volunteers
- 405 people
- Sponsor
- University of North Carolina at Asheville
Cerebral Palsy, Somatosensory Disorders
The Effect Of Somatosensory Perceptıon And Proprıoceptıon On Upper Extremıty Functıonal Skılls
Cerebral Palsy (CP) is a non-progressive neurodevelopmental disorder characterized by posture and movement disorders as a result of damage to the immature brain for any reason before, during or after birth.In addition to tone…
- Conditions
- Cerebral Palsy, Somatosensory Disorders, Upper Extremity Dysfunction, Proprioceptive Disorders
- Trial name
- CP (NCT05213715)
- Testing
- assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Stroke, Proprioceptive Disorders
Effects of Proprioceptive Activities on Hand Function in Chronic Stroke Patients
To determine effects of proprioceptive activities on hand function in chronic stroke patients
- Trial name
- NCT05087719
- Testing
- experimental group, conventional treatment
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University