Clinical trials: Sore-throat
Infectious Diseases, Healthy Subjects
Effect of the Consumption of a Fermented Milk on Common Infections in Shift-workers
This single-center, randomized, double-blind and controlled study aims to examine the effect of a fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel® = tested product) on the incidence of…
- Conditions
- Infectious Diseases, Healthy Subjects, Respiratory Tract Infections, Sore Throat
- Trial name
- NCT01033799
- Testing
- Fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel®), Non fermented dairy product (control)
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Dexmedetomidine, Lidocaine
Intravenous Lidocaine Plus Intratracheal Dexmedetomidine on Postoperative Sore Throat
Objective: The present study was to investigate the effect of intravenous lidocaine combined with intratracheal dexmedetomidine on postoperative sore throat in patients undergoing thyroid cancer surgery.
- Conditions
- Dexmedetomidine, Lidocaine, Sore Throat
- Trial name
- NCT06952309
- Testing
- Intracheal dexmedetomidine, Intravenous lidocaine, Intravenous lidocaine combined with intracheal dexmedetomidine
- Volunteers
- 144 people
- Sponsor
- Anqing Municipal Hospital
Postoperative Sore Throat
Comparison of Nebulized Ketamine With Nebulized Magnesium Sulfate for the Prevention of Postoperative Sore Throat
The aim of this study is to compare the efficacy of nebulized ketamine versus nebulized magnesium sulfate in reducing the incidence and severity of POST. Primary outcome To compare the incidence of POST method.
- Trial name
- NCT07381036
- Testing
- Ketamine nebulizer, Mg sulfate nebulizer
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sohag University
Anesthesia, Pain, Postoperative
The Evaluation of the Effect of Preoperatively Applied Throat Lozenge
Purpose:The aim of this study is to evaluate the effect of preoperative throat lozenge on pain relief in the postoperative period of the mucosal damage caused by intubation in patients who underwent operations in the head and…
- Trial name
- NCT06114771
- Testing
- strepsilis
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Sore Throat After Thyroid Surgery
Transcutaneous Electrical Acupoint Stimulation on Postoperative Pharyngeal Pain
Thyroid surgery is a common type of surgery in thyroid and breast surgery, mainly used to treat benign and malignant thyroid diseases.
- Trial name
- NCT07117123
- Testing
- Transcutaneous electrical acupoint stimulation, No electrical stimulation
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Value of Continuous Pressure Monitoring in Laryngeal Mask
Continuous Laryngeal Cuff Pressure Monitoring
The aim of this study is to evaluate the airway seal of LMA during intraoperative manipulation.
- Trial name
- NCT03654924
- Testing
- Laryngeal Mask
- Where
- Singapore
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Sleep Breathing Disorders, Tonsillitis
Continuous Intravenous Sufentanil Infusion for Postoperative Pain Management Following Tonsillectomy or Adeno-tonsillectomy in Children
Postoperative pain following tonsillectomy or adeno-tonsillectomy in children is severe and sometimes last for days. Sufentanil is used by epidural route for postoperative analgesia in children.
- Conditions
- Sleep Breathing Disorders, Tonsillitis, Adenoid Hypertrophy
- Trial name
- NCT02205580
- Testing
- continuous intravenous sufentanil 0.02μg•kg-1•h-1 infusion, continuous intravenous sufentanil 0.03μg•kg-1•h-1 infusion, continuous intravenous sufentanil 0.04μg•kg-1•h-1 infusion
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Jin Ni
Tonsillitis Streptococcal
Comparison of Intravenous Co-amoxiclav Versus Benzyl Penicillin
To compare intravenous Co-amoxiclav versus Benzyl penicillin in children with severe streptococcal tonsillitis in terms of efficacy, safety and cost effectiveness.
- Trial name
- NCT04215770
- Testing
- inj co-amoxiclav 50 units/kg/day vs inj Benzyl Penicillin 25000 units/kg/day
- Where
- Pakistan
- Volunteers
- 310 people
- Sponsor
- Combined Military Hospital, Pakistan
Postoperative Sore Throat, Cough, Hoarseness
Effect Of Intracuff Dexamethasone On Postoperative Sore Throat In Patients Undergoing Laparoscopic Cholecystectomy
Postoperative sore throat is the most common complication following general anesthsia with endotracheal intubation with incidence ranging from 21 to 65% Although usually self-limiting, it significantly affects patient's comfort…
- Trial name
- NCT07760272
- Testing
- Dexamethasone (0.1 mg/kg), Normal Saline (0.9% NaCl)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Covid19, Nasopharyngitis
BNO 1030 Extract (Imupret) in the Treatment of Mild Forms of COVID-19
According to WHO (World Health Organisation) data, about 40% of patients with COVID-19 (Corona Virus SARS-CoV-2) have a mild course of the disease, namely, cases of mild course are of great danger from the point of view of the…
- Conditions
- Covid19, Nasopharyngitis, Anosmia, Fever
- Trial name
- NCT04797936
- Testing
- BNO 1030, Standard care
- Where
- Ukraine
- Volunteers
- 133 people
- Sponsor
- Ivano-Frankivsk National Medical University
Sore Throat
Mucosal Injury Using Pharyngeal Packing
After approval of the Institutional Review Board and written patient´s informed consent patients with indication for surgery of the sinuses were randomly assigned to one of the two study groups.
- Trial name
- NCT02757300
- Testing
- Hypopharyngeal packing, Without Hypopharyngeal packing
- Sponsor
- Marienhospital Osnabrück
Sore Throat, Intubation;Difficult
Assessment of Post-operative Sore Throat After Scheduled General Anesthesia
Precise description of the technique for intubation or laryngeal mask placement during general anesthesia Research on factors that can influence sore throat due to the placement of an endobuccal or endotracheal device during…
- Trial name
- POST (NCT04115865)
- Testing
- Endotracheal sonde or laryngeal mask
- Sponsor
- University Hospital, Lille
Pharyngitis
Safety, Tolerability, and Pharmacokinetic Profile of Grammidin, a Metered Dose Topical Spray in Healthy Volunteers
This study aims to evaluate the safety, tolerability, and pharmacokinetic profile of the Grammidin, a metered dose topical spray, compared to Grammidin lozenges following single administration in healthy volunteers .
- Trial name
- NCT06859281
- Testing
- Grammidin neo, Grammidin, a metered dose topical spray
- Where
- Russia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Valenta Pharm JSC
Tonsillopharyngitis, Respiratory Tract Infection Viral
Safety and Efficacy of the Sore Throat Lozenges to Treat Acute Sore Throats
Aim of this study is to investigate safety and efficacy of A. Vogel Sore throat lozenges for the treatment of of acute sore throats
- Trial name
- NCT04139681
- Testing
- A. Vogels Sore Throat lozenges
- Where
- Bulgaria
- Volunteers
- 74 people
- Sponsor
- A. Vogel AG
Pharyngitis
Best Assessment of Sore Throat and Antibiotic Prescribing
This project aims to investigate if an organisational change of patient flow away from medical practitioners can reduce unnecessary antibiotic prescribing in patients attending with a sore throat as the main complaint.
- Trial name
- BASTA (NCT06114706)
- Testing
- Physicians assess patients, Nurses assess patients, Pharmacists assess patients
- Where
- 4 sites in Sweden
- Volunteers
- 450 people
- Sponsor
- Vastra Gotaland Region
Angina, Acute Bronchiolitis
Impact of a Multimodal Intervention on Antibiotic Prescribing for Respiratory Infections in Primary Care
Antimicrobial resistance (AMR), considered one of the greatest global threats by the WHO, justifies the development of initiatives to promote appropriate antibiotic use-especially in primary care, where most antibiotics in France…
- Conditions
- Angina, Acute Bronchiolitis, Acute Bronchitis, COPD Exacerbation (AECOPD)
- Trial name
- GRASP (NCT07359287)
- Testing
- Antibiotic prescribing according to guidelines
- Where
- France
- Volunteers
- 4,500 people
- Sponsor
- University Hospital, Caen
Cough
Safety and Efficacy Reconyl for Cough With/Without Sore Throat
This study is a prospective, randomized, double-blind and placebo-controlled study to find out if reconyl may relieve the acute cough with/without sore throat.
- Trial name
- NCT06510257
- Testing
- Reconyl
- Where
- 2 sites in Indonesia
- Volunteers
- 60 people
- Sponsor
- Dexa Medica Group
Post Operative Sore Throat, Dysphagia
Post-operative Sore Throat as Determined by Endotracheal Tube Inflation Technique
The purpose of this study is to test whether the incidence of sore throat and other tracheal co-morbidities such as dysphagia and hoarseness can be lessened by use of a cuff manometer at the beginning of surgery to inflate to the…
- Conditions
- Post Operative Sore Throat, Dysphagia, Hoarseness
- Trial name
- NCT01305265
- Testing
- cuff manometer
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Tonsillitis
Battlefield Auricular Acupuncture During Adult Tonsillectomies and Effect of Post op Pain and Nausea
The purpose of this study is to determine if auricular acupuncture significantly reduces post-operative pain in comparison to the standard of care.
- Trial name
- BFA (NCT02571075)
- Testing
- Auricular acupuncture
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Defense and Veterans Center for Integrative Pain Management
Sore Throat, Tonsillitis
The BLIS Study: a Feasibility Study Assessing Compliance, Acceptability and Colonisation With Different Dosing Regimens of the Probiotic Supplement Streptococcus Salivarius K12 (Bactoblis®) in Adults
Short title The BLIS study Full title A feasibility study assessing compliance, acceptability and colonisation with different dosing regimens of the probiotic supplement Streptococcus salivarius K12 (Bactoblis®) in adults…
- Conditions
- Sore Throat, Tonsillitis, Pharyngitis
- Trial name
- NCT04297878
- Testing
- probiotic supplement Streptococcus salivarius K12 (Bactoblis®)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Southampton