Clinical trials: Sound Sensitivity
Asthma
Pilot Study of Pioglitazone for the Treatment of Moderate to Severe Asthma in Obese Asthmatics
Asthmatics who are significantly overweight tend to have more severe symptoms, more flare ups, and are more likely to have poorly-controlled asthma when compared to other asthmatics.
- Trial name
- GLITZ Asthma (NCT00634036)
- Testing
- pioglitazone
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Fernando Holguin
Asthma
Vitamin D Supplementation During Pregnancy for Prevention of Asthma in Childhood
The aim of this study is to prevent asthma symptoms (recurrent wheeze) in childhood by supplementation with high dose vitamin D to the mother during pregnancy.
- Trial name
- ABCvitaminD (NCT00856947)
- Testing
- Cholecalciferol D3
- Where
- 2 sites in Denmark
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Copenhagen Studies on Asthma in Childhood
Asthma
The Comparison of Electronic Auscultation Coupled With CALSA and FRI; Repeatability of FRI Biomarkers
CALSA will be compared with FRI and the repeatability of the FRI parameters will be tested in a group of healthy volunteers and asthma patients.
- Trial name
- NCT02228018
- Testing
- CT-scan
- Where
- Belgium
- Volunteers
- healthy volunteers welcome
- Sponsor
- FLUIDDA nv
Asthma, Rhinitis
Oral Bacteria and Allergic Disease in Children
This study will see if bacteria differ between children who have allergies or asthma and children who do not have allergies or asthma. Previous research suggests that some bacteria may protect against allergies and asthma.
- Conditions
- Asthma, Rhinitis, Eczema, Respiratory Sounds
- Trial name
- NCT00438646
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Asthma, Wheezing
Pulmonary Epithelium, Immunology and Development of Asthma: Breathing Together
The investigators want to know why some babies wheeze and some of these go on to develop asthma. The investigators are going to find out if babies who develop wheeze and asthma have abnormal airway lining cells (taken from the…
- Trial name
- NCT04063631
- Where
- United Kingdom
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Autism Spectrum Disorder
The Listening Program® With Bone Conduction Headphones Changes Hypersensitivity to Sound and Behavioral Responses
There are limited approaches to specifically address auditory sensory over- and under-responsivity (SOR) in children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT05009095
- Testing
- The Listening Program® with bone conduction headphones
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Children's Health
Asthma, COPD
Differentiation of Asthma/COPD Exacerbation and Stable State Using Automated Lung Sound Analysis With LungPass Device
This observational study evaluates whether lung sound analysis with LungPass device can be used to differentiate exacerbation and stable state asthma and COPD.
- Trial name
- NCT05145894
- Testing
- Lung auscultation with LungPass device (electronic auscultation)
- Where
- Belarus
- Volunteers
- 200 people
- Sponsor
- Healthy Networks
Asthma
Epinephrine Inhalation Aerosol USP, CLINICAL STUDY-B3 FOR ASSESSMENT OF PHARMACOKINETICS
This study examines the pharmacokinetic profile of Armstrong's proposed Epinephrine Inhalation Aerosol USP, an HFA134a propelled Metered Dose Inhaler (MDI) (E004), using a stable isotope deuterium-labeled epinephrine…
- Trial name
- NCT01255709
- Testing
- Arm T1: Primatene Mist HFA, Arm T2: Primatene Mist HFA, Arm C: Primatene Mist (epinephrine inhalation aerosol, USP)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Amphastar Pharmaceuticals, Inc.
Wheeze
Treating Wheezing in Children With Hypertonic Saline (TWICS)
Hypothesis: substitution of nebulized 3% NaCl (HS) for the standard normal saline (NS) used in bronchodilator therapy for acute viral wheezing in all children under age 6 years will provide superior symptom relief leading to…
- Trial name
- TWICS (NCT01868932)
- Testing
- hypertonic saline, saline
- Sponsor
- Dr. Michael Flavin
Wheezing, Asthma
Allergy Immunotherapy for the Reduction of Asthma
In this clinical study we aim to determine the effect of allergy immunotherapy in decreasing asthma and allergy related disease in children who had multiple episodes of wheezing and who are at high risk for developing persisting…
- Conditions
- Wheezing, Asthma, Allergy
- Trial name
- AIR (NCT01028560)
- Testing
- Allergen extracts (subcutaneous injections), Standard of care
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Albert Einstein College of Medicine
Subject Presenting Wheeze, COPD
Wheeze Detection Using Aevice Medical Device
The primary objective of this study is to determine if Aevice Medical Device can detect wheeze as accurately as a physician through auscultation.
- Conditions
- Subject Presenting Wheeze, COPD, Asthma
- Trial name
- NCT05194436
- Testing
- AeviceMD
- Where
- Singapore
- Volunteers
- 35 people
- Sponsor
- Aevice Health Pte. Ltd.
Asthma
Randomized, Placebo/Active Crossover Dose-ranging Study for Safety and Efficacy in Asthma Patients.
The main objective of this study is to evaluate the efficacy and safety of the Armstrong's Epinephrine HFA-MDI (E004) formulation, in comparison to the Placebo (Placebo-HFA) and an Active Control (Epinephrine CFC-MDI), and to…
- Trial name
- NCT01025648
- Testing
- E004 (epinephrine inhalation aerosol), 90 mcg/actuation, E004 (epinephrine inhalation aerosol), 125 mcg, E004 (epinephrine inhalation aerosol), 220 mcg
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- Amphastar Pharmaceuticals, Inc.
Bronchial Asthma
Efficacy and Tolerability of Beclomethasone Plus Salbutamol in HFA pMDI Fixed Combination vs Beclomethasone Plus Salbutamol in CFC pMDI Fixed Combination in a 12-week Treatment Period of Adult Patients With Uncontrolled Asthma
The purpose of this trial is to verify if the test treatment BDP 250 mcg/salbutamol 100 mcg HFA pMDI fixed combination is non-inferior to BDP 250 mcg/salbutamol 100 mcg pMDI fixed combination given with the conventional CFC…
- Trial name
- NCT00528723
- Testing
- salbutamol 100 mcg, BDP/salbutamol HFA pMDI, BDP/salbutamol CFC pMDI
- Where
- 25 sites in Italy, Russia and 2 more
- Volunteers
- 180 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Loudness Hyperacusis, Autism Spectrum Disorder (ASD)
Transitional Intervention for Hyperacusis in Autism
The main goal of this clinical trial is to evaluate the effectiveness, benefits, and post-treatment persistence of an intervention for loudness hyperacusis in adults with autism spectrum disorder (ASD).
- Conditions
- Loudness Hyperacusis, Autism Spectrum Disorder (ASD), Hyperacusis
- Trial name
- TIHA (NCT07798297)
- Testing
- Transitional Intervention for Hyperacusis in Autism
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Central Florida
Recurrent Wheezing, Wheezing
Effect of Palivizumab on Later Recurrent Wheezing in Preterm Infants
The hypothesis of the present study is that the prophylaxis with palivizumab to prevent the severe RS virus infection during the infancy among preterm infants may reduce the risk of subsequent recurrent wheezing in childhood.
- Conditions
- Recurrent Wheezing, Wheezing, Asthma
- Trial name
- NCT01072552
- Where
- Japan
- Volunteers
- 444 people
- Sponsor
- Satoshi Kusuda
Childhood Asthma With Acute Exacerbation
Azithromycin Treatment of Hospitalized Children With Asthmatic Symptoms
The purpose of this double-blind, randomized, controlled clinical trial is to investigate the effect of a three-day azithromycin treatment versus placebo treatment in children aged 1-5 years who are hospitalized due to…
- Trial name
- COPSACazt (NCT05028153)
- Testing
- Azithromycin Oral Liquid Product
- Where
- Denmark
- Volunteers
- 320 people
- Sponsor
- Copenhagen Studies on Asthma in Childhood
Asthma, Bronchospasm
Epinephrine Inhalation Aerosol USP, a HFA-MDI Study for Assessment of Pharmacokinetics
This study examines the pharmacokinetic profile of Armstrong's proposed Epinephrine Inhalation Aerosol USP, an HFA-MDI (E004), using a stable isotope deuterium-labeled epinephrine (epinephrine-d3) to differentiate the…
- Conditions
- Asthma, Bronchospasm, Wheezing, Shortness of Breath
- Trial name
- NCT01188577
- Testing
- Epinephrine Inhalation Aerosol, HFA, Epinephrine Inhalation Aerosol
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Amphastar Pharmaceuticals, Inc.
Asthma, Wheezing
Lung Function and Structure in Healthy Infants and Infants With Recurrent Wheezing
Infants will be enrolled into this study in one of three groups. First, there will be a group of full term infants with no history of wheezing.
- Conditions
- Asthma, Wheezing, Infant
- Trial name
- NCT00507676
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Indiana University
Migraine
Study of Quality of Life in Subjects With Chronic or High-frequency Episodic Migraine and Associated Comorbidities Treated With Erenumab
Migraine is a very common, neurological disorder, characterized by recurrent episodes of headache, potential progression to more frequent and severe attack patterns, and associated symptoms.
- Trial name
- COMIG (NCT04114630)
- Testing
- erenumab 70mg/mL
- Where
- 27 sites in Spain
- Sponsor
- Novartis Pharmaceuticals
Asthma, Asthma in Children
Wearable Auscultation Device Validation in Children
This observational clinical study is an evaluation of a diagnostic tool through comparison. Similar to a validation study, the output of the RESP device will be compared to physician auscultation, surrogated by having an…
- Conditions
- Asthma, Asthma in Children, Wheezing, Pediatric Asthma
- Trial name
- NCT06112080
- Testing
- RESP™ Biosensor
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Strados Labs, Inc.