Clinical trials: Sound Therapy
Coronary Artery Disease, Atherosclerosis
SYNergy Stent® System Implantation With Mandatory Intra-VascularUltra-Sound Guidance and Dual Anti-Platelet Therapy
The purpose of this study is to see if one month of dual antiplatelet therapy (DAPT) combined with the placement of the Synergy® Stent with IVUS (intravascular ultrasound) is safe for patients who are at high risk of bleeding…
- Conditions
- Coronary Artery Disease, Atherosclerosis, Stent Placement
- Trial name
- SYNIVUS-DAPT (NCT03606642)
- Testing
- Dual Antiplatelet (DAPT) Therapy, The Synergy® stent
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- HonorHealth Research Institute
Language Development Disorders, Speech Sound Disorder
Manipulating Linguistic Complexity to Improve Child Language Treatment Outcomes
Phonological disorder (PD) and specific language impairment (SLI) directly impact a child's ability to communicate and are among the most prevalent developmental disorders.
- Trial name
- NCT03977701
- Testing
- Phonological treatment, Morpheme treatment
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- San Diego State University
Tennis Elbow
ITU Treatment for Chronic Epicondylitis Musculoskeletal Pain Reduction
This study evaluates the effectiveness, safety and patient tolerance for the use of Intense Therapeutic Ultrasound (ITU) for chronic, subcutaneous lateral Epicondylitis musculoskeletal tissue pain reduction began in July 2015 and…
- Trial name
- ITU (NCT03255733)
- Testing
- Intense Therapeutic Ultrasound Treatment
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Guided Therapy Systems
Speech Sound Disorder
staRt: Enhancing Speech Treatment With Smartphone-delivered Biofeedback
Previous research suggests that biofeedback can outperform traditional interventions for RSE, but no controlled studies have tested this hypothesis in the context of app-delivered biofeedback.
- Trial name
- staRt (NCT04474691)
- Testing
- Traditional articulation treatment, Visual-acoustic biofeedback
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- New York University
Wheezing
Using Tests in Preschool Children With Wheeze to Determine the Need for Inhaled Corticosteroid Therapy.
Wheezing is common in preschool children and affects quality of life. Although asthma treatments such as inhaled steroids (ICS), which reduce swelling (inflammation) in the airways are used in this age group, they are often…
- Trial name
- TAILOR (NCT04942483)
- Testing
- Blood eosinophil count, Atopic sensitization, FeNO (offline method)
- Where
- United Kingdom
- Volunteers
- 118 people
- Sponsor
- Imperial College London
Asthma, Wheezing
Treatment of Preschool Children With Upper Respiratory Tract Illnesses Using Azythromycin and Lower Respiratory Tract Symptoms Using Oral Corticosteroids.
This protocol is comprised of two separate, but linked, clinical trials for treating preschool-aged children with recurrent severe episodes of wheezing.
- Trial name
- APRIL - OCELOT (NCT01272635)
- Testing
- Azithromycin, Prednisolone
- Where
- 16 sites in United States
- Volunteers
- 607 people
- Sponsor
- Milton S. Hershey Medical Center
Speech Sound Disorders
New Therapeutical Perspectives in Cases of Phonological Disorders
The aim of this study is to verify phonological and auditory aspects of children submitted to traditional phonological therapy, phonological therapy using a software and placebo therapy in children with phonological disorders.
- Trial name
- NCT02935062
- Testing
- Traditional Phonological Therapy, Software Phonological Therapy- SIFALA
- Where
- 2 sites in Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Maria
Subjective Tinnitus
Tinnitus Retraining Therapy Trial
The primary purpose of the Tinnitus Retraining Therapy Trial (TRTT) is to assess the efficacy of tinnitus retraining therapy (TRT) as a treatment for severe debilitating tinnitus.
- Trial name
- TRTT (NCT01177137)
- Testing
- Conventional sound generator (SG), Standard of Care (SC), Directive Counseling (DC)
- Where
- 6 sites in United States
- Volunteers
- 151 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Post Traumatic Stress Disorder, Anxiety
The Effects of the Safe and Sound Protocol on PTSD Symptoms and Anxiety
The Safe and Sound Protocol (SSP) is a passive acoustic intervention that is designed as a "neural exercise" to promote efficient regulation of autonomic state.
- Trial name
- NCT04999852
- Testing
- Safe and Sound Protocol, Psychotherapy
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Indiana University
Snoring
Mandibular Advancement vs Home Treatment for Primary Snoring
This is a randomized controlled trial for non-apneic snorers. The primary goal of the study is to evaluate the efficacy of a mandibular advancement device (MAD) vs conservative treatment for adults with non-apneic snoring as…
- Trial name
- NCT05756647
- Testing
- Interventional Arm, Conservative treatment Arm
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Washington University School of Medicine
Tinnitus
Clinical Trial of Sound-Based Versus Behavioral Therapy for Tinnitus
The purpose of this study is to determine if a novel sound-based therapy in comparison to standard of care (cognitive behavioral therapy) results in reducing tinnitus-related effects for people with bothersome tinnitus.
- Trial name
- NCT03022084
- Testing
- Desyncra, Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- VA National Center for Rehabilitative Auditory Research
Speech Sound Disorder
Delineation of Sensorimotor Subtypes Underlying Residual Speech Errors
Children with speech sound disorder show diminished accuracy and intelligibility in spoken communication and may thus be perceived as less capable or intelligent than peers, with negative consequences for both socioemotional and…
- Trial name
- C-RESULTS (NCT03736213)
- Testing
- Visual-acoustic biofeedback, Ultrasound biofeedback
- Where
- 3 sites in United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- New York University
Snoring
Pilot Study of cNEP for the Treatment of Snoring
This pilot study will examine the efficacy and safety of continuous negative external pressure ("cNEP") for the treatment of chronic snoring in people without obstructive sleep apnea.
- Trial name
- NCT02767843
- Testing
- continuous negative external pressure (cNEP)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Sommetrics, Inc.
Asthma, Wheezing
AZithromycin Therapy in Preschoolers With a Severe Wheezing Episode Diagnosed at the Emergency Department
AZ-SWED is a parallel group, double blind, placebo control efficacy clinical trial with two separate hypotheses. The trial compared the 5-day outcome of preschool children presenting to an Emergency Department (ED) with an acute…
- Trial name
- AZ-SWED (NCT04669288)
- Testing
- Azithromycin
- Where
- 8 sites in United States
- Volunteers
- 840 people
- Sponsor
- University of Arizona
Speech Sound Disorder
Comparing Traditional and Biofeedback Telepractice Treatment for Residual Speech Errors
This study aims to evaluate the relative efficacy of biofeedback and traditional treatment for residual speech errors when both are delivered via telepractice.
- Trial name
- C-RESULTS TPT (NCT04625062)
- Testing
- Visual-acoustic biofeedback, Motor-based treatment
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- New York University
Apraxia of Speech, Aphasia, Acquired
Apraxia of Speech: Comparison of EPG Treatment (Tx) and Sound Production Treatment (SPT)
The purpose of the proposed research is to examine the effects of two treatment approaches on speech production involving speakers with chronic apraxia of speech (AOS) and aphasia.
- Conditions
- Apraxia of Speech, Aphasia, Acquired, Speech Disorders
- Trial name
- EPG&SPT (NCT02554513)
- Testing
- EPG Tx, SPT
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- VA Office of Research and Development
Obstructive Sleep Apnea
Validation of Safety and Efficacy for Night Shift Therapy
The purpose of this study is to assess the accuracy of Night Shift in the detection of supine sleep and efficacy of vibro-tactile feedback in restricting supine sleep.
- Trial name
- NCT02032706
- Testing
- Deliver therapy when the supine position is detected
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Advanced Brain Monitoring, Inc.
Asthma, Wheezing
Individualized Therapy For Asthma in Toddlers
The INFANT study will test whether, in preschool children 12-59 months of age with persistent asthma, the following Step 2 asthma therapies will provide similar degrees of asthma control: 1.
- Trial name
- INFANT (NCT01606306)
- Testing
- daily fluticasone propionate, Montelukast, as-needed fluticasone propionate
- Where
- 13 sites in United States
- Volunteers
- 300 people
- Sponsor
- Milton S. Hershey Medical Center
Chronic Plantar Fasciitis
Intense Therapeutic Ultrasound - Treatment for Chronic Plantar Fascia Musculoskeletal Pain Reduction
Double-blinded feasibility study for the treatment of pain related to chronic plantar fasciitis. A total 37 patients (27 treated and 12 control/sham treated) received 2 treatments, 2 weeks apart on subcutaneous plantar fascia…
- Trial name
- ITU (NCT03255655)
- Testing
- Intense Therapeutic Ultrasound Treatment - ITU
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Guided Therapy Systems
Obstructive Sleep Apnea, OSA
Dimethyl Fumarate for Obstructive Sleep Apnea
The overall purpose of this study is to determine whether the oral medication dimethyl fumarate is an effective treatment for obstructive sleep apnea in patients who are unable, unwilling, or uneager to use positive airway…
- Conditions
- Obstructive Sleep Apnea, OSA, Sleep Apnea
- Trial name
- NCT02438137
- Testing
- Dimethyl fumarate
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Michigan