Clinical trials: Spastic Cerebral Palsy
Spastic Cerebral Palsy
3D-Microscopic Muscle Architecture in Cerebral Palsy
The focus of this study is to understand and define the mechanisms of the altered muscle development and growth on a microscopic level within a long-term perspective in children with cerebral palsy and to relate these findings to…
- Trial name
- 3D-MMAP (NCT06584851)
- Where
- Belgium
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cerebral Palsy, Congenital, Muscle Spasticity
Effects of Functional Electrical Stimulation on Gait in Children With Cerebral Palsy
Cerebral palsy (CP) is the most common neuromuscular disorder among children, resulting from a non-progressive injury during early brain development which leads to impairment of movement and posture.
- Trial name
- NCT02462018
- Testing
- WalkAide
- Volunteers
- 20 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Cerebral Palsy (CP)
Effect of IASTM in Children With Diplegia
The aim was to evaluate the effect of using IASTM on passive ROM of the lower limbs and joint angles during gait in children with spastic diplegic CP.
- Trial name
- NCT07289386
- Testing
- IASTM therapy in addition to the selected physical therapy program, selected physical therapy program
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Cerebral Palsy, Spastic Diplegia
Effect of Physical Activity Intervention Children With Spastic Diplegia After Resistance Training
The purpose of this study is to investigate the effects of a 6-month physical activity intervention program on mobility and participation after the termination of a 6-week functional strengthening program for school-age children…
- Trial name
- NCT01367340
- Testing
- Loaded sit-to-stand resistance exercise, Physical activity intervention
- Where
- Taiwan
- Volunteers
- 32 people
- Sponsor
- National Taiwan University Hospital
Cerebral Palsy, Spastic
Altered Back Geometry and Mobility Function After Backward Walking Training in Children With Cerebral Palsy
PURPOSE: To assess the effect of backward walking training on back geometry and mobility function in children with hemiparetic cerebral palsy through a comparative analysis with forward walking training.
- Trial name
- NCT04981964
- Testing
- Exercise training
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Cairo University
Cerebral Palsy
The Effect of Selective Dorsal Rhizotomy on a Multidimensional Outcome Set in Children With Spastic Cerebral Palsy: a Retrospective Study
Cerebral palsy or CP is the single largest cause of childhood physical disability, with a prevalence of 2-3 per 1000 livebirths.
- Trial name
- NCT06340425
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cerebral Palsy (CP)
Effect of Aquatic Therapy Program on Balance in Children With Spastic Diplegic Cerebral Palsy
1. Evaluate the effect of a structured aquatic therapy programme on static balance in children with spastic diplegic cerebral palsy. 2. Assess the effect of the same programme on dynamic balance in this patient population. 3.
- Trial name
- NCT07669350
- Testing
- aquatic therapy, land exercise program
- Volunteers
- 50 people
- Sponsor
- Delta University for Science and Technology
Cerebral Palsy Spastic Diplegia
Virtual Reality Training With Sensory Integration On The Gross Motor Functions Of Lower Limb
The objectives of this study are To determine the effect of virtual reality on balance and gross motor functions of the lower limb in spastic diplegic cerebral palsy.
- Trial name
- NCT04467385
- Testing
- VR training + Sensory Integration therapy + conventional therapy, VR training + conventional therapy
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Cerebral Palsy, Hypertonia
Use of EMG to Assess Clinical Hypertonia
A handheld surface electromyography device will be tested by clinicians on children with limb hypertonia, and inter-rater reliability will be assessed with and without the device.
- Conditions
- Cerebral Palsy, Hypertonia, Spasticity, Dystonia
- Trial name
- NCT00472914
- Testing
- portable surface electromyography
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Southern California
Cerebral Palsy
Which is the Best Dose of Dysport in Helping With Hip Pain for Children With Cerebral Palsy?
The purpose of the study is to compare the effectiveness of 3 doses of Dysport (5, 10 or 15 Units/Kg/hip) in the management of chronic bilateral hip pain due to cerebral palsy in children/young people.
- Trial name
- NCT00455637
- Testing
- Botulinum toxin type A
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- Ipsen
Cerebral Palsy, Spasticity, Muscle
Investıgatıon Of The Effectıveness Of The Mollıı Suıt In Chıldren Wıth Ambulatory Cerebral Palsy
Cerebral Palsy (CP) is the most common developmental disorder in childhood. Individuals' independence in daily living activities and participation in education, games, social and community activities are restricted.
- Trial name
- NCT06109129
- Testing
- EXOPULSE Mollii Suit
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Kastamonu University
Spastic Cerebral Palsy
Forward Versus Backward Gait Training on Functional Abilities in Children With Spastic Cerebral Palsy
This study aims to compare the effects of forward versus backward gait training on functional abilities in children with spastic cerebral palsy.
- Trial name
- NCT07251751
- Testing
- control group ( designed physical therapy program), forward gait training, backward gait training
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Pediatrics, Muscle Spasticity
BOTOX® Open-Label Treatment in Pediatric Lower Limb Spasticity
This study will evaluate the long-term safety of BOTOX® (botulinum toxin Type A) for the treatment of pediatric lower limb spasticity.
- Conditions
- Pediatrics, Muscle Spasticity, Cerebral Palsy
- Trial name
- NCT01603641
- Testing
- Botulinum Toxin Type A
- Where
- 56 sites in United States, Hungary and 7 more
- Volunteers
- 370 people
- Sponsor
- Allergan
Hemiplegic Cerebral Palsy, Cerebral Palsy (CP)
Effects of Fun-Core (Child-Friendly Core Stabilization) Exercises on Balance and Functional Mobility in Children With Spastic Cerebral Palsy
A total of 54 children, aged between 6 and 12 years, diagnosed with hemiplegic cerebral palsy and not meeting the exclusion criteria, who registered at the outpatient clinics of the Department of Physical Medicine and…
- Conditions
- Hemiplegic Cerebral Palsy, Cerebral Palsy (CP), Core Stabilization, Exercise
- Trial name
- NCT07233824
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Istanbul University
Cerebral Palsy, Spastic
Analyzing the Effect of Trunk Training on Limbs in Children With Spastic Cerebral Palsy
The purpose of this study is to analyze if trunk training has effects on trunk, upper, lower extremity motor functions in children with spastic Cerebral Palsy.
- Trial name
- FTT (NCT02643160)
- Testing
- Functional Trunk Training
- Volunteers
- 38 people
- Sponsor
- Abant Izzet Baysal University
Cerebral Palsy, Spastic
Effectiveness of Virtual Reality on Functional Mobility During Treadmill Training in Children With Cerebral Palsy
Cerebral palsy (CP), which occurs as a consequence of brain damage, has multiple deficits such as a global reduction of motor cortical activity during movement execution and inadequate processing of corticospinal and…
- Trial name
- NCT05131724
- Testing
- Treadmill training with virtual reality, Treadmill training
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- University of Vic - Central University of Catalonia
Sjogren-Larsson Syndrome
ADX-629 Therapy for Sjogren-Larsson Syndrome
This research study will determine whether orally administered ADX-629 is safe and has biochemical efficacy in participants with Sjögren-Larsson syndrome (SLS), a rare inherited disorder of fatty aldehyde metabolism The disease…
- Trial name
- NCT05443685
- Testing
- ADX-629
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Nebraska
Cerebral Palsy, Movement Disorders in Children
Reliability of Range of Movement Measurements in Cerebral Palsy
The aim is to investigate the inter-rater reliability of passive range of motion (pROM) measurement with goniometer of knee extension and ankle dorsiflexion for children with unilateral spastic cerebral palsy (USCP) and secondary…
- Trial name
- NCT06295107
- Testing
- Ankle Passive Range of Movement (pROM), Knee Passive Range of Movement (pROM)
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Region Skane
Lower Limb Spasticity Due to Cerebral Palsy
Dose-response Study of Efficacy and Safety of Botulinum Toxin Type A to Treat Spasticity of the Leg(s) in Cerebral Palsy
The purpose of this study is to determine whether injections of Botulinum toxin type A into muscles of the leg(s) are effective in treating children/adolescents (age 2-17 years) with increased muscle tension/uncontrollable muscle…
- Trial name
- NCT01893411
- Testing
- IncobotulinumtoxinA (16 Units per kg body weight), IncobotulinumtoxinA (12 Units per kg body weight), IncobotulinumtoxinA (4 Units per kg body weight)
- Where
- 53 sites in Austria, Czechia and 12 more
- Volunteers
- 311 people
- Sponsor
- Merz Pharmaceuticals GmbH
Stroke, Spastic Hemiplegia
BTX-A and Mirror Therapy for Chronic Stroke Spasticity
Stroke is one of the leading causes of disability worldwide, particularly affecting the upper extremities and thus negatively impacting patients' activities of daily living and quality of life.
- Trial name
- NCT07331844
- Testing
- Botulinum toxin type A (Botox®, Allergan), Mirror Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital