Clinical trials: Spastic Cerebral Palsy
Spastic Diplegia, Periventricular Leukomalacia
Randomized Controlled Trial of Early Intensive Leg Exercise to Improve Walking in Children With Diplegia
This is a randomized controlled trial, comparing 3 months of intensive leg exercise to standard physiotherapy care for the improvement of gross motor function in young children with spastic diplegia.
- Trial name
- NCT03672877
- Testing
- Intensive exercise
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University of Alberta
Cerebral Palsy, Family Characteristics
Functionality and Family Characteristics in Children With Cerebral Palsy
The aim of this study was to investigate the effect of family characteristics on functional level in children with Spastic Type Cerebral Palsy who are able to walk.
- Trial name
- NCT06439446
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Cerebral Palsy, Spastic, Cerebral Palsy
The Validity and Reliability of the Turkish Version of TASC and the Relationship Between SMC and Motor Functions
Selective motor control (SMC) impairment in children with cerebral palsy (CP) includes movement patterns dominated by flexor or extensor synergy affecting functional movements.
- Conditions
- Cerebral Palsy, Spastic, Cerebral Palsy, Cerebral Palsy Spastic Diplegia, Cerebral Palsy Quadriplegic
- Trial name
- NCT04231227
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Gazi University
Cerebral Palsy, Cerebral Palsy, Spastic
Effects of Hand and Arm Bimanual Intensive Therapy Including Lower Extremity in Spastic Cerebral Palsy
Cerebral palsy (CP), particularly the spastic diplegic subtype, is characterized by motor impairments such as spasticity and mobility limitations.
- Trial name
- HABIT-ILE (NCT07253857)
- Testing
- GROUP -A , Hand and Arm Bimanual Intensive Therapy Including Lower Extremity, GROUP-B , Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Cerebral Palsy (CP), Spastic Diplegia Cerebral Palsy
Effect of Reactive Functional Motor Challenge Training on Dynamic Balance and Functional Mobility in Children With Spastic Diplegic Cerebral Palsy: A Randomized Comparative Trial.
To investigate the effect of Reactive Functional Motor Challenge Training on dynamic balance and functional mobility in children with spastic diplegic cerebral palsy.
- Trial name
- NCT07732881
- Testing
- Reactive Functional Motor Challenge Training, Conventional Physical Therapy Program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Badr University
Spasticity, Spasticity in Participants With Multiple Sclerosis
Nerve Root Block in Spasticity
In this work the investigators propose to briefly apply kilohertz frequency alternating current via PNS device placed next to the isolated nerve in 4 patients undergoing peripheral neurectomy, just before cutting the nerve.
- Conditions
- Spasticity, Spasticity in Participants With Multiple Sclerosis, Spasticity Post Stroke, Spasticity Related to Any Cause Except Cerebral Palsy
- Trial name
- NCT06868342
- Testing
- High-frequency nerve conduction block
- Where
- United Kingdom
- Volunteers
- 4 people
- Sponsor
- Walton Centre NHS Foundation Trust
Cerebral Palsy, Congenital
CIMT and BIMT Affect Functional Outcome in CP
The aim of this randomized controlled trial is to determine the effects of constraint induced movement therapy CIMT and BIM bimanual activities on functional outcome in hemiplegic CP.
- Trial name
- NCT04211623
- Testing
- Constraint induced movement therapy, Bimanual activities
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Spastic Quadriplegia, Cerebral Palsy (CP)
Focused Versus Radial Extracorporeal Shock Wave Therapy on Gastrocnemius Spasticity in Children With Spastic Quadriplegic Cerebral Palsy
The goal of this pilot randomized controlled trial is to compare the effectiveness of focused extracorporeal shockwave therapy (ESWT) versus radial ESWT on gastrocnemius spasticity in children with spastic quadriplegic cerebral…
- Conditions
- Spastic Quadriplegia, Cerebral Palsy (CP), Gastrocnemius Muscle
- Trial name
- NCT07894003
- Testing
- Focused Extracorporeal Shock Wave Therapy, Radial Extracorporeal Shock Wave Therapy
- Where
- Indonesia
- Volunteers
- 16 people
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Gait, Spastic Diplegia
Efficacy of Combination Taping Technique vs Ankle Foot Orthosis on Improving Gait Parameters in Cerebral Palsy
Gait in children with spastic CP is often characterized by abnormal gait kinematics as knee flexion and equines foot which associated with such gait deviations, an elevated walking energy cost is often observed which may…
- Trial name
- NCT04839939
- Testing
- Conventional physical therapy, Ankle Foot Orthosis, Combination Taping
- Where
- Saudi Arabia
- Volunteers
- 36 people
- Sponsor
- Batterjee Medical College
Cerebral Palsy, Spastic
Investigation of Motor Imaging Skills in Children With Spastic Cerebral Palsy
The aim of this study was to investigate implicit and explicit motor imagery skills in children with spastic cerebral palsy and typically developing children.
- Trial name
- NCT06343701
- Testing
- Implicit motor imagery, Explicit motor imagery
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Cerebral Palsy
Distal Rectus Femoris Transfer as a Part of Multilevel Surgery in Children With Spastic Diplegia
The purpose of this study is to evaluate the effects of an additional distal rectus femoris transfer carried out as a part of single-event multilevel surgery in children with spastic diplegic cerebral palsy.
- Trial name
- RectusTrans (NCT01381198)
- Testing
- Distal rectus femoris transfer
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- Heidelberg University
Cerebral Palsy, Spastic, Gait Disorders, Neurologic
Reliability of a Body-worn Sensor System for Gait Analysis in Children With CP
Cerebral palsy (CP) is caused by a non-progressive injury in the developing brain, which leads to problems in functional mobility, posture, neuro musculoskeletal functions and gait.
- Trial name
- NCT04240275
- Testing
- Reliability of the G-Walk device in children with Cerebral Palsy
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Gazi University
Cerebral Palsy, Spastic
The Efficacy of Distortion Banding on Outcome Measures in Children With Cerebral Palsy
The aim of the study is to compare the conventional rehabilitation program and the distortion taping applied with Kinesio Tex tape in addition to conventional rehabilitation in children with hemiplegic or monoplegic cerebral…
- Trial name
- NCT05251532
- Testing
- Kinesio Taping, Conventional Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Muğla Sıtkı Koçman University
Muscle Spasticity
The Efficacy and Safety of MEDITOXIN® in Children With Cerebral Palsy
The purpose of this study is to evaluate the efficacy and safety of Meditoxin® in the treatment of children with cerebral palsy.
- Trial name
- NCT01256021
- Testing
- Botulinum Toxin Type A
- Where
- 4 sites in South Korea
- Volunteers
- 212 people
- Sponsor
- Medy-Tox
Shoulder Pain, Shoulder Impingement
Efficacy Of Platelet Rich Plasma In The Treatment Of Hemiplegıc Shoulder Pain
In this study assessing whether platelet rich plasma injections(PRP) are effective in the management hemiplegic shoulder pain, 55 patients with hemiplegic shoulder pain was recruited to this randomized controlled study.
- Conditions
- Shoulder Pain, Shoulder Impingement, Hemiplegia, Infantile, Shoulder Subluxation
- Trial name
- NCT03931824
- Testing
- PRP, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Ege University
Lower Limb and Combined Lower Limb and Upper Limb Spasticity Due to Cerebral Palsy
Long-term Open-label Study of Botulinumtoxin Type A to Treat Spasticity of Leg(s) or Leg(s) and Arm in Cerebral Palsy
The purpose of this study is to determine whether injections of Botulinum toxin type A into muscles of the leg(s) or of leg(s) and one arm are safe in treating children/adolescents (age 2-17 years) long-term with increased muscle…
- Trial name
- NCT01905683
- Testing
- IncobotulinumtoxinA (16-20 Units per kg body weight)
- Where
- 43 sites in Austria, Czechia and 10 more
- Volunteers
- 370 people
- Sponsor
- Merz Pharmaceuticals GmbH
Cerebral Palsy (CP)
The Effect of Hip Joint Orthotic Intervention and Conventional Exercise Training on Spasticity, Balance and Walking Performance in Children With Cerebral Palsy
Cerebral palsy (SP) is defined as a group of persistent disorders that cause activity limitation of movement and postural development. Children with cerebral palsy are typically born with a normal anatomical hip sequence.
- Trial name
- NCT07000578
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people
- Sponsor
- Medipol University
Spinocerebellar Ataxias, Spastic Paraplegias
Natural History, Genetic Bases and Phenotype-genotype Correlations in Autosomal Dominant Spinocerebellar Degenerations
The autosomal dominant spinocerebellar degenerations are a highly heterogeneous, clinically and genetically, group of rare diseases and of severe evolution.
- Trial name
- NCT00136630
- Where
- 8 sites in France
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Hemiplegia, Stroke
Mirror vs Virtual Reality Therapy for Upper Extremity Function in Hemiplegic Patients
Upper extremity impairment in hemiplegic patients significantly impacts daily activities and reduces quality of life. Although traditional rehabilitation methods can help, some patients experience limited progress.
- Conditions
- Hemiplegia, Stroke, Upper Extremity Dysfunction
- Trial name
- NCT07018336
- Testing
- Mirror Therapy, Virtual Reality (VR) Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istinye University
Cerebral Palsy (CP)
Effect of IASTM in Children With Diplegia
The aim was to evaluate the effect of using IASTM on passive ROM of the lower limbs and joint angles during gait in children with spastic diplegic CP.
- Trial name
- NCT07289386
- Testing
- IASTM therapy in addition to the selected physical therapy program, selected physical therapy program
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University