Clinical trials: Spastic Diplegia
Cerebral Palsy, Spastic
The Effectiveness of Repetitive Transcranial Magnetic Stimulation for Spastic Diplegia Cerebral Palsy
Cerebral palsy describes a group of permanent disorders of the development of movement and posture, causing activity limitation that are attributed to non-progressive disturbances that occurred in the developing fetal or infant…
- Trial name
- NCT05198921
- Testing
- repetitive Transcranial Magnetic Stimulation
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universitat de Lleida
Sjogren-Larsson Syndrome (SLS)
Sjogren-Larsson Syndrome: Natural History, Clinical Variation and Evaluation of Biochemical Markers
Sjogren-Larsson syndrome (SLS) is a rare genetic disease in which patients typically exhibit ichthyosis (dry, scaly skin), intellectual disability, spasticity, seizures and a distinctive maculopathy.
- Trial name
- SLS (NCT01971957)
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Nebraska
HIV Infections
A Study of Zidovudine (AZT) Used Alone or in Combination With Other Anti-HIV Drugs in HIV-Infected Patients With Little or No Previous Treatment
To compare, in zidovudine (AZT)-naive patients, the safety, tolerance, and efficacy of saquinavir mesylate (Ro 31-8959) alone versus AZT alone versus AZT in combination with Ro 31-8959, zalcitabine (ddC), or both.
- Trial name
- NCT00002334
- Testing
- Saquinavir, Zidovudine, Zalcitabine
- Where
- 26 sites in United States, Puerto Rico
- Volunteers
- 3,000 people
- Sponsor
- Hoffmann-La Roche
Cerebral Palsy Spastic Diplegia
Effect of Leg Pedalling Exercise From Inclined Position
Statement of the problem:- Does the lower limb pedalling exercise from inclined position improve functional ability and trunk control in children with diplegic cerebral palsy? Null Hypothesis:- There will be no effect of lower…
- Trial name
- NCT06233136
- Testing
- Leg pedalling exercise, The designed physical therapy program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Cerebral Palsy Spastic Diplegia
Neck-Trunk Stabilization Exercises and Bobath Therapy Spastic Diplegic Cerebral Palsy
Physiotherapy is widely used in the treatment of children with cerebral palsy. This study is conducted to identify the most appropriate physiotherapy approach.
- Trial name
- NCT05707052
- Testing
- Neck-Trunk Stabilization Exercises and conventional physical therapy, Bobath Therapy and conventional physical therapy
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Spastic Diplegia, Motor Imagery
Effect of Multisensory Motor Imagery Training on Muscle Performance and Coordination in Children With Spastic Diplegia
PURPOSE: The current study aims to: Determine the effect of multisensory motor imagery training on muscle performance including (peak torque, work, power) of trunk and knee flexors and extensors in children with spastic diplegia.
- Trial name
- NCT06676332
- Testing
- motor imagery training, traditional physical therapy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Cerebral Palsy
Dual Task Training in Spastic Cerebral Palsy
This study aims to investigate the effects of dual task training on gait and balance parameters, gross motor function skills, functional mobility skills, functional independence levels and health-related quality of life o in…
- Trial name
- NCT04263701
- Testing
- Therapeutic exercises, Dual Task Training
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Kutahya Health Sciences University
Spastic Diplegic Cerebral Palsy
Efficacy and Functional Outcomes of Botulinum Toxin A Injections to Hamstrings in Flexed Knee Gait in Cerebral Palsy
The study proposes to determine if injections of BTX-A to the hamstring muscles result in measurable physiologic changes not observed with normal saline injections in children with spastic diplegic cerebral palsy who walk with a…
- Trial name
- NCT00261131
- Testing
- Botulinum Toxin A
- Volunteers
- 250 people
- Sponsor
- Shriners Hospitals for Children
Tobacco Use Disorder, Dual Tobacco Use
Addictive Potential of LCCs in Dual Users
This study is about whether or not little cigars and cigarillos cause or maintain addiction, and if flavors, such as fruit, make them more addictive.
- Conditions
- Tobacco Use Disorder, Dual Tobacco Use, Tobacco Dependence, Smoking
- Trial name
- NCT03496077
- Testing
- Flavored and unflavored little cigars/cigarillos (LCCs)
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- UConn Health
Cerebral Palsy
Moderate Versus High-intensity Interval Training in Children With Diplegia.
The aim is to compare the effects of moderate-intensity training and high-intensity interval training on gait, energy expenditure, and functional mobility in children with spastic diplegia.
- Trial name
- NCT07289373
- Testing
- Moderate intensity training, High intensity interval training
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Spastic Diplegia Cerebral Palsy, Spastic Hemiplegia
Spinal Mobility in Children With Cerebral Palsy: NDT-Bobath and Exergaming
The purpose of this study is to evaluate changes in spinal mobility in the cervical, thoracic, and lumbar regions in children with cerebral palsy aged 10-15 years.
- Trial name
- NCT07421505
- Testing
- NDT-Bobath Therapy, Sitting Exergaming, Standing Exergaming
- Where
- 2 sites in Poland
- Volunteers
- 42 people
- Sponsor
- Wroclaw University of Health and Sport Sciences
Cerebral Palsy Spastic Diplegia
Hippotherapy Versus Swiss Ball Training to Improve Trunk Control and Balance on Spastic Daiplegic Cerebral Palsy
To compare effect in both intervention
- Trial name
- NCT06047756
- Testing
- Hippotherapy, Swiss Ball therapy
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Riphah International University
Spastic Diplegic Cerebral Palsy
Effects of Transcranial Direct Current Stimulation Combined With Virtual Reality on Gait and Self-Esteem in Children With Spastic Cerebral Palsy
Cerebral palsy can affect walking ability, muscle control, functional mobility, and psychosocial well-being in children. Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that may…
- Trial name
- NCT07829796
- Testing
- Active Transcranial Direct Current Stimulation, Virtual Reality Rehabilitation, Conventional Physical Therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Spastic Diplegic Cerebral Palsy, Gait, Spastic
Effects of LIFT on Gait and Balance in Spastic Diplegic Cerebral Palsy Children
The goal of this Randomized control trial was to evaluate the outcome of limb intensive functional training (LIFT) on gait and balance in spastic diplegic cerebral palsy children with age 3-7 years.
- Trial name
- NCT07121426
- Testing
- Lower limb Intensive Functional Training, Conventional physical therapy
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- University of Lahore
Cerebral Palsy (CP), Diplegic Cerebral Palsy
Effect of Intensive Segmental Trunk Training on Upper Extremity Function and Seated Postural Stability in Children With Spastic Diplegic Cerebral Palsy
The goal of this randomized controlled trial is to evaluate whether intensive segmental trunk training (ISTT) can improve upper extremity function and seated postural stability in children aged 4-12 years with spastic diplegic…
- Conditions
- Cerebral Palsy (CP), Diplegic Cerebral Palsy, Trunk Mobility, Upper Extremity Function
- Trial name
- NCT07692087
- Testing
- Intensive Segmental Trunk Training, Standard Physical Therapy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Lahore
Mothers of Children With Colostomy, A Multi-component Educational Program
Effectiveness of a Digital Educational Booklet on Mothers' Colostomy Care Knowledge and Practices
This study aimed to evaluate the effectiveness of a digital education and simulation-supported training intervention on mothers' knowledge and practices regarding colostomy care for their children.
- Conditions
- Mothers of Children With Colostomy, A Multi-component Educational Program, Digital Booklet, WhatsApp
- Trial name
- NCT07662707
- Testing
- digital education and simulation-supported training intervention
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- King Saud Bin Abdulaziz University for Health Sciences
Cerebral Palsy, Spastic Diplegia
Gait Rehabilitation in Diplegic Children
Background: Standing and walking serve an individual's basic need to move from place to place, and both are the most common activities that people do on a daily basis.
- Trial name
- NCT05294874
- Testing
- gait training
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Spastic Diplegia
Role of Dynamic Movement Intervention in Children with Spastic Diplegia
The study aims to investigate the effect of dynamic movement intervention approach on static and dynamic balance, quality of step length and cadence of walking pattern of children with spastic diplegic cerebral palsy.
- Trial name
- NCT06270550
- Testing
- Dynamic Movement Intervention
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Behavior, Anxiety
Tutorial of Clinical Trial Registration
The present study aimed to determine whether infants disorders of regulation of states are associated with perinatal anxiety, and further to explore the efficacy of the behavioral intervention in enhancing positive interactions…
- Trial name
- CTREG (NCT03481452)
- Testing
- psychotherapy
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Gait, Spastic
Effect of Weight on Hip Excursion During Gait
Background: Children with diplegia had considerably larger hip and knee excursion during gait cycle than did normal developing children.
- Trial name
- NCT05579535
- Testing
- gait training exercises
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University